Compounds > tamarixetin
Page last updated: 2024-08-01 10:42:12

tamarixetin

Description

tamarixetin: isolated from Costsus spicatus [MeSH]

tamarixetin : A monomethoxyflavone that is quercetin methylated at position O-4'. Isolated from Cyperus teneriffae. [CHeBI]

Cross-References

ID SourceID
PubMed CID5281699
CHEMBL ID226034
SCHEMBL ID892776
CHEBI ID67492
MeSH IDM0496365

Synonyms (45)

Synonym
unii-73wra8z8m8
73wra8z8m8 ,
3-o-alpha-l-rhamnopyranosyl-1-2-beta-d-glucopyranoside
3-o-rhamnopyranosyl-1-2-glucopyranoside
4h-1-benzopyran-4-one, 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-
flavone, 4'-methoxy-3,3',5,7-tetrahydroxy-
4'-methoxy-3,3',5,7-tetrahydroxy-flavone
einecs 210-050-7
flavone, 3,3',5,7-tetrahydroxy-4'-methoxy-
4'-o-methylquercetin
4'-methoxyquercetin
quercetin, 4'-methyl ether
4'-methylquercetin
brn 0324993
3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone
603-61-2
tamarixetin
quercetin 4'-methyl ether
chebi:67492 ,
CHEMBL226034 ,
4'-o-methyl quercetin
3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4h-1-benzopyran-4-one
LMPK12110606
3,3',5,7-tetrahydroxy-4'-methoxyflavone
3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one
bdbm50325674
3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4h-chromen-4-one
4'-methoxy-3,3',5,7-tetrahydroxyflavone
FT-0603487
SCHEMBL892776
mfcd00017308
AKOS024287252
AC-34261
4'-methoxy-3,5,7,3'-tetrahydroflavone
quercetin-4'-methylether
FPLMIPQZHHQWHN-UHFFFAOYSA-N
DTXSID00209056 ,
HY-N1181
Q15427839
3,3,5,7-tetrahydroxy-4-methoxyflavone
CS-0016472
3,5,7-trihydroxy-2-(3-hydroxy-4-methoxy-phenyl)chromen-4-one
AS-78314
E80555
dtxcid20131547

Roles (2)

RoleDescription
metaboliteAny intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
antioxidantA substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.

Drug Classes (3)

ClassDescription
7-hydroxyflavonolAny flavonol carrying a 7-hydroxy substituent.
monomethoxyflavoneAny methoxyflavone with a single methoxy substituent.
tetrahydroxyflavoneAny hydroxyflavone carrying four hydroxy substituents.

Protein Targets (5)

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Cytochrome P450 1A1Homo sapiens (human)IC500.1200AID502474
Cytochrome P450 1A2Homo sapiens (human)IC501.2150AID502473
Cytochrome P450 1B1Homo sapiens (human)IC500.0200AID502475
Dihydroorotate dehydrogenase Leishmania majorIC5096.8500AID1417094
Aurora kinase BHomo sapiens (human)IC507.3900AID1801097

Bioassays (192)

Assay IDTitleYearJournalArticle
AID1870067Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as inhibition of bacteria-mediated hemolytic activity on rabbit erythrocytes at 128 ug/ml incubated for 30 mins by hemolysis assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1870061Inhibition of pvl gene transcription level in methicillin-resistant Staphylococcus aureus USA300 at 64 ug/ml by qPCR analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1188615Anticancer activity against human H1299 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1355171Inhibition of Escherichia coli DH5alpha infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-6 secretion at 25 uM pretreated for 30 mins followed by Escherichia coli DH5alpha infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355139Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-6 secretion up to 25 uM pretreated for 30 mins followed by LPS-challenge measured after 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID400608Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression after 18 hrs1996Journal of natural products, Mar, Volume: 59, Issue:3
ISSN: 0163-3864		Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.
AID1870082Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 infected in C57BL/6J mouse pneumonia model assessed as reduction in IL-6 level in lung at 100 mg/Kg, sc administered every 12 hrs measured after 48 hrs by ELISA2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355138Cytotoxicity against C57BL/6 mouse BMDC assessed as effect on cell viability up to 100 uM after 24 hrs by luminescence assay2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1188619Anticancer activity against human LOXIMVI cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID353599Inhibition of CAMK2 assessed as level of ATP utilized by luciferase-based bioluminescence assay2009Journal of medicinal chemistry, Apr-09, Volume: 52, Issue:7
ISSN: 1520-4804		Inhibition of heat shock induction of heat shock protein 70 and enhancement of heat shock protein 27 phosphorylation by quercetin derivatives.
AID1355156Inhibition of LPS-induced TLR4 activation in C57BL/6 mouse BMDC assessed as reduction in ERK phosphorylation at 25 uM pretreated for 30 mins followed by LPS-challenge measured after 15 to 90 mins by Western blot analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870078Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 infected in C57BL/6J mouse pneumonia model assessed as reduction in bacterial load in lung at 100 mg/Kg, sc administered every 12 hrs measured after 48 hrs in presence of ce2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1188622Anticancer activity against human HeLa cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1870056Cytotoxicity against human HepG2 cells at 64 ug/ml by MTT assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355186Inhibition of Escherichia coli K1 infection-induced immune response in C57BL/6 mouse BMDC assessed as increase in IL10 secretion at 25 uM pretreated for 60 to 120 mins followed by Escherichia coli K1 infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID666771Inhibition of thrombin in New Zealand rabbit plasma assessed as fibrinogen level at 100 uM by coagulometry2012European journal of medicinal chemistry, Aug, Volume: 54ISSN: 1768-3254Metabolism-based synthesis, biologic evaluation and SARs analysis of O-methylated analogs of quercetin as thrombin inhibitors.
AID1355142Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as increase in IL10 secretion up to 25 uM pretreated for 30 mins followed by LPS-challenge measured after 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID502474Inhibition of human CYP1A1 by EROD assay2010Bioorganic & medicinal chemistry, Sep-01, Volume: 18, Issue:17
ISSN: 1464-3391		Selective inhibition of methoxyflavonoids on human CYP1B1 activity.
AID1870081Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 infected in C57BL/6J mouse pneumonia model assessed as reduction in IFN-gamma level in lung at 100 mg/Kg, sc administered every 12 hrs measured after 48 hrs by ELISA2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355183Inhibition of Escherichia coli K1 infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-6 secretion at 25 uM pretreated for 60 to 120 mins followed by Escherichia coli K1 infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870083Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 infected in C57BL/6J mouse pneumonia model assessed as reduction in TNF-alpha level in lung at 100 mg/Kg, sc administered every 12 hrs measured after 48 hrs by ELISA2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1417124Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C2C4 trypomastigotes infected in rat skeletal myoblasts L-6 cells after 96 hrs by CPRG/Nonidet reagent based spectrophotometric method2018European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
AID1870051Inhibition of methicillin-resistant Staphylococcus aureus USA300 ClpP using Suc-LY-AMC as fluorescent substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRET assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1188610Anticancer activity against human NCI-H1792 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1154005Cytotoxicity against mouse B16F0 cells assessed as cell viability at 6.25 uM after 72 hrs by MTT assay2014Bioorganic & medicinal chemistry, Jul-01, Volume: 22, Issue:13
ISSN: 1464-3391		Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK.
AID1264957Cytotoxicity against human MSC assessed as cell viability at 5 uM treated for 6 days measured on day 7 by alamar blue assay (Rvb = 96 to 101%)2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1870093Inhibition of methicillin-resistant Staphylococcus aureus USA300 ClpP I84A mutant using Suc-LY-AMC as fluorescent substrate at 64 ug/ml preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRET assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355161Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as increase in survival rate at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured over 72 hrs relative to control2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355141Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-12p70 secretion up to 25 uM pretreated for 30 mins followed by LPS-challenge measured after 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1188616Anticancer activity against human 292G cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1355153Inhibition of LPS-induced TLR4 activation in C57BL/6 mouse BMDC assessed as reduction in Akt phosphorylation at 25 uM pretreated for 30 mins followed by LPS-challenge measured after 15 to 90 mins by Western blot analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355178Inhibition of Escherichia coli DH5alpha infection-induced immune response in C57BL/6 mouse BMDC assessed as increase in IL10 secretion at 25 uM pretreated for 60 to 120 mins followed by Escherichia coli DH5alpha infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355150Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as increase in IL10 secretion at 25 uM treated 6 hrs post LPS-challenge measured after 60 to 120 mins by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355169Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as reduction in serum ALT level at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 12 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1634853Antitubercular activity against XDR Mycobacterium tuberculosis X59 incubated for 1 to 9 days by inverted microscopic analysis2016Journal of natural products, Apr-22, Volume: 79, Issue:4
ISSN: 1520-6025		Antituberculosis Activity of a Naturally Occurring Flavonoid, Isorhamnetin.
AID1355165Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as increase in serum IL10 level at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 2 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355147Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-6 secretion at 25 uM treated 6 hrs post LPS-challenge measured after 60 to 120 mins by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355158Increase in microRNA187 expression in LPS-induced C57BL/6 mouse BMDC at 25 uM pretreated for 30 mins followed by LPS-challenge measured after 6 hrs by qRT-PCR analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1153997Intracellular melanogenesis-stimulating activity in mouse B16F0 cells at 6.25 uM after 72 hrs by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Jul-01, Volume: 22, Issue:13
ISSN: 1464-3391		Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK.
AID697853Inhibition of horse BChE at 2 mg/ml by Ellman's method2012Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22
ISSN: 1464-3391		Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
AID1355184Inhibition of Escherichia coli K1 infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in TNFalpha secretion at 25 uM pretreated for 60 to 120 mins followed by Escherichia coli K1 infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355193Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as reduction in serum ALT level at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 2 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355194Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as reduction in serum blood urea nitrogen level at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 2 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1162595Inhibition of PMA-stimulated NF-kappaB signaling (unknown origin) expressed in MDA-MB-231 cells at 5 uM incubated for 16 hrs by luciferase reporter gene assay2014Bioorganic & medicinal chemistry letters, Oct-01, Volume: 24, Issue:19
ISSN: 1464-3405		Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells--A SAR study.
AID1355151Inhibition of LPS-induced TLR4 activation in C57BL/6 mouse BMDC assessed as reduction in JNK1 phosphorylation at 25 uM pretreated for 30 mins followed by LPS-challenge measured after 15 to 90 mins by Western blot analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870069Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as neutralization of Hla protein in rabbit RBC at 128 ug/ml preincubated for 30 mins followed by RBC addition and measured after 30 mins by hemolysis assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1870094Inhibition of methicillin-resistant Staphylococcus aureus USA300 ClpP Q82A mutant using Suc-LY-AMC as fluorescent substrate at 64 ug/ml preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRET assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355144Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as reduction in TNFalpha secretion at 25 uM treated 6 hrs post LPS-challenge measured after 30 mins by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870066Inhibition of Hla protein expression in methicillin-resistant Staphylococcus aureus Newman at 4 to 64 ug/ml incubated for overnight by western blot analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1634891Binding affinity to human ERK1 expressed in Escherichia coli BL21 by fluorescence quenching based spectrofluorometric analysis2016Journal of natural products, Apr-22, Volume: 79, Issue:4
ISSN: 1520-6025		Antituberculosis Activity of a Naturally Occurring Flavonoid, Isorhamnetin.
AID1162612Inhibition of NF-kappaB signaling in human MDA-MB-231 cells assessed as reduction in PMA-stimulated MMP9 mRNA expression at 25 uM pre-incubated before PMA stimulation by quantitative RT-PCR method2014Bioorganic & medicinal chemistry letters, Oct-01, Volume: 24, Issue:19
ISSN: 1464-3405		Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells--A SAR study.
AID436267Antiplasmodial activity against chloroquine-susceptible Plasmodium falciparum D62008Journal of natural products, Nov, Volume: 71, Issue:11
ISSN: 1520-6025		Bioactive diterpenes and other constituents of Croton steenkampianus.
AID1355149Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-12p70 secretion at 25 uM treated 6 hrs post LPS-challenge measured after 60 to 120 mins by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355155Inhibition of LPS-induced TLR4 activation in C57BL/6 mouse BMDC assessed as reduction in IkappaBalpha degradation at 25 uM pretreated for 30 mins followed by LPS-challenge measured after 15 to 90 mins by Western blot analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID666768Inhibition of thrombin in New Zealand rabbit plasma assessed as thrombin time at 100 uM after 3 mins by coagulometry2012European journal of medicinal chemistry, Aug, Volume: 54ISSN: 1768-3254Metabolism-based synthesis, biologic evaluation and SARs analysis of O-methylated analogs of quercetin as thrombin inhibitors.
AID1870057Cytotoxicity against human HEK-293T cells at 64 ug/ml by MTT assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355172Inhibition of Escherichia coli DH5alpha infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in TNFalpha secretion at 25 uM pretreated for 30 mins followed by Escherichia coli DH5alpha infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355167Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as reduction in IL6 level in lungs at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 12 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355162Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as reduction in infiltration of immune cells at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 12 hrs by hematoxylin and eosin staining based mic2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1634892Binding affinity to human C-terminally His-tagged p38 expressed in Escherichia coli BL21 by fluorescence quenching based spectrofluorometric analysis2016Journal of natural products, Apr-22, Volume: 79, Issue:4
ISSN: 1520-6025		Antituberculosis Activity of a Naturally Occurring Flavonoid, Isorhamnetin.
AID1355143Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-6 secretion at 25 uM treated 6 hrs post LPS-challenge measured after 30 mins by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870055Cytotoxicity against human A549 cells at 64 ug/ml by MTT assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355188Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as reduction in serum TNFalpha level at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 2 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870092Inhibition of methicillin-resistant Staphylococcus aureus USA300 ClpP K85A mutant using Suc-LY-AMC as fluorescent substrate at 64 ug/ml preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRET assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID502473Inhibition of human CYP1A2 by EROD assay2010Bioorganic & medicinal chemistry, Sep-01, Volume: 18, Issue:17
ISSN: 1464-3391		Selective inhibition of methoxyflavonoids on human CYP1B1 activity.
AID436269Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W22008Journal of natural products, Nov, Volume: 71, Issue:11
ISSN: 1520-6025		Bioactive diterpenes and other constituents of Croton steenkampianus.
AID1355196Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as increase in IL10 producing monocyte/macrophage in splenocyte at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 12 hrs by flow cytometric analy2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1264952Cytotoxicity against human MSC assessed as cell viability at 10 uM measured on day 1 by alamar blue assay (Rvb = 97 to 101%)2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1355192Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as reduction in serum AST level at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 2 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355191Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as reduction in infiltration of immune cells in lungs at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 12 hrs by 2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID353598Inhibition of CK2 assessed as level of ATP utilized by luciferase-based bioluminescence assay2009Journal of medicinal chemistry, Apr-09, Volume: 52, Issue:7
ISSN: 1520-4804		Inhibition of heat shock induction of heat shock protein 70 and enhancement of heat shock protein 27 phosphorylation by quercetin derivatives.
AID1355187Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as increase in survival rate at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured up to 20 hrs relative to control2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870063Inhibition of spa gene transcription level in methicillin-resistant Staphylococcus aureus USA300 at 64 ug/ml by qPCR analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355199Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as reduction in bacterial count in lungs at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 12 hrs2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID436271Cytotoxicity against african green monkey Vero cells by MTT assay2008Journal of natural products, Nov, Volume: 71, Issue:11
ISSN: 1520-6025		Bioactive diterpenes and other constituents of Croton steenkampianus.
AID1870052Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as bacterial growth inhibition at 64 ug/ml incubated for 24 hrs by growth curve assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1264945Induction of osteogenic differentiation in human MSC assessed as increase in ALP activity at 1 uM using p-NPP as substrate after 9 days by colorimetric method relative to control2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1355197Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as increase in IL10 producing Tr1 population in splenocyte at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 12 hrs by flow cytometric analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID502475Inhibition of human CYP1B1 by EROD assay2010Bioorganic & medicinal chemistry, Sep-01, Volume: 18, Issue:17
ISSN: 1464-3391		Selective inhibition of methoxyflavonoids on human CYP1B1 activity.
AID1355179Inhibition of Escherichia coli K1 infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-6 secretion at 25 uM pretreated for 30 mins followed by Escherichia coli K1 infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355201Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as reduction in bacterial count in kidneys at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 12 hrs2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID288326Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNL2007Journal of medicinal chemistry, May-31, Volume: 50, Issue:11
ISSN: 0022-2623		Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening.
AID1355170Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as reduction in serum blood urea nitrogen level at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 12 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870070Inhibition of PVL protein expression in methicillin-resistant Staphylococcus aureus USA300 incubated for overnight by western blot analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1264954Cytotoxicity against human MSC assessed as cell viability at 5 uM treated for 3 days measured on day 4 by alamar blue assay (Rvb = 97 to 100%)2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1417091Inhibition of human DHODH at 100 uM2018European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
AID1634852Antitubercular activity against XDR Mycobacterium tuberculosis X24 incubated for 1 to 9 days by inverted microscopic analysis2016Journal of natural products, Apr-22, Volume: 79, Issue:4
ISSN: 1520-6025		Antituberculosis Activity of a Naturally Occurring Flavonoid, Isorhamnetin.
AID353591Enhancement of HSP27 Ser78 phosphorylation in human HeLa cells at 50 ug/mL treated for 1 hr2009Journal of medicinal chemistry, Apr-09, Volume: 52, Issue:7
ISSN: 1520-4804		Inhibition of heat shock induction of heat shock protein 70 and enhancement of heat shock protein 27 phosphorylation by quercetin derivatives.
AID1870086Synergistic antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 infected in C57BL/6J mouse pneumonia model assessed as reduction in infiltration of inflammatory cells in alveoli at 100 mg/Kg, sc administered every 12 hrs meas2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1188618Anticancer activity against human M4E cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1417093Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells at 100 uM using DHO as substrate measured after 60 secs2018European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
AID616482Antioxidant activity assessed as DPPH free radical scavenging activity2011Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18
ISSN: 1464-3405		Synthesis and antioxygenic activities of seabuckthorn flavone-3-ols and analogs.
AID1870084Synergistic antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 infected in C57BL/6J mouse pneumonia model assessed as lethality at 50 mg/Kg, sc administered every 12 hrs measured after 72 hrs in presence of cefotaxime (Rvb =2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID605939Antiestrogenic activity in human MCF7/BUS cells assessed as inhibition of 17beta-estradiol-induced cell proliferation at 10 uM after 6 days by E-Screen test2011Journal of natural products, May-27, Volume: 74, Issue:5
ISSN: 1520-6025		Benzodihydrofurans from Cyperus teneriffae.
AID1355145Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-12p70 secretion at 25 uM treated 6 hrs post LPS-challenge measured after 30 mins by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1264950Cytotoxicity against human MSC assessed as cell viability at 1 uM measured on day 1 by alamar blue assay (Rvb = 97 to 101%)2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1355163Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as reduction in serum TNFalpha level at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 2 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355152Inhibition of LPS-induced TLR4 activation in C57BL/6 mouse BMDC assessed as reduction in p38 phosphorylation at 25 uM pretreated for 30 mins followed by LPS-challenge measured after 15 to 90 mins by Western blot analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870076Binding affinity to methicillin-resistant Staphylococcus aureus USA300 ClpP assessed as dissociation constant by surface plasmon resonance assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1188611Anticancer activity against human NCI-H1944 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1154004Cytotoxicity against mouse B16F0 cells assessed as cell viability at 12.5 uM after 72 hrs by MTT assay2014Bioorganic & medicinal chemistry, Jul-01, Volume: 22, Issue:13
ISSN: 1464-3391		Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK.
AID1355154Inhibition of LPS-induced TLR4 activation in C57BL/6 mouse BMDC assessed as reduction in COX2 expression at 25 uM pretreated for 30 mins followed by LPS-challenge measured after 15 to 90 mins by Western blot analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1188609Anticancer activity against human H460 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID697852Inhibition of electric eel AChE at 2 mg/ml by Ellman's method2012Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22
ISSN: 1464-3391		Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
AID1870080Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 harboring delta ClpP mutant infected in C57BL/6J mouse pneumonia model assessed as reduction in infiltration of inflammatory cells in alveoli at 100 mg/Kg, sc administered e2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1870074Binding affinity to methicillin-resistant Staphylococcus aureus USA300 ClpP assessed as association rate constant by surface plasmon resonance assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355189Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as reduction in serum IL6 level at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 2 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870088Synergistic antifungal activity against Cmethicillin-resistant Staphylococcus aureus USA300 assessed as fractional inhibitory concentration index at 64 ug/ml in presence of cefotaxime by checker board method2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1264953Cytotoxicity against human MSC assessed as cell viability at 1 uM treated for 3 days measured on day 4 by alamar blue assay (Rvb = 97 to 100%)2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1188620Anticancer activity against human M14 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1634850Antitubercular activity against MDR Mycobacterium tuberculosis M22 incubated for 1 to 9 days by inverted microscopic analysis2016Journal of natural products, Apr-22, Volume: 79, Issue:4
ISSN: 1520-6025		Antituberculosis Activity of a Naturally Occurring Flavonoid, Isorhamnetin.
AID1355204Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as increase in survival rate at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured over 72 hrs relative to control2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1188607Anticancer activity against human A549 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1870085Synergistic antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 infected in C57BL/6J mouse pneumonia model assessed as reduction in bacterial load in lung at 100 mg/Kg, sc administered every 12 hrs measured after 48 hrs in pr2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1870050Inhibition of methicillin-resistant Staphylococcus aureus USA300 ClpP using Suc-LY-AMC as fluorescent substrate at 64 ug/ml preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRET assay relative to control2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1188621Anticancer activity against human SKBR cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID666769Inhibition of thrombin in New Zealand rabbit plasma assessed as prothrombin time at 100 uM by coagulometry2012European journal of medicinal chemistry, Aug, Volume: 54ISSN: 1768-3254Metabolism-based synthesis, biologic evaluation and SARs analysis of O-methylated analogs of quercetin as thrombin inhibitors.
AID436270Antiplasmodial activity against chloroquine-susceptible Plasmodium falciparum D102008Journal of natural products, Nov, Volume: 71, Issue:11
ISSN: 1520-6025		Bioactive diterpenes and other constituents of Croton steenkampianus.
AID1870072Binding affinity to methicillin-resistant Staphylococcus aureus USA300 ClpP assessed as decrease in thermal stability of the protein at 16 to 64 ug/ml by SYPRO orange thermal shift assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1154000Extracellular melanogenesis-stimulating activity in mouse B16F0 cells at 12.5 uM after 72 hrs by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Jul-01, Volume: 22, Issue:13
ISSN: 1464-3391		Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK.
AID1355181Inhibition of Escherichia coli K1 infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-12p70 secretion at 25 uM pretreated for 30 mins followed by Escherichia coli K1 infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870053Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 harboring ClpP delta mutant assessed as bacterial growth inhibition at 64 ug/ml incubated for 24 hrs by growth curve assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1153996Intracellular melanogenesis-stimulating activity in mouse B16F0 cells at 12.5 uM after 72 hrs by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Jul-01, Volume: 22, Issue:13
ISSN: 1464-3391		Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK.
AID1153999Extracellular melanogenesis-stimulating activity in mouse B16F0 cells at 25 uM after 72 hrs by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Jul-01, Volume: 22, Issue:13
ISSN: 1464-3391		Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK.
AID1870060Inhibition of RNAIII gene transcription level in methicillin-resistant Staphylococcus aureus USA300 at 64 ug/ml by qPCR analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1870090Inhibition of methicillin-resistant Staphylococcus aureus USA300 ClpP K109A mutant using Suc-LY-AMC as fluorescent substrate at 64 ug/ml preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRET assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID436268Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum Dd22008Journal of natural products, Nov, Volume: 71, Issue:11
ISSN: 1520-6025		Bioactive diterpenes and other constituents of Croton steenkampianus.
AID1355177Inhibition of Escherichia coli DH5alpha infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-12p70 secretion at 25 uM pretreated for 60 to 120 mins followed by Escherichia coli DH5alpha infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1264948Induction of osteogenic differentiation in human MSC assessed as increase in ALP activity using p-NPP as substrate after 9 days by colorimetric method2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1188617Anticancer activity against human Calu1 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1355176Inhibition of Escherichia coli DH5alpha infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in TNFalpha secretion at 25 uM pretreated for 60 to 120 mins followed by Escherichia coli DH5alpha infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1334868Inhibition of LPS-stimulated nitric oxide production in ddy mouse peritoneal macrophages measured after 20 hrs by Greiss method2017Bioorganic & medicinal chemistry, 01-15, Volume: 25, Issue:2
ISSN: 1464-3391		Structure-activity relationship of the inhibitory effects of flavonoids on nitric oxide production in RAW264.7 cells.
AID1355146Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as increase in IL10 secretion at 25 uM treated 6 hrs post LPS-challenge measured after 30 mins by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870075Binding affinity to methicillin-resistant Staphylococcus aureus USA300 ClpP assessed as dissociation rate constant by surface plasmon resonance assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1264958Cytotoxicity against human MSC assessed as cell viability at 10 uM treated for 6 days measured on day 7 by alamar blue assay (Rvb = 96 to 101%)2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1355148Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as reduction in TNFalpha secretion at 25 uM treated 6 hrs post LPS-challenge measured after 60 to 120 mins by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1417094Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured after 60 secs2018European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
AID1355195Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as increase in IL10 producing dendritic cells in splenocyte at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 12 hrs by flow cytometric analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1264947Induction of osteogenic differentiation in human MSC assessed as increase in ALP activity at 10 uM using p-NPP as substrate after 9 days by colorimetric method relative to control2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1870062Inhibition of PSM-alpha gene transcription level in methicillin-resistant Staphylococcus aureus USA300 at 64 ug/ml by qPCR analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355157Binding affinity to human C-terminal His6-tagged JNK1alpha1 (1 to 364 residues) expressed in Escherichia coli by tryptophan fluorescence quenching assay2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870079Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 infected in C57BL/6J mouse pneumonia model assessed as reduction in infiltration of inflammatory cells in alveoli at 100 mg/Kg, sc administered every 12 hrs measured after 42022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1870058Inhibition of hla gene transcription level in methicillin-resistant Staphylococcus aureus USA300 at 64 ug/ml by qPCR analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355166Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as reduction in TNFalpha level in lungs at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 12 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355200Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as reduction in bacterial count in liver at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 12 hrs2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355173Inhibition of Escherichia coli DH5alpha infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-12p70 secretion at 25 uM pretreated for 30 mins followed by Escherichia coli DH5alpha infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1153995Intracellular melanogenesis-stimulating activity in mouse B16F0 cells at 25 uM after 72 hrs by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Jul-01, Volume: 22, Issue:13
ISSN: 1464-3391		Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK.
AID1870054Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 incubated for 24 hrs by microdilution broth assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1870077Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 harboring delta ClpP mutant infected in C57BL/6J mouse pneumonia model assessed as reduction in mortality rate at 50 mg/Kg, sc administered every 12 hrs measured after 72 hr2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355159Increase in microRNA146a expression in LPS-induced C57BL/6 mouse BMDC at 25 uM pretreated for 30 mins followed by LPS-challenge measured after 6 hrs by qRT-PCR analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1634849Antitubercular activity against Mycobacterium tuberculosis H37Rv P887 incubated for 1 to 9 days by inverted microscopic analysis2016Journal of natural products, Apr-22, Volume: 79, Issue:4
ISSN: 1520-6025		Antituberculosis Activity of a Naturally Occurring Flavonoid, Isorhamnetin.
AID1355140Inhibition of LPS-induced immune response in C57BL/6 mouse BMDC assessed as reduction in TNFalpha secretion up to 25 uM pretreated for 30 mins followed by LPS-challenge measured after 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1634855Lipophilicity, logP of the compound2016Journal of natural products, Apr-22, Volume: 79, Issue:4
ISSN: 1520-6025		Antituberculosis Activity of a Naturally Occurring Flavonoid, Isorhamnetin.
AID1355185Inhibition of Escherichia coli K1 infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-12p70 secretion at 25 uM pretreated for 60 to 120 mins followed by Escherichia coli K1 infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355164Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as reduction in serum IL6 level at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 2 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1634851Antitubercular activity against MDR Mycobacterium tuberculosis X23 incubated for 1 to 9 days by inverted microscopic analysis2016Journal of natural products, Apr-22, Volume: 79, Issue:4
ISSN: 1520-6025		Antituberculosis Activity of a Naturally Occurring Flavonoid, Isorhamnetin.
AID1154001Extracellular melanogenesis-stimulating activity in mouse B16F0 cells at 6.25 uM after 72 hrs by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Jul-01, Volume: 22, Issue:13
ISSN: 1464-3391		Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK.
AID666770Inhibition of thrombin in New Zealand rabbit plasma assessed as activated partial thromboplastin time at 100 uM after 3 mins by coagulometry2012European journal of medicinal chemistry, Aug, Volume: 54ISSN: 1768-3254Metabolism-based synthesis, biologic evaluation and SARs analysis of O-methylated analogs of quercetin as thrombin inhibitors.
AID1188612Anticancer activity against human H266 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1188608Anticancer activity against human NCI-H157 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1870087Synergistic antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as cefotaxime MIC by checker board method2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355190Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as increase in serum IL10 level at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 2 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870095Inhibition of methicillin-resistant Staphylococcus aureus USA300 ClpP assessed as upregulation of urease production at 64 ug/ml incubated for 4 hr by spectrophotometry2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1417130Antitrypanosomal activity against Trypanosoma brucei rhodesiense STIB 900 trypomastigotes after 72 hrs by Alamar Blue assay2018European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
AID1264946Induction of osteogenic differentiation in human MSC assessed as increase in ALP activity at 5 uM using p-NPP as substrate after 9 days by colorimetric method relative to control2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1162613Inhibition of NF-kappaB signaling in human MDA-MB-231 cells assessed as reduction in PMA-stimulated COX2 mRNA expression at 25 uM pre-incubated before PMA stimulation by quantitative RT-PCR method2014Bioorganic & medicinal chemistry letters, Oct-01, Volume: 24, Issue:19
ISSN: 1464-3405		Discovery of lesser known flavones as inhibitors of NF-κB signaling in MDA-MB-231 breast cancer cells--A SAR study.
AID1264949Cytotoxicity against human MSC assessed as decrease in cell number at 1 to 10 uM after 9 days by methylene blue staining based microscopy relative to control2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1355160Increase in microRNA155 expression in LPS-induced C57BL/6 mouse BMDC at 25 uM pretreated for 30 mins followed by LPS-challenge measured after 6 hrs by qRT-PCR analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870073Binding affinity to methicillin-resistant Staphylococcus aureus USA300 ClpP assessed as change in thermal stability by measuring protein deposition at 64 ug/ml by measured after 1 hr by cellular thermal shift assay (Rvb = 65 degC)2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1870064Inhibition of agrA gene transcription level in methicillin-resistant Staphylococcus aureus USA300 at 64 ug/ml by qPCR analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355198Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as increase in IL10 producing B10 population in splenocyte at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 12 hrs by flow cytometric analysis2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870059Inhibition of agr gene transcription level in methicillin-resistant Staphylococcus aureus USA300 at 64 ug/ml by qPCR analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355202Antiseptic activity in Balb/c mouse model of Escherichia coli K1 infection-induced sepsis assessed as reduction in serum endotoxin level at 1 mg/kg, ip pretreated for 1 hr followed by Escherichia coli K1 infection measured after 12 hrs by chromogenic assa2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1417122Antileishmanial activity against Leishmania donovani MHOM/ET/67/L82 amastigotes after 72 hrs by Alamar Blue assay2018European journal of medicinal chemistry, Sep-05, Volume: 157ISSN: 1768-3254Natural products as inhibitors of Leishmania major dihydroorotate dehydrogenase.
AID1188614Anticancer activity against human HOP62 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1323133Antioxidant activity assessed as DPPH free radical scavenging activity at 5 uM after 15 to 60 mins in presence of CuSO4.5H2O2016Journal of natural products, 07-22, Volume: 79, Issue:7
ISSN: 1520-6025		Effects of Functional Groups and Sugar Composition of Quercetin Derivatives on Their Radical Scavenging Properties.
AID1264951Cytotoxicity against human MSC assessed as cell viability at 5 uM measured on day 1 by alamar blue assay (Rvb = 97 to 101%)2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1870091Inhibition of methicillin-resistant Staphylococcus aureus USA300 ClpP A106G mutant using Suc-LY-AMC as fluorescent substrate at 64 ug/ml preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRET assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355175Inhibition of Escherichia coli DH5alpha infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in IL-6 secretion at 25 uM pretreated for 60 to 120 mins followed by Escherichia coli DH5alpha infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870065Inhibition of Hla protein expression in methicillin-resistant Staphylococcus aureus USA300 at 4 to 64 ug/ml incubated for overnight by western blot analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1870089Inhibition of methicillin-resistant Staphylococcus aureus USA300 ClpP R157A mutant using Suc-LY-AMC as fluorescent substrate at 64 ug/ml preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRET assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1870068Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 harboring ClpP delta mutant assessed as inhibition of bacteria-mediated hemolytic activity on rabbit erythrocytes at 128 ug/ml incubated for 30 mins by hemolysis assay2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355180Inhibition of Escherichia coli K1 infection-induced immune response in C57BL/6 mouse BMDC assessed as reduction in TNFalpha secretion at 25 uM pretreated for 30 mins followed by Escherichia coli K1 infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1264955Cytotoxicity against human MSC assessed as cell viability at 10 uM treated for 3 days measured on day 4 by alamar blue assay (Rvb = 97 to 100%)2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1355168Antiinflammatory activity in Balb/c mouse model of LPS-induced endotoxemia assessed as reduction in serum AST level at 1 mg/kg, ip pretreated for 1 hr followed by LPS-challenge measured after 12 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1870071Inhibition of PVL protein expression in methicillin-resistant Staphylococcus aureus Newman incubated for overnight by western blot analysis2022Journal of natural products, 08-26, Volume: 85, Issue:8
ISSN: 1520-6025		Tamarixetin Attenuated the Virulence of
AID1355182Inhibition of Escherichia coli K1 infection-induced immune response in C57BL/6 mouse BMDC assessed as increase in IL10 secretion at 25 uM pretreated for 30 mins followed by Escherichia coli K1 infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1355174Inhibition of Escherichia coli DH5alpha infection-induced immune response in C57BL/6 mouse BMDC assessed as increase in IL10 secretion at 25 uM pretreated for 30 mins followed by Escherichia coli DH5alpha infection for 6 hrs by ELISA2018Journal of natural products, 06-22, Volume: 81, Issue:6
ISSN: 1520-6025		Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production.
AID1264956Cytotoxicity against human MSC assessed as cell viability at 1 uM treated for 6 days measured on day 7 by alamar blue assay (Rvb = 96 to 101%)2015Journal of natural products, Nov-25, Volume: 78, Issue:11
ISSN: 1520-6025		Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
AID1188613Anticancer activity against human NCI-H522 cells by HTS assay2014Bioorganic & medicinal chemistry letters, Sep-15, Volume: 24, Issue:18
ISSN: 1464-3405		Synthesis, biological evaluation and SAR analysis of O-alkylated analogs of quercetin for anticancer.
AID1154003Cytotoxicity against mouse B16F0 cells assessed as cell viability at 25 uM after 72 hrs by MTT assay2014Bioorganic & medicinal chemistry, Jul-01, Volume: 22, Issue:13
ISSN: 1464-3391		Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK.
AID1801097Aurora B Kinase Assay from Article 10.1111/cbdd.12445: \\Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationships.\\2015Chemical biology & drug design, May, Volume: 85, Issue:5
ISSN: 1747-0285		Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationships.

Research

Studies (56)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (1.79)18.2507
2000's11 (19.64)29.6817
2010's35 (62.50)24.3611
2020's9 (16.07)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials7 (12.07%)5.53%
Reviews1 (1.72%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other50 (86.21%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
6-prenylchrysin
0
7-hydroxyflavonol;
dihydroxyflavone		00low000000
quercetin
0
7-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger		00low000000
herbacetin
0
7-hydroxyflavonol;
pentahydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antilipemic drug;
antineoplastic agent;
apoptosis inducer;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 4.1.1.17 (ornithine decarboxylase) inhibitor;
plant metabolite		00low000000
gossypetin
0
7-hydroxyflavonol;
hexahydroxyflavone		plant metabolite00low000000
kaempferol
0
7-hydroxyflavonol;
flavonols;
tetrahydroxyflavone		antibacterial agent;
geroprotector;
human blood serum metabolite;
human urinary metabolite;
human xenobiotic metabolite;
plant metabolite		00low000000
azaleatin
0
7-hydroxyflavonol;
monomethoxyflavone;
tetrahydroxyflavone		plant metabolite00low000000
chrysin
0
7-hydroxyflavonol;
dihydroxyflavone		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
EC 2.7.11.18 (myosin-light-chain kinase) inhibitor;
hepatoprotective agent;
plant metabolite		00low000000
datiscetin
0
7-hydroxyflavonol;
tetrahydroxyflavone		00low000000
fisetin
0
3'-hydroxyflavonoid;
7-hydroxyflavonol;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
metabolite;
plant metabolite		00low000000
galangin
0
7-hydroxyflavonol;
trihydroxyflavone		antimicrobial agent;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
plant metabolite		00low000000
gossypin
0
7-hydroxyflavonol;
glycosyloxyflavone;
monosaccharide derivative;
pentahydroxyflavone		neuroprotective agent;
plant metabolite		00low000000
3-methylquercetin
0
7-hydroxyflavonol;
monomethoxyflavone;
tetrahydroxyflavone		anticoagulant;
EC 1.14.18.1 (tyrosinase) inhibitor;
metabolite		00low000000
kaempferide
0
7-hydroxyflavonol;
monomethoxyflavone;
trihydroxyflavone		antihypertensive agent;
metabolite		00low000000
morin
0
7-hydroxyflavonol;
pentahydroxyflavone		angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent		00low000000
myricetin
0
7-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite		00low000000
robinetin
0
7-hydroxyflavonol;
pentahydroxyflavone		plant metabolite00low000000
syringetin
0
3',5'-dimethoxyflavone;
3'-methoxyflavones;
7-hydroxyflavonol;
dimethoxyflavone;
tetrahydroxyflavone		metabolite;
platelet aggregation inhibitor		00low000000
pd 98059
0
aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector		00low000000
pedalitin
0
monomethoxyflavone;
tetrahydroxyflavone		EC 1.17.3.2 (xanthine oxidase) inhibitor;
metabolite		00low000000
swertisin
0
dihydroxyflavone;
flavone C-glycoside;
monomethoxyflavone;
monosaccharide derivative;
polyphenol		adenosine A1 receptor antagonist;
anti-inflammatory agent;
antioxidant;
hypoglycemic agent;
plant metabolite		00low000000
spinosin
0
dihydroxyflavone;
flavone C-glycoside;
monomethoxyflavone		anxiolytic drug;
plant metabolite		00low000000
sideroxylin
0
dihydroxyflavone;
monomethoxyflavone		plant metabolite00low000000
wogonoside
0
beta-D-glucosiduronic acid;
glycosyloxyflavone;
monohydroxyflavone;
monomethoxyflavone;
monosaccharide derivative		00low000000
acacetin
0
dihydroxyflavone;
monomethoxyflavone		anticonvulsant;
plant metabolite		00low000000
chrysoeriol
0
monomethoxyflavone;
trihydroxyflavone		antineoplastic agent;
antioxidant;
metabolite		00low000000
quercetin 3-o-methyl ether
0
monomethoxyflavone;
tetrahydroxyflavone		antimicrobial agent;
metabolite		00low000000
3-methylkaempferol
0
monomethoxyflavone;
trihydroxyflavone		plant metabolite00low000000
diosmetin
0
3'-hydroxyflavonoid;
monomethoxyflavone;
trihydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
bone density conservation agent;
cardioprotective agent;
plant metabolite;
tropomyosin-related kinase B receptor agonist;
vasodilator agent		00low000000
diosmin
0
dihydroxyflavanone;
disaccharide derivative;
glycosyloxyflavone;
monomethoxyflavone;
rutinoside		anti-inflammatory agent;
antioxidant		00low000000
genkwanin
0
dihydroxyflavone;
monomethoxyflavone		metabolite00low000000
hispidulin
0
monomethoxyflavone;
trihydroxyflavone		anti-inflammatory agent;
anticonvulsant;
antineoplastic agent;
antioxidant;
apoptosis inducer;
plant metabolite		00low000000
patuletin
0
flavonols;
monomethoxyflavone;
pentahydroxyflavone		analgesic;
antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
lipoxygenase inhibitor;
metabolite		00low000000
rhamnetin
0
monomethoxyflavone;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
metabolite		00low000000
wogonin
0
dihydroxyflavone;
monomethoxyflavone		angiogenesis inhibitor;
antineoplastic agent;
cyclooxygenase 2 inhibitor;
plant metabolite		00low000000
tectochrysin
0
monohydroxyflavone;
monomethoxyflavone		antidiarrhoeal drug;
antineoplastic agent;
plant metabolite		00low000000
isorhamnetin-3-o-galactoside
0
beta-D-galactoside;
glycosyloxyflavone;
monomethoxyflavone;
monosaccharide derivative;
trihydroxyflavone		metabolite00low000000
isorhamnetin 3-o-glucoside
0
beta-D-glucoside;
glycosyloxyflavone;
monomethoxyflavone;
monosaccharide derivative;
trihydroxyflavone		metabolite00low000000
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one
0
dihydroxyflavone;
monomethoxyflavone		antineoplastic agent;
EC 1.14.13.39 (nitric oxide synthase) inhibitor		00low000000
kaempferol-7-methyl ether
0
flavonols;
monomethoxyflavone;
trihydroxyflavone		plant metabolite00low000000
artocarpin lectin
0
monomethoxyflavone;
trihydroxyflavone		antineoplastic agent;
metabolite		00low000000
narcissin flavonol
0
disaccharide derivative;
glycosyloxyflavone;
monomethoxyflavone;
trihydroxyflavone		00low000000
oroxylin a-7-o-glucuronide
0
beta-D-glucosiduronic acid;
glycosyloxyflavone;
monohydroxyflavone;
monomethoxyflavone;
monosaccharide derivative		plant metabolite00low000000
homoorientin
0
flavone C-glycoside;
tetrahydroxyflavone		antineoplastic agent;
radical scavenger		00low000000
luteolin
0
3'-hydroxyflavonoid;
tetrahydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
c-Jun N-terminal kinase inhibitor;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
immunomodulator;
nephroprotective agent;
plant metabolite;
radical scavenger;
vascular endothelial growth factor receptor antagonist		00low000000
quercitrin
0
alpha-L-rhamnoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		antileishmanial agent;
antioxidant;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite		00low000000
quercetin 3-o-glucopyranoside
0
beta-D-glucoside;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antineoplastic agent;
antioxidant;
antipruritic drug;
bone density conservation agent;
geroprotector;
histamine antagonist;
osteogenesis regulator;
plant metabolite		00low000000
rutin
0
disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone		antioxidant;
metabolite		00low000000
axillarin
0
dimethoxyflavone;
tetrahydroxyflavone		plant metabolite00low000000
hyperoside
0
beta-D-galactoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		hepatoprotective agent;
plant metabolite		00low000000
isoscutellarein
0
tetrahydroxyflavonemetabolite00low000000
kuwanon g
0
resorcinols;
tetrahydroxyflavone		anti-inflammatory agent;
plant metabolite		00low000000
kuwanon h
0
resorcinols;
tetrahydroxyflavone		plant metabolite00low000000
orientin
0
3'-hydroxyflavonoid;
C-glycosyl compound;
tetrahydroxyflavone		antioxidant;
metabolite		00low000000
scutellarein
0
tetrahydroxyflavonemetabolite00low000000
quercimeritrin
0
beta-D-glucoside;
flavonols;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antioxidant;
metabolite		00low000000
quercetin-3-o-sophoroside
0
sophoroside;
tetrahydroxyflavone		antioxidant;
plant metabolite		00low000000
cudraflavone c
0
tetrahydroxyflavoneantibacterial agent;
antineoplastic agent;
plant metabolite		00low000000
quercetin 3-o-gentiobioside
0
disaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		Brassica napus metabolite00low000000
spiraeoside
0
beta-D-glucoside;
flavonols;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antineoplastic agent;
antioxidant;
plant metabolite		00low000000
quercetin 3-sambubioside
0
disaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antioxidant;
plant metabolite		00low000000
avicularin
0
alpha-L-arabinofuranoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		hepatoprotective agent;
plant metabolite		00low000000
quercetin 7-rhamnoside
0
alpha-L-rhamnoside;
flavonols;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		metabolite00low000000
maysin
0
disaccharide derivative;
flavone C-glycoside;
secondary alpha-hydroxy ketone;
tetrahydroxyflavone		insecticide;
neuroprotective agent;
plant metabolite		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
alpha-hydroxyglutarate
0
2-hydroxydicarboxylic acid;
dicarboxylic fatty acid		metabolite;
mouse metabolite		00low000000
alpha-isopropylmalate
0
2-hydroxy carboxylic acid;
3-hydroxy carboxylic acid;
dicarboxylic acid		metabolite00low000000
acetoacetic acid
0
3-oxo fatty acid;
ketone body		metabolite00low000000
3-hydroxybenzyl alcohol
0
hydroxybenzyl alcohol;
phenols		metabolite00low000000
n-carbamoyl-beta-alanine
0
beta-alanine derivativemetabolite;
mouse metabolite		00low000000
ethylene glycol
0
ethanediol;
glycol		metabolite;
mouse metabolite;
solvent;
toxin		00low000000
acetoin
0
methyl ketone;
secondary alpha-hydroxy ketone		metabolite00low000000
ammonium hydroxide
0
azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant		00low000000
benzyl alcohol
0
benzyl alcoholsantioxidant;
fragrance;
metabolite;
solvent		00low000000
carbon monoxide
0
carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent		00low000000
formic acid
0
monocarboxylic acidantibacterial agent;
astringent;
metabolite;
protic solvent;
solvent		00low000000
4-hydroxymandelic acid
0
2-hydroxy carboxylic acid;
phenols		metabolite00low000000
aminoethylphosphonic acid
0
phosphonic acids;
primary amino compound;
zwitterion		human metabolite;
metabolite;
mouse metabolite		00low000000
hydrogen sulfide
0
gas molecular entity;
hydracid;
mononuclear parent hydride;
sulfur hydride		Escherichia coli metabolite;
genotoxin;
metabolite;
signalling molecule;
toxin;
vasodilator agent		00low000000
4-aminophenol
0
aminophenolallergen;
metabolite		00low000000
n(1)-acetylspermidine
0
acetylspermidineEscherichia coli metabolite;
metabolite		00low000000
aminocaproic acid
0
amino acid zwitterion;
epsilon-amino acid;
omega-amino fatty acid		antifibrinolytic drug;
hematologic agent;
metabolite		00low000000
dihydrouracil
0
pyrimidoneEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite		00low000000
dihydroxyacetone
0
ketotriose;
primary alpha-hydroxy ketone		antifungal agent;
Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		00low000000
dimethylamine
0
methylamines;
secondary aliphatic amine		metabolite00low000000
glycolic acid
0
2-hydroxy monocarboxylic acid;
primary alcohol		keratolytic drug;
metabolite		00low000000
hydantoin-5-propionic acid
0
imidazolidine-2,4-dione;
monocarboxylic acid		metabolite;
mouse metabolite		00low000000
niacinamide
0
pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor		00low000000
niacin
0
pyridine alkaloid;
pyridinemonocarboxylic acid;
vitamin B3		antidote;
antilipemic drug;
EC 3.5.1.19 (nicotinamidase) inhibitor;
Escherichia coli metabolite;
human urinary metabolite;
metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent		00low000000
orotic acid
0
pyrimidinemonocarboxylic acidEscherichia coli metabolite;
metabolite;
mouse metabolite		00low000000
oxaloacetic acid
0
C4-dicarboxylic acid;
oxo dicarboxylic acid		geroprotector;
metabolite		00low000000
porphobilinogen
0
aralkylamino compound;
dicarboxylic acid;
pyrroles		Escherichia coli metabolite;
metabolite;
mouse metabolite		00low000000
1-propanol
0
propan-1-ols;
short-chain primary fatty alcohol		metabolite;
protic solvent		00low000000
trimethyloxamine
0
tertiary amine oxideEscherichia coli metabolite;
metabolite;
osmolyte		00low000000
6-hydroxymelatonin
0
acetamides;
tryptamines		metabolite;
mouse metabolite		00low000000
n-acetylphenylalanine
0
N-acetyl-amino acid;
phenylalanine derivative		antidepressant;
metabolite		00low000000
n-acetyltryptophan
0
N-acetyl-amino acid;
tryptophan derivative		metabolite00low000000
arecoline
0
enoate ester;
methyl ester;
pyridine alkaloid;
tetrahydropyridine		metabolite;
muscarinic agonist		00low000000
aristolochic acid i
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin		00low000000
berberine
0
alkaloid antibiotic;
berberine alkaloid;
botanical anti-fungal agent;
organic heteropentacyclic compound		antilipemic drug;
antineoplastic agent;
antioxidant;
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor;
EC 1.21.3.3 (reticuline oxidase) inhibitor;
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
hypoglycemic agent;
metabolite;
potassium channel blocker		00low000000
dibutyl phthalate
0
diester;
phthalate ester		EC 3.2.1.20 (alpha-glucosidase) inhibitor;
environmental contaminant;
metabolite;
plasticiser;
teratogenic agent		00low000000
hydroxymethyltolbutamide
0
benzyl alcohols;
sulfonamide;
ureas		metabolite00low000000
methyl salicylate
0
benzoate ester;
methyl ester;
salicylates		flavouring agent;
insect attractant;
metabolite		00low000000
myristicin
0
organic molecular entitymetabolite00low000000
phenmetrazine
0
morpholinesmetabolite;
sympathomimetic agent		00low000000
phenylbutazone
0
pyrazolidinesantirheumatic drug;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug		00low000000
safrole
0
benzodioxolesflavouring agent;
insecticide;
metabolite;
plant metabolite		00low000000
2,2'-thiodiethanol
0
aliphatic sulfide;
diol		antineoplastic agent;
antioxidant;
metabolite;
solvent		00low000000
sorbitol
0
glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent		00low000000
alloxan
0
pyrimidonehyperglycemic agent;
metabolite		00low000000
thymidine
0
pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite		00low000000
glutamine
0
amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite		00low000000
allyl isothiocyanate
0
alkenyl isothiocyanate;
isothiocyanate		antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
lachrymator;
metabolite		00low000000
n-methyltryptamine
0
tryptamine alkaloid;
tryptamines		metabolite00low000000
4-deoxypyridoxine
0
hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine		metabolite00low000000
cycloserine
0
4-amino-1,2-oxazolidin-3-one;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic;
zwitterion		antiinfective agent;
antimetabolite;
antitubercular agent;
metabolite;
NMDA receptor agonist		00low000000
17-alpha-hydroxyprogesterone
0
17alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
tertiary alpha-hydroxy ketone		human metabolite;
metabolite;
mouse metabolite;
progestin		00low000000
mannitol
0
mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent		00low000000
phenacyl bromide
0
acetophenones;
alpha-bromoketone		metabolite00low000000
trichloroacetic acid
0
monocarboxylic acid;
organochlorine compound		carcinogenic agent;
metabolite;
mouse metabolite		00low000000
acrylic acid
0
alpha,beta-unsaturated monocarboxylic acidmetabolite00low000000
n-methylacetamide
0
acetamides;
monocarboxylic acid amide		metabolite00low000000
bis(4-hydroxyphenyl)sulfone
0
bisphenol;
sulfone		endocrine disruptor;
metabolite		00low000000
rotenone
0
organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin		00low000000
7-amino-4-hydroxy-2-naphthalenesulfonic acid
0
aminonaphthalenesulfonic acid;
naphthols		metabolite00low000000
methyl benzoate
0
benzoate ester;
methyl ester		insect attractant;
metabolite		00low000000
2-dichlorobenzene
0
dichlorobenzenehepatotoxic agent;
metabolite		00low000000
2,4-diaminotoluene
0
aminotoluenemetabolite00low000000
4-butyrolactone
0
butan-4-olidemetabolite;
neurotoxin		00low000000
sulfosalicylic acid
0
arenesulfonic acid;
benzoic acids;
phenols		metabolite00low000000
ethyl lactate
0
ethyl ester;
lactate ester;
secondary alcohol		metabolite00low000000
furaldehyde
0
aldehyde;
furans		Maillard reaction product;
metabolite		00low000000
thiophene-2-carboxaldehyde
0
aldehyde;
thiophenes		metabolite00low000000
alpha-resorcylic acid
0
dihydroxybenzoic acid;
resorcinols		metabolite00low000000
methylenebis(chloroaniline)
0
chloroanilinemetabolite00low000000
2-phenylethyl acetate
0
acetate estermetabolite;
Saccharomyces cerevisiae metabolite		00low000000
dibenzyl ether
0
benzyl ethermetabolite00low000000
ethyl propionate
0
propanoate estermetabolite00low000000
citronellal
0
aldehyde;
monoterpenoid		antifungal agent;
metabolite		00low000000
ethyl oenanthate
0
fatty acid ethyl estermetabolite00low000000
ethyl caprylate
0
fatty acid ethyl ester;
octanoate ester		metabolite00low000000
ethyl laurate
0
fatty acid ethyl estermetabolite00low000000
acetic anhydride
0
acyclic carboxylic anhydridemetabolite;
reagent		00low000000
ethyl isovalerate
0
fatty acid ethyl ester;
olefinic compound		metabolite00low000000
n-butyl n-butyrate
0
butyrate estermetabolite00low000000
ethyl decanoate
0
decanoate ester;
fatty acid ethyl ester		metabolite00low000000
methyl octanoate
0
fatty acid methyl ester;
octanoate ester		metabolite00low000000
2-octanone
0
methyl ketonemetabolite00low000000
hexylamine
0
primary aliphatic aminemetabolite00low000000
lauric acid methyl ester
0
dodecanoate ester;
fatty acid methyl ester		metabolite00low000000
octylamine
0
primary aliphatic aminemetabolite00low000000
n-decyl alcohol
0
decanol;
primary alcohol		metabolite;
pheromone;
protic solvent		00low000000
methyl palmitate
0
fatty acid methyl estermetabolite00low000000
maltol
0
4-pyranonesmetabolite00low000000
chloranil
0
1,4-benzoquinones;
organochlorine compound		EC 2.7.1.33 (pantothenate kinase) inhibitor;
metabolite		00low000000
dibenzoylmethane
0
aromatic ketone;
beta-diketone		antimutagen;
antineoplastic agent;
metabolite		00low000000
methyl anthranilate
0
benzoate esterflavouring agent;
metabolite		00low000000
benzyl acetate
0
acetate ester;
benzyl ester		metabolite00low000000
ethyl acetate
0
acetate ester;
ethyl ester;
volatile organic compound		EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor;
metabolite;
polar aprotic solvent;
Saccharomyces cerevisiae metabolite		00low000000
dibenzyl disulfide
0
organic aromatic compound;
organic disulfide		metabolite00low000000
mequinol
0
methoxybenzenes;
phenols		metabolite00low000000
gamma-resorcylic acid
0
dihydroxybenzoic acidmetabolite00low000000
kynuramine
0
kynurenamines;
primary amino compound		metabolite00low000000
5-methylpyrazole-3-carboxylic acid
0
monocarboxylic acid;
pyrazoles		metabolite00low000000
4-trifluoromethylaniline
0
(trifluoromethyl)benzenes;
substituted aniline		metabolite00low000000
methylguanidine
0
guanidinesEC 1.14.13.39 (nitric oxide synthase) inhibitor;
metabolite;
uremic toxin		00low000000
liriodenine
0
alkaloid antibiotic;
cyclic ketone;
organic heteropentacyclic compound;
oxacycle;
oxoaporphine alkaloid		antifungal agent;
antimicrobial agent;
antineoplastic agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
metabolite		00low000000
plumbagin
0
hydroxy-1,4-naphthoquinone;
phenols		anticoagulant;
antineoplastic agent;
immunological adjuvant;
metabolite		00low000000
imperatorin
0
psoralensEC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite		00low000000
osthol
0
botanical anti-fungal agent;
coumarins		metabolite00low000000
Dillapiole
0
benzodioxolesmetabolite00low000000
coumaran
0
1-benzofuransmetabolite00low000000
1,3-propanediol
0
propane-1,3-diolsmetabolite;
protic solvent		00low000000
tridecanedioic acid
0
alpha,omega-dicarboxylic acidmetabolite00low000000
physcione
0
dihydroxyanthraquinoneanti-inflammatory agent;
antibacterial agent;
antifungal agent;
antineoplastic agent;
apoptosis inducer;
hepatoprotective agent;
metabolite		00low000000
apiole
0
benzodioxolesmetabolite00low000000
flavone
0
flavonesmetabolite;
nematicide		00low000000
cetyl palmitate
0
hexadecanoate estermetabolite00low000000
n-amyl butyrate
0
butyrate estermetabolite00low000000
3-aminobutyric acid
0
amino acid zwitterion;
beta-amino acid;
monocarboxylic acid		metabolite00low000000
methyl lactate
0
lactate ester;
methyl ester		metabolite00low000000
paeonol
0
methoxybenzenes;
phenols		metabolite00low000000
2,2-dimethylbutyric acid
0
dimethylbutyric acidmetabolite00low000000
2-chloroacrylic acid
0
alpha,beta-unsaturated monocarboxylic acid;
chlorocarboxylic acid		metabolite00low000000
galactitol
0
hexitolEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite		00low000000
1-methyluracil
0
nucleobase analogue;
pyrimidone		metabolite00low000000
2-pyrrolidone
0
pyrrolidin-2-onesmetabolite;
polar solvent		00low000000
n-ethylacetamide
0
acetamidesmetabolite00low000000
6-methyluracil
0
pyrimidonemetabolite00low000000
3-methylglutaric acid
0
alpha,omega-dicarboxylic acidmetabolite00low000000
amyl acetate
0
acetate estermetabolite00low000000
dibenzothiophene 5-oxide
0
dibenzothiophenesmetabolite00low000000
2-acetamidoethanethiol
0
acetamidesmetabolite00low000000
2-hydroxyquinoxaline
0
hydroxyquinoxalinemetabolite00low000000
3,4-dihydroxyacetophenone
0
acetophenones;
catechols;
dihydroxyacetophenone		metabolite00low000000
methyl hippurate
0
glycine derivative;
methyl ester		metabolite00low000000
isobarbaloin
0
anthracenes;
C-glycosyl compound;
cyclic ketone;
phenols		laxative;
metabolite		00low000000
vincamine
0
alkaloid ester;
hemiaminal;
methyl ester;
organic heteropentacyclic compound;
vinca alkaloid		antihypertensive agent;
metabolite;
vasodilator agent		00low000000
methyl tert-butyl ether
0
etherfuel additive;
metabolite;
non-polar solvent		00low000000
4-octylphenol
0
phenolsmetabolite;
surfactant;
xenoestrogen		00low000000
dronabinol
0
benzochromene;
diterpenoid;
phytocannabinoid;
polyketide		cannabinoid receptor agonist;
epitope;
hallucinogen;
metabolite;
non-narcotic analgesic		00low000000
phenethyl isothiocyanate
0
isothiocyanateantineoplastic agent;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
metabolite		00low000000
2-methoxy-1,4-naphthoquinone
0
1,4-naphthoquinones;
enol ether		antimicrobial agent;
metabolite;
plant metabolite		00low000000
aviprin
0
furanocoumarinmetabolite00low000000
hydroxyphenytoin
0
imidazolidine-2,4-dione;
phenols		metabolite00low000000
squaric acid
0
alicyclic ketone;
carbon oxoacid		metabolite00low000000
methyl methanethiosulfonate
0
sulfonic acid derivative;
thiosulfonate ester		metabolite00low000000
arabinofuranosyluracil
0
N-glycosyl compoundmetabolite00low000000
6-aminonicotinic acid
0
aminonicotinic acid;
aminopyridine;
aromatic amine		metabolite00low000000
mannose
0
D-aldohexose;
D-mannose;
mannopyranose		metabolite00low000000
2,3-hexanedione
0
alpha-diketonemetabolite00low000000
tabersonine
0
alkaloid ester;
methyl ester;
monoterpenoid indole alkaloid;
organic heteropentacyclic compound		antineoplastic agent;
metabolite		00low000000
3,3-dimethylglutarate
0
alpha,omega-dicarboxylic acidmetabolite00low000000
raspberry ketone
0
methyl ketone;
phenols		androgen antagonist;
cosmetic;
flavouring agent;
fragrance;
hepatoprotective agent;
metabolite		00low000000
laurolitsine
0
aporphine alkaloid;
aromatic ether;
phenols		HIV-1 integrase inhibitor;
metabolite		00low000000
helenalin
0
cyclic ketone;
gamma-lactone;
organic heterotricyclic compound;
secondary alcohol;
sesquiterpene lactone		anti-inflammatory agent;
antineoplastic agent;
metabolite;
plant metabolite		00low000000
diethyl malate
0
malate estermetabolite00low000000
carbendazim
0
benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		antifungal agrochemical;
antinematodal drug;
metabolite;
microtubule-destabilising agent		00low000000
glucoheptonate
0
carbohydrate acid;
monocarboxylic acid		metabolite00low000000
deslanoside
0
12beta-hydroxy steroid;
14beta-hydroxy steroid;
cardenolide glycoside;
tetrasaccharide derivative		anti-arrhythmia drug;
cardiotonic drug;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
metabolite		00low000000
streptozocin
0
N-acylglucosamine;
N-nitrosoureas		antimicrobial agent;
antineoplastic agent;
DNA synthesis inhibitor;
metabolite		00low000000
pedalitin
0
monomethoxyflavone;
tetrahydroxyflavone		EC 1.17.3.2 (xanthine oxidase) inhibitor;
metabolite		00low000000
ethyl nonanoate
0
fatty acid ethyl estermetabolite00low000000
ethyl hexanoate
0
fatty acid ethyl ester;
hexanoate ester		metabolite00low000000
butyl acetate
0
acetate estermetabolite00low000000
1,4-dioxane
0
dioxane;
volatile organic compound		carcinogenic agent;
metabolite;
NMR chemical shift reference compound;
non-polar solvent		00low000000
isoamyl acetate
0
acetate estermetabolite;
Saccharomyces cerevisiae metabolite		00low000000
ribostamycin
0
amino cyclitol glycoside;
aminoglycoside antibiotic		antibacterial drug;
antimicrobial agent;
metabolite		00low000000
tramadol
0
2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanoladrenergic uptake inhibitor;
antitussive;
capsaicin receptor antagonist;
delta-opioid receptor agonist;
kappa-opioid receptor agonist;
metabolite;
mu-opioid receptor agonist;
muscarinic antagonist;
nicotinic antagonist;
NMDA receptor antagonist;
opioid analgesic;
serotonergic antagonist;
serotonin uptake inhibitor		00low000000
6-pentylpyrone
0
2-pyranonesmetabolite00low000000
paclitaxel
0
taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent		00low000000
4-methylhistamine
0
aralkylamino compound;
imidazoles		histamine agonist;
metabolite		00low000000
perfosfamide
0
nitrogen mustard;
organochlorine compound;
peroxol;
phosphorodiamide		alkylating agent;
antineoplastic agent;
drug allergen;
immunosuppressive agent;
metabolite		00low000000
castanospermine
0
indolizidine alkaloidanti-HIV-1 agent;
anti-inflammatory agent;
EC 3.2.1.* (glycosidase) inhibitor;
metabolite		00low000000
pravastatin
0
3-hydroxy carboxylic acid;
carbobicyclic compound;
carboxylic ester;
hydroxy monocarboxylic acid;
secondary alcohol;
statin (semi-synthetic)		anticholesteremic drug;
environmental contaminant;
metabolite;
xenobiotic		00low000000
3-methyl-2-butenal
0
enalmetabolite00low000000
ethyl 3-hydroxybutyrate
0
fatty acid ethyl estermetabolite00low000000
4,5-dimethyl-3-hydroxy-2(5h)-furanone
0
butenolidemetabolite00low000000
n-methylnicotinamide
0
pyridinecarboxamidemetabolite00low000000
3-aminoisobutyric acid
0
amino acid zwitterion;
beta-amino acid		metabolite00low000000
platanic acid
0
hydroxy monocarboxylic acid;
methyl ketone;
pentacyclic triterpenoid		anti-HIV agent;
metabolite		00low000000
2'-deoxyuridylic acid
0
deoxyuridine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
metabolite;
mouse metabolite		00low000000
gallocatechol
0
gallocatechinantioxidant;
metabolite;
radical scavenger		00low000000
1-methylinosine
0
inosinesmetabolite00low000000
dihydrobetulinic acid
0
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		anti-HIV agent;
antileishmanial agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
metabolite		00low000000
bergenin
0
trihydroxybenzoic acidmetabolite00low000000
2-methoxyestradiol
0
17beta-hydroxy steroid;
3-hydroxy steroid		angiogenesis modulating agent;
antimitotic;
antineoplastic agent;
human metabolite;
metabolite;
mouse metabolite		00low000000
3'-cmp
0
cytidine 3'-phosphate;
pyrimidine ribonucleoside 3'-monophosphate		Escherichia coli metabolite;
metabolite;
mouse metabolite		00low000000
xanthoxyletin
0
coumarinsmetabolite00low000000
pinocembrin
0
(2S)-flavan-4-one;
dihydroxyflavanone		antineoplastic agent;
antioxidant;
metabolite;
neuroprotective agent;
vasodilator agent		00low000000
orsellinic acid
0
dihydroxybenzoic acid;
resorcinols		fungal metabolite;
marine metabolite;
metabolite		00low000000
isoimperatorin
0
psoralensEC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite		00low000000
rotenolone
0
organic molecular entitymetabolite00low000000
seselin
0
coumarinsmetabolite00low000000
perillene
0
furans;
monoterpenoid		fragrance;
metabolite;
semiochemical		00low000000
glycine methyl ester
0
glycinyl estermetabolite00low000000
hexadecanamide
0
primary fatty amidemetabolite00low000000
benzocyclobutene
0
carbobicyclic compoundmetabolite00low000000
9-methyladenine
0
methyladeninemetabolite00low000000
n'-methyl-2-pyridone-5-carboxamide
0
methylpyridines;
pyridinecarboxamide;
pyridone		metabolite;
mouse metabolite		00low000000
1,3-dimethyluracil
0
pyrimidonemetabolite00low000000
3-methoxysalicylic acid
0
methoxysalicylic acidmetabolite00low000000
1,3-dimethyluric acid
0
oxopurinemetabolite00low000000
leucyltyrosine
0
dipeptidemetabolite00low000000
3-methylxanthine
0
3-methylxanthinemetabolite00low000000
leucyl-glycyl-glycine
0
tripeptidemetabolite00low000000
acetylleucine
0
L-leucine derivative;
N-acetyl-L-amino acid		metabolite00low000000
n-benzoylalanine, (dl-ala)-isomer
0
alanine derivative;
N-acyl-amino acid		metabolite00low000000
dipropylacetamide
0
fatty amidegeroprotector;
metabolite;
teratogenic agent		00low000000
masoprocol
0
nordihydroguaiaretic acidantineoplastic agent;
hypoglycemic agent;
lipoxygenase inhibitor;
metabolite		00low000000
7-methyladenine
0
methyladeninemetabolite00low000000
acetylisoniazid
0
carbohydrazidemetabolite00low000000
illimaquinone
0
monohydroxy-1,4-benzoquinones;
prenylquinone		metabolite00low000000
coptisine
0
alkaloidmetabolite00low000000
betulin
0
diol;
pentacyclic triterpenoid		analgesic;
anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
metabolite		00low000000
narciclasine
0
phenanthridinesmetabolite00low000000
lividomycin
0
lividomycinsmetabolite00low000000
dmp 323
0
diazepanone;
ureas		anti-HIV agent;
metabolite		00low000000
eupolauridine
0
naphthyridine derivativemetabolite00low000000
zaluzanin C
0
gamma-lactone;
guaiane sesquiterpenoid;
organic heterotricyclic compound;
secondary alcohol;
sesquiterpene lactone		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
metabolite		00low000000
2-aminonicotinic acid
0
aminonicotinic acid;
aminopyridine		metabolite00low000000
(-)-catechin
0
catechinmetabolite00low000000
dehydrocostus lactone
0
gamma-lactone;
guaiane sesquiterpenoid;
organic heterotricyclic compound;
sesquiterpene lactone		antimycobacterial drug;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 2 inhibitor;
metabolite;
trypanocidal drug		00low000000
Tormentic acid
0
triterpenoidmetabolite00low000000
pinobanksin
0
secondary alpha-hydroxy ketone;
trihydroxyflavanone		antimutagen;
antioxidant;
metabolite		00low000000
sigmoidin a
0
4'-hydroxyflavanones;
tetrahydroxyflavanone		anti-inflammatory agent;
anti-obesity agent;
antibacterial agent;
metabolite;
radical scavenger		00low000000
xanthosine 5'-triphosphate
0
purine ribonucleoside 5'-monophosphate;
xanthosine 5'-phosphate		Escherichia coli metabolite;
metabolite;
mouse metabolite		00low000000
monotropein
0
beta-D-glucoside;
cyclopentapyran;
iridoid monoterpenoid;
monocarboxylic acid;
monosaccharide derivative		anti-inflammatory agent;
metabolite		00low000000
glycyl-histidyl-lysine
0
tripeptidechelator;
hepatoprotective agent;
metabolite;
vulnerary		00low000000
homoeriodictyol
0
3'-methoxyflavanones;
4'-hydroxyflavanones;
monomethoxyflavanone;
trihydroxyflavanone		flavouring agent;
metabolite		00low000000
arjunolic acid
0
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		antibacterial agent;
antifungal agent;
antioxidant;
metabolite		00low000000
oxazolidin-2-one
0
carbamate ester;
oxazolidinone		metabolite00low000000
monoethyl phthalate
0
ethyl ester;
phthalic acid monoester		metabolite00low000000
methylimidazoleacetic acid
0
imidazoles;
monocarboxylic acid		GABA agonist;
metabolite		00low000000
2-(2-aminoethyl)pyridine
0
aminoalkylpyridine;
primary amine		histamine agonist;
metabolite		00low000000
xanthurenic acid 8-methyl ether
0
aromatic ether;
monohydroxyquinoline;
quinolinemonocarboxylic acid		carcinogenic agent;
metabolite;
mouse metabolite		00low000000
methyl orsellinate
0
hydroxybenzoic acidmetabolite00low000000
2,2-di(4-methacryloxyphenyl)propane
0
bisphenol;
enoate ester		metabolite00low000000
sofosbuvir
0
aminopyrimidine;
aromatic carboxylic acid;
nucleobase analogue;
pyrimidone		metabolite00low000000
3-methyluracil
0
nucleobase analogue;
pyrimidone		metabolite00low000000
1-methylcytosine
0
aminopyrimidine;
methylcytosine;
pyrimidone		metabolite00low000000
leucyl-alanine
0
dipeptidemetabolite00low000000
leucyl-leucyl-leucine
0
tripeptidemetabolite00low000000
3,4-dihydroxyphenylethanol
0
catechols;
primary alcohol		antineoplastic agent;
antioxidant;
metabolite		00low000000
3,7-dimethyluric acid
0
oxopurinemetabolite;
mouse metabolite		00low000000
alanylproline
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
d-biotin-d-sulfoxide
0
biotins;
sulfoxide		metabolite00low000000
biotin sulfone
0
biotins;
sulfone		metabolite00low000000
asperuloside
0
acetate ester;
beta-D-glucoside;
gamma-lactone;
iridoid monoterpenoid;
monosaccharide derivative		metabolite00low000000
primin
0
1,4-benzoquinonesallergen;
antifeedant;
antimicrobial agent;
hapten;
metabolite		00low000000
2-(hydroxymethyl)anthraquinone
0
anthraquinonemetabolite00low000000
tyrosylleucine
0
dipeptidemetabolite00low000000
o-methylserine
0
L-serine derivative;
non-proteinogenic L-alpha-amino acid		metabolite00low000000
cinchonine
0
(8xi)-cinchonan-9-ol;
cinchona alkaloid		metabolite00low000000
aucubin
0
organic molecular entitymetabolite00low000000
catalpol
0
organic molecular entitymetabolite00low000000
3,4-dihydroxyphenylglycol
0
catechols;
tetrol		metabolite;
mouse metabolite		00low000000
2-methylhistamine
0
aralkylamino compound;
imidazoles		histamine agonist;
metabolite		00low000000
2-methylhippuric acid
0
N-acylglycinemetabolite00low000000
taraxerol
0
pentacyclic triterpenoid;
secondary alcohol		metabolite00low000000
alpha-peltatin
0
furonaphthodioxole;
gamma-lactone;
lignan;
organic heterotetracyclic compound;
phenols		antineoplastic agent;
metabolite		00low000000
3-acetyllupeol
0
organic molecular entitymetabolite00low000000
lupenone
0
triterpenoidmetabolite00low000000
glycyltryptophan
0
dipeptidemetabolite00low000000
monocerin
0
hydroxybenzoic acidmetabolite00low000000
propionyl-coenzyme a
0
acyl-CoAEscherichia coli metabolite;
metabolite;
mouse metabolite		00low000000
alpha-hydroxyisocaproic acid
0
2-hydroxy fatty acid;
branched-chain fatty acid		metabolite00low000000
totarol
0
diterpenoidmetabolite00low000000
taraxerone
0
scalarane sesterterpenoidmetabolite00low000000
prunin protein, prunus
0
(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
flavanone 7-O-beta-D-glucoside;
monosaccharide derivative		antibacterial agent;
antilipemic drug;
hypoglycemic agent;
metabolite		00low000000
uvaol
0
triterpenoidmetabolite00low000000
glycyltyrosine
0
dipeptidemetabolite00low000000
glycylleucine
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
alanyltyrosine
0
dipeptidemetabolite00low000000
glycyl-l-phenylalanine
0
dipeptide zwitterion;
dipeptide		human metabolite;
metabolite		00low000000
digoxigenin-mono(digitoxoside)
0
cardenolide glycoside;
digitoxoside;
monosaccharide derivative;
steroid saponin		metabolite00low000000
thiazolidine-4-carboxylic acid, (r)-isomer
0
thiazolidinemonocarboxylic acid;
thioproline		geroprotector;
metabolite		00low000000
5,6-dihydrothymine
0
pyrimidonehuman metabolite;
metabolite;
mouse metabolite		00low000000
dehydroabietic acid
0
abietane diterpenoid;
carbotricyclic compound;
monocarboxylic acid		allergen;
metabolite		00low000000
palmitone
0
dialkyl ketoneanticonvulsant;
metabolite		00low000000
1-methylthymine
0
methylthyminemetabolite00low000000
imidazoleacetic acid
0
imidazoles;
monocarboxylic acid		metabolite;
mouse metabolite		00low000000
1-methylguanosine
0
methylguanosinemetabolite00low000000
alanylphenylalanine
0
dipeptidemetabolite00low000000
murrayanine
0
carbazolesmetabolite00low000000
girinimbine
0
carbazolesmetabolite00low000000
tryptophylglycine
0
dipeptidemetabolite00low000000
canthin-6-one
0
enone;
indole alkaloid;
organic heterotetracyclic compound		antimycobacterial drug;
metabolite		00low000000
glycylaspartic acid
0
dipeptidemetabolite00low000000
4-methylhippuric acid
0
N-acylglycinemetabolite00low000000
delta(9)-tetrahydrocannabinolic acid
0
benzochromene;
diterpenoid;
hydroxy monocarboxylic acid;
phytocannabinoid;
polyketide		anti-inflammatory agent;
biomarker;
metabolite;
neuroprotective agent		00low000000
3-methylhippuric acid
0
N-acylglycinemetabolite00low000000
n-glycylglutamic acid
0
dipeptidemetabolite00low000000
n-caproylglycine
0
N-acylglycinemetabolite00low000000
diosgenin
0
3beta-sterol;
hexacyclic triterpenoid;
sapogenin;
spiroketal		antineoplastic agent;
antiviral agent;
apoptosis inducer;
metabolite		00low000000
s-2-aminoethyl cysteine
0
L-cysteine thioether;
non-proteinogenic L-alpha-amino acid		EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor;
metabolite;
protein synthesis inhibitor		00low000000
4-hydroxycyclophosphamide
0
nitrogen mustard;
organochlorine compound;
phosphorodiamide		alkylating agent;
metabolite		00low000000
alpha-glutamyltryptophan
0
dipeptideangiogenesis modulating agent;
antineoplastic agent;
immunomodulator;
metabolite		00low000000
malabaricone c
0
butanonemetabolite00low000000
loliolide
0
benzofuransmetabolite00low000000
tuberostemonine
0
alkaloidmetabolite00low000000
pyrrole-3-carboxylic acid
0
pyrrolecarboxylic acidmetabolite;
Penicillium metabolite		00low000000
histidylglycine
0
dipeptidemetabolite00low000000
histidinoalanine
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
cinchonidine
0
(8xi)-cinchonan-9-ol;
cinchona alkaloid		metabolite00low000000
quillaic acid
0
aldehyde;
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		anti-inflammatory agent;
metabolite		00low000000
p-methoxy-n-methylphenethylamine
0
aromatic ether;
secondary amino compound		metabolite00low000000
ecgonine methyl ester
0
methyl ester;
tertiary amino compound;
tropane alkaloid		analgesic;
central nervous system depressant;
metabolite;
mouse metabolite;
opioid analgesic;
peripheral nervous system drug		00low000000
n-acetylcytidine
0
acetamides;
cytidines;
secondary carboxamide		metabolite00low000000
4-hydroxydebrisoquin
0
carboxamidine;
isoquinolines;
secondary alcohol		metabolite00low000000
hypotaurine
0
aminosulfinic acid;
zwitterion		human metabolite;
metabolite;
mouse metabolite		00low000000
hc toxin
0
homodetic cyclic peptide;
tetrapeptide		antineoplastic agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
metabolite;
phytotoxin		00low000000
epicatechin gallate
0
catechin;
gallate ester;
polyphenol		EC 3.2.1.1 (alpha-amylase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
metabolite		00low000000
versiconal hemiacetal acetate
0
acetate ester;
anthrafuran;
lactol;
palmitoyl amino acid;
polyphenol		metabolite00low000000
selenodiglutathione
0
glutathione derivative;
thioselenide		Escherichia coli metabolite;
metabolite		00low000000
coprine
0
cyclopropanes;
dicarboxylic acid monoamide;
L-glutamine derivative;
non-proteinogenic L-alpha-amino acid		EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
metabolite;
mycotoxin		00low000000
aristolochic acid ii
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin		00low000000
exp3174
0
biphenylyltetrazole;
imidazoles;
organochlorine compound		metabolite00low000000
ribonolactone
0
butan-4-olide;
ribonolactone		metabolite00low000000
sulfamethoxazole hydroxylamine
0
isoxazoles;
sulfonamide		allergen;
metabolite		00low000000
androsterone glucuronide
0
beta-D-glucosiduronic acid;
steroid glucosiduronic acid		human metabolite;
metabolite;
mouse metabolite		00low000000
tephrosin
0
aromatic ether;
cyclic ketone;
organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
pesticide		00low000000
sapintoxin d
0
phorbol ester;
tertiary alpha-hydroxy ketone		fluorescent probe;
metabolite		00low000000
amarogentin
0
monosaccharide derivative;
secoiridoid glycoside		EC 5.99.1.2 (DNA topoisomerase) inhibitor;
metabolite		00low000000
taraxasterol
0
pentacyclic triterpenoid;
secondary alcohol		anti-inflammatory agent;
metabolite		00low000000
asiatic acid
0
monocarboxylic acid;
pentacyclic triterpenoid;
triol		angiogenesis modulating agent;
metabolite		00low000000
flavoglaucin
0
hydroquinonesmetabolite00low000000
1-(6-hydroxy-2-isopropenyl-1-benzofuran-5-yl)-1-ethanone
0
benzofuransmetabolite00low000000
dioscin
0
hexacyclic triterpenoid;
spiroketal;
spirostanyl glycoside;
trisaccharide derivative		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 1.14.18.1 (tyrosinase) inhibitor;
hepatoprotective agent;
metabolite		00low000000
maculosin
0
dipeptide;
homodetic cyclic peptide;
phenols;
pyrrolopyrazine		metabolite00low000000
n(4)-methylcytosine
0
aminopyrimidine;
methylcytosine;
pyrimidone		metabolite00low000000
n-acetylputrescine
0
N-monoacetylalkane-alpha,omega-diamine;
N-substituted putrescine		metabolite;
mouse metabolite		00low000000
4'-demethylpodophyllotoxin
0
furonaphthodioxole;
organic heterotetracyclic compound;
phenols		metabolite00low000000
lysicamine
0
alkaloid antibiotic;
oxoaporphine alkaloid		metabolite00low000000
celastrol
0
monocarboxylic acid;
pentacyclic triterpenoid		anti-inflammatory drug;
antineoplastic agent;
antioxidant;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Hsp90 inhibitor;
metabolite		00low000000
procyanidin b2
0
biflavonoid;
hydroxyflavan;
polyphenol;
proanthocyanidin		antioxidant;
metabolite		00low000000
aromadedrin
0
4'-hydroxyflavanones;
dihydroflavonols;
secondary alpha-hydroxy ketone;
tetrahydroxyflavanone		metabolite00low000000
3-methylthymine
0
methylthymine;
pyrimidone		metabolite00low000000
tyrosyl-glycyl-glycine
0
tripeptide zwitterion;
tripeptide		metabolite00low000000
cyclic adp-ribose
0
cyclic purine nucleotide;
nucleotide-sugar		metabolite;
ryanodine receptor agonist		00low000000
glycylglutamine
0
dipeptide zwitterion;
dipeptide		metabolite;
protective agent		00low000000
alanylglutamine
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
naadp
0
nicotinic acid dinucleotidecalcium channel agonist;
metabolite;
signalling molecule		00low000000
procyanidin b5
0
biflavonoid;
hydroxyflavan;
polyphenol;
proanthocyanidin		metabolite00low000000
proanthocyanidin a2
0
hydroxyflavan;
proanthocyanidin		angiogenesis modulating agent;
anti-HIV agent;
antioxidant;
metabolite		00low000000
dihydrosanguinarine
0
benzophenanthridine alkaloidantifungal agent;
metabolite		00low000000
tetrahydrocurcumin
0
beta-diketone;
diarylheptanoid;
polyphenol		metabolite00low000000
eriodictyol 7-glucuronide
0
3'-hydroxyflavonoid;
beta-D-glucosiduronic acid		EC 1.1.1.21 (aldehyde reductase) inhibitor;
metabolite		00low000000
beta-lipotropin, gln(9)-
0
catechols;
crown compound;
macrocyclic lactone		bacterial metabolite;
metabolite		00low000000
4-nitrososulfamethoxazole
0
isoxazoles;
nitroso compound;
sulfonamide		allergen;
metabolite		00low000000
protosappanin a
0
catecholsmetabolite00low000000
3,3'-neotrehalosadiamine
0
amino disaccharide;
glycosyl glycoside derivative		antimicrobial agent;
metabolite		00low000000
salvinorin a
0
organic heterotricyclic compound;
organooxygen compound		metabolite;
oneirogen		00low000000
cyanidin
0
5-hydroxyanthocyanidinantioxidant;
metabolite;
neuroprotective agent		00low000000
yakuchinone-a
0
ketone;
monomethoxybenzene;
phenols		antineoplastic agent;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
metabolite		00low000000
marsupsin
0
1-benzofurans;
aromatic ether;
polyphenol		antilipemic drug;
hypoglycemic agent;
metabolite		00low000000
6,6'-bieckol
0
aromatic ether;
oxacycle;
phlorotannin		anti-HIV-1 agent;
metabolite;
radical scavenger		00low000000
3-methylcytosine
0
aminopyrimidine;
methylcytosine;
pyrimidone		metabolite00low000000
eckol
0
phlorotanninantioxidant;
metabolite		00low000000
procyanidin b3
0
biflavonoid;
hydroxyflavan;
polyphenol;
proanthocyanidin		anti-inflammatory agent;
antioxidant;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
metabolite		00low000000
aclacinomycin
0
aminoglycoside;
anthracycline;
deoxy hexoside;
methyl ester;
monosaccharide derivative;
phenols;
polyketide;
tertiary alcohol;
tetracenequinones;
zwitterion		antimicrobial agent;
antineoplastic agent;
metabolite		00low000000
phenylalanylarginine
0
dipeptidemetabolite00low000000
prolylarginine
0
dipeptidemetabolite00low000000
5-methoxytryptophan
0
L-alpha-amino acid zwitterion;
L-tryptophan derivative		metabolite00low000000
phenylalanylglutamate
0
dipeptidemetabolite00low000000
aspartylglycine
0
dipeptidemetabolite00low000000
aspartylglutamate
0
dipeptidemetabolite00low000000
5-hydroxypipecolic acid
0
piperidinemonocarboxylic acidmetabolite00low000000
prolyl-tyrosine
0
dipeptidemetabolite00low000000
histidylproline
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
phenylalanyl-glycyl-glycine
0
tripeptidemetabolite00low000000
leucylarginine
0
dipeptidemetabolite00low000000
pendolmycin
0
indolesmetabolite00low000000
atractylenolide iii
0
naphthofuranmetabolite00low000000
malvidin
0
5-hydroxyanthocyanidinbiological pigment;
metabolite		00low000000
5-hydroxytryptoline
0
beta-carbolinesmetabolite00low000000
perlolyrine
0
organic molecular entitymetabolite00low000000
endocrocin
0
monocarboxylic acid;
phenols;
trihydroxyanthraquinone		metabolite00low000000
sulochrin
0
benzophenones;
carboxylic ester;
phenols		metabolite00low000000
i-677
0
L-serine derivative;
non-proteinogenic L-alpha-amino acid		antimetabolite;
antimicrobial agent;
antineoplastic agent;
metabolite		00low000000
isohomovanillic acid
0
aromatic ether;
phenols;
phenylacetic acids		metabolite00low000000
4-amino-2-methoxypyrimidine
0
aminopyrimidine;
aromatic ether;
methylcytosine		metabolite00low000000
asimilobine
0
aporphine alkaloidmetabolite00low000000
aristolochic acid D
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
nephrotoxin;
toxin		00low000000
leukodopachrome
0
hydroxy monocarboxylic acid;
indoles		metabolite00low000000
ampelopsin
0
dihydromyricetin;
secondary alpha-hydroxy ketone		antineoplastic agent;
antioxidant;
metabolite		00low000000
pinusolide
0
diterpene lactonemetabolite00low000000
2,4,5-trihydroxypentanoic acid gamma-lactone
0
ribonolactonemetabolite00low000000
hydroxysitosterol
0
3beta-hydroxy-Delta(5)-steroid;
7alpha-hydroxy steroid		metabolite;
plant metabolite		00low000000
jolkinolide a
0
diterpene lactonemetabolite00low000000
jolkinolide b
0
diterpene lactonemetabolite00low000000
1-o-hexadecyl-2-lyso-glycero-3-phosphorylcholine
0
1-alkyl-sn-glycero-3-phosphocholine;
lysophosphatidylcholine O-16:0		metabolite00low000000
isovitexin
0
C-glycosyl compound;
trihydroxyflavone		EC 3.2.1.20 (alpha-glucosidase) inhibitor;
metabolite		00low000000
dopamine quinone
0
1,2-benzoquinones;
primary amino compound		metabolite00low000000
platycodin d
0
triterpenoid saponinmetabolite00low000000
frenolicin b
0
benzoisochromanequinone;
p-quinones		metabolite00low000000
4-oxopentanal
0
ketoaldehydemetabolite00low000000
my 12-62c
0
monohydroxyquinoline;
quinolone		antibacterial agent;
iron chelator;
metabolite;
signalling molecule		00low000000
3,4-dihydroxyphenylpyruvic acid
0
2-oxo monocarboxylic acidmetabolite00low000000
proximadiol
0
eudesmane sesquiterpenoidmetabolite00low000000
aristolochic acid c
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin		00low000000
phenylacetyl-coenzyme a
0
acyl-CoAEscherichia coli metabolite;
metabolite;
mouse metabolite		00low000000
taxusin
0
acetate ester;
carbotricyclic compound;
taxane diterpenoid		metabolite00low000000
confertin
0
cyclic ketone;
gamma-lactone;
organic heterotricyclic compound;
pseudoguaianolide		anti-inflammatory agent;
metabolite;
plant metabolite		00low000000
beta-methylcrotonylglycine
0
N-acylglycinemetabolite00low000000
tracheloside
0
glycoside;
lignan		metabolite00low000000
maytenonic acid
0
triterpenoidmetabolite00low000000
procyanidin C1
0
hydroxyflavan;
polyphenol;
proanthocyanidin		anti-inflammatory agent;
antioxidant;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
lipoxygenase inhibitor;
metabolite		00low000000
3-methyleneindolenine
0
indolesmetabolite00low000000
isopulegol
0
p-menthane monoterpenoidmetabolite00low000000
kadsurin
0
tanninmetabolite00low000000
lysylproline
0
dipeptidemetabolite00low000000
5-o-methylembelin
0
enol ether;
monohydroxy-1,4-benzoquinones		antileishmanial agent;
antineoplastic agent;
hepatitis C protease inhibitor;
metabolite		00low000000
dihydrodaidzein
0
hydroxyisoflavanonemetabolite00low000000
4'-o-methylepigallocatechin
0
catechinmetabolite00low000000
corynoline
0
benzophenanthridine alkaloid;
cyclic acetal;
isoquinolines;
organic heterohexacyclic compound;
secondary alcohol		antineoplastic agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
hepatoprotective agent;
metabolite		00low000000
limonin
0
epoxide;
furans;
hexacyclic triterpenoid;
lactone;
limonoid;
organic heterohexacyclic compound		inhibitor;
metabolite;
volatile oil component		00low000000
dichamanetin
0
diarylheptanoidmetabolite00low000000
brevianamide f
0
dipeptide;
indoles;
pyrrolopyrazine		metabolite00low000000
ergolide
0
acetate ester;
cyclic ketone;
gamma-lactone;
organic heterotricyclic compound;
sesquiterpene lactone		anti-inflammatory agent;
antineoplastic agent;
metabolite;
NF-kappaB inhibitor;
plant metabolite		00low000000
4-sulfocatechol
0
dihydroxybenzenesulfonic acidmetabolite00low000000
histidylleucine
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
7-methoxyheptaphylline
0
carbazolesmetabolite00low000000
phenylalanylserine
0
dipeptidemetabolite00low000000
phellamurin
0
4'-hydroxyflavanones;
beta-D-glucoside;
dihydroflavonols;
flavanone glycoside;
monosaccharide derivative;
trihydroxyflavanone		metabolite00low000000
prolylglutamic acid
0
dipeptidemetabolite00low000000
nantenine
0
oxoaporphine alkaloidmetabolite00low000000
hydrastine
0
isoquinolinesmetabolite00low000000
butyrylcarnitine
0
O-butanoylcarnitine;
saturated fatty acyl-L-carnitine		metabolite00low000000
2-hydroxyestradiol
0
17beta-hydroxy steroid;
2-hydroxy steroid		carcinogenic agent;
human metabolite;
metabolite;
mouse metabolite;
prodrug		00low000000
aromaticin
0
cyclic ketone;
gamma-lactone;
organic heterotricyclic compound;
sesquiterpene lactone		anti-inflammatory agent;
metabolite;
plant metabolite		00low000000
acivicin
0
isoxazoles;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		antileishmanial agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor;
glutamine antagonist;
metabolite		00low000000
n-methylcorydaldine
0
quinolonemetabolite00low000000
2-amino-3,3-dimethylbutanoic acid
0
non-proteinogenic alpha-amino acidmetabolite00low000000
pentabromopseudilin
0
pyrrolesmetabolite00low000000
rocaglamide
0
monocarboxylic acid amide;
monomethoxybenzene;
organic heterotricyclic compound		antileishmanial agent;
antineoplastic agent;
metabolite		00low000000
dentatin
0
coumarinsmetabolite00low000000
acronine
0
acridone derivatives;
alkaloid		antineoplastic agent;
metabolite		00low000000
enmein
0
delta-lactonemetabolite00low000000
5-aminonicotinic acid
0
aminonicotinic acid;
aminopyridine;
aromatic amine		metabolite00low000000
pomolic acid
0
triterpenoidmetabolite00low000000
aglafoline
0
methyl ester;
organic heterotricyclic compound		metabolite;
platelet aggregation inhibitor		00low000000
isomaltose
0
glycosylglucosehuman metabolite;
metabolite;
mouse metabolite		00low000000
deoxyglucose
0
2-deoxy-D-glucosemetabolite00low000000
vestitone
0
(3R)-2'-hydroxyisoflavanones;
hydroxyisoflavanone;
methoxyisoflavanone		antibacterial agent;
metabolite		00low000000
pantetheine
0
pantetheines;
thiol		human metabolite;
metabolite;
mouse metabolite		00low000000
salicin
0
aromatic primary alcohol;
aryl beta-D-glucoside;
benzyl alcohols		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug		00low000000
taxifolin
0
taxifolinmetabolite00low000000
n-formylmethionine
0
L-methionine derivative;
N-formyl amino acid;
proteinogenic amino acid		metabolite00low000000
fucose
0
deoxygalactosemetabolite00low000000
saponarin
0
C-glycosyl compound;
dihydroxyflavone;
glycosyloxyflavone;
monosaccharide derivative		metabolite00low000000
hippeastrine
0
delta-lactone;
indole alkaloid;
organic heteropentacyclic compound;
secondary alcohol		antineoplastic agent;
metabolite		00low000000
cyanidin 3-o-beta-d-glucopyranoside
0
anthocyanin cation;
beta-D-glucoside;
monosaccharide derivative		metabolite00low000000
silychristin
0
1-benzofurans;
aromatic ether;
flavonolignan;
polyphenol;
secondary alpha-hydroxy ketone		lipoxygenase inhibitor;
metabolite;
prostaglandin antagonist;
radical scavenger		00low000000
peonidin
0
5-hydroxyanthocyanidinantineoplastic agent;
antioxidant;
apoptosis inducer;
metabolite		00low000000
convallatoxin
0
14beta-hydroxy steroid;
19-oxo steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
steroid aldehyde;
steroid lactone		metabolite;
vasodilator agent		00low000000
furostanol i
0
beta-D-glucoside;
cyclic hemiketal;
pentacyclic triterpenoid;
steroid saponin;
trisaccharide derivative		metabolite00low000000
decursinol
0
cyclic ether;
delta-lactone;
organic heterotricyclic compound;
secondary alcohol		analgesic;
antineoplastic agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite		00low000000
abyssinone v
0
4'-hydroxyflavanones;
phenols;
trihydroxyflavanone		metabolite00low000000
davidigenin
0
dihydrochalcones;
polyphenol		anti-allergic agent;
anti-asthmatic agent;
antioxidant;
metabolite		00low000000
farrerol
0
organic molecular entitymetabolite00low000000
naringin
0
(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
disaccharide derivative;
neohesperidoside		anti-inflammatory agent;
antineoplastic agent;
metabolite		00low000000
isonaringin
0
(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
disaccharide derivative;
rutinoside		anti-inflammatory agent;
antioxidant;
metabolite		00low000000
cleomiscosin a
0
aromatic ether;
delta-lactone;
organic heterotricyclic compound;
phenols;
primary alcohol		anti-inflammatory agent;
metabolite		00low000000
vicenin ii
0
C-glycosyl compound;
trihydroxyflavone		metabolite00low000000
eugeniin
0
beta-D-glucoside;
ellagitannin;
gallate ester;
lactone		anti-HSV-1 agent;
antifungal agent;
antineoplastic agent;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
metabolite		00low000000
knipholone
0
aromatic ketone;
dihydroxyanthraquinone;
methoxybenzenes;
methyl ketone;
polyphenol;
resorcinols		antineoplastic agent;
antioxidant;
antiplasmodial drug;
leukotriene antagonist;
metabolite		00low000000
alpha bitter acid
0
aromatic ketone;
cyclic ketone;
diketone;
tertiary alpha-hydroxy ketone;
triol		antibacterial drug;
antioxidant;
cyclooxygenase 2 inhibitor;
metabolite		00low000000
acanthoside b
0
beta-D-glucosidemetabolite00low000000
chlorpromazine n-oxide
0
organochlorine compound;
phenothiazines;
tertiary amine oxide		metabolite00low000000
3-hydroxyaspartic acid, (threo-l)-isomer
0
3-hydroxy-L-aspartic acidmetabolite00low000000
cyclo(l-phe-l-pro)
0
organic molecular entitymetabolite00low000000
pyochelin
0
monocarboxylic acid;
phenols;
thiazolidines		metabolite;
siderophore		00low000000
surfactin c
0
cyclodepsipeptide;
lipopeptide antibiotic;
macrocyclic lactone		antibacterial agent;
antifungal agent;
antineoplastic agent;
antiviral agent;
metabolite;
platelet aggregation inhibitor;
surfactant		00low000000
petunidin-3-glucoside
0
anthocyanin cation;
aromatic ether;
beta-D-glucoside		antioxidant;
metabolite		00low000000
malvidin-3-glucoside
0
anthocyanin cation;
aromatic ether;
beta-D-glucoside		metabolite00low000000
dioncophylline a
0
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes;
naphthalenes		antifungal agent;
antimalarial;
metabolite;
molluscicide		00low000000
dioncophylline c
0
aromatic ether;
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes;
naphthols		antimalarial;
antiplasmodial drug;
metabolite		00low000000
latrunculin a
0
cyclic hemiketal;
macrolide;
oxabicycloalkane;
thiazolidinone		actin polymerisation inhibitor;
metabolite;
toxin		00low000000
aglucovancomycin b
0
cyclic ether;
heterodetic cyclic peptide;
peptide antibiotic;
peptide zwitterion;
polyphenol		metabolite00low000000
(S)-ATPA
0
isoxazoles;
non-proteinogenic L-alpha-amino acid		metabolite00low000000
epothilone a
0
epothilone;
epoxide		antineoplastic agent;
metabolite;
microtubule-stabilising agent;
tubulin modulator		00low000000
alitretinoin
0
retinoic acidantineoplastic agent;
keratolytic drug;
metabolite;
retinoid X receptor agonist		00low000000
isoleucylvaline
0
dipeptidemetabolite00low000000
afimoxifene
0
phenols;
tertiary amino compound		antineoplastic agent;
estrogen receptor antagonist;
metabolite		00low000000
3-hydroxyhippuric acid
0
N-acylglycine;
phenols		metabolite00low000000
12-deoxyphorbol 13-acetate
0
phorbol estermetabolite00low000000
conidendrin
0
lignanmetabolite00low000000
bevirimat
0
dicarboxylic acid monoester;
monocarboxylic acid;
pentacyclic triterpenoid		HIV-1 maturation inhibitor;
metabolite		00low000000
azaserine
0
carboxylic ester;
diazo compound;
L-serine derivative;
non-proteinogenic L-alpha-amino acid		antifungal agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
glutamine antagonist;
immunosuppressive agent;
metabolite		00low000000
16beta,17-dihydroxy-ent-kaurane-19-oic acid
0
bridged compound;
diol;
ent-kaurane diterpenoid;
hydroxy monocarboxylic acid;
primary alcohol;
tertiary alcohol		anti-HIV agent;
metabolite		00low000000
glycyrin
0
aromatic ether;
coumarins;
hydroxyisoflavans		antibacterial agent;
metabolite;
plant metabolite		00low000000
reynosin
0
organic heterotricyclic compound;
sesquiterpene lactone		metabolite00low000000
moronic acid
0
pentacyclic triterpenoidanti-HIV agent;
anti-HSV-1 agent;
metabolite		00low000000
maltitol
0
alpha-D-glucoside;
glycosyl alditol		laxative;
metabolite;
sweetening agent		00low000000
Phe-Tyr
0
dipeptidemetabolite00low000000
2-acetyl-1-pyrroline
0
acylimine;
methyl ketone;
pyrroline		flavouring agent;
Maillard reaction product;
metabolite		00low000000
methyl indole-3-carboxylate
0
indoles;
methyl ester		metabolite00low000000
camalexin
0
1,3-thiazoles;
indole phytoalexin		metabolite00low000000
komaroviquinone
0
bridged compound;
lactol;
p-quinones;
tetracyclic diterpenoid		metabolite;
trypanocidal drug		00low000000
2-hydroxycinnamic acid
0
2-coumaric acid;
phenols		antioxidant;
metabolite		00low000000
16-epivincamine
0
alkaloidmetabolite00low000000
diethyl fumarate
0
diestermetabolite00low000000
isoliquiritigenin
0
chalconesantineoplastic agent;
biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
GABA modulator;
geroprotector;
metabolite;
NMDA receptor antagonist		00low000000
1-acetyl-beta-carboline
0
harmala alkaloidmetabolite00low000000
propolin c
0
4'-hydroxyflavanones;
tetrahydroxyflavanone		metabolite;
radical scavenger		00low000000
xanthohumol
0
aromatic ether;
chalcones;
polyphenol		anti-HIV-1 agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor;
metabolite		00low000000
butylidenephthalide
0
2-benzofurans;
gamma-lactone		EC 3.2.1.20 (alpha-glucosidase) inhibitor;
hypoglycemic agent;
metabolite		00low000000
malonyl coenzyme a
0
malonyl-CoAsEC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor;
Escherichia coli metabolite;
metabolite;
mouse metabolite		00low000000
imidazol-1-ylacetic acid
0
imidazolyl carboxylic acidmetabolite00low000000
captax
0
aryl thiol;
benzothiazoles		carcinogenic agent;
metabolite		00low000000
n-acetyltryptophan
0
L-tryptophan derivative;
N-acetyl-L-amino acid		metabolite00low000000
cinnamoylglycine
0
N-acylglycinemetabolite00low000000
n-benzoylalanine
0
N-acyl-L-alanine;
N-benzoylalanine		metabolite00low000000
isoferulic acid
0
ferulic acidsantioxidant;
biomarker;
metabolite		00low000000
oxypeucadanin, (r)-(+)-isomer
0
furanocoumarinmetabolite00low000000
curcumin
0
aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger		00low000000
thiouracil
0
nucleobase analogue;
thiocarbonyl compound		antithyroid drug;
metabolite		00low000000
allylthiourea
0
thioureasmetabolite00low000000
n-glycylalanine
0
dipeptidemetabolite00low000000
caryophyllene oxide
0
epoxidemetabolite00low000000
fumonisin b1
0
diester;
fumonisin;
primary amino compound;
triol		carcinogenic agent;
metabolite		00low000000
olivetolic acid
0
benzoic acids;
monocarboxylic acid;
polyketide;
resorcinols		metabolite00low000000
hirsutine, (16e,20beta)-isomer
0
alkaloidmetabolite00low000000
Ganodermanontriol
0
triterpenoidmetabolite00low000000
dieckol
0
aromatic ether;
oxacycle;
phlorotannin		anticoagulant;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
hepatoprotective agent;
metabolite;
radical scavenger		00low000000
glycylproline
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
tamoxifen n-oxide
0
aromatic ether;
tertiary amine oxide		anti-estrogen;
metabolite		00low000000
7-deacetylgedunin
0
cyclic terpene ketone;
delta-lactone;
enone;
epoxide;
furans;
limonoid;
pentacyclic triterpenoid		anti-inflammatory agent;
antimalarial;
metabolite;
plant metabolite		00low000000
galactose-6-phosphate
0
D-galactose 6-phosphatemetabolite00low000000
nicotine n-glucuronide
0
iminium betaine;
N-glycosylpyridine		metabolite00low000000
isorhyncophylline
0
indolizinesmetabolite00low000000
cysteinylproline
0
dipeptidemetabolite00low000000
glycyllysine
0
dipeptidemetabolite00low000000
methionyltryptophan
0
dipeptidemetabolite00low000000
ascorbigen
0
indolyl carbohydratemetabolite00low000000
pimeloyl-coenzyme a
0
omega-carboxyacyl-CoAmetabolite00low000000
1-salicylate glucuronide
0
benzoic acids;
beta-D-glucosiduronic acid		metabolite00low000000
isoschaftoside
0
C-glycosyl compound;
trihydroxyflavone		metabolite00low000000
croomine
0
alkaloidmetabolite00low000000
3-hydroxyflavanone
0
3'-hydroxyflavanones;
monohydroxyflavanone		metabolite00low000000
ungeremine
0
organic molecular entitymetabolite00low000000
seryl-proline
0
dipeptidemetabolite00low000000
4-hydroxy-5-methyl-3(2h)-furanone
0
cyclic ketone;
enol;
furans		metabolite00low000000
annomontine
0
alkaloid;
aminopyrimidine;
beta-carbolines		antiparasitic agent;
metabolite		00low000000
8-hydroxymanzamine a
0
alkaloid;
beta-carbolines;
isoquinolines		anti-HSV-2 agent;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
metabolite		00low000000
ginkgetin
0
biflavonoid;
hydroxyflavone;
methoxyflavone;
ring assembly		anti-HSV-1 agent;
antineoplastic agent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
metabolite		00low000000
calceolarioside b
0
hydroxycinnamic acidmetabolite00low000000
eupatilin
0
dihydroxyflavone;
trimethoxyflavone		anti-inflammatory agent;
anti-ulcer drug;
antineoplastic agent;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
metabolite		00low000000
quercetin 3-o-glucuronide
0
beta-D-glucosiduronic acid;
quercetin O-glycoside		antidepressant;
antioxidant;
metabolite		00low000000
australifungin
0
carbobicyclic compound;
enol;
enone;
secondary alcohol		antifungal agent;
EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor;
HIV-1 integrase inhibitor;
metabolite		00low000000
catechin gallate
0
flavans;
gallate ester;
polyphenol		metabolite00low000000
sterigmatocystin
0
sterigmatocystinsmetabolite00low000000
3,7-dimethoxy-5,3',4'-trihydroxyflavone
0
dimethoxyflavone;
trihydroxyflavone		EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor;
metabolite		00low000000
apigenin
0
trihydroxyflavoneantineoplastic agent;
metabolite		00low000000
7,3'-dihydroxy-4'-methoxyisoflavone
0
4'-methoxyisoflavones;
7-hydroxyisoflavones		antioxidant;
metabolite		00low000000
calcitriol
0
D3 vitamins;
hydroxycalciol;
triol		antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical		00low000000
vomifoliol
0
(6S)-vomifoliolmetabolite;
phytotoxin		00low000000
feruloyltyramine
0
tyraminesmetabolite00low000000
luteolin-7-glucuronide
0
glycosyloxyflavone;
luteolin O-glucuronoside;
monosaccharide derivative;
trihydroxyflavone		metabolite00low000000
chrysoeriol
0
monomethoxyflavone;
trihydroxyflavone		antineoplastic agent;
antioxidant;
metabolite		00low000000
quercetin 3-o-methyl ether
0
monomethoxyflavone;
tetrahydroxyflavone		antimicrobial agent;
metabolite		00low000000
dexmedetomidine
0
trihydroxyflavone;
trimethoxyflavone		antineoplastic agent;
metabolite		00low000000
apigetrin
0
beta-D-glucoside;
dihydroxyflavone;
glycosyloxyflavone;
monosaccharide derivative		antibacterial agent;
metabolite;
non-steroidal anti-inflammatory drug		00low000000
rutin
0
disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone		antioxidant;
metabolite		00low000000
6-ketoprostaglandin e1
0
prostaglandins Emetabolite;
platelet aggregation inhibitor		00low000000
lipoxin a4
0
hydroxy polyunsaturated fatty acid;
lipoxin;
long-chain fatty acid		human metabolite;
metabolite		00low000000
harmine
0
harmala alkaloidanti-HIV agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
metabolite		00low000000
naringenin chalcone
0
chalcones;
polyphenol		anti-allergic agent;
anti-inflammatory agent;
metabolite		00low000000
cornexistin
0
cyclic dicarboxylic anhydride;
organic heterobicyclic compound;
secondary alpha-hydroxy ketone		herbicide;
metabolite		00low000000
isobavachalcone
0
chalcones;
polyphenol		antibacterial agent;
metabolite;
platelet aggregation inhibitor		00low000000
daphnoretin
0
aromatic ether;
hydroxycoumarin		antineoplastic agent;
antiviral agent;
metabolite		00low000000
Rhynchophylline
0
indolizinesmetabolite00low000000
esculin
0
beta-D-glucoside;
hydroxycoumarin		antioxidant;
metabolite		00low000000
mammeisin
0
neoflavonoidmetabolite00low000000
ostruthin
0
terpene lactonemetabolite00low000000
costunolide
0
germacranolide;
heterobicyclic compound		anthelminthic drug;
antiinfective agent;
antineoplastic agent;
antiparasitic agent;
antiviral drug;
metabolite		00low000000
caryophyllene
0
beta-caryophyllenefragrance;
insect attractant;
metabolite;
non-steroidal anti-inflammatory drug		00low000000
phaseic acid
0
alpha,beta-unsaturated monocarboxylic acid;
apo carotenoid sesquiterpenoid		metabolite00low000000
agathisflavone
0
biaryl;
biflavonoid;
hydroxyflavone		antineoplastic agent;
antiviral agent;
hepatoprotective agent;
metabolite		00low000000
cupressuflavone
0
biflavonoid;
hydroxyflavone;
ring assembly		EC 3.4.21.37 (leukocyte elastase) inhibitor;
metabolite;
radical scavenger		00low000000
fisetin
0
3'-hydroxyflavonoid;
7-hydroxyflavonol;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
metabolite;
plant metabolite		00low000000
genkwanin
0
dihydroxyflavone;
monomethoxyflavone		metabolite00low000000
bellidifolin
0
polyphenol;
xanthones		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
hypoglycemic agent;
metabolite		00low000000
demethylbellidifolin
0
tetrol;
xanthones		antioxidant;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite;
mutagen;
radical scavenger		00low000000
hinokiflavone
0
aromatic ether;
biflavonoid;
hydroxyflavone		antineoplastic agent;
metabolite;
neuroprotective agent		00low000000
euxanthone
0
phenols;
xanthones		metabolite;
plant metabolite		00low000000
3-methylquercetin
0
7-hydroxyflavonol;
monomethoxyflavone;
tetrahydroxyflavone		anticoagulant;
EC 1.14.18.1 (tyrosinase) inhibitor;
metabolite		00low000000
norswertianolin
0
beta-D-glucoside;
xanthones		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite		00low000000
swerchirin
0
aromatic ether;
phenols;
xanthones		hypoglycemic agent;
metabolite		00low000000
isoscutellarein
0
tetrahydroxyflavonemetabolite00low000000
kaempferide
0
7-hydroxyflavonol;
monomethoxyflavone;
trihydroxyflavone		antihypertensive agent;
metabolite		00low000000
morin
0
7-hydroxyflavonol;
pentahydroxyflavone		angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent		00low000000
norwogonin
0
trihydroxyflavoneantioxidant;
metabolite		00low000000
orientin
0
3'-hydroxyflavonoid;
C-glycosyl compound;
tetrahydroxyflavone		antioxidant;
metabolite		00low000000
patuletin
0
flavonols;
monomethoxyflavone;
pentahydroxyflavone		analgesic;
antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
lipoxygenase inhibitor;
metabolite		00low000000
rhamnetin
0
monomethoxyflavone;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
metabolite		00low000000
robustaflavone
0
biflavonoid;
hydroxyflavone;
ring assembly		anti-HBV agent;
antineoplastic agent;
antioxidant;
metabolite		00low000000
scutellarein
0
tetrahydroxyflavonemetabolite00low000000
tricetin
0
pentahydroxyflavoneantineoplastic agent;
metabolite		00low000000
tricin
0
3'-methoxyflavones;
dimethoxyflavone;
trihydroxyflavone		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
metabolite		00low000000
astringin
0
beta-D-glucoside;
monosaccharide derivative;
polyphenol;
stilbenoid		antineoplastic agent;
antioxidant;
metabolite		00low000000
polydatin
0
beta-D-glucoside;
monosaccharide derivative;
polyphenol;
stilbenoid		anti-arrhythmia drug;
antioxidant;
geroprotector;
hepatoprotective agent;
metabolite;
nephroprotective agent;
potassium channel modulator		00low000000
epsilon-viniferin
0
1-benzofurans;
polyphenol;
stilbenoid		metabolite00low000000
irilone
0
hydroxyisoflavone;
organic heterotricyclic compound;
oxacycle		antineoplastic agent;
immunomodulator;
metabolite		00low000000
caffeic acid phenethyl ester
0
alkyl caffeate esteranti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiviral agent;
immunomodulator;
metabolite;
neuroprotective agent		00low000000
licoisoflavone a
0
7-hydroxyisoflavonesmetabolite00low000000
prunetin
0
7-methoxyisoflavones;
hydroxyisoflavone		anti-inflammatory agent;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor;
metabolite		00low000000
wedelolactone
0
aromatic ether;
coumestans;
delta-lactone;
polyphenol		antineoplastic agent;
apoptosis inducer;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
hepatoprotective agent;
metabolite		00low000000
rottlerin
0
aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite		00low000000
syringetin
0
3',5'-dimethoxyflavone;
3'-methoxyflavones;
7-hydroxyflavonol;
dimethoxyflavone;
tetrahydroxyflavone		metabolite;
platelet aggregation inhibitor		00low000000
10-deoxymethynolide
0
macrolidemetabolite00low000000
4',7-dihydroxyflavone
0
dihydroxyflavonemetabolite00low000000
rhoifolin
0
dihydroxyflavone;
glycosyloxyflavone;
neohesperidoside		metabolite00low000000
veronicastroside
0
disaccharide derivative;
glycosyloxyflavone;
neohesperidoside;
trihydroxyflavone		antibacterial agent;
metabolite		00low000000
quercimeritrin
0
beta-D-glucoside;
flavonols;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antioxidant;
metabolite		00low000000
josamycin
0
acetate ester;
aldehyde;
disaccharide derivative;
glycoside;
macrolide antibiotic;
tertiary alcohol;
tertiary amino compound		antibacterial drug;
metabolite		00low000000
n,n-dimethylsphingenine
0
aminodiol;
sphingoid;
tertiary amino compound		EC 2.7.1.91 (sphingosine kinase) inhibitor;
metabolite		00low000000
4-hydroxyestradiol
0
4-hydroxy steroidmetabolite00low000000
9-hydroxy-10,12-octadecadienoic acid
0
HODE;
octadecadienoic acid		human metabolite;
metabolite;
mouse metabolite;
plant metabolite		00low000000
9-oxo-10,12-octadecadienoic acid
0
enone;
oxooctadecadienoic acid		metabolite00low000000
13-oxo-9,11-octadecadienoic acid
0
13-oxo-9,11-octadecadienoic acid;
oxo fatty acid		metabolite00low000000
13,14-dihydro-15-ketoprostaglandin d2
0
prostaglandins Dmetabolite00low000000
15-keto-13,14-dihydroprostaglandin f2alpha
0
ketone;
prostaglandins Falpha		metabolite00low000000
2,3-dinor-6-ketoprostaglandin f1alpha
0
4-oxo monocarboxylic acid;
prostanoid;
secondary alcohol		metabolite00low000000
ergosta-7,22-dien-3-ol, (3beta,5alpha,6alpha,22e)-isomer
0
3beta-sterolanti-HSV-1 agent;
antifungal agent;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
metabolite		00low000000
calcifediol
0
D3 vitamins;
diol;
hydroxycalciol		bone density conservation agent;
human metabolite;
metabolite;
mouse metabolite;
nutraceutical		00low000000
cyclosporine
0
homodetic cyclic peptideanti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite		00low000000
oleyl alcohol
0
fatty alcohol 18:1;
long-chain primary fatty alcohol		metabolite;
nonionic surfactant		00low000000
fortimicin a
0
amino cyclitol glycoside;
aminoglycoside antibiotic;
diol;
monocarboxylic acid amide;
primary amino compound		antibacterial agent;
metabolite		00low000000
3',4',7-trihydroxyisoflavone
0
7-hydroxyisoflavonesantineoplastic agent;
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor;
metabolite		00low000000
6,7,4'-trihydroxyisoflavone
0
7-hydroxyisoflavonesanti-inflammatory agent;
antimutagen;
EC 1.14.18.1 (tyrosinase) inhibitor;
metabolite;
PPARalpha agonist;
PPARgamma agonist		00low000000
15-deoxy-delta(12,14)-prostaglandin j2
0
prostaglandins Jelectrophilic reagent;
insulin-sensitizing drug;
metabolite		00low000000
cytochalasin b
0
cytochalasin;
lactam;
lactone;
organic heterotricyclic compound		actin polymerisation inhibitor;
metabolite;
mycotoxin;
platelet aggregation inhibitor		00low000000
ciguatoxins
0
ciguatoxinmetabolite00low000000
12-hydroxy-5,8,10-heptadecatrienoic acid
0
hydroxy polyunsaturated fatty acid;
long-chain fatty acid;
trienoic fatty acid		metabolite00low000000
bisdemethoxycurcumin
0
beta-diketone;
diarylheptanoid;
enone;
polyphenol		EC 3.2.1.1 (alpha-amylase) inhibitor;
metabolite		00low000000
clausine e
0
carbazolesmetabolite00low000000
ethyl caffeate
0
alkyl caffeate ester;
ethyl ester;
hydroxycinnamic acid		anti-inflammatory agent;
antineoplastic agent;
metabolite		00low000000
heptaphylline
0
carbazolesmetabolite00low000000
pellitorine
0
fatty amidemetabolite00low000000
andrographolide
0
carbobicyclic compound;
gamma-lactone;
labdane diterpenoid;
primary alcohol;
secondary alcohol		anti-HIV agent;
anti-inflammatory drug;
antineoplastic agent;
metabolite		00low000000
isorhamnetin-3-o-galactoside
0
beta-D-galactoside;
glycosyloxyflavone;
monomethoxyflavone;
monosaccharide derivative;
trihydroxyflavone		metabolite00low000000
isorhamnetin 3-o-glucoside
0
beta-D-glucoside;
glycosyloxyflavone;
monomethoxyflavone;
monosaccharide derivative;
trihydroxyflavone		metabolite00low000000
kaempferol-3-o-rutinoside
0
disaccharide derivative;
kaempferol O-glucoside;
rutinoside;
trihydroxyflavone		metabolite;
plant metabolite;
radical scavenger		00low000000
ligustilide
0
butenolidemetabolite00low000000
7,4'-dihydroxy-3'-methoxyisoflavone
0
7-hydroxyisoflavones;
methoxyisoflavone		antiplasmodial drug;
metabolite		00low000000
sappanchalcone
0
catechols;
chalcones;
monomethoxybenzene		anti-allergic agent;
anti-inflammatory agent;
antioxidant;
metabolite		00low000000
methyl brevifolincarboxylate
0
cyclic ketone;
delta-lactone;
organic heterotricyclic compound;
phenols		EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
metabolite;
platelet aggregation inhibitor;
radical scavenger;
vasodilator agent		00low000000
3-deoxysappanchalcone
0
chalcones;
monomethoxybenzene;
phenols		metabolite00low000000
nostocarboline
0
alkaloid;
beta-carbolines;
organic cation;
organochlorine compound		antimalarial;
EC 3.1.1.8 (cholinesterase) inhibitor;
metabolite		00low000000
ergosterol-5,8-peroxide
0
3beta-sterol;
ergostanoid;
organic peroxide;
phytosterols		antimycobacterial drug;
antineoplastic agent;
metabolite;
trypanocidal drug		00low000000
3-(4-hydroxy-3-methoxyphenyl)-n-(2-(4-hydroxy-3-methoxyphenyl)ethyl)-2-propenamide
0
hydroxycinnamic acidmetabolite00low000000
macluraxanthone b
0
phenols;
xanthones		anti-HIV agent;
antineoplastic agent;
metabolite		00low000000
flavokawain b
0
chalcones;
dimethoxybenzene;
phenols		anti-inflammatory agent;
antileishmanial agent;
antineoplastic agent;
apoptosis inducer;
metabolite		00low000000
alternariol
0
benzochromenone;
phenols		EC 3.1.1.8 (cholinesterase) inhibitor;
metabolite;
mycotoxin		00low000000
cis-3-hexenyl acetate
0
acetate ester;
olefinic compound		metabolite00low000000
pipercallosidine
0
alkaloid;
benzodioxoles;
enamide;
secondary carboxamide		apoptosis inducer;
metabolite;
plant metabolite		00low000000
n-(4-hydroxy-beta-phenethyl)-4-hydroxycinnamide
0
hydroxycinnamic acidmetabolite00low000000
7-hydroxyisoflavone
0
7-hydroxyisoflavonesEC 1.14.14.14 (aromatase) inhibitor;
metabolite		00low000000
flazin
0
harmala alkaloidmetabolite00low000000
11-hydroxynoracronycine
0
acridinesmetabolite00low000000
jaceosidin
0
dimethoxyflavone;
trihydroxyflavone		anti-allergic agent;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
metabolite		00low000000
5,7,3'-trihydroxy-3,4'-dimethoxyflavone
0
dimethoxyflavone;
trihydroxyflavone		antineoplastic agent;
metabolite		00low000000
salutaridine
0
morphinane alkaloidanti-HBV agent;
metabolite		00low000000
cytochalasin e
0
cytochalasan alkaloidmetabolite00low000000
artocarpin lectin
0
monomethoxyflavone;
trihydroxyflavone		antineoplastic agent;
metabolite		00low000000
fumarates
0
butenedioate;
C4-dicarboxylate		human metabolite;
metabolite;
Saccharomyces cerevisiae metabolite		00low000000
bleomycin
0
bleomycinantineoplastic agent;
metabolite		00low000000
1,7-dihydroxy-4-methoxyxanthone
0
aromatic ether;
phenols;
xanthones		metabolite;
plant metabolite		00low000000
demethoxycurcumin
0
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antineoplastic agent;
metabolite		00low000000
bergamottin
0
furanocoumarinmetabolite00low000000
alanyl-alanyl-alanine
0
tripeptidemetabolite00low000000
24-ethyl-4-cholesten-3-one
0
C29-steroid;
steroid		metabolite00low000000
myricetin 3-o-glucuronide
0
monosaccharide derivative;
myricetin O-glucuronide;
pentahydroxyflavone		metabolite00low000000
phenylalanylalanine
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
alpinumisoflavone
0
isoflavanonesmetabolite00low000000
alpha-aspartylalanine
0
dipeptidemetabolite00low000000
alanyltyrosine
0
dipeptidemetabolite00low000000
arglabin
0
epoxide;
gamma-lactone;
organic heterotetracyclic compound;
sesquiterpene lactone		antineoplastic agent;
metabolite		00low000000
ap 10
0
diterpene lactonemetabolite00low000000
quercetin 7-rhamnoside
0
alpha-L-rhamnoside;
flavonols;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		metabolite00low000000
albonoursin
0
2,5-diketopiperazinesmetabolite00low000000
oroidin
0
pyrroles;
secondary carboxamide		metabolite00low000000
monorden
0
cyclic ketone;
enone;
epoxide;
macrolide antibiotic;
monochlorobenzenes;
phenols		antifungal agent;
metabolite;
tyrosine kinase inhibitor		00low000000
apratoxin a
0
1,3-thiazoles;
apratoxin		antineoplastic agent;
metabolite		00low000000
(-)-catechin-3-O-gallate
0
flavans;
gallate ester;
polyphenol		metabolite00low000000
aspartyllysine
0
dipeptidemetabolite00low000000
arginyllysine
0
dipeptidemetabolite00low000000
hygromycin a
0
hydroxycinnamic acidmetabolite00low000000
latrunculin b
0
cyclic hemiketal;
macrolide;
oxabicycloalkane;
thiazolidinone		actin polymerisation inhibitor;
metabolite;
toxin		00low000000
falcarindiol
0
organic molecular entitymetabolite00low000000
dehydroergosterol
0
3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		biomarker;
metabolite		00low000000
n-oleoylglycine
0
fatty amide;
N-acylglycine 18:1		metabolite00low000000
rhizoxin
0
1,3-oxazoles;
epoxide;
macrolide antibiotic		antimitotic;
antineoplastic agent;
metabolite		00low000000
manoalide
0
butenolide;
lactol;
sesterterpenoid		EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
metabolite		00low000000
concanamycin a
0
carbamate ester;
concanamycin		antifungal agent;
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor;
metabolite		00low000000
n(3)-(4-methoxyfumaroyl)-2,3-diaminopropionic acid
0
enoate ester;
methyl ester;
monocarboxylic acid amide		metabolite00low000000
thunberginol f
0
catechols;
gamma-lactone;
isobenzofuranone		metabolite;
plant metabolite		00low000000
pyracrenic acid
0
triterpenoidmetabolite00low000000
eicosa-11,14-dienoic acid, (z,z)-isomer
0
icosadienoic acidmetabolite00low000000
yuanhuadine
0
diterpenoidmetabolite00low000000
tiglylglycine
0
N-acylglycinemetabolite00low000000
rhodiocyanoside a
0
aliphatic nitrile;
beta-D-glucoside;
cyanogenic glycoside;
monosaccharide derivative		anti-allergic agent;
metabolite		00low000000
(2E,4E)-N-isobutyl-2,4-dodecadienamide
0
fatty amidemetabolite00low000000
mycothiazole
0
thiazolesmetabolite00low000000
13-oxo-9,11-octadecadienoic acid
0
13-oxo-9,11-octadecadienoic acidmetabolite;
mouse metabolite		00low000000
linderalactone
0
butenolidemetabolite00low000000
pros-methylimidazoleacetic acid
0
imidazolyl carboxylic acidmetabolite00low000000
cellobionic acid
0
carbohydrate acid;
disaccharide		metabolite00low000000
pseudopteroxazole
0
tetralinsmetabolite00low000000
sophoraflavanone a
0
(2S)-flavan-4-one;
4'-hydroxyflavanones;
trihydroxyflavanone		antibacterial agent;
antineoplastic agent;
metabolite		00low000000
panduratin a
0
diarylheptanoidmetabolite00low000000
stigmasterol 3-o-beta-d-glucopyranoside
0
beta-D-glucoside;
monosaccharide derivative;
phytosterols;
steroid saponin		metabolite00low000000
17-hydroxyjolkinolide b
0
diterpene lactonemetabolite00low000000
sq-23377
0
cyclic ether;
enol;
polyunsaturated fatty acid;
very long-chain fatty acid		calcium ionophore;
metabolite		00low000000
corosolic acid
0
triterpenoidmetabolite00low000000
cyclo(prolyl-valyl)
0
piperazinonemetabolite00low000000
phenylalanylglycine
0
dipeptidemetabolite00low000000
leucyl-phenylalanine
0
dipeptidemetabolite00low000000
glutamylalanine
0
dipeptidemetabolite00low000000
glutaminyl-glycine
0
dipeptidemetabolite00low000000
methionylglycine
0
dipeptidemetabolite00low000000
valylleucine
0
dipeptidemetabolite00low000000
phenylalanyl-valine
0
dipeptidemetabolite00low000000
cyclo(glycyltryptophyl)
0
indolesmetabolite00low000000
alanylglycine
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
valyltyrosine
0
dipeptidemetabolite00low000000
alpha-glutamyltryptophan
0
dipeptidemetabolite00low000000
lysylglutamic acid
0
dipeptidemetabolite00low000000
methionylglutamic acid
0
dipeptidemetabolite00low000000
seryl-histidine
0
dipeptidemetabolite00low000000
arginyl-glutamine
0
dipeptidemetabolite00low000000
phenylalanylproline
0
dipeptidemetabolite00low000000
lysylglycine
0
dipeptidemetabolite00low000000
glycylhistidine
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
kopsinine
0
indole alkaloidmetabolite00low000000
cyclo(leucyl-phenylalanyl)
0
2,5-diketopiperazinesmetabolite00low000000
prolylisoleucine
0
dipeptidemetabolite00low000000
phenylalanyl-valine
0
dipeptidemetabolite00low000000
isoleucyl-tyrosine
0
dipeptidemetabolite00low000000
prolyl-serine
0
dipeptidemetabolite00low000000
grayanotoxin i
0
acetate ester;
pentol;
secondary alcohol;
tertiary alcohol;
tetracyclic diterpenoid		antihypertensive agent;
metabolite;
neuromuscular agent;
phytotoxin		00low000000
19-norandrosterone
0
17-oxo steroidmetabolite00low000000
s-allylcysteine
0
L-alpha-amino acid zwitterion;
S-hydrocarbyl-L-cysteine		antineoplastic agent;
metabolite		00low000000
oleandrigenin
0
14beta-hydroxy steroid;
3beta-hydroxy steroid;
steroid ester		EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
metabolite		00low000000
valyl-prolyl-proline
0
tripeptidemetabolite00low000000
prolylvaline
0
dipeptidemetabolite00low000000
palbinone
0
16-oxo steroidmetabolite00low000000
pseurotin
0
azaspiro compound;
lactam;
oxaspiro compound		metabolite00low000000
gambogic acid
0
pyranoxanthonesmetabolite00low000000
xenovulene a
0
cyclic ether;
enone;
organic heterotetracyclic compound;
sesquiterpenoid		GABA antagonist;
metabolite		00low000000
fr 148083
0
aromatic ether;
macrolide;
phenols;
secondary alcohol;
secondary alpha-hydroxy ketone		antibacterial agent;
antineoplastic agent;
metabolite;
NF-kappaB inhibitor		00low000000
LL-Z1640-1
0
macrolide;
resorcinols		metabolite00low000000
9-methoxycanthin-6-one
0
aromatic ether;
indole alkaloid;
organic heterotetracyclic compound		antineoplastic agent;
antiplasmodial drug;
metabolite		00low000000
n-acetylcarnosine
0
dipeptidemetabolite00low000000
cholest-5-en-3-one
0
3-oxo-Delta(5)-steroid;
cholestanoid		metabolite00low000000
kaempferol 3-O-beta-L-glucopyranoside
0
beta-L-glucoside;
flavonols;
kaempferol O-glucoside;
monosaccharide derivative;
trihydroxyflavone		metabolite00low000000
rubraxanthone
0
aromatic ether;
polyphenol;
xanthones		antibacterial agent;
antineoplastic agent;
metabolite		00low000000
ubiquinol
0
polyprenylhydroquinone;
ubiquinol		biomarker;
metabolite		00low000000
landomycin a
0
oligosaccharidemetabolite00low000000
ancistroealaine a
0
aromatic ether;
biaryl;
isoquinoline alkaloid;
isoquinolines;
methoxynaphthalene;
methylnaphthalenes		antileishmanial agent;
antiplasmodial drug;
metabolite;
trypanocidal drug		00low000000
cerberin
0
acetate ester;
cardenolide glycoside;
monosaccharide derivative		antineoplastic agent;
metabolite		00low000000
actein
0
triterpenoidmetabolite00low000000
araloside a
0
triterpenoid saponinmetabolite00low000000
ageladine a
0
alkaloid;
aromatic amine;
imidazopyridine;
organobromine compound;
pyrroles		angiogenesis inhibitor;
antineoplastic agent;
matrix metalloproteinase inhibitor;
metabolite		00low000000
corynoxine b
0
indolizinesmetabolite00low000000
kaempferol 7-o-glucoside
0
beta-D-glucoside;
flavonols;
kaempferol O-glucoside;
monosaccharide derivative;
trihydroxyflavone		metabolite;
plant metabolite;
radical scavenger		00low000000
delphinidin 3-sambubioside
0
anthocyanidin 3-O-beta-D-sambubiosideapoptosis inducer;
metabolite		00low000000
nodosin
0
delta-lactonemetabolite00low000000
protylonolide
0
diol;
enone;
macrolide		metabolite00low000000
arisugacin
0
aromatic ether;
delta-lactone;
enone;
organic heterotetracyclic compound;
tertiary alcohol		antimicrobial agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite;
Penicillium metabolite		00low000000
nymphaeol c
0
4'-hydroxyflavanones;
tetrahydroxyflavanone		metabolite;
radical scavenger		00low000000
thonningianin a
0
tanninmetabolite00low000000
cephalostatin i
0
oxo steroidmetabolite00low000000
papyriflavonol a
0
3'-hydroxyflavonoid;
flavonols;
pentahydroxyflavone		EC 1.14.18.1 (tyrosinase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
metabolite		00low000000
lactonamycin
0
gamma-lactone;
organic heterohexacyclic compound;
phenols;
trideoxyhexose derivative		antibacterial agent;
antimicrobial agent;
metabolite		00low000000
myrsinoic acid b
0
1-benzofurans;
monocarboxylic acid		anti-inflammatory agent;
EC 4.4.1.11 (methionine gamma-lyase) inhibitor;
metabolite		00low000000
betulone
0
triterpenoidmetabolite00low000000
eckstolonol
0
organic heteropentacyclic compound;
oxacycle;
phlorotannin		metabolite;
radical scavenger		00low000000
manassantin b
0
benzodioxoles;
dimethoxybenzene;
lignan;
oxolanes;
secondary alcohol		antineoplastic agent;
metabolite		00low000000
gitaloxin
0
cardenolide glycosidemetabolite00low000000
paeonilide
0
benzoate estermetabolite00low000000
dihydroxanthohumol
0
aromatic ether;
dihydrochalcones;
polyphenol		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
metabolite		00low000000
corynoxine
0
indolizinesmetabolite00low000000
7-phloroeckol
0
aromatic ether;
phlorotannin		antioxidant;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
metabolite		00low000000
(+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside
0
beta-D-glucoside;
dimethoxybenzene;
lignan;
monosaccharide derivative;
polyphenol;
primary alcohol;
tetralins		antibacterial agent;
antifungal agent;
metabolite		00low000000
Sphaeropsidin C
0
tricyclic diterpenoidmetabolite00low000000
kelampayoside a
0
glycosidemetabolite00low000000
3,5-dimethoxy-4-hydroxybenzyl alcohol-4-O-beta-D-glucopyranoside
0
aromatic ether;
benzyl alcohols;
beta-D-glucoside;
monosaccharide derivative;
primary alcohol		antineoplastic agent;
metabolite		00low000000
2,3-dihydro-3beta-methoxy withaferin A
0
27-hydroxy steroid;
4-hydroxy steroid;
delta-lactone;
epoxy steroid;
ergostanoid;
primary alcohol;
secondary alcohol;
withanolide		metabolite;
plant metabolite		00low000000
nigranoic acid
0
dicarboxylic acid;
tetracyclic triterpenoid		antineoplastic agent;
HIV-1 reverse transcriptase inhibitor;
metabolite		00low000000
esculeoside a
0
azaspiro compound;
oxaspiro compound;
saponin;
steroid alkaloid;
steroid saponin		antineoplastic agent;
metabolite		00low000000
aerothionin
0
isoxazolesmetabolite00low000000
artemisic acid
0
carbobicyclic compound;
monocarboxylic acid;
octahydronaphthalenes;
sesquiterpenoid		metabolite00low000000
26-deoxyactein
0
triterpenoidmetabolite00low000000
5-formylcytosine
0
aminopyrimidine;
heteroarenecarbaldehyde;
nucleobase analogue;
pyrimidone		metabolite00low000000
migrastatin
0
ether;
macrolide antibiotic;
piperidones;
secondary alcohol		antineoplastic agent;
metabolite		00low000000
Lyngbic acid
0
long-chain fatty acidmetabolite00low000000
2,3,6,8-tetrahydroxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9h-xanthen-9-one
0
polyphenol;
xanthones		anti-inflammatory agent;
antineoplastic agent;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
metabolite		00low000000
bielschowskysin
0
acetate ester;
cyclic acetal;
diterpenoid;
gamma-lactone;
organic heterohexacyclic compound		antimalarial;
antineoplastic agent;
metabolite		00low000000
procyanidin b1
0
biflavonoid;
hydroxyflavan;
polyphenol;
proanthocyanidin		anti-inflammatory agent;
EC 3.4.21.5 (thrombin) inhibitor;
metabolite		00low000000
cyclo(tyrosyl-tyrosyl)
0
cyclo(tyrosyl-tyrosyl)metabolite00low000000
spiculoic acid a
0
carbobicyclic compound;
cyclic ketone;
oxo monocarboxylic acid;
styrenes		antineoplastic agent;
metabolite		00low000000
myrocin a
0
tertiary alcoholmetabolite00low000000
3'-o-methylepicatechin
0
catechinmetabolite00low000000
episilvestrol
0
dioxanes;
ether;
methyl ester;
organic heterotricyclic compound		antineoplastic agent;
metabolite		00low000000
protopanaxatriol
0
12beta-hydroxy steroid;
3beta-hydroxy-4,4-dimethylsteroid;
3beta-hydroxy steroid;
6alpha-hydroxy steroid;
sapogenin;
tetracyclic triterpenoid		metabolite00low000000
laurinterol
0
organobromine compound;
phenols;
sesquiterpenoid		antibacterial agent;
apoptosis inducer;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
metabolite		00low000000
Pseudopterosin G-J aglycone
0
diterpenoidmetabolite00low000000
ceratamine a
0
alkaloid;
aromatic ether;
cyclic ketone;
organic heterobicyclic compound;
organobromine compound;
secondary amino compound;
tertiary amine		antimitotic;
metabolite		00low000000
liphagal
0
aldehyde;
cyclic ether;
meroterpenoid;
organic heterotetracyclic compound;
polyphenol		EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
metabolite		00low000000
pulsatilla saponin d
0
triterpenoidmetabolite00low000000
diversonol
0
phenols;
tertiary alcohol		antibacterial agent;
metabolite		00low000000
neotuberostemonine
0
alkaloidmetabolite00low000000
drymaritin
0
enol ether;
enone;
indole alkaloid;
organic heterotetracyclic compound		anti-HIV agent;
metabolite		00low000000
lyoniresinol
0
dimethoxybenzene;
lignan;
polyphenol;
primary alcohol;
tetralins		antineoplastic agent;
metabolite		00low000000
silvestrol
0
dioxanes;
ether;
methyl ester;
organic heterotricyclic compound		antineoplastic agent;
metabolite		00low000000
ginsenoside ro
0
triterpenoid saponinmetabolite00low000000
diosgenin glucoside
0
hexacyclic triterpenoid;
monosaccharide derivative;
spiroketal;
sterol 3-beta-D-glucoside		metabolite00low000000
pyripyropene a
0
organic heterotetracyclic compound;
sesquiterpenoid		acyl-CoA:cholesterol acyltransferase 2 inhibitor;
metabolite		00low000000
3-epioleanolic acid
0
triterpenoidmetabolite00low000000
leucylproline
0
dipeptide zwitterion;
dipeptide		metabolite00low000000
R-(-)-actinodaphnine
0
aporphine alkaloidmetabolite00low000000
cytotrienin a
0
cyclopropanecarboxylate ester;
ether;
hydroquinones;
lactam;
macrocycle;
secondary alcohol		antibacterial agent;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
metabolite		00low000000
methylamphotericin b
0
macrolide;
methyl ester;
monosaccharide derivative		antifungal agent;
antiinfective agent;
metabolite		00low000000
2'-methoxykurarinone
0
4'-hydroxyflavanones;
dihydroxyflavanone;
dimethoxyflavanone		antineoplastic agent;
metabolite		00low000000
verproside
0
glycosidemetabolite00low000000
verminoside
0
hydroxycinnamic acidmetabolite00low000000
minecoside
0
hydroxycinnamic acidmetabolite00low000000
(R)-(+)-6',7'-dihydroxybergamottin
0
furanocoumarinmetabolite00low000000
lapidilectine b
0
indolyl carboxylic acidmetabolite00low000000
batzelladine a
0
alkaloid;
carboxylic ester;
guanidines;
organic heterotricyclic compound;
pyrrolopyrimidine;
triazaacenaphthylene		anti-HIV-1 agent;
metabolite		00low000000
alloin
0
anthracenes;
C-glycosyl compound;
cyclic ketone;
phenols		laxative;
metabolite		00low000000
longipinene
0
alpha-longipinenemetabolite00low000000
parkeol
0
3beta-hydroxy-4,4-dimethylsteroid;
3beta-sterol;
tetracyclic triterpenoid		metabolite00low000000
rutundic acid
0
triterpenoidmetabolite00low000000
a-factor (streptomyces)
0
butan-4-olide;
primary alcohol		metabolite00low000000
taraxasteryl acetate
0
triterpenoidmetabolite00low000000
chikusetsu saponin iva
0
triterpenoid saponinmetabolite00low000000
xestoaminol c
0
amino alcohol;
sphingoid		metabolite00low000000
malyngamide A
0
dicarboximidemetabolite00low000000
simalikalactone D
0
cyclic ether;
delta-lactone;
enone;
organic heteropentacyclic compound;
quassinoid;
secondary alcohol;
secondary alpha-hydroxy ketone;
triol		antimalarial;
antineoplastic agent;
antiviral agent;
metabolite		00low000000
friedelane
0
triterpenemetabolite00low000000
shamixanthone
0
cyclic ketone;
phenols;
pyranoxanthene		metabolite00low000000
17,18-epoxy-5,8,11,14-eicosatetraenoic acid
0
EpETEmetabolite00low000000
chaetominine
0
indole alkaloid;
lactam;
organic heterotetracyclic compound;
quinazolines		metabolite00low000000
schweinfurthin g
0
cyclic ether;
organic heterotricyclic compound;
resorcinols;
stilbenoid		antineoplastic agent;
metabolite		00low000000
salmon calcitonin
0
heterodetic cyclic peptide;
peptide hormone;
polypeptide		bone density conservation agent;
metabolite		00low000000
complestatin
0
cyclic ether;
heterodetic cyclic peptide;
indoles;
organic heterobicyclic compound;
organochlorine compound;
peptide antibiotic;
polyphenol		anti-HIV-1 agent;
antimicrobial agent;
HIV-1 integrase inhibitor;
metabolite		00low000000
neuroprotectin a
0
cyclic ether;
heterodetic cyclic peptide;
indoles;
organochlorine compound;
polyphenol		HIV-1 integrase inhibitor;
metabolite		00low000000
alx-0600
0
polypeptideantioxidant;
glucagon-like peptide-2 receptor agonist;
metabolite;
protective agent		00low000000
schweinfurthin f
0
cyclic ether;
organic heterotricyclic compound;
resorcinols;
stilbenoid		metabolite00low000000
antrocamphin a
0
methoxybenzenesanti-inflammatory agent;
metabolite		00low000000
respirantin
0
benzamides;
cyclodepsipeptide;
formamides;
phenols		antimicrobial agent;
antineoplastic agent;
metabolite		00low000000
streptobiosamine
0
amino disaccharidemetabolite00low000000
interiotherin b
0
aromatic ether;
fatty acid ester;
lignan;
organic heteropentacyclic compound;
oxacycle		anti-HIV agent;
metabolite		00low000000
succinyladenosine
0
adenosines;
amino dicarboxylic acid;
L-aspartic acid derivative		metabolite00low000000
6-tuliposide a
0
6-O-acyl-D-glucose;
homoallylic alcohol		allergen;
metabolite		00low000000
glycochenodeoxycholate-3-sulfate
0
7alpha-hydroxy steroid;
bile acid glycine conjugate;
steroid sulfate		metabolite00low000000
wewakazole
0
cyclic peptidemetabolite00low000000
spongia-13(16),14-dien-19-oic acid
0
cyclic ether;
monocarboxylic acid;
tetracyclic diterpenoid		androgen antagonist;
metabolite		00low000000
Icariside E4
0
benzofuransmetabolite00low000000
lucidenic acid n
0
cyclic terpene ketone;
dioxo monocarboxylic acid;
secondary alcohol;
tetracyclic triterpenoid		antineoplastic agent;
EC 3.1.1.8 (cholinesterase) inhibitor;
metabolite		00low000000
dihydroagarofuran
0
bridged compound;
cyclic ether;
eudesmane sesquiterpenoid;
organic heterotricyclic compound		metabolite00low000000
23-epi-26-deoxyactein
0
triterpenoidmetabolite00low000000
23-hydroxybetulinic acid
0
triterpenoidmetabolite00low000000
(1S,3aR,4S,6S,6aS,9aS,9bS)-9a-isocyano-6-(2-isocyano-2-methylpropyl)-1,4-dimethyl-7-methylidene-2,3,3a,4,5,6,6a,8,9,9b-decahydro-1H-phenalene
0
diterpenoidmetabolite00low000000
bromophycolide a
0
diterpenoid;
macrolide;
organobromine compound;
phenols;
tertiary alcohol		anti-HIV agent;
antibacterial agent;
antifungal agent;
antimalarial;
antineoplastic agent;
metabolite		00low000000
2-acetamidoglucal
0
acetamides;
glycal derivative		metabolite00low000000
diorcinol
0
aromatic ether;
phenols		fungal metabolite;
marine metabolite;
metabolite		00low000000
caribenol a
0
organic heterotetracyclic compound;
terpene lactone;
tertiary alcohol		antimalarial;
antitubercular agent;
metabolite		00low000000
halisulfate 1
0
organic molecular entitymetabolite00low000000
6-O-feruloylcatalpol
0
hydroxycinnamic acidmetabolite00low000000
grassypeptolide
0
cyclodepsipeptide;
macrocycle		antineoplastic agent;
metabolite		00low000000
essramycin
0
triazolopyrimidinesmetabolite00low000000
ainsliadimer a
0
sesquiterpene lactone;
spiro compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
metabolite		00low000000
salvileucalin b
0
bridged compound;
diterpenoid;
furans;
gamma-lactone		antineoplastic agent;
metabolite		00low000000
ciliatamide a
0
caprolactams;
lipopeptide		antileishmanial agent;
metabolite		00low000000
etnangien
0
hydroxy monocarboxylic acid;
macrolide antibiotic		antibacterial agent;
metabolite		00low000000
latrunculol a
0
macrolidemetabolite00low000000
N-trans-sinapoyltyramine
0
hydroxycinnamic acidmetabolite00low000000
lycojapodine a
0
alkaloid;
bridged compound;
cyclic ketone;
lactone;
organic heterotetracyclic compound		anti-HIV-1 agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite		00low000000
epi-maslinic acid
0
dihydroxy monocarboxylic acid;
pentacyclic triterpenoid		anti-inflammatory agent;
metabolite		00low000000
eoxin c4
0
eoxin;
leukotriene		metabolite00low000000
brartemicin
0
benzoate ester;
glycosyl glycoside derivative;
resorcinols		antimicrobial agent;
metabolite		00low000000
Majusculamide AB
0
amino acid amidemetabolite00low000000
7,8-dihydroxyflavanone
0
dihydroxyflavanoneantineoplastic agent;
metabolite		00low000000
antcin a
0
ergostanoidmetabolite00low000000
integric acid
0
carboxylic ester;
cyclic ketone;
dioxo monocarboxylic acid;
enal;
enone;
eremophilane sesquiterpenoid		HIV-1 integrase inhibitor;
metabolite		00low000000
vanilloloside
0
glycosidemetabolite00low000000
2,3-dihydro-3beta-O-sulfate withaferin A
0
27-hydroxy steroid;
4-hydroxy steroid;
delta-lactone;
epoxy steroid;
ergostanoid;
primary alcohol;
steroid sulfate;
withanolide		antineoplastic agent;
metabolite;
plant metabolite		00low000000
dicranin
0
acetylenic fatty acid;
long-chain fatty acid;
straight-chain fatty acid;
trienoic fatty acid		antibacterial agent;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
metabolite		00low000000
leachianone a
0
4'-hydroxyflavanones;
monomethoxyflavanone;
trihydroxyflavanone		antimalarial;
antineoplastic agent;
metabolite		00low000000
hordatine a
0
aromatic ether;
benzofurans;
dicarboxylic acid diamide;
guanidines;
phenols		adrenergic antagonist;
metabolite		00low000000
englerin a
0
cinnamate ester;
glycolate ester;
guaiane sesquiterpenoid		antineoplastic agent;
metabolite		00low000000
monanchocidin
0
organic molecular entitymetabolite00low000000
eurycomanone
0
cyclic ether;
delta-lactone;
enone;
organic heteropentacyclic compound;
pentol;
quassinoid;
secondary alcohol;
secondary alpha-hydroxy ketone;
tertiary alcohol		antimalarial;
antineoplastic agent;
metabolite		00low000000
sphaeropsidin a
0
gamma-lactonemetabolite00low000000
gardenoside
0
beta-D-glucoside;
cyclopentapyran;
enoate ester;
methyl ester;
monosaccharide derivative;
tertiary alcohol		metabolite00low000000
landomycin d
0
anthraquinonemetabolite00low000000
3alpha,12alpha-dihydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acid
0
11-oxo steroid;
12alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7-oxo steroid;
monocarboxylic acid;
secondary alpha-hydroxy ketone;
steroid acid		antineoplastic agent;
metabolite		00low000000
antcin k
0
bile acidmetabolite00low000000
3alpha-hydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acid
0
11-oxo steroid;
3alpha-hydroxy steroid;
7-oxo steroid;
monocarboxylic acid;
steroid acid		antineoplastic agent;
cholinergic antagonist;
metabolite;
serotonergic antagonist		00low000000
shizukaol B
0
triterpenoidmetabolite00low000000
shizukaol f
0
triterpenoidmetabolite00low000000
calicheamicin gamma(1)i
0
calicheamicin;
enediyne antibiotic;
organoiodine compound		antineoplastic agent;
metabolite		00low000000
staphyloxanthin
0
apo carotenoid triterpenoid;
D-aldohexose derivative;
fatty acid ester;
triol;
xanthophyll		antioxidant;
biological pigment;
metabolite;
virulence factor		00low000000
sm 1 peptide
0
acetate ester;
ergot alkaloid		metabolite00low000000
mycocyclosin
0
2,5-diketopiperazines;
organic heterotetracyclic compound;
polyphenol		metabolite00low000000
callipeltin a
0
cyclodepsipeptide;
guanidines;
lactone;
oligopeptide;
phenols		anti-HIV-1 agent;
antifungal agent;
metabolite		00low000000
vinylamycin
0
cyclodepsipeptide;
macrocycle;
primary alcohol		antibacterial agent;
antimicrobial agent;
metabolite		00low000000
promegestone
0
terpene lactonemetabolite00low000000
lancifodilactone g
0
cyclic ether;
diol;
enol;
gamma-lactone;
oxaspiro compound;
triterpenoid		anti-HIV agent;
metabolite		00low000000
rediocide a
0
diterpenoid;
epoxide;
ortho ester;
terpene lactone		insecticide;
metabolite		00low000000
lasiokaurin
0
kaurane diterpenoidmetabolite00low000000
longikaurin a
0
kaurane diterpenoidmetabolite00low000000
ponicidin
0
dioxanesmetabolite00low000000
(Z)-6,6',7,3'a-Diligustilide
0
butenolidemetabolite00low000000
suvanine
0
organic molecular entitymetabolite00low000000
shizukaol d
0
triterpenoidmetabolite00low000000
thailandepsin a
0
cyclodepsipeptidemetabolite00low000000
nordidemnin b
0
didemninmetabolite00low000000
4-formylaminooxyvinylglycine
0
non-proteinogenic alpha-amino acidmetabolite00low000000
platycoside e
0
triterpenoid saponinmetabolite00low000000
leuconoxine
0
alkaloidmetabolite00low000000
epidermin
0
macrocycle;
type A lantibiotic		antibacterial agent;
metabolite		00low000000
surfactin A
0
cyclodepsipeptide;
lipopeptide antibiotic;
macrocyclic lactone		antibacterial agent;
antifungal agent;
antineoplastic agent;
antiviral agent;
metabolite;
surfactant		00low000000
myriaporone 3
0
beta-hydroxy ketone;
epoxide;
lactol;
oxanes;
primary alcohol;
secondary alcohol		antineoplastic agent;
metabolite		00low000000
avenacoside b
0
beta-D-glucoside;
hexacyclic triterpenoid;
spiroketal;
steroid saponin;
tetrasaccharide derivative		metabolite00low000000
3-methylglutarylcarnitine
0
O-methylglutarylcarnitinemetabolite00low000000
pivaloylcarnitine
0
C5-acylcarnitinemetabolite00low000000
levoleucovorin
0
5-formyltetrahydrofolic acidantineoplastic agent;
metabolite		00low000000
7,8-dihydroneopterin
0
dihydropterin;
neopterins		Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		00low000000
guanosine monophosphate
0
guanosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		biomarker;
Escherichia coli metabolite;
metabolite;
mouse metabolite		00low000000
2-amino-4-oxo-6-acetyl-7,8-dihydro-3h,9h-pyrimidodiazepine
0
methyl ketone;
pyrimidodiazepine		metabolite00low000000
dyspropterin
0
biopterins;
tetrahydropterin		human metabolite;
metabolite;
mouse metabolite		00low000000
2'-o-methylguanosine
0
methylguanosinemetabolite00low000000
allopurinol riboside
0
nucleoside analoguemetabolite00low000000
norclozapine
0
dibenzodiazepine;
organochlorine compound;
piperazines		delta-opioid receptor agonist;
metabolite;
serotonergic antagonist		00low000000
7-methylguanosine
0
methylguanosine;
organic cation		metabolite00low000000
3'-o-methylguanosine
0
methylguanosinemetabolite00low000000
primapterin
0
biopterinsmetabolite00low000000
7-methylinosine
0
inosines;
organic cation		metabolite00low000000
marineosin a
0
azaspiro compound;
ether;
macrocycle;
oxaspiro compound;
pyrroles		antineoplastic agent;
metabolite		00low000000
marineosin b
0
azaspiro compound;
ether;
macrocycle;
oxaspiro compound;
pyrroles		antineoplastic agent;
metabolite		00low000000
gallic acid
0
trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite		00low000000
dihydrolipoic acid
0
thio-fatty acidantioxidant;
human metabolite;
neuroprotective agent		00low000000
hydrogen
0
elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite		00low000000
hydroquinone
0
benzenediol;
hydroquinones		antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent		00low000000
n-acetylserotonin
0
acetamides;
N-acylserotonin;
phenols		antioxidant;
human metabolite;
mouse metabolite;
tropomyosin-related kinase B receptor agonist		00low000000
pqq cofactor
0
orthoquinones;
pyrroloquinoline cofactor;
tricarboxylic acid		anti-inflammatory agent;
antioxidant;
cofactor;
water-soluble vitamin (role)		00low000000
putrescine
0
alkane-alpha,omega-diamineantioxidant;
fundamental metabolite		00low000000
spermine
0
polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent		00low000000
taurine
0
amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite		00low000000
vanillin
0
benzaldehydes;
monomethoxybenzene;
phenols		anti-inflammatory agent;
anticonvulsant;
antioxidant;
flavouring agent;
plant metabolite		00low000000
isopentenyl pyrophosphate
0
prenol phosphateantigen;
antioxidant;
epitope;
Escherichia coli metabolite;
mouse metabolite;
phosphoantigen		00low000000
5-methoxytryptamine
0
aromatic ether;
primary amino compound;
tryptamines		5-hydroxytryptamine 2A receptor agonist;
5-hydroxytryptamine 2B receptor agonist;
5-hydroxytryptamine 2C receptor agonist;
antioxidant;
cardioprotective agent;
human metabolite;
mouse metabolite;
neuroprotective agent;
radiation protective agent;
serotonergic agonist		00low000000
7,8-dihydroxyflavone
0
dihydroxyflavoneantidepressant;
antineoplastic agent;
antioxidant;
plant metabolite;
tropomyosin-related kinase B receptor agonist		00low000000
amifostine anhydrous
0
diamine;
organic thiophosphate		antioxidant;
prodrug;
radiation protective agent		00low000000
benphothiamine
0
aminopyrimidine;
formamides;
organic phosphate;
thioester		antioxidant;
immunological adjuvant;
nutraceutical;
protective agent;
provitamin B1		00low000000
caffeic acid
0
catechols;
hydroxycinnamic acid		antioxidant;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
plant metabolite		00low000000
carcinine
0
beta-alanine derivative;
imidazoles;
monocarboxylic acid amide;
organonitrogen compound;
organooxygen compound		antioxidant;
crustacean metabolite		00low000000
ebselen
0
benzoselenazoleanti-inflammatory drug;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 3.5.4.1 (cytosine deaminase) inhibitor;
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor;
enzyme mimic;
ferroptosis inhibitor;
genotoxin;
hepatoprotective agent;
neuroprotective agent;
radical scavenger		00low000000
idebenone
0
1,4-benzoquinones;
primary alcohol		antioxidant;
ferroptosis inhibitor		00low000000
edaravone
0
pyrazoloneantioxidant;
radical scavenger		00low000000
molsidomine
0
ethyl ester;
morpholines;
oxadiazole;
zwitterion		antioxidant;
apoptosis inhibitor;
cardioprotective agent;
nitric oxide donor;
vasodilator agent		00low000000
masoprocol
0
catechols;
lignan;
tetrol		antioxidant;
ferroptosis inhibitor;
geroprotector;
plant metabolite		00low000000
probucol
0
dithioketal;
polyphenol		anti-inflammatory drug;
anticholesteremic drug;
antilipemic drug;
antioxidant;
cardiovascular drug		00low000000
resveratrol
0
polyphenol;
resorcinols;
stilbenol		antioxidant;
geroprotector;
glioma-associated oncogene inhibitor;
phytoalexin		00low000000
sulforaphane
0
isothiocyanate;
sulfoxide		antineoplastic agent;
antioxidant;
EC 3.5.1.98 (histone deacetylase) inhibitor;
plant metabolite		00low000000
troglitazone
0
chromanes;
thiazolidinone		anticoagulant;
anticonvulsant;
antineoplastic agent;
antioxidant;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
hypoglycemic agent;
platelet aggregation inhibitor;
vasodilator agent		00low000000
zonisamide
0
1,2-benzoxazoles;
sulfonamide		anticonvulsant;
antioxidant;
central nervous system drug;
protective agent;
T-type calcium channel blocker		00low000000
phlorhizin
0
aryl beta-D-glucoside;
dihydrochalcones;
monosaccharide derivative		antioxidant;
plant metabolite		00low000000
methylene blue
0
organic chloride saltacid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer		00low000000
medroxyprogesterone acetate
0
20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
corticosteroid;
steroid ester		adjuvant;
androgen;
antineoplastic agent;
antioxidant;
female contraceptive drug;
inhibitor;
progestin;
synthetic oral contraceptive		00low000000
n,n'-diphenyl-4-phenylenediamine
0
N-substituted diamine;
secondary amino compound		antioxidant00low000000
2,4-di-tert-butylphenol
0
alkylbenzene;
phenols		antioxidant;
bacterial metabolite;
marine metabolite		00low000000
lactobionic acid
0
disaccharideantioxidant00low000000
methyl gallate
0
gallate esteranti-inflammatory agent;
antioxidant;
plant metabolite		00low000000
gamma-terpinene
0
cyclohexadiene;
monoterpene		antioxidant;
human xenobiotic metabolite;
plant metabolite;
volatile oil component		00low000000
n-isopropyl-n-phenyl-4-phenylenediamine
0
N-substituted diamineallergen;
antioxidant		00low000000
3-tert-butyl-4-hydroxyanisole
0
aromatic ether;
phenols		antioxidant;
human xenobiotic metabolite		00low000000
ethyl vanillin
0
aromatic ether;
benzaldehydes;
phenols		antioxidant;
flavouring agent		00low000000
catechin
0
catechinantioxidant;
plant metabolite		00low000000
triethylenediamine
0
bridged compound;
diamine;
saturated organic heterobicyclic parent;
tertiary amino compound		antioxidant;
catalyst;
reagent		00low000000
thiazolidine-4-carboxylic acid
0
alpha-amino acid zwitterion;
non-proteinogenic alpha-amino acid;
sulfur-containing amino acid;
thiazolidinemonocarboxylic acid		antidote;
antioxidant;
hepatoprotective agent		00low000000
4-methylcatechol
0
methylcatecholantioxidant;
carcinogenic agent;
hapten;
human metabolite;
plant metabolite		00low000000
thymoquinone
0
1,4-benzoquinonesadjuvant;
anti-inflammatory agent;
antidepressant;
antineoplastic agent;
antioxidant;
cardioprotective agent;
plant metabolite		00low000000
4-hydroxyphenylethanol
0
phenolsanti-arrhythmia drug;
antioxidant;
cardiovascular drug;
fungal metabolite;
geroprotector;
plant metabolite;
protective agent		00low000000
4-methyl-1-(1-methylethyl)-3-cyclohexen-1-ol
0
terpineol;
tertiary alcohol		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiparasitic agent;
apoptosis inducer;
plant metabolite;
volatile oil component		00low000000
diphenylamine
0
aromatic amine;
bridged diphenyl fungicide;
secondary amino compound		antifungal agrochemical;
antioxidant;
carotogenesis inhibitor;
EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor;
ferroptosis inhibitor;
radical scavenger		00low000000
acetylcysteine
0
acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary		00low000000
dihydroferulic acid
0
guaiacols;
monocarboxylic acid;
phenylpropanoid		antioxidant;
human xenobiotic metabolite;
mouse metabolite;
plant metabolite		00low000000
d-alpha tocopherol
0
alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite		00low000000
diallyl trisulfide
0
organic trisulfideanti-inflammatory agent;
antilipemic drug;
antineoplastic agent;
antioxidant;
antiprotozoal drug;
apoptosis inducer;
estrogen receptor antagonist;
insecticide;
platelet aggregation inhibitor;
vasodilator agent		00low000000
methyl vanillate
0
aromatic ether;
benzoate ester;
phenols		antioxidant;
plant metabolite		00low000000
zingerone
0
methyl ketone;
monomethoxybenzene;
phenols		anti-inflammatory agent;
antiemetic;
antioxidant;
flavouring agent;
fragrance;
plant metabolite;
radiation protective agent		00low000000
butylated hydroxytoluene
0
phenolsantioxidant;
ferroptosis inhibitor;
food additive;
geroprotector		00low000000
2,6-di-tert-butylphenol
0
alkylbenzene;
phenols		antioxidant00low000000
silybin
0
aromatic ether;
benzodioxine;
flavonolignan;
polyphenol;
secondary alpha-hydroxy ketone		antineoplastic agent;
antioxidant;
hepatoprotective agent;
plant metabolite		00low000000
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
0
chromanol;
monocarboxylic acid;
phenols		antioxidant;
ferroptosis inhibitor;
neuroprotective agent;
radical scavenger;
Wnt signalling inhibitor		00low000000
oltipraz
0
1,2-dithiole;
pyrazines		angiogenesis modulating agent;
antimutagen;
antineoplastic agent;
antioxidant;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
neurotoxin;
protective agent;
schistosomicide drug		00low000000
baicalin
0
dihydroxyflavone;
glucosiduronic acid;
glycosyloxyflavone;
monosaccharide derivative		antiatherosclerotic agent;
antibacterial agent;
anticoronaviral agent;
antineoplastic agent;
antioxidant;
cardioprotective agent;
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
ferroptosis inhibitor;
neuroprotective agent;
non-steroidal anti-inflammatory drug;
plant metabolite;
prodrug		00low000000
epigallocatechin gallate
0
flavans;
gallate ester;
polyphenol		antineoplastic agent;
antioxidant;
apoptosis inducer;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent;
plant metabolite		00low000000
n-acetylaspartic acid
0
N-acetyl-L-amino acid;
N-acyl-L-aspartic acid		antioxidant;
human metabolite;
mouse metabolite;
nutraceutical;
rat metabolite		00low000000
salvin
0
abietane diterpenoid;
carbotricyclic compound;
catechols;
monocarboxylic acid		angiogenesis modulating agent;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
food preservative;
HIV protease inhibitor;
plant metabolite		00low000000
7-hydroxydehydroepiandrosterone
0
17-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
7alpha-hydroxy steroid;
androstanoid		anti-inflammatory agent;
antioxidant;
estrogen;
human xenobiotic metabolite;
rat metabolite		00low000000
epicatechin
0
catechin;
polyphenol		antioxidant00low000000
gallocatechol
0
catechin;
flavan-3,3',4',5,5',7-hexol		antioxidant;
food component;
plant metabolite		00low000000
hesperetin
0
3'-hydroxyflavanones;
4'-methoxyflavanones;
monomethoxyflavanone;
trihydroxyflavanone		antineoplastic agent;
antioxidant;
plant metabolite		00low000000
vexibinol
0
(2S)-flavan-4-one;
4'-hydroxyflavanones;
tetrahydroxyflavanone		antimalarial;
antimicrobial agent;
antioxidant;
plant metabolite		00low000000
brazilin
0
catechols;
organic heterotetracyclic compound;
tertiary alcohol		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
biological pigment;
hepatoprotective agent;
histological dye;
NF-kappaB inhibitor;
plant metabolite		00low000000
madecassic acid
0
monocarboxylic acid;
pentacyclic triterpenoid;
tetrol		antioxidant;
plant metabolite		00low000000
fangchinoline
0
aromatic ether;
bisbenzylisoquinoline alkaloid;
macrocycle		anti-HIV-1 agent;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
neuroprotective agent;
plant metabolite		00low000000
corilagin
0
ellagitannin;
gallate ester		antihypertensive agent;
antioxidant;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
non-steroidal anti-inflammatory drug		00low000000
maslinic acid
0
dihydroxy monocarboxylic acid;
pentacyclic triterpenoid		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
plant metabolite		00low000000
ethyl protocatechuate
0
catechols;
ethyl ester		antibacterial agent;
antioxidant;
apoptosis inducer;
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
plant metabolite		00low000000
decane-1,2-diol
0
glycol;
volatile organic compound		anti-inflammatory agent;
antioxidant;
human metabolite		00low000000
eriocitrin
0
3'-hydroxyflavanones;
4'-hydroxyflavanones;
disaccharide derivative;
flavanone glycoside;
rutinoside;
trihydroxyflavanone		antioxidant00low000000
3,4-dihydroxymandelic acid
0
2-hydroxy monocarboxylic acid;
catechols		antioxidant;
drug metabolite;
human metabolite;
mouse metabolite		00low000000
sugiol
0
abietane diterpenoid;
carbotricyclic compound;
cyclic terpene ketone;
meroterpenoid;
phenols		antineoplastic agent;
antioxidant;
antiviral agent;
plant metabolite;
radical scavenger		00low000000
sesaminol
0
benzodioxoles;
furofuran;
organic hydroxy compound		antioxidant;
plant metabolite		00low000000
wr 1065
0
alkanethiol;
diamine		antioxidant;
drug metabolite;
radiation protective agent		00low000000
cafestol
0
diterpenoid;
furans;
organic heteropentacyclic compound;
primary alcohol;
tertiary alcohol		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
hypoglycemic agent;
plant metabolite		00low000000
kahweol
0
diterpenoid;
furans;
organic heteropentacyclic compound;
primary alcohol;
tertiary alcohol		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
plant metabolite		00low000000
swertisin
0
dihydroxyflavone;
flavone C-glycoside;
monomethoxyflavone;
monosaccharide derivative;
polyphenol		adenosine A1 receptor antagonist;
anti-inflammatory agent;
antioxidant;
hypoglycemic agent;
plant metabolite		00low000000
rubiadin
0
dihydroxyanthraquinoneantibacterial agent;
antioxidant;
hepatoprotective agent;
plant metabolite		00low000000
ovothiol c
0
aryl thiol;
L-alpha-amino acid zwitterion;
L-histidine derivative		antioxidant;
marine metabolite;
radical scavenger		00low000000
ovothiol a
0
aryl thiol;
L-alpha-amino acid zwitterion;
L-histidine derivative;
non-proteinogenic L-alpha-amino acid		antioxidant;
marine metabolite;
radical scavenger		00low000000
2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman
0
benzopyranantioxidant00low000000
schizandrin b
0
aromatic ether;
cyclic acetal;
organic heterotetracyclic compound;
oxacycle;
tannin		anti-asthmatic agent;
anti-inflammatory agent;
antilipemic drug;
antioxidant;
apoptosis inhibitor;
hepatoprotective agent;
nephroprotective agent;
neuroprotective agent;
plant metabolite		00low000000
acrovestone
0
acetophenones;
aromatic ether;
olefinic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite		00low000000
4'-demethyldesoxypodophyllotoxin
0
furonaphthodioxole;
gamma-lactone;
lignan;
methoxybenzenes;
phenols		antineoplastic agent;
antioxidant;
immunosuppressive agent;
plant metabolite		00low000000
secoxyloganin
0
beta-D-glucoside;
dicarboxylic acid monoester;
enoate ester;
methyl ester;
monosaccharide derivative;
pyrans;
secoiridoid glycoside		anti-allergic agent;
antioxidant;
plant metabolite		00low000000
pectolinarin
0
dimethoxyflavone;
disaccharide derivative;
glycosyloxyflavone;
monohydroxyflavanone;
rutinoside		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
plant metabolite		00low000000
2,5-dihydroxybenzyl alcohol
0
aromatic primary alcohol;
phenols		antineoplastic agent;
antioxidant;
apoptosis inhibitor;
fungal metabolite		00low000000
sitosterol, (3beta)-isomer
0
3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
C29-steroid;
phytosterols;
stigmastane sterol		anticholesteremic drug;
antioxidant;
mouse metabolite;
plant metabolite;
sterol methyltransferase inhibitor		00low000000
erythritol
0
butane-1,2,3,4-tetrolantioxidant;
human metabolite;
plant metabolite		00low000000
methyl 3,4-dihydroxybenzoate
0
catechols;
methyl ester		antioxidant;
neuroprotective agent;
plant metabolite		00low000000
sorbinil
0
azaspiro compound;
chromanes;
imidazolidinone;
organofluorine compound;
oxaspiro compound		antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor		00low000000
3,4-dihydroxyphenylpropionic acid
0
(dihydroxyphenyl)propanoic acidantioxidant;
human xenobiotic metabolite		00low000000
n-acetylneuraminic acid
0
N-acetylneuraminic acidsantioxidant;
bacterial metabolite;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
human metabolite;
mouse metabolite		00low000000
carnosine
0
amino acid zwitterion;
dipeptide		anticonvulsant;
antineoplastic agent;
antioxidant;
Daphnia magna metabolite;
geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent		00low000000
allose
0
allopyranose;
D-allose		antioxidant00low000000
ginsenoside re
0
12beta-hydroxy steroid;
3beta-hydroxy-4,4-dimethylsteroid;
3beta-hydroxy steroid;
beta-D-glucoside;
disaccharide derivative;
ginsenoside;
tetracyclic triterpenoid		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
nephroprotective agent;
neuroprotective agent;
plant metabolite		00low000000
notoginsenoside r1
0
12beta-hydroxy steroid;
3beta-hydroxy-4,4-dimethylsteroid;
3beta-hydroxy steroid;
beta-D-glucoside;
disaccharide derivative;
ginsenoside;
tetracyclic triterpenoid		antioxidant;
apoptosis inducer;
neuroprotective agent;
phytoestrogen;
plant metabolite		00low000000
stevioside
0
beta-D-glucoside;
bridged compound;
diterpene glycoside;
ent-kaurane diterpenoid;
tetracyclic diterpenoid		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
hypoglycemic agent;
plant metabolite;
sweetening agent		00low000000
genipin
0
iridoid monoterpenoidanti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cross-linking reagent;
hepatotoxic agent;
uncoupling protein inhibitor		00low000000
solasodine
0
alkaloid antibiotic;
azaspiro compound;
hemiaminal ether;
oxaspiro compound;
sapogenin;
steroid alkaloid		anticonvulsant;
antifungal agent;
antiinfective agent;
antioxidant;
antipyretic;
antispermatogenic agent;
apoptosis inducer;
cardiotonic drug;
central nervous system depressant;
diuretic;
immunomodulator;
plant metabolite;
teratogenic agent		00low000000
tretinoin
0
retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule		00low000000
equilenin
0
17-oxo steroid;
3-hydroxy steroid		antioxidant;
mammalian metabolite		00low000000
resveratrol
0
resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger		00low000000
oleic acid
0
octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent		00low000000
ferulic acid
0
ferulic acidsanti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
MALDI matrix material;
plant metabolite		00low000000
lycopene
0
acyclic caroteneantioxidant;
plant metabolite		00low000000
pallidol
0
carbopolycyclic compound;
polyphenol;
stilbenoid		antifungal agent;
antioxidant;
plant metabolite		00low000000
riboflavin
0
flavin;
vitamin B2		anti-inflammatory agent;
antioxidant;
cofactor;
Escherichia coli metabolite;
food colouring;
fundamental metabolite;
human urinary metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite		00low000000
piperlactam s
0
alkaloid;
aromatic ether;
gamma-lactam;
organic heterotetracyclic compound;
phenols		anti-inflammatory agent;
antioxidant;
plant metabolite		00low000000
beta-ionone
0
iononeantioxidant;
fragrance		00low000000
propylthiouracil
0
pyrimidinethioneantidote to paracetamol poisoning;
antimetabolite;
antioxidant;
antithyroid drug;
carcinogenic agent;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
hormone antagonist		00low000000
aurapten
0
coumarins;
monoterpenoid		antihypertensive agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
dopaminergic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
gamma-secretase modulator;
gastrointestinal drug;
hepatoprotective agent;
matrix metalloproteinase inhibitor;
neuroprotective agent;
plant metabolite;
PPARalpha agonist;
vulnerary		00low000000
thiourea
0
one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore		00low000000
u 0126
0
aryl sulfide;
dinitrile;
enamine;
substituted aniline		antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
osteogenesis regulator;
vasoconstrictor agent		00low000000
ferrostatin-1
0
ethyl ester;
primary arylamine;
substituted aniline		antifungal agent;
antioxidant;
ferroptosis inhibitor;
neuroprotective agent;
radiation protective agent;
radical scavenger		00low000000
sb 415286
0
C-nitro compound;
maleimides;
monochlorobenzenes;
phenols;
secondary amino compound;
substituted aniline		antioxidant;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent		00low000000
fraxetin
0
aromatic ether;
hydroxycoumarin		anti-inflammatory agent;
antibacterial agent;
antimicrobial agent;
antioxidant;
apoptosis inducer;
apoptosis inhibitor;
Arabidopsis thaliana metabolite;
hepatoprotective agent;
hypoglycemic agent		00low000000
quercetin
0
7-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger		00low000000
bilirubin
0
biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite		00low000000
sinapine
0
acylcholineantioxidant;
photosynthetic electron-transport chain inhibitor;
plant metabolite		00low000000
quercitrin
0
alpha-L-rhamnoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		antileishmanial agent;
antioxidant;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite		00low000000
ubiquinone 9
0
ubiquinonesantioxidant;
human metabolite		00low000000
beta carotene
0
carotenoid beta-end derivative;
cyclic carotene		antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A		00low000000
retinol palmitate
0
all-trans-retinyl ester;
retinyl palmitate		antioxidant;
Escherichia coli metabolite;
human xenobiotic metabolite		00low000000
luteolin-7-glucoside
0
beta-D-glucoside;
glycosyloxyflavone;
monosaccharide derivative;
trihydroxyflavone		antioxidant;
plant metabolite		00low000000
quercetin 3-o-glucopyranoside
0
beta-D-glucoside;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antineoplastic agent;
antioxidant;
antipruritic drug;
bone density conservation agent;
geroprotector;
histamine antagonist;
osteogenesis regulator;
plant metabolite		00low000000
zeaxanthin
0
carotenolantioxidant;
bacterial metabolite;
cofactor		00low000000
butein
0
chalcones;
polyphenol		antineoplastic agent;
antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
geroprotector;
hypoglycemic agent;
plant metabolite;
radiosensitizing agent;
tyrosine kinase inhibitor		00low000000
astaxanthine
0
carotenol;
carotenone		animal metabolite;
anticoagulant;
antioxidant;
food colouring;
plant metabolite		00low000000
gardenia yellow
0
diester;
disaccharide derivative;
diterpenoid		antioxidant;
food colouring;
histological dye;
plant metabolite		00low000000
cryptoxanthins
0
carotenolantioxidant;
biomarker;
plant metabolite;
provitamin A		00low000000
esculetin
0
hydroxycoumarinantioxidant;
plant metabolite;
ultraviolet filter		00low000000
oleuropein
0
beta-D-glucoside;
catechols;
diester;
methyl ester;
pyrans;
secoiridoid glycoside		anti-inflammatory agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
NF-kappaB inhibitor;
nutraceutical;
plant metabolite;
radical scavenger		00low000000
baicalein
0
trihydroxyflavoneangiogenesis inhibitor;
anti-inflammatory agent;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 4.1.1.17 (ornithine decarboxylase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hormone antagonist;
plant metabolite;
prostaglandin antagonist;
radical scavenger		00low000000
chrysin
0
7-hydroxyflavonol;
dihydroxyflavone		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
EC 2.7.11.18 (myosin-light-chain kinase) inhibitor;
hepatoprotective agent;
plant metabolite		00low000000
diosmetin
0
3'-hydroxyflavonoid;
monomethoxyflavone;
trihydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
bone density conservation agent;
cardioprotective agent;
plant metabolite;
tropomyosin-related kinase B receptor agonist;
vasodilator agent		00low000000
diosmin
0
dihydroxyflavanone;
disaccharide derivative;
glycosyloxyflavone;
monomethoxyflavone;
rutinoside		anti-inflammatory agent;
antioxidant		00low000000
hispidulin
0
monomethoxyflavone;
trihydroxyflavone		anti-inflammatory agent;
anticonvulsant;
antineoplastic agent;
antioxidant;
apoptosis inducer;
plant metabolite		00low000000
mangiferin
0
C-glycosyl compound;
xanthones		anti-inflammatory agent;
antioxidant;
hypoglycemic agent;
plant metabolite		00low000000
mangostin
0
aromatic ether;
phenols;
xanthones		antimicrobial agent;
antineoplastic agent;
antioxidant;
plant metabolite		00low000000
1,2,8-trihydroxy-6-methoxyxanthone
0
aromatic ether;
polyphenol;
xanthones		antioxidant;
plant metabolite		00low000000
myricetin
0
7-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite		00low000000
quercetagetin
0
flavonols;
hexahydroxyflavone		antioxidant;
antiviral agent;
plant metabolite		00low000000
coumestrol
0
coumestans;
delta-lactone;
polyphenol		anti-inflammatory agent;
antioxidant;
plant metabolite		00low000000
pterostilbene
0
diether;
methoxybenzenes;
stilbenol		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
hypoglycemic agent;
neuroprotective agent;
neurotransmitter;
plant metabolite;
radical scavenger		00low000000
ellagic acid
0
catechols;
cyclic ketone;
lactone;
organic heterotetracyclic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor;
EC 2.4.1.1 (glycogen phosphorylase) inhibitor;
EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor;
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor;
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
food additive;
fungal metabolite;
geroprotector;
plant metabolite;
skin lightening agent		00low000000
coenzyme q10
0
ubiquinonesantioxidant;
ferroptosis inhibitor;
human metabolite		00low000000
quercetin-3-o-sophoroside
0
sophoroside;
tetrahydroxyflavone		antioxidant;
plant metabolite		00low000000
gamma-tocotrienol
0
tocotrienol;
vitamin E		antineoplastic agent;
antioxidant;
apoptosis inducer;
hepatoprotective agent;
plant metabolite;
radiation protective agent		00low000000
menatetrenone
0
menaquinoneanti-inflammatory agent;
antioxidant;
bone density conservation agent;
human metabolite;
neuroprotective agent		00low000000
nk 104
0
calcium salt;
statin (synthetic)		antioxidant00low000000
pitavastatin
0
cyclopropanes;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
quinolines;
statin (synthetic)		antioxidant00low000000
fenretinide
0
monocarboxylic acid amide;
retinoid		antineoplastic agent;
antioxidant		00low000000
rosmarinic acid
0
carboxylic ester;
monocarboxylic acid;
phenylpropanoid;
polyphenol		antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug;
plant metabolite;
serine proteinase inhibitor		00low000000
cannabigerol
0
phytocannabinoid;
resorcinols		anti-inflammatory agent;
antibacterial agent;
antioxidant;
appetite enhancer;
cannabinoid receptor agonist;
neuroprotective agent;
plant metabolite		00low000000
quadrangularin a
0
indanes;
polyphenol;
stilbenoid		antioxidant;
plant metabolite		00low000000
isosalipurposide
0
beta-D-glucoside;
chalcones;
monosaccharide derivative;
resorcinols		antioxidant;
plant metabolite		00low000000
icariin
0
flavonols;
glycosyloxyflavone		antioxidant;
bone density conservation agent;
EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
phytoestrogen		00low000000
4-methylesculetin
0
hydroxycoumarinanti-inflammatory agent;
antioxidant;
hyaluronan synthesis inhibitor		00low000000
spiraeoside
0
beta-D-glucoside;
flavonols;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antineoplastic agent;
antioxidant;
plant metabolite		00low000000
(E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside
0
beta-D-glucoside;
resorcinols;
stilbenoid		anti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
cyclooxygenase 2 inhibitor;
platelet aggregation inhibitor		00low000000
ag-490
0
catechols;
enamide;
monocarboxylic acid amide;
nitrile;
secondary carboxamide		anti-inflammatory agent;
antioxidant;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector;
STAT3 inhibitor		00low000000
ergothioneine
0
1,3-dihydroimidazole-2-thiones;
amino-acid betaine;
L-histidine derivative;
sulfur-containing amino acid		antioxidant;
chelator;
fungal metabolite;
plant metabolite;
xenobiotic metabolite		00low000000
molsidomine
0
ethyl ester;
morpholines;
oxadiazole;
zwitterion		antioxidant;
apoptosis inhibitor;
cardioprotective agent;
nitric oxide donor;
vasodilator agent		00low000000
monomethyl fumarate
0
dicarboxylic acid monoester;
enoate ester;
methyl ester		antioxidant;
drug metabolite;
immunomodulator		00low000000
5,4'-dihydroxy-7,3'-dimethoxyflavone
0
dihydroxyflavone;
dimethoxyflavone		anti-allergic agent;
anti-inflammatory agent;
antibacterial agent;
antioxidant;
melanin synthesis inhibitor;
plant metabolite		00low000000
quercetin 3-sambubioside
0
disaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antioxidant;
plant metabolite		00low000000
germacrone
0
germacrane sesquiterpenoid;
olefinic compound		androgen antagonist;
anti-inflammatory agent;
antifeedant;
antifungal agent;
antimicrobial agent;
antineoplastic agent;
antioxidant;
antitussive;
antiviral agent;
apoptosis inducer;
autophagy inducer;
hepatoprotective agent;
insecticide;
neuroprotective agent;
plant metabolite;
volatile oil component		00low000000
meso-zeaxanthin
0
carotenolanti-inflammatory agent;
antioxidant;
human xenobiotic metabolite;
marine metabolite		00low000000
salvianolic acid B
0
1-benzofurans;
catechols;
dicarboxylic acid;
enoate ester;
polyphenol		anti-inflammatory agent;
antidepressant;
antineoplastic agent;
antioxidant;
apoptosis inducer;
autophagy inhibitor;
cardioprotective agent;
hepatoprotective agent;
hypoglycemic agent;
neuroprotective agent;
osteogenesis regulator;
plant metabolite		00low000000
trilobatin
0
aryl beta-D-glucoside;
dihydrochalcones;
monosaccharide derivative		anti-inflammatory agent;
antioxidant;
plant metabolite;
sweetening agent		00low000000
capsiate
0
carboxylic ester;
monomethoxybenzene;
phenols		angiogenesis inhibitor;
anti-allergic agent;
anti-inflammatory agent;
antioxidant;
capsaicin receptor agonist;
hypoglycemic agent;
plant metabolite		00low000000
tln 4601
0
dibenzodiazepine;
farnesane sesquiterpenoid;
olefinic compound;
secondary amine;
triol		antineoplastic agent;
antioxidant;
cathepsin L (EC 3.4.22.15) inhibitor		00low000000
arachidonoylserotonin
0
N-acylserotonin;
phenols		anti-inflammatory agent;
anticonvulsant;
antioxidant;
capsaicin receptor antagonist;
EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor;
human metabolite;
signalling molecule		00low000000
nigerloxin
0
aromatic ether;
benzamides;
benzoic acids;
phenols;
styrenes		antioxidant;
Aspergillus metabolite;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
lipoxygenase inhibitor;
radical scavenger		00low000000
aspalathin
0
C-glycosyl compound;
catechols;
dihydrochalcones;
polyketide;
polyphenol		antioxidant;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
hypoglycemic agent;
plant metabolite		00low000000
glyceryl ferulate
0
1-monoglyceride;
aromatic ether;
enoate ester;
phenols		antioxidant;
plant metabolite;
ultraviolet filter		00low000000
(+)-dehydrodiconiferyl alcohol
0
dehydrodiconiferyl alcoholantioxidant;
plant metabolite		00low000000
ginsenoside rb3
0
12beta-hydroxy steroid;
beta-D-glucoside;
disaccharide derivative;
ginsenoside;
tetracyclic triterpenoid		antidepressant;
antioxidant;
cardioprotective agent;
neuroprotective agent;
NMDA receptor antagonist;
plant metabolite		00low000000
astragaloside IV
0
pentacyclic triterpenoid;
triterpenoid saponin		anti-inflammatory agent;
antioxidant;
EC 4.2.1.1 (carbonic anhydrase) inhibitor;
neuroprotective agent;
plant metabolite;
pro-angiogenic agent		00low000000
1-O-feruloyl-beta-D-glucose
0
aromatic ether;
beta-D-glucoside;
cinnamate ester;
phenols		antioxidant;
plant metabolite		00low000000
pyranonigrin a
0
cyclic ketone;
enol;
gamma-lactam;
pyranopyrrole;
secondary alcohol		antioxidant;
Aspergillus metabolite;
marine metabolite		00low000000
madecassoside
0
carboxylic ester;
pentacyclic triterpenoid;
trisaccharide derivative;
triterpenoid saponin		anti-inflammatory agent;
antioxidant;
antirheumatic drug;
plant metabolite;
vulnerary		00low000000
bacillithiol
0
glycoside;
monosaccharide derivative;
thiol		antioxidant;
bacterial metabolite;
cofactor		00low000000
kurarinol
0
4'-hydroxyflavanones;
monomethoxyflavanone;
trihydroxyflavanone		anti-inflammatory agent;
antioxidant;
plant metabolite		00low000000
(20R)-ginsenoside Rg3
0
ginsenoside;
glycoside;
tetracyclic triterpenoid		antioxidant;
plant metabolite		00low000000
hispidin
0
2-pyranones;
catechols		antioxidant;
EC 2.7.11.13 (protein kinase C) inhibitor;
fungal metabolite		00low000000
oleuropein aglycone
0
catechols;
diester;
lactol;
methyl ester;
pyrans;
secoiridoid		anti-inflammatory agent;
antioxidant;
mTOR inhibitor;
neuroprotective agent;
plant metabolite;
TRPA1 channel agonist		00low000000
6-hydroxy-2,4,5-triaminopyrimidine
0
aminopyrimidine;
hydroxypyrimidine		antioxidant;
chromophore		00low000000
liproxstatin-1
0
azaspiro compound;
monochlorobenzenes;
organic heterotricyclic compound;
secondary amino compound		antioxidant;
cardioprotective agent;
ferroptosis inhibitor;
radical scavenger		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
pedalitin
0
monomethoxyflavone;
tetrahydroxyflavone		EC 1.17.3.2 (xanthine oxidase) inhibitor;
metabolite		00low000000
chrysoeriol
0
monomethoxyflavone;
trihydroxyflavone		antineoplastic agent;
antioxidant;
metabolite		00low000000
quercetin 3-o-methyl ether
0
monomethoxyflavone;
tetrahydroxyflavone		antimicrobial agent;
metabolite		00low000000
rutin
0
disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone		antioxidant;
metabolite		00low000000
fisetin
0
3'-hydroxyflavonoid;
7-hydroxyflavonol;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
metabolite;
plant metabolite		00low000000
genkwanin
0
dihydroxyflavone;
monomethoxyflavone		metabolite00low000000
3-methylquercetin
0
7-hydroxyflavonol;
monomethoxyflavone;
tetrahydroxyflavone		anticoagulant;
EC 1.14.18.1 (tyrosinase) inhibitor;
metabolite		00low000000
isoscutellarein
0
tetrahydroxyflavonemetabolite00low000000
kaempferide
0
7-hydroxyflavonol;
monomethoxyflavone;
trihydroxyflavone		antihypertensive agent;
metabolite		00low000000
morin
0
7-hydroxyflavonol;
pentahydroxyflavone		angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent		00low000000
orientin
0
3'-hydroxyflavonoid;
C-glycosyl compound;
tetrahydroxyflavone		antioxidant;
metabolite		00low000000
patuletin
0
flavonols;
monomethoxyflavone;
pentahydroxyflavone		analgesic;
antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
lipoxygenase inhibitor;
metabolite		00low000000
rhamnetin
0
monomethoxyflavone;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
metabolite		00low000000
scutellarein
0
tetrahydroxyflavonemetabolite00low000000
syringetin
0
3',5'-dimethoxyflavone;
3'-methoxyflavones;
7-hydroxyflavonol;
dimethoxyflavone;
tetrahydroxyflavone		metabolite;
platelet aggregation inhibitor		00low000000
quercimeritrin
0
beta-D-glucoside;
flavonols;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antioxidant;
metabolite		00low000000
isorhamnetin-3-o-galactoside
0
beta-D-galactoside;
glycosyloxyflavone;
monomethoxyflavone;
monosaccharide derivative;
trihydroxyflavone		metabolite00low000000
isorhamnetin 3-o-glucoside
0
beta-D-glucoside;
glycosyloxyflavone;
monomethoxyflavone;
monosaccharide derivative;
trihydroxyflavone		metabolite00low000000
artocarpin lectin
0
monomethoxyflavone;
trihydroxyflavone		antineoplastic agent;
metabolite		00low000000
quercetin 7-rhamnoside
0
alpha-L-rhamnoside;
flavonols;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		metabolite00low000000
swertisin
0
dihydroxyflavone;
flavone C-glycoside;
monomethoxyflavone;
monosaccharide derivative;
polyphenol		adenosine A1 receptor antagonist;
anti-inflammatory agent;
antioxidant;
hypoglycemic agent;
plant metabolite		00low000000
quercetin
0
7-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger		00low000000
quercitrin
0
alpha-L-rhamnoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		antileishmanial agent;
antioxidant;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite		00low000000
quercetin 3-o-glucopyranoside
0
beta-D-glucoside;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antineoplastic agent;
antioxidant;
antipruritic drug;
bone density conservation agent;
geroprotector;
histamine antagonist;
osteogenesis regulator;
plant metabolite		00low000000
chrysin
0
7-hydroxyflavonol;
dihydroxyflavone		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
EC 2.7.11.18 (myosin-light-chain kinase) inhibitor;
hepatoprotective agent;
plant metabolite		00low000000
diosmetin
0
3'-hydroxyflavonoid;
monomethoxyflavone;
trihydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
bone density conservation agent;
cardioprotective agent;
plant metabolite;
tropomyosin-related kinase B receptor agonist;
vasodilator agent		00low000000
diosmin
0
dihydroxyflavanone;
disaccharide derivative;
glycosyloxyflavone;
monomethoxyflavone;
rutinoside		anti-inflammatory agent;
antioxidant		00low000000
hispidulin
0
monomethoxyflavone;
trihydroxyflavone		anti-inflammatory agent;
anticonvulsant;
antineoplastic agent;
antioxidant;
apoptosis inducer;
plant metabolite		00low000000
myricetin
0
7-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite		00low000000
quercetin-3-o-sophoroside
0
sophoroside;
tetrahydroxyflavone		antioxidant;
plant metabolite		00low000000
spiraeoside
0
beta-D-glucoside;
flavonols;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antineoplastic agent;
antioxidant;
plant metabolite		00low000000
quercetin 3-sambubioside
0
disaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antioxidant;
plant metabolite		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
protocatechuic acid
1
catechols;
dihydroxybenzoic acid		antineoplastic agent;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
human xenobiotic metabolite;
plant metabolite		201820186.0low000010
coumarin
1
coumarinsfluorescent dye;
human metabolite;
plant metabolite		201820186.0low000010
gallic acid
1
trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite		2011201113.0low000010
4-aminophenol
1
aminophenolallergen;
metabolite		2012201212.0low000010
indoleacetic acid
1
indole-3-acetic acids;
monocarboxylic acid		auxin;
human metabolite;
mouse metabolite;
plant hormone;
plant metabolite		2012201212.0low000010
melatonin
1
acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger		2012201212.0low000010
orotic acid
1
pyrimidinemonocarboxylic acidEscherichia coli metabolite;
metabolite;
mouse metabolite		201820186.0low000010
epibatidine
1
alkaloid2012201212.0low000010
theophylline
1
dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent		2014201410.0low000010
aristolochic acid i
1
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin		2012201212.0low000010
5-methoxypsoralen
1
5-methoxyfurocoumarin;
organic heterotricyclic compound;
psoralens		hepatoprotective agent;
plant metabolite		2012201212.0low000010
chloroquine
1
aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug		2008200816.0low000100
2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone
1
1,4-benzoquinonescofactor2012201212.0low000010
3,3'-diindolylmethane
1
indolesantineoplastic agent;
P450 inhibitor		2012201212.0low000010
ellipticine
1
indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound;
polycyclic heteroarene		antineoplastic agent;
plant metabolite		2012201212.0low000010
embelin
1
dihydroxy-1,4-benzoquinonesantimicrobial agent;
antineoplastic agent;
hepatitis C protease inhibitor;
plant metabolite		2012201212.0low000010
emodin
1
trihydroxyanthraquinoneantineoplastic agent;
laxative;
plant metabolite;
tyrosine kinase inhibitor		2012201212.0low000010
gossypol
1
2012201212.0low000010
hypericin
1
2012201212.0low000010
indole-3-carbinol
1
indolyl alcoholantineoplastic agent;
plant metabolite		2012201212.0low000010
nsc 664704
1
indolobenzazepine;
lactam;
organobromine compound		cardioprotective agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
geroprotector		2012201212.0low000010
khellin
1
furanochromone;
organic heterotricyclic compound;
oxacycle		anti-asthmatic agent;
bronchodilator agent;
cardiovascular drug;
vasodilator agent		2012201212.0low000010
kinetin
1
6-aminopurines;
furans		cytokinin;
geroprotector		2012201212.0low000010
beta-lapachone
1
benzochromenone;
orthoquinones		anti-inflammatory agent;
antineoplastic agent;
plant metabolite		2012201212.0low000010
lavendustin a
1
aromatic amine2012201212.0low000010
lavendustin b
1
2012201212.0low000010
vitamin k 3
1
1,4-naphthoquinones;
vitamin K		angiogenesis inhibitor;
antineoplastic agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
human urinary metabolite;
nutraceutical		2012201212.0low000010
methoxsalen
1
aromatic ether;
psoralens		antineoplastic agent;
cross-linking reagent;
dermatologic drug;
photosensitizing agent;
plant metabolite		2012201212.0low000010
myristicin
1
organic molecular entitymetabolite2012201212.0low000010
nalidixic acid
1
1,8-naphthyridine derivative;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
DNA synthesis inhibitor		2012201212.0low000010
6,7-dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one
1
isoquinolines2012201212.0medium000010
patulin
1
furopyran;
gamma-lactone;
lactol		antimicrobial agent;
Aspergillus metabolite;
carcinogenic agent;
mutagen;
mycotoxin;
Penicillium metabolite		2012201212.0low000010
phloretin
2
dihydrochalconesantineoplastic agent;
plant metabolite		2012201510.5low000020
sanguinarine
1
alkaloid antibiotic;
benzophenanthridine alkaloid;
botanical anti-fungal agent		2012201212.0low000010
streptonigrin
1
pyridines;
quinolone		antimicrobial agent;
antineoplastic agent		2012201212.0low000010
tetrahydropapaverine
1
aromatic ether;
benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
polyether;
secondary amino compound		2012201212.0low000010
theobromine
1
dimethylxanthineadenosine receptor antagonist;
bronchodilator agent;
food component;
human blood serum metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent		2012201212.0low000010
trioxsalen
1
psoralensdermatologic drug;
photosensitizing agent		2012201212.0low000010
mitomycin
1
mitomycinalkylating agent;
antineoplastic agent		2012201212.0low000010
reserpine
1
alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic		2012201212.0low000010
pilocarpine hydrochloride
1
hydrochloride2012201212.0low000010
cantharidin
1
cyclic dicarboxylic anhydride;
monoterpenoid		EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
herbicide		2012201212.0low000010
physostigmine
1
carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic		2012201212.0low000010
kanamycin a
1
kanamycinsbacterial metabolite2012201212.0low000010
veratramine
1
piperidine alkaloid2012201212.0low000010
phlorhizin
1
aryl beta-D-glucoside;
dihydrochalcones;
monosaccharide derivative		antioxidant;
plant metabolite		2012201212.0low000010
papaverine hydrochloride
1
2012201212.0low000010
colchicine
1
alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen		2012201212.0low000010
yohimbine hydrochloride
1
2012201212.0low000010
cycloheximide
1
antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor		2012201212.0low000010
gliotoxin
1
dipeptide;
organic disulfide;
organic heterotetracyclic compound;
pyrazinoindole		antifungal agent;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor;
immunosuppressive agent;
mycotoxin;
proteasome inhibitor		2012201212.0low000010
tubercidin
1
antibiotic antifungal agent;
N-glycosylpyrrolopyrimidine;
ribonucleoside		antimetabolite;
antineoplastic agent;
bacterial metabolite		2012201212.0low000010
veratridine
1
steroidsodium channel modulator2012201212.0low000010
gibberellic acid
1
C19-gibberellin;
gibberellin monocarboxylic acid;
lactone;
organic heteropentacyclic compound		mouse metabolite;
plant metabolite		2012201212.0low000010
visnagin
1
aromatic ether;
furanochromone;
polyketide		anti-inflammatory agent;
antihypertensive agent;
EC 1.1.1.37 (malate dehydrogenase) inhibitor;
phytotoxin;
plant metabolite;
vasodilator agent		2012201212.0low000010
rotenone
1
organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin		2012201212.0low000010
skimmianine
1
alkaloid antibiotic;
organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle		2012201212.0low000010
syrosingopine
1
yohimban alkaloid2012201212.0low000010
gramine
1
aminoalkylindole;
indole alkaloid;
tertiary amino compound		antibacterial agent;
antiviral agent;
plant metabolite;
serotonergic antagonist		2012201212.0low000010
methyl gallate
1
gallate esteranti-inflammatory agent;
antioxidant;
plant metabolite		201620168.0low000010
methylergonovine
1
ergoline alkaloid2012201212.0low000010
2,2'-methylenebis(4-methyl-6-tert-butylphenol)
1
diarylmethane2012201212.0low000010
indolebutyric acid
1
indol-3-yl carboxylic acidauxin;
plant hormone;
plant metabolite		2012201212.0low000010
shikimic acid
1
alpha,beta-unsaturated monocarboxylic acid;
cyclohexenecarboxylic acid;
hydroxy monocarboxylic acid		Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite		2012201212.0low000010
catechin
2
catechinantioxidant;
plant metabolite		201520187.5low000020
monocrotaline
1
pyrrolizidine alkaloid2012201212.0low000010
jervine
1
piperidines2012201212.0low000010
glycyrrhetinic acid
1
cyclic terpene ketone;
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		immunomodulator;
plant metabolite		2012201212.0low000010
boldine
1
aporphine alkaloid2012201212.0low000010
indirubin
1
2012201212.0low000010
plumbagin
1
hydroxy-1,4-naphthoquinone;
phenols		anticoagulant;
antineoplastic agent;
immunological adjuvant;
metabolite		2012201212.0low000010
cepharanthine
1
bisbenzylisoquinoline alkaloid;
isoquinolines		2012201212.0low000010
aloe emodin
1
aromatic primary alcohol;
dihydroxyanthraquinone		antineoplastic agent;
plant metabolite		2012201212.0low000010
emetine
1
isoquinoline alkaloid;
pyridoisoquinoline		antiamoebic agent;
anticoronaviral agent;
antiinfective agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
expectorant;
plant metabolite;
protein synthesis inhibitor		201820186.0low000010
osthol
1
botanical anti-fungal agent;
coumarins		metabolite2012201212.0low000010
cytisine
1
alkaloid;
bridged compound;
lactam;
organic heterotricyclic compound;
secondary amino compound		nicotinic acetylcholine receptor agonist;
phytotoxin;
plant metabolite		2012201212.0low000010
bicuculline
1
benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin		2012201212.0low000010
kainic acid
1
dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid		antinematodal drug;
excitatory amino acid agonist		2012201212.0low000010
thymoquinone
1
1,4-benzoquinonesadjuvant;
anti-inflammatory agent;
antidepressant;
antineoplastic agent;
antioxidant;
cardioprotective agent;
plant metabolite		2012201212.0low000010
oleanolic acid
1
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite2012201212.0low000010
podophyllotoxin
1
furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antimitotic;
antineoplastic agent;
keratolytic drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator		2012201212.0low000010
hesperidin
1
3'-hydroxyflavanones;
4'-methoxyflavanones;
dihydroxyflavanone;
disaccharide derivative;
flavanone glycoside;
monomethoxyflavanone;
rutinoside		mutagen2012201212.0low000010
flavone
2
flavonesmetabolite;
nematicide		1996201518.5low001010
azomycin
1
C-nitro compound;
imidazoles		antitubercular agent2012201212.0low000010
eriodictyol
1
flavanones2011201113.0medium000010
3-hydroxyflavone
1
flavonols;
monohydroxyflavone		201520159.0low000010
Berberine chloride (TN)
1
organic molecular entity2012201212.0low000010
vincamine
1
alkaloid ester;
hemiaminal;
methyl ester;
organic heteropentacyclic compound;
vinca alkaloid		antihypertensive agent;
metabolite;
vasodilator agent		2012201212.0low000010
muscarine
1
2012201212.0medium000010
ecdysone
1
14alpha-hydroxy steroid;
22-hydroxy steroid;
25-hydroxy steroid;
2beta-hydroxy steroid;
3beta-sterol;
6-oxo steroid;
ecdysteroid		prohormone2012201212.0low000010
n-deacetyl-n-formylcolchicine
1
cyclic ketone2012201212.0medium000010
camptothecin
1
delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite		2012201212.0low000010
tetradecanoylphorbol acetate
1
acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator		2012201212.0low000010
2-bromoergocryptine mesylate
1
methanesulfonate saltantiparkinson drug2012201212.0medium000010
zingerone
1
methyl ketone;
monomethoxybenzene;
phenols		anti-inflammatory agent;
antiemetic;
antioxidant;
flavouring agent;
fragrance;
plant metabolite;
radiation protective agent		2012201212.0low000010
paclitaxel
1
taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent		2012201212.0low000010
etoposide
1
beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor		2012201212.0low000010
phorbol 12,13-dibutyrate
1
butyrate ester;
phorbol ester;
tertiary alpha-hydroxy ketone		2012201212.0low000010
cephradine
1
beta-lactam antibiotic allergen;
cephalosporin		antibacterial drug2012201212.0low000010
quisqualic acid
1
non-proteinogenic alpha-amino acid2012201212.0low000010
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
2
chromanol;
monocarboxylic acid;
phenols		antioxidant;
ferroptosis inhibitor;
neuroprotective agent;
radical scavenger;
Wnt signalling inhibitor		2011201610.5low000020
colforsin
1
acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist		2012201212.0low000010
swainsonine
1
indolizidine alkaloidantineoplastic agent;
EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor;
immunological adjuvant;
plant metabolite		2012201212.0low000010
castanospermine
1
indolizidine alkaloidanti-HIV-1 agent;
anti-inflammatory agent;
EC 3.2.1.* (glycosidase) inhibitor;
metabolite		2012201212.0low000010
daunorubicin hydrochloride
1
anthracycline2012201212.0low000010
mevastatin
1
2-pyranones;
carboxylic ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		antifungal agent;
apoptosis inducer;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
fungal metabolite;
Penicillium metabolite		2012201212.0low000010
ursolic acid
1
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		geroprotector;
plant metabolite		2012201212.0low000010
norharman
1
beta-carbolines;
mancude organic heterotricyclic parent		fungal metabolite;
marine metabolite		2012201212.0low000010
betulinic acid
1
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		anti-HIV agent;
anti-inflammatory agent;
antimalarial;
antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
plant metabolite		2012201212.0low000010
baicalin
1
dihydroxyflavone;
glucosiduronic acid;
glycosyloxyflavone;
monosaccharide derivative		antiatherosclerotic agent;
antibacterial agent;
anticoronaviral agent;
antineoplastic agent;
antioxidant;
cardioprotective agent;
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
ferroptosis inhibitor;
neuroprotective agent;
non-steroidal anti-inflammatory drug;
plant metabolite;
prodrug		201520159.0low000010
epigallocatechin gallate
2
flavans;
gallate ester;
polyphenol		antineoplastic agent;
antioxidant;
apoptosis inducer;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent;
plant metabolite		2012201510.5low000020
baccatin iii
1
acetate ester;
benzoate ester;
tetracyclic diterpenoid		plant metabolite2012201212.0low000010
taleranol
1
macrolide2012201212.0low000010
narasin
1
diterpene glycoside2012201212.0high000010
quassin
1
triterpenoid2012201212.0low000010
tomatidine
1
3beta-hydroxy steroid;
azaspiro compound;
oxaspiro compound		2012201212.0low000010
aloxistatin
1
epoxide;
ethyl ester;
L-leucine derivative;
monocarboxylic acid amide		anticoronaviral agent;
cathepsin B inhibitor		2012201212.0low000010
rutecarpine
1
beta-carbolines2012201212.0low000010
bergenin
1
trihydroxybenzoic acidmetabolite2012201212.0low000010
pinocembrin
3
(2S)-flavan-4-one;
dihydroxyflavanone		antineoplastic agent;
antioxidant;
metabolite;
neuroprotective agent;
vasodilator agent		2010201511.7low000120
tangeretin
1
pentamethoxyflavoneantineoplastic agent;
plant metabolite		1996199628.0low001000
artemisinin
1
organic peroxide;
sesquiterpene lactone		antimalarial;
plant metabolite		201820186.0low000010
isoscopoletin
1
aromatic ether;
hydroxycoumarin		plant metabolite2012201212.0low000010
vinburnine
1
alkaloid2012201212.0low000010
epicatechin
2
catechin;
polyphenol		antioxidant2012201510.5low000020
hesperetin
4
3'-hydroxyflavanones;
4'-methoxyflavanones;
monomethoxyflavanone;
trihydroxyflavanone		antineoplastic agent;
antioxidant;
plant metabolite		1996201515.8low001120
magnolol
1
biphenyls2012201212.0low000010
honokiol
1
biphenyls2012201212.0low000010
chelerythrine chloride
1
2012201212.0low000010
betulin
1
diol;
pentacyclic triterpenoid		analgesic;
anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
metabolite		2012201212.0low000010
tetrahydroalstonine
1
methyl ester;
organic heteropentacyclic compound;
yohimban alkaloid		plant metabolite2012201212.0high000010
hernandezine
1
bisbenzylisoquinoline alkaloid;
isoquinolines		2012201212.0low000010
picropodophyllin
1
furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antineoplastic agent;
insulin-like growth factor receptor 1 antagonist;
plant metabolite;
tyrosine kinase inhibitor		2012201212.0low000010
kaurenoic acid
1
ent-kaurane diterpenoidanti-HIV-1 agent;
antineoplastic agent;
plant metabolite		201820186.0low000010
tetrandrine
1
bisbenzylisoquinoline alkaloid;
isoquinolines		2012201212.0low000010
dehydrocostus lactone
1
gamma-lactone;
guaiane sesquiterpenoid;
organic heterotricyclic compound;
sesquiterpene lactone		antimycobacterial drug;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 2 inhibitor;
metabolite;
trypanocidal drug		2012201212.0low000010
madecassic acid
1
monocarboxylic acid;
pentacyclic triterpenoid;
tetrol		antioxidant;
plant metabolite		2012201212.0low000010
panaxadiol
1
triterpenoid saponin2012201212.0low000010
tryptanthrine
1
alkaloid antibiotic;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		2012201212.0low000010
homoeriodictyol
4
3'-methoxyflavanones;
4'-hydroxyflavanones;
monomethoxyflavanone;
trihydroxyflavanone		flavouring agent;
metabolite		1996201515.8medium001120
umuhengerin
1
1996199628.0medium001000
4-hydroxyindole
1
hydroxyindoles;
phenols		2012201212.0low000010
4'-methoxyflavone
1
ether;
flavonoids		1996199628.0low001000
eriocitrin
1
3'-hydroxyflavanones;
4'-hydroxyflavanones;
disaccharide derivative;
flavanone glycoside;
rutinoside;
trihydroxyflavanone		antioxidant2012201212.0low000010
7,8-dihydromethysticin
1
2-pyranones;
aromatic ether		2012201212.0low000010
nicotine
1
3-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic		2012201212.0low000010
cinchonine
1
(8xi)-cinchonan-9-ol;
cinchona alkaloid		metabolite2012201212.0low000010
aucubin
1
organic molecular entitymetabolite2012201212.0low000010
lupinine
1
quinolizidine alkaloid2012201212.0low000010
matrine
1
alkaloid2012201212.0low000010
friedelin
1
cyclic terpene ketone;
pentacyclic triterpenoid		anti-inflammatory drug;
antipyretic;
non-narcotic analgesic;
plant metabolite		2012201212.0low000010
catalpol
1
organic molecular entitymetabolite2012201212.0low000010
quinine hydrochloride
1
2012201212.0high000010
sarsasapogenin
1
sapogenin2012201212.0low000010
corynanthine
1
yohimban alkaloid2012201212.0low000010
prunin protein, prunus
1
(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
flavanone 7-O-beta-D-glucoside;
monosaccharide derivative		antibacterial agent;
antilipemic drug;
hypoglycemic agent;
metabolite		2012201212.0low000010
podocarpic acid
1
abietane diterpenoid2012201212.0low000010
harmol hydrochloride
1
2012201212.0medium000010
5-Methoxyflavone
1
ether;
flavonoids		2012201212.0medium000010
eupatorin
1
dihydroxyflavone;
polyphenol;
trimethoxyflavone		anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
Brassica napus metabolite;
calcium channel blocker;
P450 inhibitor;
vasodilator agent		1996199628.0low001000
10-hydroxycamptothecin
1
pyranoindolizinoquinoline2012201212.0low000010
3,5,7,3',4'-pentamethoxyflavone
1
2012201212.0low000010
karanjin
1
extended flavonoid1996199628.0low001000
corydaline
1
isoquinoline alkaloid;
isoquinolines		2012201212.0low000010
demissidine
1
alkaloid;
organic heteropolycyclic compound;
steroid		2012201212.0medium000010
cinchonidine
1
(8xi)-cinchonan-9-ol;
cinchona alkaloid		metabolite2012201212.0low000010
propidium iodide
1
organic iodide salt2012201212.0low000010
tryptoline
1
beta-carbolines2012201212.0low000010
deguelin
1
aromatic ether;
diether;
organic heteropentacyclic compound;
rotenones		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
mitochondrial NADH:ubiquinone reductase inhibitor;
plant metabolite		2012201212.0low000010
catechin
1
hydrategeroprotector2012201212.0medium000010
daidzin
2
7-hydroxyisoflavones 7-O-beta-D-glucoside;
hydroxyisoflavone;
monosaccharide derivative		plant metabolite1996201220.0low001010
cafestol
1
diterpenoid;
furans;
organic heteropentacyclic compound;
primary alcohol;
tertiary alcohol		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
hypoglycemic agent;
plant metabolite		2012201212.0low000010
parthenolide
2
germacranolide2012201411.0low000020
homoorientin
1
flavone C-glycoside;
tetrahydroxyflavone		antineoplastic agent;
radical scavenger		2012201212.0low000010
liquiritigenin
1
4',7-dihydroxyflavanonehormone agonist;
plant metabolite		201720177.0low000010
asiatic acid
1
monocarboxylic acid;
pentacyclic triterpenoid;
triol		angiogenesis modulating agent;
metabolite		2012201212.0low000010
angustmycin a
1
6-aminopurines2012201212.0low000010
razadyne
1
2012201212.0low000010
phytosphingosine
1
amino alcohol;
sphingoid;
triol		mouse metabolite;
Saccharomyces cerevisiae metabolite		2012201212.0low000010
tetradecanoylphorbol acetate
1
2012201212.0low000010
celastrol
1
monocarboxylic acid;
pentacyclic triterpenoid		anti-inflammatory drug;
antineoplastic agent;
antioxidant;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Hsp90 inhibitor;
metabolite		2012201212.0low000010
4'-demethylepipodophyllotoxin
1
furonaphthodioxole;
organic heterotetracyclic compound;
phenols		antineoplastic agent2012201212.0low000010
aromadedrin
2
4'-hydroxyflavanones;
dihydroflavonols;
secondary alpha-hydroxy ketone;
tetrahydroxyflavanone		metabolite2011201710.0low000020
n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine
1
leucine derivative2012201212.0low000010
e 64
1
dicarboxylic acid monoamide;
epoxy monocarboxylic acid;
guanidines;
L-leucine derivative;
zwitterion		antimalarial;
antiparasitic agent;
protease inhibitor		2012201212.0low000010
sinensetin
3
pentamethoxyflavoneplant metabolite1996201516.3low001020
harmalol hydrochloride
1
2012201212.0medium000010
hyoscyamine
1
tropane alkaloid2012201212.0low000010
schizandrin a
1
2012201212.0low000010
schizandrin b
1
aromatic ether;
cyclic acetal;
organic heterotetracyclic compound;
oxacycle;
tannin		anti-asthmatic agent;
anti-inflammatory agent;
antilipemic drug;
antioxidant;
apoptosis inhibitor;
hepatoprotective agent;
nephroprotective agent;
neuroprotective agent;
plant metabolite		2012201212.0medium000010
cryptotanshinone
1
abietane diterpenoidanticoronaviral agent2012201212.0low000010
isosakuranetin
3
(2S)-flavan-4-one;
4'-methoxyflavanones;
dihydroxyflavanone;
monomethoxyflavanone		plant metabolite1996201218.0medium001110
isovitexin
1
C-glycosyl compound;
trihydroxyflavone		EC 3.2.1.20 (alpha-glucosidase) inhibitor;
metabolite		2012201212.0low000010
sclareol
1
labdane diterpenoidantifungal agent;
antimicrobial agent;
apoptosis inducer;
fragrance;
plant metabolite		2012201212.0low000010
tanshinone ii a
1
abietane diterpenoid2012201212.0low000010
leucodin
1
sesquiterpene lactone2012201212.0low000010
limonin
1
epoxide;
furans;
hexacyclic triterpenoid;
lactone;
limonoid;
organic heterohexacyclic compound		inhibitor;
metabolite;
volatile oil component		2012201212.0low000010
maduramicin
1
2012201212.0low000010
chelidonine
1
alkaloid antibiotic;
alkaloid fundamental parent;
benzophenanthridine alkaloid		2012201212.0low000010
troleandomycin
1
acetate ester;
epoxide;
macrolide antibiotic;
monosaccharide derivative;
polyketide;
semisynthetic derivative		EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitor;
xenobiotic		2012201212.0low000010
santonin
1
botanical anti-fungal agent;
santonin		plant metabolite2012201212.0low000010
sitosterol, (3beta)-isomer
1
3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
C29-steroid;
phytosterols;
stigmastane sterol		anticholesteremic drug;
antioxidant;
mouse metabolite;
plant metabolite;
sterol methyltransferase inhibitor		2012201212.0low000010
vincristine sulfate
1
organic sulfate saltantineoplastic agent;
geroprotector		2012201212.0low000010
anisomycin
1
monohydroxypyrrolidine;
organonitrogen heterocyclic antibiotic		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
antiparasitic agent;
bacterial metabolite;
DNA synthesis inhibitor;
protein synthesis inhibitor		2012201212.0low000010
acetylstrophanthidin
1
acetate esteranti-arrhythmia drug2012201212.0low000010
gardenin a
1
201520159.0low000010
Harringtonine
1
alkaloid2012201212.0low000010
acivicin
1
isoxazoles;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		antileishmanial agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor;
glutamine antagonist;
metabolite		2012201212.0low000010
ketopinic acid
1
2012201212.0medium000010
wortmannin
1
acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent		2012201212.0low000010
gitoxigenin
1
14beta-hydroxy steroid;
16beta-hydroxy steroid;
3beta-hydroxy steroid		2012201212.0low000010
graveoline
1
quinolines2012201212.0low000010
4-oxy-6-(4-oxybezoyloxy)dauc-8,9-en
1
2012201212.0low000010
naringenin
5
(2S)-flavan-4-one;
naringenin		expectorant;
plant metabolite		1996201714.0low001130
ouabain
1
11alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite		2012201212.0low000010
puromycin
1
puromycinsantiinfective agent;
antimicrobial agent;
antineoplastic agent;
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor;
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor;
nucleoside antibiotic;
protein synthesis inhibitor		2012201212.0low000010
taxifolin
5
taxifolinmetabolite1996201515.8low001130
mimosine
1
4-pyridones;
amino acid zwitterion;
non-proteinogenic L-alpha-amino acid		EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite		2012201212.0low000010
eriodictyol
5
3'-hydroxyflavanones;
tetrahydroxyflavanone		2008201711.6low000230
arbutin
1
beta-D-glucoside;
monosaccharide derivative		Escherichia coli metabolite;
plant metabolite		2012201212.0low000010
quinidine
1
cinchona alkaloidalpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker		2012201212.0low000010
conessine
1
steroid alkaloid;
tertiary amino compound		antibacterial agent;
antimalarial;
H3-receptor antagonist;
plant metabolite		2012201212.0low000010
griseofulvin
1
1-benzofurans;
antibiotic antifungal drug;
benzofuran antifungal drug;
organochlorine compound;
oxaspiro compound		antibacterial agent;
Penicillium metabolite		2012201212.0low000010
digitoxin
1
cardenolide glycosideEC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor2012201212.0low000010
hyperforin
1
2012201212.0low000010
deltaline
1
acetate ester;
cyclic acetal;
diterpene alkaloid;
organic polycyclic compound;
tertiary alcohol;
tertiary amino compound		2012201212.0high000010
ingenol
1
cyclic terpene ketone;
tetracyclic diterpenoid		2012201212.0low000010
glaucolide b
1
carboxylic ester;
ketone		201820186.0medium000010
picrotin
1
diol;
epoxide;
gamma-lactone;
organic heteropentacyclic compound;
picrotoxane sesquiterpenoid;
tertiary alcohol		plant metabolite2012201212.0low000010
picrotoxinin
1
epoxide;
gamma-lactone;
organic heteropentacyclic compound;
picrotoxane sesquiterpenoid;
tertiary alcohol		GABA antagonist;
plant metabolite;
serotonergic antagonist		2012201212.0low000010
naringin
1
(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
disaccharide derivative;
neohesperidoside		anti-inflammatory agent;
antineoplastic agent;
metabolite		2012201212.0low000010
isonaringin
2
(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
disaccharide derivative;
rutinoside		anti-inflammatory agent;
antioxidant;
metabolite		1996201220.0low001010
ochratoxin a
1
isochromanes;
monocarboxylic acid amide;
N-acyl-L-phenylalanine;
organochlorine compound;
phenylalanine derivative		Aspergillus metabolite;
calcium channel blocker;
carcinogenic agent;
mycotoxin;
nephrotoxin;
Penicillium metabolite;
teratogenic agent		2012201212.0low000010
gingerol
1
beta-hydroxy ketone;
guaiacols		antineoplastic agent;
plant metabolite		2012201212.0low000010
securinine
1
indolizines2012201212.0low000010
Dubinidine
1
organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle		2012201212.0low000010
cyclopamine
1
piperidinesglioma-associated oncogene inhibitor2012201212.0low000010
doxorubicin hydrochloride
1
anthracycline2012201212.0low000010
vinpocetine
1
alkaloidgeroprotector2012201212.0low000010
dihydroergocristine monomesylate
1
methanesulfonate saltalpha-adrenergic antagonist;
geroprotector;
vasodilator agent		2012201212.0low000010
e-z cinnamic acid
1
cinnamic acidplant metabolite201820186.0low000010
tretinoin
1
retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule		2012201212.0low000010
resveratrol
2
resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger		2012201510.5low000020
ferulic acid
2
ferulic acidsanti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
MALDI matrix material;
plant metabolite		201220189.0low000020
thapsigargin
1
butyrate ester;
organic heterotricyclic compound;
sesquiterpene lactone		calcium channel blocker;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor		2012201212.0low000010
mycophenolic acid
1
2-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic		2012201212.0low000010
alitretinoin
1
retinoic acidantineoplastic agent;
keratolytic drug;
metabolite;
retinoid X receptor agonist		2012201212.0low000010
L-cycloserine
1
4-amino-1,2-oxazolidin-3-oneanti-HIV agent;
anticonvulsant;
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor		2012201212.0low000010
12-deoxyphorbol 13-acetate
1
phorbol estermetabolite2012201212.0low000010
dactinomycin
1
actinomycinmutagen2012201212.0low000010
aphidicolin
1
tetracyclic diterpenoidantimicrobial agent;
antimitotic;
antineoplastic agent;
antiviral drug;
apoptosis inducer;
Aspergillus metabolite;
DNA synthesis inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
fungal metabolite		2012201212.0low000010
(+)-usnic acid
1
usnic acid2012201212.0low000010
beta, beta-dimethylacrylshikonin, (+)-isomer
1
hydroxy-1,4-naphthoquinone2012201212.0medium000010
shikonin
1
hydroxy-1,4-naphthoquinone2012201212.0low000010
rhapontin
1
rhaponticinangiogenesis inhibitor;
anti-allergic agent;
anti-inflammatory agent;
antilipemic drug;
antineoplastic agent;
apoptosis inducer;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
hypoglycemic agent;
neuroprotective agent;
plant metabolite		2012201212.0low000010
2-hydroxycinnamic acid
1
2-coumaric acid;
phenols		antioxidant;
metabolite		201820186.0low000010
piperine
1
benzodioxoles;
N-acylpiperidine;
piperidine alkaloid;
tertiary carboxamide		food component;
human blood serum metabolite;
NF-kappaB inhibitor;
plant metabolite		2012201212.0low000010
rauwolscine
1
methyl 17-hydroxy-20xi-yohimban-16-carboxylate2012201212.0low000010
amygdalin
1
amygdalinantineoplastic agent;
apoptosis inducer;
plant metabolite		2012201212.0low000010
hydrastine, (r-(r*,s*))-isomer
1
isoquinolines2012201212.0low000010
vasicine
1
2012201212.0low000010
3,3',4,5'-tetrahydroxystilbene
1
catechols;
polyphenol;
resorcinols;
stilbenol		antineoplastic agent;
apoptosis inducer;
geroprotector;
hypoglycemic agent;
plant metabolite;
protein kinase inhibitor;
tyrosine kinase inhibitor		2012201212.0low000010
caffeic acid
2
caffeic acidgeroprotector;
mouse metabolite		201220189.0low000020
cotinine
1
N-alkylpyrrolidine;
pyridines;
pyrrolidin-2-ones;
pyrrolidine alkaloid		antidepressant;
biomarker;
human xenobiotic metabolite;
plant metabolite		2012201212.0low000010
heliotrine
1
pyrrolizines2012201212.0low000010
sclareolide
1
naphthofuran2012201212.0low000010
hypocrellin b
1
2012201212.0low000010
capsaicin
1
capsaicinoidnon-narcotic analgesic;
TRPV1 agonist;
voltage-gated sodium channel blocker		2012201212.0low000010
aurapten
1
coumarins;
monoterpenoid		antihypertensive agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
dopaminergic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
gamma-secretase modulator;
gastrointestinal drug;
hepatoprotective agent;
matrix metalloproteinase inhibitor;
neuroprotective agent;
plant metabolite;
PPARalpha agonist;
vulnerary		2012201212.0low000010
chlorogenic acid
1
cinnamate ester;
tannin		food component;
plant metabolite		2012201212.0low000010
3-methoxy-N-(4-methyl-2-thiazolyl)benzamide
1
benzamides2007200717.0medium000100
fumonisin b2
1
diester;
diol;
fumonisin;
primary amino compound		Aspergillus metabolite;
carcinogenic agent		2012201212.0low000010
scopolamine
1
3-hydroxy carboxylic acid201820186.0high000010
lincomycin
1
carbohydrate-containing antibiotic;
L-proline derivative;
monocarboxylic acid amide;
pyrrolidinecarboxamide;
S-glycosyl compound		antimicrobial agent;
bacterial metabolite		2012201212.0low000010
valinomycin
1
cyclodepsipeptide;
macrocycle		antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore		2012201212.0low000010
orlistat
1
beta-lactone;
carboxylic ester;
formamides;
L-leucine derivative		anti-obesity agent;
bacterial metabolite;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor		2012201212.0low000010
12-deoxyphorbolphenylacetate-20-acetate
1
2012201212.0low000010
brassinin
1
dithiocarbamic ester;
indole phytoalexin		2012201212.0low000010
chaetomellic acid a
1
2012201212.0low000010
hirsutine
1
2012201212.0low000010
3-deoxyvasicine, hydrochloride
1
2012201212.0medium000010
emetine dihydrochloride
1
hydrochlorideanticoronaviral agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
protein synthesis inhibitor		2012201212.0low000010
salinomycin
1
polyketide;
spiroketal		animal growth promotant;
potassium ionophore		2012201212.0low000010
silybin
2
1996201220.0low001010
5,6-dehydrokawain
1
2-pyranones;
aromatic ether		2012201212.0low000010
9,10-dihydrolysergol
1
2012201212.0low000010
geranylgeranic acid
1
alpha,beta-unsaturated monocarboxylic acid;
diterpenoid;
methyl-branched fatty acid;
trienoic fatty acid		2012201212.0low000010
quercetin
16
7-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger		1996201812.1low0014110
dinoprostone
1
prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic		2012201212.0low000010
dinoprost
1
monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite		2012201212.0low000010
biochanin a
1
4'-methoxyisoflavones;
7-hydroxyisoflavones		antineoplastic agent;
EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor		2012201212.0low000010
formononetin
1
4'-methoxyisoflavones;
7-hydroxyisoflavones		phytoestrogen;
plant metabolite		2012201212.0low000010
prostaglandin b1
1
prostaglandins Bhuman metabolite2012201212.0low000010
sterigmatocystin
1
sterigmatocystinsmetabolite2012201212.0low000010
3,7-dimethoxy-5,3',4'-trihydroxyflavone
3
dimethoxyflavone;
trihydroxyflavone		EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor;
metabolite		2012201410.7high000030
vitexin
1
C-glycosyl compound;
trihydroxyflavone		antineoplastic agent;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
plant metabolite;
platelet aggregation inhibitor		2012201212.0low000010
acacetin
5
dihydroxyflavone;
monomethoxyflavone		anticonvulsant;
plant metabolite		1996201714.2low001130
apigenin
7
trihydroxyflavoneantineoplastic agent;
metabolite		1996201712.7low001150
luteolin
8
3'-hydroxyflavonoid;
tetrahydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
c-Jun N-terminal kinase inhibitor;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
immunomodulator;
nephroprotective agent;
plant metabolite;
radical scavenger;
vascular endothelial growth factor receptor antagonist		1996201712.1low001160
quercitrin
1
alpha-L-rhamnoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		antileishmanial agent;
antioxidant;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite		2012201212.0low000010
scopoletin
1
hydroxycoumarinplant growth regulator;
plant metabolite		2012201212.0low000010
hymecromone
1
hydroxycoumarinantineoplastic agent;
hyaluronic acid synthesis inhibitor		2012201212.0low000010
5'-o-caffeoylquinic acid
1
cinnamate ester;
cyclitol carboxylic acid		plant metabolite201820186.0medium000010
gossypetin
3
7-hydroxyflavonol;
hexahydroxyflavone		plant metabolite2011201510.7low000030
chrysoeriol
4
monomethoxyflavone;
trihydroxyflavone		antineoplastic agent;
antioxidant;
metabolite		1996201515.2low001120
quercetin 3-o-methyl ether
5
monomethoxyflavone;
tetrahydroxyflavone		antimicrobial agent;
metabolite		2009201611.0medium000140
ayanin
3
dihydroxyflavone;
trimethoxyflavone		plant metabolite2012201410.7medium000030
apigetrin
1
beta-D-glucoside;
dihydroxyflavone;
glycosyloxyflavone;
monosaccharide derivative		antibacterial agent;
metabolite;
non-steroidal anti-inflammatory drug		201820186.0low000010
alprostadil
1
prostaglandins Eanticoagulant;
human metabolite;
platelet aggregation inhibitor;
vasodilator agent		2012201212.0low000010
apiin
1
beta-D-glucoside;
dihydroxyflavone;
glycosyloxyflavone		EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
plant metabolite		201520159.0low000010
quercetin 3-o-glucopyranoside
4
beta-D-glucoside;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antineoplastic agent;
antioxidant;
antipruritic drug;
bone density conservation agent;
geroprotector;
histamine antagonist;
osteogenesis regulator;
plant metabolite		201220169.8low000040
rutin
4
disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone		antioxidant;
metabolite		1996201814.8low001030
kaempferol
9
7-hydroxyflavonol;
flavonols;
tetrahydroxyflavone		antibacterial agent;
geroprotector;
human blood serum metabolite;
human urinary metabolite;
human xenobiotic metabolite;
plant metabolite		1996201812.0low001170
senecionine
1
lactone;
pyrrolizidine alkaloid;
tertiary alcohol		plant metabolite2012201212.0low000010
genistein
1
7-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor		2012201212.0low000010
amphotericin b
1
antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic		antiamoebic agent;
antiprotozoal drug;
bacterial metabolite		2012201212.0low000010
butein
1
chalcones;
polyphenol		antineoplastic agent;
antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
geroprotector;
hypoglycemic agent;
plant metabolite;
radiosensitizing agent;
tyrosine kinase inhibitor		2012201212.0low000010
sulfuretin
1
1-benzofurans2012201212.0low000010
genistin
1
7-hydroxyisoflavones 7-O-beta-D-glucoside2012201212.0low000010
chartreusin
1
benzochromenone;
glycoside		2012201212.0low000010
7-hydroxycoumarin
1
hydroxycoumarinfluorescent probe;
food component;
plant metabolite		201820186.0low000010
budlein a
1
sesquiterpenoid201820186.0medium000010
methysticin
1
2-pyranones;
aromatic ether		2012201212.0high000010
yangonin
1
2-pyranones;
aromatic ether		2012201212.0low000010
zearalenone
1
macrolide;
resorcinols		fungal metabolite;
mycoestrogen		2012201212.0low000010
amentoflavone
1
biflavonoid;
hydroxyflavone;
ring assembly		angiogenesis inhibitor;
antiviral agent;
cathepsin B inhibitor;
P450 inhibitor;
plant metabolite		1996199628.0low001000
azaleatin
3
7-hydroxyflavonol;
monomethoxyflavone;
tetrahydroxyflavone		plant metabolite2009201611.7high000120
baicalein
3
trihydroxyflavoneangiogenesis inhibitor;
anti-inflammatory agent;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 4.1.1.17 (ornithine decarboxylase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hormone antagonist;
plant metabolite;
prostaglandin antagonist;
radical scavenger		1996201516.3low001020
chrysin
3
7-hydroxyflavonol;
dihydroxyflavone		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
EC 2.7.11.18 (myosin-light-chain kinase) inhibitor;
hepatoprotective agent;
plant metabolite		1996201218.0low001110
datiscetin
3
7-hydroxyflavonol;
tetrahydroxyflavone		1996201516.3high001020
diosmetin
7
3'-hydroxyflavonoid;
monomethoxyflavone;
trihydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
bone density conservation agent;
cardioprotective agent;
plant metabolite;
tropomyosin-related kinase B receptor agonist;
vasodilator agent		1996201712.7low001150
diosmin
2
dihydroxyflavanone;
disaccharide derivative;
glycosyloxyflavone;
monomethoxyflavone;
rutinoside		anti-inflammatory agent;
antioxidant		2012201510.5low000020
fisetin
4
3'-hydroxyflavonoid;
7-hydroxyflavonol;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
metabolite;
plant metabolite		1996201514.5low001030
galangin
7
7-hydroxyflavonol;
trihydroxyflavone		antimicrobial agent;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
plant metabolite		1996201812.6low001150
gossypin
2
7-hydroxyflavonol;
glycosyloxyflavone;
monosaccharide derivative;
pentahydroxyflavone		neuroprotective agent;
plant metabolite		2011201511.0low000020
hinokiflavone
1
aromatic ether;
biflavonoid;
hydroxyflavone		antineoplastic agent;
metabolite;
neuroprotective agent		1996199628.0low001000
hyperoside
1
beta-D-galactoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		hepatoprotective agent;
plant metabolite		201620168.0low000010
3-methylquercetin
12
7-hydroxyflavonol;
monomethoxyflavone;
tetrahydroxyflavone		anticoagulant;
EC 1.14.18.1 (tyrosinase) inhibitor;
metabolite		1996201612.9low001380
kaempferide
5
7-hydroxyflavonol;
monomethoxyflavone;
trihydroxyflavone		antihypertensive agent;
metabolite		1996201514.8low001130
morin
3
7-hydroxyflavonol;
pentahydroxyflavone		angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent		1996201516.3low001020
myricetin
6
7-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite		1996201811.8low001050
myricitrin
1
alpha-L-rhamnoside;
glycosyloxyflavone;
monosaccharide derivative;
pentahydroxyflavone		anti-allergic agent;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
plant metabolite		201520159.0low000010
patuletin
1
flavonols;
monomethoxyflavone;
pentahydroxyflavone		analgesic;
antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
lipoxygenase inhibitor;
metabolite		2011201113.0low000010
quercetagetin
4
flavonols;
hexahydroxyflavone		antioxidant;
antiviral agent;
plant metabolite		1996201515.0low001030
rhamnetin
5
monomethoxyflavone;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
metabolite		1996201415.4low001130
robinetin
3
7-hydroxyflavonol;
pentahydroxyflavone		plant metabolite1996201715.7medium001020
santin
1
dihydroxyflavone;
trimethoxyflavone		plant metabolite201820186.0low000010
sciadopitysin
1
biflavonoid;
hydroxyflavone;
methoxyflavone;
ring assembly		bone density conservation agent;
platelet aggregation inhibitor		1996199628.0low001000
scutellarein
1
tetrahydroxyflavonemetabolite201520159.0low000010
tricetin
1
pentahydroxyflavoneantineoplastic agent;
metabolite		201520159.0low000010
tricin
1
3'-methoxyflavones;
dimethoxyflavone;
trihydroxyflavone		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
metabolite		201720177.0low000010
wogonin
1
dihydroxyflavone;
monomethoxyflavone		angiogenesis inhibitor;
antineoplastic agent;
cyclooxygenase 2 inhibitor;
plant metabolite		2012201212.0low000010
coumestrol
1
coumestans;
delta-lactone;
polyphenol		anti-inflammatory agent;
antioxidant;
plant metabolite		2012201212.0low000010
daidzein
2
7-hydroxyisoflavonesantineoplastic agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
phytoestrogen;
plant metabolite		1996201220.0low001010
3,4-di-o-caffeoylquinic acid
1
quinic acid201820186.0low000010
caffeic acid phenethyl ester
1
alkyl caffeate esteranti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiviral agent;
immunomodulator;
metabolite;
neuroprotective agent		2012201212.0low000010
rosmarinic acid
1
rosmarinic acidgeroprotector;
plant metabolite		2012201212.0low000010
psi-baptigenin
1
7-hydroxyisoflavones;
benzodioxoles		antiprotozoal drug;
plant metabolite		1996199628.0low001000
wedelolactone
1
aromatic ether;
coumestans;
delta-lactone;
polyphenol		antineoplastic agent;
apoptosis inducer;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
hepatoprotective agent;
metabolite		2012201212.0low000010
rottlerin
1
aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite		2012201212.0low000010
ellagic acid
2
catechols;
cyclic ketone;
lactone;
organic heterotetracyclic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor;
EC 2.4.1.1 (glycogen phosphorylase) inhibitor;
EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor;
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor;
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
food additive;
fungal metabolite;
geroprotector;
plant metabolite;
skin lightening agent		2011201212.5low000020
7-hydroxyflavone
1
hydroxyflavonoid2012201212.0low000010
prostaglandin a1
1
prostaglandins A2012201212.0low000010
syringetin
1
3',5'-dimethoxyflavone;
3'-methoxyflavones;
7-hydroxyflavonol;
dimethoxyflavone;
tetrahydroxyflavone		metabolite;
platelet aggregation inhibitor		1996199628.0low001000
tectochrysin
1
monohydroxyflavone;
monomethoxyflavone		antidiarrhoeal drug;
antineoplastic agent;
plant metabolite		1996199628.0low001000
cerulenin
1
epoxide;
monocarboxylic acid amide		antifungal agent;
antiinfective agent;
antilipemic drug;
antimetabolite;
antimicrobial agent;
fatty acid synthesis inhibitor		2012201212.0low000010
4',7-dihydroxyflavone
1
dihydroxyflavonemetabolite201720177.0low000010
astragalin
1
beta-D-glucoside;
kaempferol O-glucoside;
monosaccharide derivative;
trihydroxyflavone		plant metabolite;
trypanocidal drug		1996199628.0low001000
rhoifolin
1
dihydroxyflavone;
glycosyloxyflavone;
neohesperidoside		metabolite2012201212.0low000010
vitexin rhamnoside
1
C-glycosyl compound;
disaccharide derivative;
trihydroxyflavone		plant metabolite2012201212.0medium000010
domoic acid
1
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid;
tricarboxylic acid		algal metabolite;
hapten;
marine metabolite;
neuromuscular agent;
neurotoxin		2012201212.0low000010
isotretinoin
1
retinoic acidantineoplastic agent;
keratolytic drug;
teratogenic agent		2012201212.0low000010
cyclosporine
1
homodetic cyclic peptideanti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite		2012201212.0low000010
natamycin
1
antibiotic antifungal drug;
dicarboxylic acid monoester;
epoxide;
macrolide antibiotic;
monosaccharide derivative;
polyene antibiotic		antifungal agrochemical;
antimicrobial food preservative;
apoptosis inducer;
bacterial metabolite;
ophthalmology drug		2012201212.0low000010
sirolimus
1
antibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol		antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor		2012201212.0low000010
brefeldin a
1
macrolide antibioticPenicillium metabolite2012201212.0low000010
cytochalasin b
1
cytochalasin;
lactam;
lactone;
organic heterotricyclic compound		actin polymerisation inhibitor;
metabolite;
mycotoxin;
platelet aggregation inhibitor		2012201212.0low000010
vinorelbine
1
acetate ester;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
ring assembly;
vinca alkaloid		antineoplastic agent;
photosensitizing agent		2012201212.0low000010
bisdemethoxycurcumin
1
beta-diketone;
diarylheptanoid;
enone;
polyphenol		EC 3.2.1.1 (alpha-amylase) inhibitor;
metabolite		2012201212.0low000010
3,3'-di-o-methylquercetin
1
3'-methoxyflavones;
dimethoxyflavone;
trihydroxyflavone		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
plant metabolite		1996199628.0medium001000
fustin
1
1996199628.0low001000
andrographolide
1
carbobicyclic compound;
gamma-lactone;
labdane diterpenoid;
primary alcohol;
secondary alcohol		anti-HIV agent;
anti-inflammatory drug;
antineoplastic agent;
metabolite		2012201212.0low000010
isorhamnetin-3-o-galactoside
1
beta-D-galactoside;
glycosyloxyflavone;
monomethoxyflavone;
monosaccharide derivative;
trihydroxyflavone		metabolite201620168.0high000010
isorhamnetin 3-o-glucoside
3
beta-D-glucoside;
glycosyloxyflavone;
monomethoxyflavone;
monosaccharide derivative;
trihydroxyflavone		metabolite1996201616.0low001020
ombuine
3
dimethoxyflavone;
flavonols;
trihydroxyflavone		anti-inflammatory agent;
plant metabolite		2012201410.7high000030
tiliroside
1
cinnamate ester;
glycosyloxyflavone;
monosaccharide derivative;
trihydroxyflavone		plant metabolite1996199628.0low001000
spiraeoside
2
beta-D-glucoside;
flavonols;
monosaccharide derivative;
quercetin O-glucoside;
tetrahydroxyflavone		antineoplastic agent;
antioxidant;
plant metabolite		201520187.5low000020
3',4',7-trihydroxyflavone
1
flavones201720177.0low000010
5-hydroxy-3,3',4',7-tetramethoxyflavone
2
3'-methoxyflavones;
monohydroxyflavone;
tetramethoxyflavone		plant metabolite2012201411.0low000020
6,7-dihydroxyflavone
1
2012201212.0low000010
flavokawain a
1
chalcones2012201212.0low000010
flavokawain b
1
chalcones;
dimethoxybenzene;
phenols		anti-inflammatory agent;
antileishmanial agent;
antineoplastic agent;
apoptosis inducer;
metabolite		2012201212.0low000010
furanoheliangolide
1
201820186.0low000010
kavain
1
racemateglycine receptor antagonist2012201212.0low000010
abscisic acid, (+,-)-isomer
1
abscisic acidsabscisic acid receptor agonist2012201212.0medium000010
3',4',5'-O-trimethyltricetin
1
3',5'-dimethoxyflavone;
dihydroxyflavone;
trimethoxyflavone		1996199628.0medium001000
veratrine
1
alkaloid2012201212.0low000010
vinblastine sulfate
1
2012201212.0low000010
catharanthine
1
alkaloid ester;
bridged compound;
methyl ester;
monoterpenoid indole alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		2012201212.0low000010
cytochalasin e
1
cytochalasan alkaloidmetabolite2012201212.0low000010
cytochalasin d
1
2012201212.0medium000010
sinomenine
1
morphinane alkaloid2012201212.0low000010
ecdysterone
1
14alpha-hydroxy steroid;
20-hydroxy steroid;
22-hydroxy steroid;
25-hydroxy steroid;
2beta-hydroxy steroid;
3beta-sterol;
ecdysteroid;
phytoecdysteroid		animal metabolite;
plant metabolite		2012201212.0low000010
bleomycin
1
bleomycinantineoplastic agent;
metabolite		2012201212.0low000010
bakuchiol
1
2012201212.0low000010
zerumbone
1
cyclic ketone;
sesquiterpenoid		anti-inflammatory agent;
glioma-associated oncogene inhibitor;
plant metabolite		2012201212.0low000010
solanesol
1
nonaprenol;
primary alcohol		plant metabolite2012201212.0low000010
avicularin
1
alpha-L-arabinofuranoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		hepatoprotective agent;
plant metabolite		1996199628.0low001000
hibifolin
1
2011201113.0medium000010
(1S,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-[oxo-(3,4,5-trimethoxyphenyl)methoxy]-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid methyl ester
1
yohimban alkaloid2012201212.0high000010
n-caproylsphingosine
1
N-acylsphingosine2012201212.0low000010
monorden
1
cyclic ketone;
enone;
epoxide;
macrolide antibiotic;
monochlorobenzenes;
phenols		antifungal agent;
metabolite;
tyrosine kinase inhibitor		2012201212.0low000010
ginkgolide b
1
2012201212.0low000010
homatropine hydrobromide, (endo-(+-)-isomer)
1
2012201212.0low000010
hydrocotarnine hydrobromide
1
2012201212.0low000010
salsolinol hydrobromide
1
2012201212.0medium000010
lasalocid sodium
1
benzoates;
organic sodium salt		coccidiostat;
ionophore		2012201212.0low000010
sclerotiorin
1
azaphilone2012201212.0low000010
himbacine
1
gamma-lactone;
organic heterotricyclic compound;
piperidine alkaloid		muscarinic antagonist2012201212.0low000010
ebelactone b
1
2012201212.0low000010
3-o-methylbutein
1
chalcones2012201212.0medium000010
thermozymocidin
1
alpha-amino fatty acid;
hydroxy monocarboxylic acid;
non-proteinogenic alpha-amino acid;
sphingoid		antifungal agent;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor;
fungal metabolite;
immunosuppressive agent		2012201212.0low000010
marein
1
flavonoids;
glycoside		2012201212.0low000010
4,5-di-O-caffeoylquinic acid
1
quinic acid201820186.0low000010
indigo carmine
1
201820186.0low000010
beta-escin
1
triterpenoid saponin201820186.0low000010
hydroxyachillin
1
gamma-lactone2012201212.0medium000010
butylscopolammonium bromide
1
2012201212.0low000010
fumagillin
1
antibiotic antifungal drug;
carboxylic ester;
dicarboxylic acid monoester;
meroterpenoid;
organooxygen heterocyclic antibiotic;
spiro-epoxide		angiogenesis inhibitor;
antibacterial drug;
antimicrobial agent;
antiprotozoal drug;
fungal metabolite;
methionine aminopeptidase 2 inhibitor		2012201212.0low000010
artesunate
1
artemisinin derivative;
cyclic acetal;
dicarboxylic acid monoester;
hemisuccinate;
semisynthetic derivative;
sesquiterpenoid		antimalarial;
antineoplastic agent;
ferroptosis inducer		2012201212.0low000010
anisodamine
1
2012201212.0medium000010
eupatorin-5-methyl ether
1
1996199628.0high001000
bufalin
1
14beta-hydroxy steroid;
3beta-hydroxy steroid		animal metabolite;
anti-inflammatory agent;
antineoplastic agent;
cardiotonic drug		2012201212.0low000010
alpha-solanine
1
glycoalkaloid;
organic heterohexacyclic compound;
steroid saponin;
trisaccharide derivative		antineoplastic agent;
apoptosis inducer;
phytotoxin;
plant metabolite		2012201212.0medium000010
apigenin-7-o-rutinoside
1
2012201212.0medium000010
gambogic acid
1
pyranoxanthonesmetabolite2012201212.0low000010
bn 52020
1
2012201212.0low000010
carmine
1
C-glycosyl compound;
monocarboxylic acid;
tetrahydroxyanthraquinone		animal metabolite;
histological dye		2012201212.0low000010
bavachinin
1
flavanones2012201212.0low000010
grayanotoxin iii
1
2012201212.0low000010
Dihydrotanshinone I
1
abietane diterpenoidanticoronaviral agent2012201212.0low000010
calcimycin
1
benzoxazole2012201212.0low000010
cinobufagin
1
steroid lactone2012201212.0low000010
atropine sulfate
1
2012201212.0low000010
cannogenin thevetoside
1
cardenolide glycoside2012201212.0low000010
eriodictyol 7-O-beta-D-glucopyranoside
1
beta-D-glucoside;
flavanone glycoside;
monosaccharide derivative;
trihydroxyflavanone		plant metabolite;
radical scavenger		2012201212.0medium000010
15-deoxygoyazensolide
1
201820186.0medium000010
hypocrellin a
1
2012201212.0low000010
dihydrorobinetin
2
1996201220.0high001010
monensin
1
2012201212.0medium000010
minocycline
1
2012201212.0low000010
dicumarol
1
hydroxycoumarinanticoagulant;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
Hsp90 inhibitor;
vitamin K antagonist		2012201212.0low000010
citrinin
1
2012201212.0low000010
vulpinic acid
1
butenolide2012201212.0low000010
ajmaline
1
2012201212.0medium000010
agathic acid
1
201820186.0low000010
rifampin
2
cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor		2012201610.0low000020
alpha-cyclopiazonic acid
1
alpha-cyclopiazonic acids2012201212.0low000010
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
glycerol
1
alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent		201920195.0low000010
sulfur dioxide
1
sulfur oxideEscherichia coli metabolite;
food bleaching agent;
refrigerant		2006200618.0low000100
indomethacin
1
aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic		201720177.0low000010
isoproterenol
1
catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent		201820186.0low000010
tolbutamide
1
N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker		2014201410.0low000010
catechin
1
catechinantioxidant;
plant metabolite		2007200717.0low000100
3-hydroxyflavone
11
flavonols;
monohydroxyflavone		2005202014.0low300740
ampelopsin
1
dihydromyricetin;
secondary alpha-hydroxy ketone		antineoplastic agent;
antioxidant;
metabolite		202020204.0low000010
pectins
1
D-galactopyranuronic acid201520159.0low100010
prostaglandin d2
1
prostaglandins Dhuman metabolite;
mouse metabolite		202120213.0low000001
digoxin
1
cardenolide glycoside;
steroid saponin		anti-arrhythmia drug;
cardiotonic drug;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
epitope		201820186.0low000010
lincomycin
1
carbohydrate-containing antibiotic;
L-proline derivative;
monocarboxylic acid amide;
pyrrolidinecarboxamide;
S-glycosyl compound		antimicrobial agent;
bacterial metabolite		2007200717.0low000100
quercetin 3-o-glucuronide
1
beta-D-glucosiduronic acid;
quercetin O-glycoside		antidepressant;
antioxidant;
metabolite		201920195.0low000010
quercetin
38
7-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger		200520229.2low7009227
apigenin
1
trihydroxyflavoneantineoplastic agent;
metabolite		2007200717.0low000100
calcitriol
1
D3 vitamins;
hydroxycalciol;
triol		antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical		201620168.0low000010
leukotriene c4
1
leukotrienebronchoconstrictor agent;
human metabolite;
mouse metabolite		202120213.0low000001
stigmasterol
1
3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
phytosterols;
stigmastane sterol		plant metabolite201920195.0low000010
rutin
2
disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone		antioxidant;
metabolite		2013201510.0low000020
kaempferol
3
7-hydroxyflavonol;
flavonols;
tetrahydroxyflavone		antibacterial agent;
geroprotector;
human blood serum metabolite;
human urinary metabolite;
human xenobiotic metabolite;
plant metabolite		201320169.3low000030
fisetin
1
3'-hydroxyflavonoid;
7-hydroxyflavonol;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
metabolite;
plant metabolite		2007200717.0low000100
galangin
3
7-hydroxyflavonol;
trihydroxyflavone		antimicrobial agent;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
plant metabolite		200720209.7low000120
3-methylquercetin
17
7-hydroxyflavonol;
monomethoxyflavone;
tetrahydroxyflavone		anticoagulant;
EC 1.14.18.1 (tyrosinase) inhibitor;
metabolite		2006202110.6low7005111
kaempferide
1
7-hydroxyflavonol;
monomethoxyflavone;
trihydroxyflavone		antihypertensive agent;
metabolite		2013201311.0low000010
morin
1
7-hydroxyflavonol;
pentahydroxyflavone		angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent		201620168.0low000010
myricetin
1
7-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite		201620168.0low000010
rhamnetin
2
monomethoxyflavone;
tetrahydroxyflavone		anti-inflammatory agent;
antioxidant;
metabolite		2007202010.5low000110
syringetin
2
3',5'-dimethoxyflavone;
3'-methoxyflavones;
7-hydroxyflavonol;
dimethoxyflavone;
tetrahydroxyflavone		metabolite;
platelet aggregation inhibitor		201620206.0medium000020
(3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
1
(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid2014201410.0low000010
quercetin 3'-sulfate
1
201920195.0low000010
isorhamnetin-3-o-neohesperidoside
1
2005200519.0low000100
isoquercitrin
1
2006200618.0low000100
ascorbic acid
1
ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent		2012201212.0low000010
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Acute Confusional Senile Dementia0
1
202020204.0low000010
Alzheimer Disease0
1
202020204.0low000010
Amyloid Deposits0
1
202020204.0low000010
Blood Poisoning0
1
201820186.0low000010
Body Weight0
1
201520159.0low000010
Breast Cancer0
1
202220222.0low000001
Breast Neoplasms0
1
202220222.0low000001
Cancer of Liver0
1
201920195.0low000010
Cardiac Hypertrophy0
1
201920195.0low000010
Cardiac Remodeling, Ventricular0
1
201920195.0low000010
Cardiomegaly0
1
201920195.0low000010
Cirrhosis0
1
201920195.0low000010
Fibrosarcoma0
1
202120213.0low000001
Fibrosis0
1
201920195.0low000010
Infections, Staphylococcal0
1
202220222.0low000001
Inflammation0
3
2008201811.0medium200120
Innate Inflammatory Response0
3
2008201811.0medium200120
Invasiveness, Neoplasm0
1
202120213.0low000001
Leucocythaemia0
1
2014201410.0low000010
Leukemia0
1
2014201410.0low000010
Liver Neoplasms0
1
201920195.0low000010
Overweight0
1
2013201311.0low100010
Pregnancy0
1
201520159.0low000010
Sepsis0
1
201820186.0low000010
Staphylococcal Infections0
1
202220222.0low000001

Safety/Toxicity (1)

ArticleYear
The minor structural difference between the antioxidants quercetin and 4'O-methylquercetin has a major impact on their selective thiol toxicity.
International journal of molecular sciences, , Apr-30, Volume: 15, Issue:5		2014

Bioavailability (9)

ArticleYear
Bioavailability of the flavonol quercetin in neonatal calves after oral administration of quercetin aglycone or rutin.
Journal of dairy science, , Volume: 98, Issue:6		2015
Quercetin bioavailability is associated with inadequate plasma vitamin C status and greater plasma endotoxin in adults.
Nutrition (Burbank, Los Angeles County, Calif.), , Volume: 30, Issue:11-12
Dietary flavonoids modulate CYP2C to improve drug oral bioavailability and their qualitative/quantitative structure-activity relationship.
The AAPS journal, , Volume: 16, Issue:2		2014
Bioavailability of quercetin from its aglycone and its glucorhamnoside rutin in lactating dairy cows after intraduodenal administration.
Journal of dairy science, , Volume: 96, Issue:4		2013
Dietary fat increases quercetin bioavailability in overweight adults.
Molecular nutrition & food research, , Volume: 57, Issue:5		2013
Effects of O-methylated metabolites of quercetin on oxidative stress, thermotolerance, lifespan and bioavailability on Caenorhabditis elegans.
Food & function, , Volume: 2, Issue:8		2011
Enriched cereal bars are more effective in increasing plasma quercetin compared with quercetin from powder-filled hard capsules.
The British journal of nutrition, , Volume: 107, Issue:4		2012
Tissue distribution of quercetin in pigs after long-term dietary supplementation.
The Journal of nutrition, , Volume: 138, Issue:8		2008
Red wine alcohol promotes quercetin absorption and directs its metabolism towards isorhamnetin and tamarixetin in rat intestine in vitro.
British journal of pharmacology, , Volume: 147, Issue:7		2006

Dosage (1)

ArticleYear
Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans.
The Journal of nutrition, , Volume: 138, Issue:9		2008