Compounds > methallyl sulfonate
Page last updated: 2024-11-13

methallyl sulfonate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID23663624
CHEMBL ID3181810
SCHEMBL ID127250
MeSH IDM0157471

Synonyms (50)

Synonym
ec 216-341-5
einecs 216-341-5
ai3-16415
ara0t9zu4a ,
unii-ara0t9zu4a
nsc 2253
2-propene-1-sulfonic acid, 2-methyl-, sodium salt (1:1)
sodium 2-methylprop-2-ene-1-sulphonate
nsc-2253
methallyl sulfonate
1561-92-8
2-methyl-2-propene-1-sulfonic acid, sodium salt
2-propene-1-sulfonic acid, 2-methyl-, sodium salt
sodium 2-methyl-2-propenesulfonate
methallylsulfonic acid, sodium salt
sodium methallylsulfonate
acetic acid; triphenylstibane
methallylsulfonic acid sodium salt
M1408
2-methyl-2-propene-1-sulfonic acid sodium salt
sodium 2-methyl-2-propene-1-sulfonate
194810-55-4
A809722
sodium 2-methylprop-2-ene-1-sulfonate
cas-1561-92-8
tox21_301717
dtxcid0024840
dtxsid2044840 ,
NCGC00256079-01
sodium methallyl sulfonate
C20360
AKOS015962099
FT-0633668
AKOS015900376
c4h7nao3s
SZHIIIPPJJXYRY-UHFFFAOYSA-M
SCHEMBL127250
CHEMBL3181810
J-524269
sodium methallyl sulfonate (solid)
mfcd00065344
J-009282
sodium methallyl sulfonate(35%)
2-methyl-2-propene-1-sulfonic acid sodium
sodium;2-methylprop-2-ene-1-sulfonate
Q27274084
sodium2-methylprop-2-ene-1-sulfonate
sodiummethallylsulfonate
AS-80425
EN300-26274851

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" An increase in total clearance and a decrease in elimination half-life were observed to the extent that the patient's creatinine clearance was higher."( Meropenem and continuous renal replacement therapy: in vitro permeability of 2 continuous renal replacement therapy membranes and influence of patient renal function on the pharmacokinetics in critically ill patients.
Arzuaga, A; Corral, E; Gascón, AR; Isla, A; Maynar, J; Pedraz, JL; Sánchez-Izquierdo, JA, 2005)		0.33

Dosage Studied

ExcerptRelevanceReference
" The dose-response curve of the binding to this type of membrane was linear."( Hemodialysis membrane biocompatibility: the case of erythropoietin.
Cheung, AK; DeSpain, M; Hohnholt, M; Leypoldt, JK, 1991)		0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
AR proteinHomo sapiens (human)Potency11.03370.000221.22318,912.5098AID743035; AID743036
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's3 (37.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.50 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index5.04 (4.65)
Search Engine Demand Index30.30 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (29.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (11.11%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational1 (11.11%)0.25%
Other7 (77.78%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
urea
pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.		2.1510isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
4-phenolsulfonic acid
4-hydroxybenzenesulfonic acid : An arenesulfonic acid that is phenol substituted by a sulfo group at C-4.		1.9710arenesulfonic acid
acrylic acid
acrylic acid: RN given refers to parent cpd. acrylic acid : A alpha,beta-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group.		1.9710alpha,beta-unsaturated monocarboxylic acidmetabolite
acrylonitrile
[no description available]		4.8371aliphatic nitrile;
volatile organic compound		antifungal agent;
carcinogenic agent;
fungal metabolite;
mutagen;
polar aprotic solvent
an-69
AN-69: copolymer of acrylonitrile & sodium methallylsulfonate used in hemodialysis		4.0731
cellulose triacetate
cellulose triacetate: for hemodialysis filtration		2.1510
meropenem
Meropenem: A thienamycin derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of bacterial infections, including infections in immunocompromised patients.. meropenem : A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively.		3.4111alpha,beta-unsaturated monocarboxylic acid;
carbapenemcarboxylic acid;
organic sulfide;
pyrrolidinecarboxamide		antibacterial agent;
antibacterial drug;
drug allergen
losartan potassium
Erythropoietin: Glycoprotein hormone, secreted chiefly by the KIDNEY in the adult and the LIVER in the FETUS, that acts on erythroid stem cells of the BONE MARROW to stimulate proliferation and differentiation.		1.9710
cellulose
DEAE-Cellulose: Cellulose derivative used in chromatography, as ion-exchange material, and for various industrial applications.		2.730glycoside
4-sulfophenylmethallyl ether
[no description available]		1.9710
acetylcellulose
acetylcellulose: coating compound. cellulose acetate : A glucan derivative obtained through the esterification of cellulose by acetic anhydride or acetic acid, resulting in the substitution of some of the hydroxy groups of cellulose by acetyl groups. It is used in a variety of applications including base material for photographic film, clothing, membrane filters, coatings, food packaging, and as a frame material for eyeglasses.		1.9810
ConditionIndicatedRelationship StrengthStudiesTrials
Blood Poisoning
[description not available]		02.7620
Acute Kidney Failure
[description not available]		02.610
Experimental Lung Inflammation
Inflammation of any part, segment or lobe, of the lung parenchyma.		02.610
Pneumonia
Infection of the lung often accompanied by inflammation.		07.610
Sepsis
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.		07.7620
Acute Kidney Injury
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.		02.610
Endotoxin Shock
[description not available]		02.2510
Shock, Septic
Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.		02.2510
Primary Peritonitis
[description not available]		02.2510
Peritonitis
INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.		07.2510
Chronic Kidney Failure
[description not available]		02.1510
Kidney Failure, Chronic
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.		02.1510
Kidney Diseases
Pathological processes of the KIDNEY or its component tissues.		03.4111
Leukocytopenia
[description not available]		01.9810
Leukopenia
A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).		01.9810