peoniflorin and Sepsis

peoniflorin has been researched along with Sepsis* in 1 studies

Other Studies

1 other study(ies) available for peoniflorin and Sepsis

Article	Year
[Paeoniflorin Improves Acute Lung Injury in Sepsis by Activating Nrf2/Keap1 Signaling Pathway]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2020, Volume: 51, Issue:5 To investigate the effect of paeoniflorin (PF) on sepsis-induced acute lung injury and its relationship with nuclear factor erythyroid 2-related factor 2 (Nrf2)/Kelch-like ECH2 associated protein 1 (Keap1) signaling pathway.. Compared with Sham group, the sepsis symptoms in Model group were more serious, severe inflammatory infiltration in lung tissue, macrophages and interstitial enlargement, and the contents of pro-inflammatory factors IL-1β, TNF-α, IL-6 and oxidative index MDA in lung tissues were significantly increased (. PF can reduce oxidative stress and inflammation by activating Nrf2/Keap1 signaling pathway, and improve sepsis-induced acute lung injury. Topics: Acute Lung Injury; Animals; Glucosides; Kelch-Like ECH-Associated Protein 1; Monoterpenes; NF-E2-Related Factor 2; Oxidative Stress; Rats; Sepsis; Signal Transduction	2020

Article

Year

[Paeoniflorin Improves Acute Lung Injury in Sepsis by Activating Nrf2/Keap1 Signaling Pathway].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2020, Volume: 51, Issue:5

To investigate the effect of paeoniflorin (PF) on sepsis-induced acute lung injury and its relationship with nuclear factor erythyroid 2-related factor 2 (Nrf2)/Kelch-like ECH2 associated protein 1 (Keap1) signaling pathway.. Compared with Sham group, the sepsis symptoms in Model group were more serious, severe inflammatory infiltration in lung tissue, macrophages and interstitial enlargement, and the contents of pro-inflammatory factors IL-1β, TNF-α, IL-6 and oxidative index MDA in lung tissues were significantly increased (. PF can reduce oxidative stress and inflammation by activating Nrf2/Keap1 signaling pathway, and improve sepsis-induced acute lung injury.

Topics: Acute Lung Injury; Animals; Glucosides; Kelch-Like ECH-Associated Protein 1; Monoterpenes; NF-E2-Related Factor 2; Oxidative Stress; Rats; Sepsis; Signal Transduction

2020