peoniflorin has been researched along with Sepsis* in 1 studies
1 other study(ies) available for peoniflorin and Sepsis
Article | Year |
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[Paeoniflorin Improves Acute Lung Injury in Sepsis by Activating Nrf2/Keap1 Signaling Pathway].
To investigate the effect of paeoniflorin (PF) on sepsis-induced acute lung injury and its relationship with nuclear factor erythyroid 2-related factor 2 (Nrf2)/Kelch-like ECH2 associated protein 1 (Keap1) signaling pathway.. Compared with Sham group, the sepsis symptoms in Model group were more serious, severe inflammatory infiltration in lung tissue, macrophages and interstitial enlargement, and the contents of pro-inflammatory factors IL-1β, TNF-α, IL-6 and oxidative index MDA in lung tissues were significantly increased (. PF can reduce oxidative stress and inflammation by activating Nrf2/Keap1 signaling pathway, and improve sepsis-induced acute lung injury. Topics: Acute Lung Injury; Animals; Glucosides; Kelch-Like ECH-Associated Protein 1; Monoterpenes; NF-E2-Related Factor 2; Oxidative Stress; Rats; Sepsis; Signal Transduction | 2020 |