Page last updated: 2024-11-05

tolazoline and Sepsis

tolazoline has been researched along with Sepsis in 2 studies

Tolazoline: A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
tolazoline : A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.

Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

Research Excerpts

ExcerptRelevanceReference
"The effect of tolazoline (Tz) on mesenteric blood flow was evaluated in a piglet model of group B streptococcal (GBS) sepsis."7.67Nonhomogeneous redistribution of mesenteric blood flow after tolazoline during group B streptococcal sepsis in piglets. ( Meadow, WL; Meus, PJ, 1985)
"The effect of tolazoline (Tz) on mesenteric blood flow was evaluated in a piglet model of group B streptococcal (GBS) sepsis."3.67Nonhomogeneous redistribution of mesenteric blood flow after tolazoline during group B streptococcal sepsis in piglets. ( Meadow, WL; Meus, PJ, 1985)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meadow, WL2
Meus, PJ2

Other Studies

2 other studies available for tolazoline and Sepsis

ArticleYear
Hemodynamic consequences of tolazoline in neonatal group B streptococcal bacteremia: an animal model.
    Pediatric research, 1984, Volume: 18, Issue:10

    Topics: Animals; Animals, Newborn; Blood Pressure; Cardiac Output; Disease Models, Animal; Dose-Response Rel

1984
Nonhomogeneous redistribution of mesenteric blood flow after tolazoline during group B streptococcal sepsis in piglets.
    Developmental pharmacology and therapeutics, 1985, Volume: 8, Issue:4

    Topics: Animals; Animals, Newborn; Cardiac Output; Disease Models, Animal; Sepsis; Splanchnic Circulation; S

1985