dimethyl sulfoxide has been researched along with Sepsis in 12 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, we evaluated whether the pharmacological properties of 6-gingerol (6G) and 10-gingerol (10G) could modulate AKI and metabolic disruption in a rat model of sepsis (faecal peritonitis)." | 7.88 | Gingerol suppresses sepsis-induced acute kidney injury by modulating methylsulfonylmethane and dimethylamine production. ( Brito, GAC; da Silva, JA; de Medeiros, PHQS; Dos Santos, AA; Havt, A; Lima, AÂM; Prata, MMG; Rodrigues, FAP; Santos, ADDC; Santos, TCS; Silveira, ER, 2018) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Twenty-four male C57BL/6 mice were divided into three groups randomly: sham operated group, sepsis model group [cecum ligation and puncture (CLP)+dimethyl sulfoxide (DMSO) group] and EZH2 selective inhibitor treated group (CLP+GSK126 group), with 8 mice in each group." | 4.12 | [Effects and molecular mechanism of histone methyltransferase enhancer of zeste homolog 2 on regulating sepsis-induced T cell dysfunction]. ( Li, Z; Tang, L; Zhao, D; Zhou, X, 2022) |
| " Therefore, we evaluated whether the pharmacological properties of 6-gingerol (6G) and 10-gingerol (10G) could modulate AKI and metabolic disruption in a rat model of sepsis (faecal peritonitis)." | 3.88 | Gingerol suppresses sepsis-induced acute kidney injury by modulating methylsulfonylmethane and dimethylamine production. ( Brito, GAC; da Silva, JA; de Medeiros, PHQS; Dos Santos, AA; Havt, A; Lima, AÂM; Prata, MMG; Rodrigues, FAP; Santos, ADDC; Santos, TCS; Silveira, ER, 2018) |
| "Dimethyl sulfoxide (DMSO) is an amphipathic molecule that is commonly/widely used as a solvent for biological compounds." | 1.40 | Dimethyl sulfoxide inhibits NLRP3 inflammasome activation. ( Ahn, H; Jeung, EB; Kim, J; Lee, GS, 2014) |
| "Dimethyl sulfoxide (DMSO) is a potent antioxidant which protects against endotoxemia and septic shock in animal models." | 1.31 | Therapeutic effect of dimethyl sulfoxide on ICAM-1 gene expression and activation of NF-kappaB and AP-1 in septic rats. ( Albarillo, MV; Chang, CK; Schumer, W, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 4 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, W | 1 |
| Ao, S | 1 |
| Zhou, J | 1 |
| Li, J | 1 |
| Liang, X | 1 |
| Yang, X | 2 |
| Zhang, H | 1 |
| Liu, B | 2 |
| Tang, W | 1 |
| Liu, H | 1 |
| Xiao, H | 1 |
| Liang, H | 1 |
| Li, Z | 1 |
| Zhao, D | 1 |
| Zhou, X | 1 |
| Tang, L | 1 |
| Li, L | 1 |
| Li, Y | 2 |
| Lu, N | 1 |
| Du, R | 1 |
| Li, W | 1 |
| Ye, H | 1 |
| Gao, Q | 1 |
| Rodrigues, FAP | 1 |
| Santos, ADDC | 1 |
| de Medeiros, PHQS | 1 |
| Prata, MMG | 1 |
| Santos, TCS | 1 |
| da Silva, JA | 1 |
| Brito, GAC | 1 |
| Dos Santos, AA | 1 |
| Silveira, ER | 1 |
| Lima, AÂM | 1 |
| Havt, A | 1 |
| Ahn, H | 1 |
| Kim, J | 1 |
| Jeung, EB | 1 |
| Lee, GS | 1 |
| Marchetti, C | 1 |
| Mezzaroma, E | 1 |
| Toldo, S | 1 |
| Zhao, T | 1 |
| Halaweish, I | 1 |
| Mazitschek, R | 1 |
| Duan, X | 1 |
| Alam, HB | 1 |
| Macdonald, J | 1 |
| Galley, HF | 1 |
| Webster, NR | 1 |
| Borovik, PI | 1 |
| Troshkov, AA | 1 |
| Bova, LS | 1 |
| Konovart, BN | 1 |
| Borovik, GA | 1 |
| Korotkiĭ, VN | 1 |
| Geleskul, VF | 1 |
| Kolosovich, IV | 1 |
| Butyrin, SA | 1 |
| Chang, CK | 1 |
| Albarillo, MV | 1 |
| Schumer, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oxidative Stress Response in Patients With Severe Aortic Stenosis Undergoing Transcatheter or Surgical Aortic Valve Replacement (ROS Study)[NCT02841917] | 3 participants (Actual) | Observational | 2016-11-29 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for dimethyl sulfoxide and Sepsis
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Oxidative stress and gene expression in sepsis.
Topics: Animals; Antioxidants; Ascorbic Acid; Binding Sites; Dimethyl Sulfoxide; Gene Expression; Gene Expre | 2003 |
1 trial available for dimethyl sulfoxide and Sepsis
10 other studies available for dimethyl sulfoxide and Sepsis
| Article | Year |
|---|---|
Methylsulfonylmethane protects against lethal dose MRSA-induced sepsis through promoting M2 macrophage polarization.
Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Macrophage Activation; Macrophages; Methicillin | 2022 |
[Effects and molecular mechanism of histone methyltransferase enhancer of zeste homolog 2 on regulating sepsis-induced T cell dysfunction].
Topics: Animals; B7-H1 Antigen; Dimethyl Sulfoxide; Enhancer of Zeste Homolog 2 Protein; Histone Methyltrans | 2022 |
[Mitochondrial aldehyde dehydrogenase 2 alleviates septic liver injury by inhibiting ferroptosis in mouse model].
Topics: Aldehyde Dehydrogenase, Mitochondrial; Animals; Chemical and Drug Induced Liver Injury, Chronic; Dim | 2023 |
Gingerol suppresses sepsis-induced acute kidney injury by modulating methylsulfonylmethane and dimethylamine production.
Topics: Acute Kidney Injury; Animals; Catechols; Dimethyl Sulfoxide; Dimethylamines; Disease Models, Animal; | 2018 |
Dimethyl sulfoxide inhibits NLRP3 inflammasome activation.
Topics: Animals; Anti-Inflammatory Agents; Calcium-Binding Proteins; CARD Signaling Adaptor Proteins; Carrie | 2014 |
Effects of dimethyl sulfoxide on the NLRP3 inflammasome.
Topics: Animals; Anti-Inflammatory Agents; Carrier Proteins; Dimethyl Sulfoxide; Humans; Inflammasomes; Infl | 2015 |
Inhibition of histone deacetylase 6 improves long-term survival in a lethal septic model.
Topics: Animals; Benzamides; Blotting, Western; Cytokines; Dimethyl Sulfoxide; Disease Models, Animal; Enzym | 2015 |
[Treatment of septicopyemic forms of acute hematogenic osteomyelitis using dimexide and hyperbaric oxygenation].
Topics: Acute Disease; Child; Child, Preschool; Dimethyl Sulfoxide; Female; Humans; Hyperbaric Oxygenation; | 1981 |
[The prevention and treatment of suppurative-septic complications in patients with acute appendicitis].
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Appendicitis; Combined Modality Therapy; Dimethyl Sul | 1993 |
Therapeutic effect of dimethyl sulfoxide on ICAM-1 gene expression and activation of NF-kappaB and AP-1 in septic rats.
Topics: Animals; Antioxidants; Cecum; Cell Nucleus; Dimethyl Sulfoxide; Disease Models, Animal; Gene Express | 2001 |