chlorpromazine has been researched along with Sepsis in 19 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Agranulocytosis, a severe decrease or absence of neutrophils, is a side effect of several medications, including chlorpromazine." | 8.12 | A Medication Hiccup: Chlorpromazine-Induced Agranulocytosis in a 72-Year-Old Male. ( Kobylarz, Z; Lambert, D; Nothem, ME; Scholcoff, C, 2022) |
| "Agranulocytosis, a severe decrease or absence of neutrophils, is a side effect of several medications, including chlorpromazine." | 4.12 | A Medication Hiccup: Chlorpromazine-Induced Agranulocytosis in a 72-Year-Old Male. ( Kobylarz, Z; Lambert, D; Nothem, ME; Scholcoff, C, 2022) |
| "Symptoms and clinical presentations of OTC deficiency vary widely according to the remaining activity of the enzyme." | 1.51 | Malnutrition with hypoaminoacidemia in a 22-year-old pregnant patient masking a likely ornithine transcarbamylase deficiency. ( Chartier, M; Cynober, L; Lefrère, B; Neveux, N; Patkaï, J; Ulmann, G, 2019) |
| "We present a patient with neuroleptic malignant syndrome and intestinal pseudo-obstruction misdiagnosed as being secondary to septicaemia." | 1.28 | Neuroleptic malignant syndrome: another medical cause of acute abdomen. ( Dymock, IW; Lo, TC; Unwin, MR, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (84.21) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Lambert, D | 1 |
| Nothem, ME | 1 |
| Kobylarz, Z | 1 |
| Scholcoff, C | 1 |
| Lefrère, B | 1 |
| Ulmann, G | 1 |
| Chartier, M | 1 |
| Patkaï, J | 1 |
| Cynober, L | 1 |
| Neveux, N | 1 |
| GELFAND, M | 1 |
| CALDEYRO-BARCIA, R | 1 |
| POSEIRO, JJ | 1 |
| ALVAREZ, H | 1 |
| TOST, P | 1 |
| BENNETT, NM | 1 |
| KURZ, GH | 1 |
| ADAMS, EB | 1 |
| HOLLOWAY, R | 1 |
| THAMBIRAN, AK | 1 |
| SAMBHI, MP | 1 |
| WEIL, MH | 1 |
| UDHOJI, VN | 1 |
| ROSOFF, L | 1 |
| WOROBEC, T | 1 |
| Loeb, HS | 1 |
| Cruz, A | 1 |
| Teng, CY | 1 |
| Boswell, J | 1 |
| Pietras, RJ | 1 |
| Tobin, JR | 1 |
| Gunnar, RM | 1 |
| Antia-Obong, OE | 1 |
| Ekanem, EE | 1 |
| Udo, JJ | 1 |
| Utsalo, SJ | 1 |
| Lo, TC | 1 |
| Unwin, MR | 1 |
| Dymock, IW | 1 |
| Niklasson, PM | 1 |
| Blombäck, M | 1 |
| Lundbergh, P | 1 |
| Strandell, T | 1 |
| Lambotte, L | 1 |
| Rocmans, P | 1 |
| Nichols, MM | 1 |
| Meyer, W | 2 |
| Popenenkova, ZA | 1 |
| Romanovskaia, MG | 1 |
| Johnson, DG | 1 |
2 reviews available for chlorpromazine and Sepsis
| Article | Year |
|---|---|
[Cliniccal aspects, pathogenesis and therapy of shock due to sepsis caused by gram-negative organisms].
Topics: Adult; Animals; Blood; Chlorpromazine; Diarrhea; Dogs; Electrocardiography; Endotoxins; Escherichia | 1966 |
[Clinical aspects, pathogenesis and therapy of shock due to sepsis caused by gram-negative organisms].
Topics: Adult; Aldosterone; Animals; Blood; Chlorpromazine; Diarrhea; Dogs; Electrocardiography; Endotoxins; | 1966 |
17 other studies available for chlorpromazine and Sepsis
| Article | Year |
|---|---|
A Medication Hiccup: Chlorpromazine-Induced Agranulocytosis in a 72-Year-Old Male.
Topics: Aged; Agranulocytosis; Chlorpromazine; Hiccup; Humans; Male; Sepsis | 2022 |
Malnutrition with hypoaminoacidemia in a 22-year-old pregnant patient masking a likely ornithine transcarbamylase deficiency.
Topics: Anti-Bacterial Agents; Antiemetics; Chlorpromazine; DNA Mutational Analysis; Female; Humans; Infant, | 2019 |
Three cases of tetanus neonatorum successfully treated with chlorpromazine, tetanus antiserum and penicillin.
Topics: Child; Chlorpromazine; Humans; Immune Sera; Infant; Infant, Newborn; Infant, Newborn, Diseases; Peni | 1955 |
The action of chlorpromazine on uterine contractility and arterial pressure in normal and toxemic pregnant women.
Topics: Blood Pressure; Blood Pressure Determination; Chlorpromazine; Female; Humans; Muscle Contraction; Pr | 1958 |
DRUG-INDUCED AGRANULOCYTOSIS AND SEPTICAEMIA.
Topics: Agranulocytosis; Antipsychotic Agents; Benzene; Chlorpromazine; Methylthiouracil; Phenothiazines; Ph | 1963 |
RETINOPATHY OF OBSCURE (TOXIC?) ORIGIN IN HODGKIN'S DISEASE.
Topics: Anemia; Chloramphenicol; Chlorpromazine; Eye; Glutethimide; Herpes Zoster; Herpes Zoster Ophthalmicu | 1964 |
SOME MODIFICATIONS IN METHOD OF TREATING TETANUS NEONATORUM WITH INTERMITTENT POSITIVE-PRESSURE RESPIRATION.
Topics: Biomedical Research; Chlorpromazine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Mus | 1964 |
EFFECT OF PRESSOR AMINES ON CARDIAC OUTPUT IN PATIENTS WITH ACUTE HYPOTENSION.
Topics: Amines; Barbiturates; Blood Pressure; Cardiac Output; Chlorpromazine; Dehydration; Drug Therapy; Dye | 1964 |
BLOOD DYSCRASIAS ASSOCIATED WITH ANTITUBERCULOSIS AND/OR TRANQUILIZING CHEMOTHERAPY. A LONG-TERM CLINICAL OBSERVATION.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver In | 1965 |
Haemodynamic studies in shock associated with infection.
Topics: Aged; Blood Pressure; Blood Volume; Cardiac Output; Chlorpromazine; Dextrans; Digitalis Glycosides; | 1967 |
Septicaemia among neonates with tetanus.
Topics: Ampicillin; Chlorpromazine; Comorbidity; Female; Gentamicins; Humans; Infant, Newborn; Male; Nigeria | 1992 |
Neuroleptic malignant syndrome: another medical cause of acute abdomen.
Topics: Abdomen, Acute; Adult; Chlorpromazine; Diagnostic Errors; Female; Flupenthixol; Humans; Intestinal P | 1989 |
Thrombocytopenia and bleeding complications in severe cases of meningococcal infection treated with heparin, dextran 70 and chlorpromazine.
Topics: Adolescent; Adult; Aspirin; Blood Platelet Disorders; Cephalothin; Chlorpromazine; Dexamethasone; De | 1972 |
[Toxi-infectious shock].
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Blood Transfusion; Chlorpromazine; Digitalis G | 1973 |
Managing emergencies in the newborn.
Topics: Anesthesia, Obstetrical; Anti-Bacterial Agents; Apnea; Bronchopneumonia; Chlorpromazine; Cyclopropan | 1974 |
[The effect of vetrazine, chlorazicin and eminazine on bacterial infection].
Topics: Animals; Chlorpromazine; Escherichia coli; Escherichia coli Infections; Hydrazines; Monoamine Oxidas | 1969 |
Shock and its management.
Topics: Anti-Bacterial Agents; Anticoagulants; Blood Cell Count; Blood Pressure; Blood Transfusion; Body Wei | 1969 |