Condition | Indicated | Relationship Strength | Studies | Trials |
Congenital Zika Syndrome [description not available] | 0 | 2.25 | 1 | 0 |
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 4.27 | 16 | 0 |
Zika Virus Infection A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME. | 0 | 2.25 | 1 | 0 |
Breast Cancer [description not available] | 0 | 7.54 | 2 | 0 |
Breast Neoplasms Tumors or cancer of the human BREAST. | 0 | 2.54 | 2 | 0 |
Aqueductal Stenosis [description not available] | 0 | 2.41 | 1 | 0 |
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 2.58 | 2 | 0 |
Low Bone Density [description not available] | 0 | 2.41 | 1 | 0 |
Bone Loss, Osteoclastic [description not available] | 0 | 2.59 | 2 | 0 |
Age-Related Osteoporosis [description not available] | 0 | 2.41 | 1 | 0 |
Bone Loss, Perimenopausal [description not available] | 0 | 2.41 | 1 | 0 |
Bone Diseases, Metabolic Diseases that affect the METABOLIC PROCESSES of BONE TISSUE. | 0 | 2.41 | 1 | 0 |
Osteoporosis Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. | 0 | 2.41 | 1 | 0 |
Osteoporosis, Postmenopausal Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency. | 0 | 2.41 | 1 | 0 |
Neointima The new and thickened layer of scar tissue that forms on a PROSTHESIS, or as a result of vessel injury especially following ANGIOPLASTY or stent placement. | 0 | 7.8 | 3 | 0 |
Aneurysm, Arteriovenous [description not available] | 0 | 2.41 | 1 | 0 |
Constriction, Pathological [description not available] | 0 | 2.41 | 1 | 0 |
Constriction, Pathologic The condition of an anatomical structure's being constricted beyond normal dimensions. | 0 | 2.41 | 1 | 0 |
Hyperplasia An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells. | 0 | 7.41 | 1 | 0 |
Acquired-Immune Deficiency Syndrome Dementia Complex [description not available] | 0 | 2.6 | 1 | 0 |
HIV Coinfection [description not available] | 0 | 2.6 | 1 | 0 |
AIDS Dementia Complex A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40) | 0 | 2.6 | 1 | 0 |
HIV Infections Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS). | 0 | 2.6 | 1 | 0 |
Pericementitis [description not available] | 0 | 2.82 | 2 | 0 |
Periodontitis Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology) | 0 | 7.82 | 2 | 0 |
Cerebral Infarction, Middle Cerebral Artery [description not available] | 0 | 2.25 | 1 | 0 |
Infarction, Middle Cerebral Artery NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction. | 0 | 2.25 | 1 | 0 |
Atheroma [description not available] | 0 | 2.66 | 2 | 0 |
Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE. | 0 | 2.31 | 1 | 0 |
Atherogenesis [description not available] | 0 | 2.25 | 1 | 0 |
Liver Steatosis [description not available] | 0 | 2.25 | 1 | 0 |
Innate Inflammatory Response [description not available] | 0 | 3.22 | 5 | 0 |
Insulin Sensitivity [description not available] | 0 | 2.25 | 1 | 0 |
Fatty Liver Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS. | 0 | 2.25 | 1 | 0 |
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 8.22 | 5 | 0 |
Insulin Resistance Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. | 0 | 2.25 | 1 | 0 |
Obesity A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). | 0 | 7.25 | 1 | 0 |
Atherosclerosis A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 2.25 | 1 | 0 |
Hemorrhagic Shock [description not available] | 0 | 2.25 | 1 | 0 |
Carcinogenesis The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. | 0 | 2.53 | 2 | 0 |
Bone Cancer [description not available] | 0 | 7.17 | 1 | 0 |
Experimental Neoplasms [description not available] | 0 | 2.17 | 1 | 0 |
Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES. | 0 | 2.17 | 1 | 0 |
Degenerative Diseases, Central Nervous System [description not available] | 0 | 2.17 | 1 | 0 |
Brain Inflammation [description not available] | 0 | 2.17 | 1 | 0 |
Encephalitis Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition. | 0 | 2.17 | 1 | 0 |
Neurodegenerative Diseases Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures. | 0 | 2.17 | 1 | 0 |
Anterior Optic Neuritis [description not available] | 0 | 2.21 | 1 | 0 |
Optic Neuritis Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis). | 0 | 2.21 | 1 | 0 |
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 2.1 | 1 | 0 |
Animal Mammary Carcinoma [description not available] | 0 | 2.1 | 1 | 0 |
Chickungunya Fever [description not available] | 0 | 2.49 | 2 | 0 |
ADPKD [description not available] | 0 | 2.11 | 1 | 0 |
Proteinuria The presence of proteins in the urine, an indicator of KIDNEY DISEASES. | 0 | 4.12 | 3 | 1 |
Polycystic Kidney, Autosomal Dominant Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function. | 0 | 2.11 | 1 | 0 |
Anoxemia [description not available] | 0 | 2.11 | 1 | 0 |
Pulmonary Hypertension [description not available] | 0 | 2.11 | 1 | 0 |
Blood Clot [description not available] | 0 | 2.11 | 1 | 0 |
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms. | 0 | 2.11 | 1 | 0 |
Hypertension, Pulmonary Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES. | 0 | 2.11 | 1 | 0 |
Thrombosis Formation and development of a thrombus or blood clot in the blood vessel. | 0 | 2.11 | 1 | 0 |
Arteriosclerosis, Coronary [description not available] | 0 | 3.51 | 1 | 1 |
Coronary Artery Disease Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause. | 0 | 3.51 | 1 | 1 |
Coronary Restenosis Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction. | 1 | 5.51 | 1 | 1 |
Benign Psychomotor Epilepsy, Childhood [description not available] | 0 | 2.13 | 1 | 0 |
Epilepsy, Temporal Lobe A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321). | 0 | 2.13 | 1 | 0 |
Arthritis, Degenerative [description not available] | 0 | 2.15 | 1 | 0 |
Osteoarthritis A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. | 0 | 2.15 | 1 | 0 |
Disease Exacerbation [description not available] | 0 | 2.04 | 1 | 0 |
Colitis Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER. | 0 | 7.04 | 1 | 0 |
Carotid Arteriopathies, Traumatic [description not available] | 0 | 2.05 | 1 | 0 |
Hyperlipemia [description not available] | 0 | 2.05 | 1 | 0 |
Hyperlipidemias Conditions with excess LIPIDS in the blood. | 0 | 2.05 | 1 | 0 |
Adjuvant Arthritis [description not available] | 0 | 3.09 | 5 | 0 |
Idiopathic Inflammatory Myopathies [description not available] | 0 | 2.46 | 2 | 0 |
Alpha Virus Infections [description not available] | 0 | 2.46 | 2 | 0 |
Myositis Inflammation of a muscle or muscle tissue. | 0 | 2.46 | 2 | 0 |
Cirrhosis [description not available] | 0 | 2.05 | 1 | 0 |
Goldblatt Syndrome [description not available] | 0 | 2.05 | 1 | 0 |
Nephritis Inflammation of any part of the KIDNEY. | 0 | 2.05 | 1 | 0 |
Renal Artery Stenosis [description not available] | 0 | 2.05 | 1 | 0 |
Fibrosis Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. | 0 | 2.05 | 1 | 0 |
Hypertension, Renovascular Hypertension due to RENAL ARTERY OBSTRUCTION or compression. | 0 | 2.05 | 1 | 0 |
Renal Artery Obstruction Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR). | 0 | 2.05 | 1 | 0 |
Acute Edematous Pancreatitis [description not available] | 0 | 2.44 | 2 | 0 |
Acute Disease Disease having a short and relatively severe course. | 0 | 4.12 | 3 | 1 |
Pancreatitis INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. | 0 | 7.44 | 2 | 0 |
Coronary Artery Stenosis [description not available] | 0 | 2.06 | 1 | 0 |
Coronary Stenosis Narrowing or constriction of a coronary artery. | 0 | 2.06 | 1 | 0 |
Glomerulonephritis, Lupus [description not available] | 0 | 5.01 | 3 | 1 |
Kidney Diseases Pathological processes of the KIDNEY or its component tissues. | 0 | 3.45 | 1 | 1 |
Lupus Nephritis Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982). | 0 | 5.01 | 3 | 1 |
Arthritides, Bacterial [description not available] | 0 | 2.06 | 1 | 0 |
Metastase [description not available] | 0 | 2.07 | 1 | 0 |
Cancer of Prostate [description not available] | 0 | 2.07 | 1 | 0 |
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 2.07 | 1 | 0 |
Prostatic Neoplasms Tumors or cancer of the PROSTATE. | 0 | 2.07 | 1 | 0 |
Benign Neoplasms [description not available] | 0 | 2.99 | 1 | 0 |
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 2.99 | 1 | 0 |
Allergic Encephalomyelitis [description not available] | 0 | 2.07 | 1 | 0 |
Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 2.02 | 1 | 0 |
B16 Melanoma [description not available] | 0 | 2.03 | 1 | 0 |
Angiogenesis, Pathologic [description not available] | 0 | 2.03 | 1 | 0 |
Blood Poisoning [description not available] | 0 | 2.04 | 1 | 0 |
Primary Peritonitis [description not available] | 0 | 2.04 | 1 | 0 |
Peritonitis INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs. | 0 | 2.04 | 1 | 0 |
Sepsis Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. | 0 | 2.04 | 1 | 0 |
Endotoxemia A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators. | 0 | 2.04 | 1 | 0 |
Rheumatism [description not available] | 0 | 2 | 1 | 0 |
Rheumatic Diseases Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement. | 0 | 2 | 1 | 0 |
Acute-Phase Reaction An early local inflammatory reaction to insult or injury that consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma. | 0 | 1.98 | 1 | 0 |