Compounds > bay i 7433
Page last updated: 2024-09-23

bay i 7433

Description

copovithane: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID71487
MeSH IDM0115059

Synonyms (8)

Synonym
bay-i-7433
copovithane
copovithane [ban]
68045-74-9
unii-3hbm8v07b2
bay i 7433
3hbm8v07b2 ,
1-ethenylpyrrolidin-2-one;2-(methylcarbamoyloxymethyl)prop-2-enyl n-methylcarbamate

Research Excerpts

Overview

ExcerptReference
"Bay i 7433 (Copovithane) is a biological response modifier with antitumour activity in vivo, but no cytotoxic or cytostatic effect in vitro. "( Danova, M; Faravelli, M; Girino, M; Riccardi, A; Salvini, P; Ucci, G, 1986)

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (25.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (75.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
trinitrobenzenesulfonic acid[no description available]medium10arenesulfonic acid;
C-nitro compound		epitope;
explosive;
reagent
n-vinyl-2-pyrrolidinone[no description available]medium82pyrrolidin-2-ones
carbamates[no description available]medium82amino-acid anion
gentamicin[no description available]medium10
netilmicin[no description available]medium10
clindamycin[no description available]medium10
ConditionIndicatedRelationship StrengthStudiesTrials
Benign Neoplasms0medium31
Blood Poisoning0low10
Bloodstream Infection0low10
Cancer0medium31
Cancer of Colon0medium11
Cancer of Rectum0medium11
Cancer of the Colon0medium11
Cancer of the Rectum0medium11
Carcinoma0medium11
Carcinoma, Anaplastic0medium11
Carcinoma, Spindle-Cell0medium11
Carcinoma, Undifferentiated0medium11
Carcinomatosis0medium11
Colon Cancer0medium11
Colon Neoplasms0medium11
Colonic Cancer0medium11
Colonic Neoplasms0medium11
Disease Models, Animal0low10
Epithelial Neoplasms, Malignant0medium11
Epithelial Tumors, Malignant0medium11
Epithelioma0medium11
Infection, Postoperative Wound0low10
Infection, Surgical Wound0low10
Infections, Klebsiella0low10
Kaposi Sarcoma0low10
Kaposi's Sarcoma0low10
Klebsiella Infections0low10
Leiomyosarcoma0low10
Leiomyosarcoma, Epithelioid0low10
Leiomyosarcoma, Myxoid0low10
Malignancy0medium31
Malignant Epithelial Neoplasms0medium11
Malignant Melanoma0low20
Malignant Neoplasms0medium31
Melanoma0low20
Multiple Idiopathic Pigmented Hemangiosarcoma0low10
Neoplasia0medium31
Neoplasm0medium31
Neoplasms0medium31
Neoplasms, Benign0medium31
Neoplasms, Colonic0medium11
Neoplasms, Malignant Epithelial0medium11
Neoplasms, Rectal0medium11
Peritonitis0low20
Poisoning, Blood0low10
Postoperative Wound Infection0low10
Primary Peritonitis0low20
Pyaemia0low10
Pyemia0low10
Pyohemia0low10
Rectal Cancer0medium11
Rectal Neoplasms0medium11
Rectal Tumors0medium11
Rectum Cancer0medium11
Rectum Neoplasms0medium11
Sarcoma, Kaposi0low10
Secondary Peritonitis0low20
Sepsis0low10
Septicemia0low10
Severe Sepsis0low10
Surgical Site Infection0low10
Surgical Wound Infection0low10
Tumors0medium31
Wound Infection, Postoperative0low10
Wound Infection, Surgical0low10

Research Highlights

Pharmacokinetics (1)

ArticleYear
Pharmacokinetics and tissue disposition of the biological response modifier BAY i 7433 (copovithane) in patients with cancer.
Cancer chemotherapy and pharmacology, Volume: 18, Issue: 3		1986
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (1)

ArticleYear
Reversal of cyclosporine-induced mortality with a synthetic polymeric immunostimulant in a murine model of fecal peritonitis.
Transplantation, Volume: 39, Issue: 4		1985
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]