neostigmine has been researched along with Sepsis in 4 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sepsis strengthened the antagonistic actions of neostigmine on Roc-depressed twitch tension of the diaphragm by inhibiting the activity of AChE in the NMJ." | 7.83 | Sepsis Strengthens Antagonistic Actions of Neostigmine on Rocuronium in a Rat Model of Cecal Ligation and Puncture. ( Jin, T; Li, ST; Wang, H; Wu, J, 2016) |
| "Sepsis strengthened the antagonistic actions of neostigmine on Roc-depressed twitch tension of the diaphragm by inhibiting the activity of AChE in the NMJ." | 3.83 | Sepsis Strengthens Antagonistic Actions of Neostigmine on Rocuronium in a Rat Model of Cecal Ligation and Puncture. ( Jin, T; Li, ST; Wang, H; Wu, J, 2016) |
| "Treatment with physostigmine significantly reduced lethality (p < or = ." | 1.35 | Pharmacologic cholinesterase inhibition improves survival in experimental sepsis. ( Bierhaus, A; Bode, K; Brueckmann, M; Dalpke, AH; Eisenbach, C; Encke, J; Hofer, S; Krammer, PH; Lukic, IK; Martin, E; Mautner, S; Nawroth, PP; Schneider, L; Stremmel, W; Weigand, MA; Wente, MN; Werner, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, J | 1 |
| Jin, T | 1 |
| Wang, H | 1 |
| Li, ST | 1 |
| Zabrodskii, PF | 1 |
| Lim, VG | 1 |
| Kuzmin, AV | 1 |
| Hofer, S | 1 |
| Eisenbach, C | 1 |
| Lukic, IK | 1 |
| Schneider, L | 1 |
| Bode, K | 1 |
| Brueckmann, M | 1 |
| Mautner, S | 1 |
| Wente, MN | 1 |
| Encke, J | 1 |
| Werner, J | 1 |
| Dalpke, AH | 1 |
| Stremmel, W | 1 |
| Nawroth, PP | 1 |
| Martin, E | 1 |
| Krammer, PH | 1 |
| Bierhaus, A | 1 |
| Weigand, MA | 1 |
| Narimatsu, E | 1 |
| Nakayama, Y | 1 |
| Sumita, S | 1 |
| Iwasaki, H | 1 |
| Fujimura, N | 1 |
| Satoh, K | 1 |
| Namiki, A | 1 |
4 other studies available for neostigmine and Sepsis
| Article | Year |
|---|---|
Sepsis Strengthens Antagonistic Actions of Neostigmine on Rocuronium in a Rat Model of Cecal Ligation and Puncture.
Topics: Acetylcholinesterase; Androstanols; Animals; Cecum; Cholinesterase Inhibitors; Diaphragm; Disease Mo | 2016 |
Effects of reversible inhibition of cholinesterase and nicotine on mouse mortality and blood levels of proinflammatory cytokines during the early phase of sepsis.
Topics: Animals; Animals, Outbred Strains; Cholinesterase Inhibitors; Drug Therapy, Combination; Escherichia | 2012 |
Pharmacologic cholinesterase inhibition improves survival in experimental sepsis.
Topics: Animals; Cholinesterase Inhibitors; Cytokines; Disease Models, Animal; Female; Inflammation Mediator | 2008 |
Sepsis attenuates the intensity of the neuromuscular blocking effect of d-tubocurarine and the antagonistic actions of neostigmine and edrophonium accompanying depression of muscle contractility of the diaphragm.
Topics: Animals; Cholinesterase Inhibitors; Diaphragm; Dose-Response Relationship, Drug; Edrophonium; In Vit | 1999 |