Assay ID | Title | Year | Journal | Article |
AID1161858 | Induction of apoptosis in human KB cells assessed as early apoptotic cells level at 10 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 7.08%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161839 | Antiproliferative activity against human HL7702 cells after 48 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID426932 | Cytotoxicity against human SH-SY5Y cells after 48 hrs by SRB method | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6
| ent-Kaurane diterpenoids from Isodon pharicus. |
AID1692275 | Antagonist activity at GP6 in human platelet assessed as reduction in CRP-induced platelet-aggregation preincubated for 10 mins followed by collagen stimulation by aggregometry | 2020 | Journal of medicinal chemistry, 11-12, Volume: 63, Issue:21
| Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. |
AID426933 | Cytotoxicity against human PC3 cells after 48 hrs by SRB method | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6
| ent-Kaurane diterpenoids from Isodon pharicus. |
AID1161837 | Antiproliferative activity against human KB cells after 48 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161860 | Induction of apoptosis in human KB cells assessed as necrotic cells level at 10 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 3.23%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID426931 | Cytotoxicity against human A549 cells after 48 hrs by SRB method | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6
| ent-Kaurane diterpenoids from Isodon pharicus. |
AID1161865 | Chemical stability in 10 mM pH 7.4 PBS buffer assessed as parent compound remaining at 1 uM at 37 degC after 24 hrs by HPLC method | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161864 | Induction of apoptosis in human KB cells assessed as necrotic cells level at 20 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 3.23%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID426934 | Cytotoxicity against human MCF7 cells after 48 hrs by SRB method | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6
| ent-Kaurane diterpenoids from Isodon pharicus. |
AID1161855 | Induction of apoptosis in human KB cells assessed as late apoptotic cells level at 5 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 2.26%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161861 | Induction of apoptosis in human KB cells assessed as viable cells level at 20 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 87.4%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161840 | Induction of apoptosis in human KB cells after 48 hrs by Annexin V and propidium iodide staining based flow cytometry | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161867 | Prodrug conversion in human KB cells lysates assessed as formation of cysteine conjugates at 500 uM in presence of 10 mM cysteine by LC-HRMS method | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161854 | Induction of apoptosis in human KB cells assessed as early apoptotic cells level at 5 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 7.08%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161838 | Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161866 | Stability in 80% rat plasma assessed as parent compound remaining at 1 uM at 37 degC after 24 hrs by HPLC method | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161835 | Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID426930 | Cytotoxicity against human NB4 cells after 48 hrs by SRB method | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6
| ent-Kaurane diterpenoids from Isodon pharicus. |
AID1692271 | Inhibition of ADP-induced platelet aggregation in rabbit platelet suspension preincubated for 10 mins followed by ADP stimulation by turbidimetric method | 2020 | Journal of medicinal chemistry, 11-12, Volume: 63, Issue:21
| Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. |
AID1161863 | Induction of apoptosis in human KB cells assessed as late apoptotic cells level at 20 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 2.26%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161859 | Induction of apoptosis in human KB cells assessed as late apoptotic cells level at 10 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 2.26%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161834 | Antiproliferative activity against mouse B16 cells after 48 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1692273 | Inhibition of PAF-induced platelet aggregation in rabbit platelet suspension preincubated for 10 mins followed by PAF stimulation by turbidimetric method | 2020 | Journal of medicinal chemistry, 11-12, Volume: 63, Issue:21
| Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. |
AID1161857 | Induction of apoptosis in human KB cells assessed as viable cells level at 10 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 87.4%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1692274 | Antagonist activity at GP6 in human platelet assessed as reduction in collagen-induced platelet-aggregation preincubated for 10 mins followed by collagen stimulation by aggregometry | 2020 | Journal of medicinal chemistry, 11-12, Volume: 63, Issue:21
| Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. |
AID1692272 | Inhibition of arachidonic acid-induced platelet aggregation in rabbit platelet suspension preincubated for 10 mins followed by AA stimulation by turbidimetric method | 2020 | Journal of medicinal chemistry, 11-12, Volume: 63, Issue:21
| Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. |
AID1161869 | Retention time of the compound in human KB cells lysates treated with 500 uM oridonin in presence of 10 mM cysteine by LC-HRMS method | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161856 | Induction of apoptosis in human KB cells assessed as necrotic cells level at 5 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 3.23%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161862 | Induction of apoptosis in human KB cells assessed as early apoptotic cells level at 20 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 7.08%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161836 | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161853 | Induction of apoptosis in human KB cells assessed as viable cells level at 5 uM after 48 hrs by Annexin V and propidium iodide staining based flow cytometry (Rvb = 87.4%) | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
AID1161833 | Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |