serine has been researched along with Sepsis in 9 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects of insulin receptor substrate (IRS)-1 and its serine (Ser)(307) phosphorylation and tyrosine (Tyr) phosphorylation on insulin resistance in skeletal muscle cells in the state of sepsis." | 7.73 | [Effects of insulin receptor substrate-1 and its serine phosphorylation and tyrosine phosphorylation on insulin resistance in skeletal muscle cells in the state of sepsis: experiment with rats]. ( Li, JS; Li, N; Li, WQ; Wang, XD; Yan, XW, 2006) |
| " Intraperitoneal injection of D-serine obviously limited the lipopolysaccharide-induced changes, including the impairment of learning and memory, the loss of NMDA receptor subunits, robust neuroinflammation, the levels of ROS stress and the decrease of p-CREB in the hippocampus of mice." | 3.85 | Sepsis-induced selective loss of NMDA receptors modulates hippocampal neuropathology in surviving septic mice. ( Ai, S; Le, Y; Ouyang, W; Tong, J; Wang, X; Zhang, S, 2017) |
| "To investigate the effects of insulin receptor substrate (IRS)-1 and its serine (Ser)(307) phosphorylation and tyrosine (Tyr) phosphorylation on insulin resistance in skeletal muscle cells in the state of sepsis." | 3.73 | [Effects of insulin receptor substrate-1 and its serine phosphorylation and tyrosine phosphorylation on insulin resistance in skeletal muscle cells in the state of sepsis: experiment with rats]. ( Li, JS; Li, N; Li, WQ; Wang, XD; Yan, XW, 2006) |
| " In this study, we demonstrate that sepsis induces insulin resistance and that pretreatment with aspirin inhibits sepsis-induced insulin resistance." | 3.72 | Aspirin inhibits serine phosphorylation of IRS-1 in muscle and adipose tissue of septic rats. ( Barreiro, GC; Caliseo, CT; Carvalheira, JB; Fugiwara, FY; Prada, PO; Prattali, RR; Saad, MJ; Ueno, M; Velloso, LA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, S | 1 |
| Wang, X | 1 |
| Ai, S | 1 |
| Ouyang, W | 1 |
| Le, Y | 1 |
| Tong, J | 1 |
| Rodriguez, AE | 1 |
| Ducker, GS | 1 |
| Billingham, LK | 1 |
| Martinez, CA | 1 |
| Mainolfi, N | 1 |
| Suri, V | 1 |
| Friedman, A | 1 |
| Manfredi, MG | 1 |
| Weinberg, SE | 1 |
| Rabinowitz, JD | 1 |
| Chandel, NS | 1 |
| Kwok, W | 1 |
| Clemens, MG | 1 |
| Wang, GQ | 1 |
| Tang, T | 1 |
| Wang, ZS | 1 |
| Liu, YY | 1 |
| Wang, L | 1 |
| Luo, PF | 1 |
| Xia, ZF | 1 |
| Gao, JP | 1 |
| Huang, M | 1 |
| Li, N | 2 |
| Wang, PF | 1 |
| Chen, HL | 1 |
| Xu, QP | 1 |
| Barreiro, GC | 1 |
| Prattali, RR | 1 |
| Caliseo, CT | 1 |
| Fugiwara, FY | 1 |
| Ueno, M | 1 |
| Prada, PO | 1 |
| Velloso, LA | 1 |
| Saad, MJ | 1 |
| Carvalheira, JB | 1 |
| Finigan, JH | 1 |
| Dudek, SM | 1 |
| Singleton, PA | 1 |
| Chiang, ET | 1 |
| Jacobson, JR | 1 |
| Camp, SM | 1 |
| Ye, SQ | 1 |
| Garcia, JG | 1 |
| Yan, XW | 1 |
| Li, WQ | 1 |
| Wang, XD | 1 |
| Li, JS | 1 |
| Aumont, P | 1 |
| Enard, C | 1 |
| Expert, D | 1 |
| Pieddeloup, C | 1 |
| Tancrède, C | 1 |
| Andremont, A | 1 |
9 other studies available for serine and Sepsis
| Article | Year |
|---|---|
Sepsis-induced selective loss of NMDA receptors modulates hippocampal neuropathology in surviving septic mice.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Hippocampus; Inflammation; Lipopolysaccharides | 2017 |
Serine Metabolism Supports Macrophage IL-1β Production.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Female; Interleukin-1beta; Lipopolysaccharides; Ma | 2019 |
Rho-kinase activation contributes to Lps-induced impairment of endothelial nitric oxide synthase activation by endothelin-1 in cultured hepatic sinusoidal endothelial cells.
Topics: Actins; Amides; Animals; Caveolin 1; Cells, Cultured; Cofilin 1; Endothelial Cells; Endothelin-1; En | 2014 |
Overexpression of Hypo-Phosphorylated IκBβ at Ser313 Protects the Heart against Sepsis.
Topics: Animals; Apoptosis; Autophagy; Cathepsin L; Cytokines; Gene Expression; Heart; I-kappa B Proteins; M | 2016 |
Efficacy of a novel endotoxin adsorber polyvinylidene fluoride fiber immobilized with (L)-serine ligand on septic pigs.
Topics: Adsorption; Animals; Endotoxins; Hemoperfusion; Interleukin-6; Ligands; Lipopolysaccharides; Male; O | 2011 |
Aspirin inhibits serine phosphorylation of IRS-1 in muscle and adipose tissue of septic rats.
Topics: Adipose Tissue; Animals; Aspirin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mus | 2004 |
Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation.
Topics: Actins; Blood Coagulation Factors; Cells, Cultured; Cytoskeleton; Dose-Response Relationship, Drug; | 2005 |
[Effects of insulin receptor substrate-1 and its serine phosphorylation and tyrosine phosphorylation on insulin resistance in skeletal muscle cells in the state of sepsis: experiment with rats].
Topics: Adaptor Proteins, Signal Transducing; Animals; Blood Glucose; Insulin Receptor Substrate Proteins; I | 2006 |
Production of haemolysin, aerobactin and enterobactin by strains of Escherichia coli causing bacteraemia in cancer patients, and their resistance to human serum.
Topics: Antibodies, Bacterial; Enterobactin; Escherichia coli; Hemolysin Proteins; Hydroxamic Acids; Neoplas | 1989 |