Page last updated: 2024-11-13

blood group a trisaccharide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

alpha-D-GalpNAc-(1->3)-[alpha-L-Fucp-(1->2)]-beta-D-Galp : A branched amino trisaccharide consisting of beta-D-galactose having an alpha-L-fucosyl residue at the 2-position and an N-acetyl-alpha-D-galactosaminyl residue at the 3-position. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID49852448
CHEBI ID61012
SCHEMBL ID6244373
MeSH IDM0265695

Synonyms (24)

Synonym
alpha-l-fucp-(1->2)-[alpha-d-galpnac-(1->3)]-beta-d-galp
alpha-d-n-acetylgalactosaminyl-(1->3)-[alpha-l-fucosyl-(1->2)]-beta-d-galactose
alpha-d-galnac-(1->3)-[alpha-l-fuc-(1->2)]-beta-d-gal
alphagalnac1->3(alphafuc1->2)betagal
2-acetamido-2-deoxy-alpha-d-galactopyranosyl-(1->3)-[alpha-l-fucopyranosyl-(1->2)]-beta-d-galactopyranose
2-acetamido-2-deoxy-alpha-d-galactopyranosyl-(1->3)-[6-deoxy-alpha-l-galactopyranosyl-(1->2)]-beta-d-galactopyranose
alpha-d-galpnac-(1->3)-[alpha-l-fucp-(1->2)]-beta-d-galp
alpha-l-fucosyl-(1->2)-[alpha-d-n-acetylgalactosaminyl-(1->3)]-beta-d-galactose
galnaca1-3(fuca1-2)galb
blood group a trisaccharide
blood group a type 1 trisaccharide
galnacalpha1-3(fucalpha1-2)galbeta
alpha-l-fuc-(1->2)-[alpha-d-galnac-(1->3)]-beta-d-gal
2-acetamido-2-deoxy-alpha-d-galactosyl-(1->3)-[6-deoxy-alpha-l-galactosyl-(1->2)]-beta-d-galactose
n-acetyl-alpha-d-galactosaminyl-(1->3)-[alpha-l-fucosyl-(1->2)]-beta-d-galactose
galnacalpha1,3(fucalpha1,2)galbeta
galnacalpha1->3(fucalpha1->2)galbeta
CHEBI:61012 ,
galnac1-3(fucalpha1-2)galbeta
EPITOPE ID:140124
2W7Y
SCHEMBL6244373
Q27130564
n-[(2r,3r,4r,5r,6r)-2-{[(2r,3r,4s,5s,6r)-2,5-dihydroxy-6-(hydroxymethyl)-3-{[(2s,3s,4r,5s,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-4-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
antigenAny substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC).
epitopeThe biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
alpha-D-GalpNAc-(1->3)-[alpha-L-Fucp-(1->2)]-D-GalpA branched amino trisaccharide consisting of D-galactose having an alpha-L-fucosyl residue at the 2-position and an N-acetyl-alpha-D-galactosaminyl residue at the 3-position.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, PROBABLE SUGAR ABC TRANSPORTER, SUGAR-BINDING PROTEINStreptococcus pneumoniae SP3-BS71Kd0.83000.83000.83000.8300AID977611
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID977611Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB2009Journal of molecular biology, May-01, Volume: 388, Issue:2
Blood group antigen recognition by a solute-binding protein from a serotype 3 strain of Streptococcus pneumoniae.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (23)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's5 (21.74)18.2507
2000's13 (56.52)29.6817
2010's4 (17.39)24.3611
2020's1 (4.35)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.41

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.41 (24.57)
Research Supply Index3.18 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.41)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews6 (26.09%)6.00%
Case Studies4 (17.39%)4.05%
Observational0 (0.00%)0.25%
Other13 (56.52%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]