oxytetracycline--anhydrous and Sepsis

Topics: Adult; Anti-Bacterial Agents; Bacteriuria; Drug Resistance, Microbial; Female; Humans; Klebsiella Infections; Oxytetracycline; Pregnancy; Pregnancy Complications, Infectious; Pyelonephritis; Sepsis

The prophylactic effect of systemic metronidazole on infectious complications following elective colo-rectal surgery was compared with the prophylactic effect of oxytetracycline. Allocation to receive metronidazole or oxytetracycline was random. A total of 137 patients were accepted for the trial, 67 receiving metronidazole and 70 oxytetracycline. The numbers of abdominal wound infections, intra-abdominal infections, fever and deaths were few in both groups, and the differences statistically insignificant. Clinically significant side effects of the antimicrobial agents were not observed. The influence of the antimicrobial agents on colonic flora was also studied. No significant difference in the effect on colonic anaerobic flora was demonstrated, whereas the aerobic flora was significantly suppressed by oxytetracycline. It is concluded that systemic metronidazole, although acting solely on the anaerobic flora, is as effective as oxytetracycline in preventing postoperative infectious complications following elective colo-rectal surgery. The prophylactic use of metronidazole is advocated.

Topics: Administration, Oral; Aged; Clinical Trials as Topic; Colectomy; Colonic Diseases; Colostomy; Female; Humans; Male; Metronidazole; Middle Aged; Oxytetracycline; Rectal Diseases; Sepsis; Surgical Wound Infection

One hundred and ninety-six housed pregnant ewes were fed poor quality silage for two days. Ewes are reluctant to eat the silage and within 48 hours they became dull and developed diarrhoea and lameness. Despite treatment with antibiotics and calcium borogluconate 19 ewes died, more than 60 developed vaginal discharges and at lambing 94 ewes were barren. Six developed nervous signs and two of these died, one with lesions typical of listeric encephalitis. Post mortem lesions and the isolation of Listeria monocytogenes type 1/2 from lung, liver, spleen and kidney are described. L monocytogenes was also isolated from blood samples from live ewes. The estimated gross financial loss to the farmer was 5130 pounds or, for the flock, 26 pounds per ewe.

Topics: Abortion, Veterinary; Animal Feed; Animals; Encephalitis; Female; Listeria monocytogenes; Listeriosis; Oxytetracycline; Pregnancy; Sepsis; Sheep; Sheep Diseases

Some 115 R- and 143 S-streptococcal strains were isolated from 258 pigs that had died or been killed for disease, between 1969 and 1973. They were cultured and biochemically tested for sensitivity to chemotherapeutics. All R- and S-strains were of normal sensitivity to penicillin and, with few exceptions, to chloramphenicol and oxytetracycline as well. Most of the strains caused primary Sc.-infection, such as septicaemia, leptomeningitis, endocarditis, and arthritis. R-Sc.-infections were contracted mainly by store pigs and animals in advenced age, while S-Sc.-infections affected mainly piglets.

Topics: Animals; Arthritis; Chloramphenicol; Endocarditis; Meningitis; Oxytetracycline; Penicillins; Sepsis; Streptococcal Infections; Streptococcus; Swine; Swine Diseases

Topics: Ampicillin; Animals; Animals, Newborn; Anti-Bacterial Agents; Bronchopneumonia; Chloramphenicol; Corneal Ulcer; Diarrhea; Enteritis; Female; Horse Diseases; Horses; Male; Oxytetracycline; Penicillin Resistance; Penicillins; Pleurisy; Pneumonia; Pneumonia, Aspiration; Pneumonia, Pneumocystis; Postoperative Complications; Salmonella Infections, Animal; Sepsis; Streptococcal Infections; Uterine Diseases

A case of septicaemia due to Yersinia enterocolitica serotype 3, biotype 4, in a non-compromised host is described. The patient showed severe signs of gram-negative septicaemia. Treatment with sulphamethoxazole-trimethoprim (Bactrim) was unsuccessful in spite of full sensitivity, bactericidal and synergistic effects in vitro. Tetracycline gave full restitution.

Topics: Aged; Humans; Male; Oxytetracycline; Penicillin G; Penicillin G Procaine; Sepsis; Sulfamethoxazole; Trimethoprim; Yersinia

Topics: Animals; Blood; Blood Proteins; Blood Sedimentation; Blood Urea Nitrogen; Dog Diseases; Dogs; Ehrlichia; Hematocrit; Hemoglobins; Male; Oxytetracycline; Rickettsiaceae Infections; Sepsis

Topics: Adult; Aged; Doxycycline; Enterobacter; Escherichia; Escherichia coli; Female; Humans; Injections, Intravenous; Klebsiella; Male; Middle Aged; Oxytetracycline; Proteus; Proteus mirabilis; Pseudomonas; Sepsis; Staphylococcus; Streptococcus; Streptococcus pneumoniae; Surgical Wound Infection; Urinary Tract Infections

Topics: Acute Disease; Adult; Chloramphenicol; Humans; Middle Aged; Nephrectomy; Oxytetracycline; Pyelonephritis; Sepsis; Shock, Septic; Suppuration; Time Factors; Uremia

Topics: Adjuvants, Immunologic; Animals; Bacterial Vaccines; Buffaloes; Cattle; Cattle Diseases; Hemorrhage; Malaysia; Oils; Oxytetracycline; Pasteurella Infections; Sepsis; Sulfamethazine; Vaccination

Topics: Anemia, Aplastic; Animals; Blood Platelets; Blood Sedimentation; Dog Diseases; Dogs; Female; Hemorrhage; Leukopenia; Male; Oxytetracycline; Rickettsia; Rickettsiaceae Infections; Sepsis; Species Specificity; Thiosemicarbazones; Thrombocytopenia

Topics: Ampicillin; Anti-Bacterial Agents; Carbenicillin; Cephalothin; Chloramphenicol; Endocarditis, Bacterial; Enterobacteriaceae Infections; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Nalidixic Acid; Oxytetracycline; Penicillin Resistance; Polymyxins; Sepsis; Serratia marcescens; Surgical Wound Infection; Urinary Tract Infections

Topics: Ampicillin; Anti-Bacterial Agents; Bacteria; Bacteriuria; Carbenicillin; Chloramphenicol; Depression, Chemical; Drug Antagonism; Drug Synergism; Erythromycin; Escherichia coli; Exudates and Transudates; Humans; Kanamycin; Methacycline; Novobiocin; Oxytetracycline; Proteus; Pseudomonas aeruginosa; Rifampin; Ristocetin; Sepsis; Sputum; Staphylococcus; Surgical Wound Infection

Topics: Anti-Infective Agents, Local; Enterobacteriaceae Infections; Epistaxis; Focal Infection; Humans; Oxytetracycline; Polymyxins; Sepsis; Staphylococcal Infections; Tampons, Surgical

Topics: Administration, Oral; Animals; Chlortetracycline; Depression, Chemical; Doxycycline; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Humans; Kinetics; Methacycline; Oxytetracycline; Sepsis; Staphylococcal Infections; Staphylococcus; Tetracycline

Topics: Aged; Campylobacter fetus; Female; Humans; Leukemia, Lymphoid; Oxytetracycline; Sepsis; Vibrio Infections

Topics: Anti-Bacterial Agents; Chloramphenicol; Chlortetracycline; Depression, Chemical; Erythromycin Ethylsuccinate; Humans; Kanamycin; Microbial Sensitivity Tests; Neomycin; Oleandomycin; Oxytetracycline; Penicillin G; Penicillin Resistance; Penicillins; Sepsis; Staphylococcus; Streptomycin; Tetracycline

Topics: Abortion, Septic; Diagnosis, Differential; Female; Hepatitis A; Humans; Hysterectomy; Oxytetracycline; Penicillins; Pregnancy; Prognosis; Renal Dialysis; Sepsis; Shock, Septic; Shwartzman Phenomenon; Time Factors

Topics: Aerosols; Animals; Antifungal Agents; Bacitracin; Biopsy; Debridement; Guinea Pigs; Neomycin; Oxytetracycline; Polymyxins; Pseudomonas; Rabbits; Sepsis; Streptococcus; Wound Healing; Wound Infection; Wounds and Injuries

Topics: Dentistry; Mouth; Oxytetracycline; Sepsis

Topics: Animals; Dihydrostreptomycin Sulfate; Oxytetracycline; Penicillins; Poultry Diseases; Sepsis; Serositis

Topics: Ampicillin; Anti-Bacterial Agents; Bacteriuria; Cephalosporins; Cephalothin; Chloramphenicol; Chlortetracycline; Demeclocycline; Escherichia coli; Gentamicins; Humans; Kanamycin; Klebsiella; Methacycline; Microbial Sensitivity Tests; Oxytetracycline; Penicillin G; Penicillins; Polymyxins; Proteus; Pseudomonas aeruginosa; Sepsis; Serratia; Streptomycin; Tetracycline

Topics: Anemia; Chloramphenicol; Chlorpromazine; Eye; Glutethimide; Herpes Zoster; Herpes Zoster Ophthalmicus; Hodgkin Disease; Lung Abscess; Mechlorethamine; Meprobamate; Nitrofurantoin; Novobiocin; Ophthalmology; Oxytetracycline; Pentobarbital; Polymyxins; Pseudomonas Infections; Quinine; Retina; Sepsis; Streptomycin; Toxicology

Topics: Bacteriophage Typing; Biomedical Research; Carrier State; Child; Chlortetracycline; Drug Resistance; Drug Resistance, Microbial; Humans; Infant; Meningitis; Mice; Oxytetracycline; Penicillins; Pneumonia; Pneumothorax; Sepsis; Staphylococcal Infections; Staphylococcus; Staphylococcus Phages; Streptomycin; Virulence

Topics: Adolescent; Chloramphenicol; Cysts; Echinococcosis; Echinococcosis, Hepatic; Fever; Jaundice; Liver; Oxytetracycline; Pain; Penicillins; Postoperative Complications; Rifamycins; Sepsis; Streptomycin; Suppuration; Surgical Procedures, Operative

Topics: Anti-Bacterial Agents; Bacteriological Techniques; Cerebrospinal Fluid; Chloramphenicol; Colistin; Coma; Diagnosis; Epidemiology; Erythromycin; Listeria; Listeria monocytogenes; Meningitis; Meningitis, Listeria; Novobiocin; Oleandomycin; Oxytetracycline; Penicillins; Seizures; Sepsis; Serologic Tests; Spiramycin; Sulfonamides; Tetracycline

Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Child; Chlortetracycline; Cross Infection; Humans; Infant; Leukocyte Count; Neomycin; Oxytetracycline; Penicillins; Polymyxins; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Staphylococcal Infections; Statistics as Topic; Streptomycin

Topics: Abscess; Arthritis; Child; Chloramphenicol; Diagnosis, Differential; Drainage; Erythromycin; Humans; Infant; Joint Diseases; Novobiocin; Osteomyelitis; Oxytetracycline; Penicillins; Sepsis; Staphylococcal Infections; Streptococcal Infections; Suppuration; Surgical Procedures, Operative; Tetracycline

Topics: Candida albicans; Candidiasis; Colistin; Humans; Infections; Klebsiella; Oxytetracycline; Sepsis; Streptomycin

Topics: Abortion, Induced; Anti-Bacterial Agents; Central Nervous System Stimulants; Communicable Diseases; Diuretics; Female; Humans; Hysterectomy; Injections, Intravenous; Norepinephrine; Obstetrics; Oxytetracycline; Pathology; Povidone; Pregnancy; Pregnancy Complications, Infectious; Puerperal Infection; Sepsis; Shock, Septic; Spironolactone; Urinary Tract Infections

Topics: Bacteriology; Child; Chloramphenicol; Drainage; Empyema; Epidemiology; Erythromycin; Humans; Infant; Lung Abscess; Lung Diseases; Oxytetracycline; Pathology; Penicillins; Pleural Effusion; Pneumonia; Sepsis; Staphylococcal Infections; Streptomycin; Toxicology

Topics: Animals; Bacteremia; Mice; Neomycin; Oxytetracycline; Radiation; Radiation, Ionizing; Sepsis; Streptomycin

Topics: Anti-Bacterial Agents; Bacteremia; Humans; Oxytetracycline; Sepsis; Surgery, Oral; Tooth Extraction

Topics: Bacteremia; Bacteriology; Erythromycin; Humans; Meningitis; Oxytetracycline; Sepsis; Staphylococcal Infections

Topics: Bacteremia; Bacteriology; Humans; Oxytetracycline; Proteus; Proteus Infections; Sepsis; Streptomycin

Topics: Oxytetracycline; Sepsis; Urinary Tract