Compounds > prolyl-phenylalanyl-n-heptylargininamide
Page last updated: 2024-12-07

prolyl-phenylalanyl-n-heptylargininamide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

prolyl-phenylalanyl-N-heptylargininamide: RN given refers to (D-Pro-L-Phe-L-Arg)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID133194
MeSH IDM0122778

Synonyms (8)

Synonym
s-2441 ,
pro-phe-n-heptyl-arg-nh2
l-argininamide, d-prolyl-l-phenylalanyl-n-heptyl-
79358-73-9
(2r)-n-[(2s)-1-[[(2s)-5-(diaminomethylideneamino)-2-(heptylamino)pentanoyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
prolyl-phenylalanyl-n-heptylargininamide
n-(1-{[5-carbamimidamido-2-(heptylamino)-1-hydroxypentylidene]amino}-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboximidic acid
DTXSID101000424
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.50 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
tiopronin
Tiopronin: Sulfhydryl acylated derivative of GLYCINE.		1.9610N-acyl-amino acid
tranexamic acid
Tranexamic Acid: Antifibrinolytic hemostatic used in severe hemorrhage.		1.9610amino acid
fibrinogen
Fibrinogen: Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.. D-iditol : The D-enantiomer of iditol.		1.9610iditolfungal metabolite
bradykinin
[no description available]		1.9610oligopeptidehuman blood serum metabolite;
vasodilator agent
fibrinopeptide a
Fibrinopeptide A: Two small peptide chains removed from the N-terminal segment of the alpha chains of fibrinogen by the action of thrombin during the blood coagulation process. Each peptide chain contains 18 amino acid residues. In vivo, fibrinopeptide A is used as a marker to determine the rate of conversion of fibrinogen to fibrin by thrombin.		1.9610
ConditionIndicatedRelationship StrengthStudiesTrials
Coagulation Disorders, Blood
[description not available]		01.9610
Acute Edematous Pancreatitis
[description not available]		02.3720
Acute Disease
Disease having a short and relatively severe course.		02.3720
Blood Coagulation Disorders
Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions.		01.9610
Pancreatitis
INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.		02.3720
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		01.9610
Dehiscence, Surgical Wound
[description not available]		01.9610
Endotoxin Shock
[description not available]		01.9710
Shock, Septic
Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.		01.9710
Blood Poisoning
[description not available]		01.9610
E coli Infections
[description not available]		01.9610
Escherichia coli Infections
Infections with bacteria of the species ESCHERICHIA COLI.		01.9610
Necrosis
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.		01.9610
Sepsis
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.		01.9610