pyrazines has been researched along with Sepsis in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al Zoubi, S; Chiazza, F; Coldewey, SM; Collino, M; Collotta, D; Martin, L; O'Riordan, CE; Purvis, GSD; Stiehler, L; Thiemermann, C; Wissuwa, B | 1 |
| Chen, Y; Han, Y; Qian, X; Wu, J; Yang, Q; Ying, J; Zhang, Y; Zhu, H | 1 |
| Callender, LA; Coldewey, SM; Collino, M; Collotta, D; Ferreira Alves, G; Greaves, DR; Krieg, N; Mohammad, S; O'Riordan, CE; Purvis, GSD; Sheikh, MH; Thiemermann, C; Wissuwa, B | 1 |
| Jang, J; Jho, EH; Kwon, YV; Lee, H; Sim, I; Song, J; Yoon, Y | 1 |
| Liu, K; Liu, W; Shan, L; Tang, J; Zhang, S | 1 |
| Chen, YG; Huang, LL; Liu, B; Tao, XG; Wang, JQ; Wei, L; Zhang, L | 1 |
| Ahn, YS; Han, SH; Jeong, SJ; Kim, JM; Kim, JS; Shin, JS; Woo, JH | 1 |
| Chen, Y; Gao, C; Li, C; Li, W; Peng, H; Wang, H; Zhang, X | 1 |
| Callahan, LA; Supinski, GS; Vanags, J | 1 |
| Bredenoord, AJ; De Man, JG; De Schepper, HU; De Winter, BY; Pelckmans, PA; Timmermans, JP; Van Nassauw, L | 1 |
| Chen, QF; Guo, LH; Hu, YN; Wang, L; Yang, C; Zhang, MZ | 1 |
| Colucci, J; Coulombe, N; Han, Y; Huang, J; Méthot, N; Nicholson, DW; Rasper, D; Roy, S; Tam, J; Toulmond, S; Vaillancourt, JP; Xanthoudakis, S; Zamboni, R | 1 |
| Ahsan, MH; Purchio, AF; West, DB; Zhang, N | 1 |
| Binder, D; Georgopoulos, A; Noe, CR; Nussbaumer, J; Prager, BC; Turnowsky, F | 1 |
| Mingrino, F; Ortali, V; Tosti, U | 1 |
15 other study(ies) available for pyrazines and Sepsis
| Article | Year |
|---|---|
Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Benzamides; Cecum; Disease Models, Animal; Heart; Heart Diseases; Inflammasomes; Ligation; Male; Mice; Mice, Inbred C57BL; Piperidines; Protein Kinase Inhibitors; Punctures; Pyrazines; Pyrazoles; Pyrimidines; Sepsis | 2019 |
Ligustrazine suppresses renal NMDAR1 and caspase-3 expressions in a mouse model of sepsis-associated acute kidney injury.
Topics: Acute Kidney Injury; Animals; Caspase 3; Disease Models, Animal; Gene Expression Regulation; Male; Mice; Pyrazines; Receptors, N-Methyl-D-Aspartate; Sepsis | 2020 |
X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Benzamides; Disease Models, Animal; Inflammasomes; Macrophages; Male; Mice; Mice, Inbred CBA; Multiple Organ Failure; Phagocytosis; Piperidines; Protein Kinase Inhibitors; Pyrazines; Sepsis; X-Linked Combined Immunodeficiency Diseases | 2020 |
LGK974 suppresses lipopolysaccharide-induced endotoxemia in mice by modulating the crosstalk between the Wnt/β-catenin and NF-κB pathways.
Topics: Animals; beta Catenin; Endotoxemia; Enzyme Inhibitors; Gene Expression Regulation; Humans; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Pyrazines; Pyridines; Sepsis; Wnt1 Protein | 2021 |
Tetramethylpyrazine Showed Therapeutic Effects on Sepsis-Induced Acute Lung Injury in Rats by Inhibiting Endoplasmic Reticulum Stress Protein Kinase RNA-Like Endoplasmic Reticulum Kinase (PERK) Signaling-Induced Apoptosis of Pulmonary Microvascular Endoth
Topics: Acute Lung Injury; Animals; Apoptosis; Cell Separation; eIF-2 Kinase; Endoplasmic Reticulum Stress; Endothelial Cells; Kaplan-Meier Estimate; Lung; Microvessels; Oxygen; Pyrazines; Rats, Sprague-Dawley; Respiratory Function Tests; Sepsis; Signal Transduction; Survival Analysis | 2018 |
Tetramethylpyrazine upregulates the aquaporin 8 expression of hepatocellular mitochondria in septic rats.
Topics: Animals; Aquaporins; Calcium Channel Blockers; Disease Models, Animal; Hepatocytes; Liver Diseases; Male; Mitochondria, Liver; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sepsis; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
The effect of bortezomib on expression of inflammatory cytokines and survival in a murine sepsis model induced by cecal ligation and puncture.
Topics: Animals; Boronic Acids; Bortezomib; Cecum; Cell Adhesion Molecules; Cell Line; Cell Proliferation; Cell Survival; Chymotrypsin; Cytokines; Disease Models, Animal; Inflammation Mediators; Ligation; Lipopolysaccharides; Lung; Male; Mice, Inbred C57BL; Nitric Oxide; Proteasome Inhibitors; Punctures; Pyrazines; Sepsis | 2015 |
Ligustrazine effect on lipopolysaccharide-induced pulmonary damage in rats.
Topics: Animals; Blood Gas Analysis; Cell-Derived Microparticles; Disease Models, Animal; Endothelial Cells; Injections, Intraperitoneal; Lipopolysaccharides; Lung; Lung Injury; Male; Oxygen; Partial Pressure; Platelet Endothelial Cell Adhesion Molecule-1; Pyrazines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Sepsis; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2015 |
Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction.
Topics: Animals; Atrophy; Boronic Acids; Bortezomib; Caspase 3; Cysteine Proteinase Inhibitors; Diaphragm; Endotoxemia; Enzyme Activation; Leupeptins; Male; Muscle Contraction; Muscle Weakness; Oligopeptides; Organ Size; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Rats; Rats, Sprague-Dawley; Sepsis; Tyrosine | 2009 |
Involvement of afferent neurons in the pathogenesis of endotoxin-induced ileus in mice: role of CGRP and TRPV1 receptors.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Gastric Emptying; Gastrointestinal Transit; Hexamethonium; Ileus; Lipopolysaccharides; Male; Mice; Neurons, Afferent; Peptide Fragments; Pyrazines; Pyridines; Receptors, Calcitonin Gene-Related Peptide; Sepsis; TRPV Cation Channels | 2009 |
Effects of tetramethylpyrazine on cardiac function and mortality rate in septic rats.
Topics: Animals; Heart Function Tests; Male; Myocardium; Pyrazines; Rats; Rats, Sprague-Dawley; Sepsis; Stroke Volume; Survival Analysis; Tumor Necrosis Factor-alpha; Ultrasonography | 2012 |
Differential efficacy of caspase inhibitors on apoptosis markers during sepsis in rats and implication for fractional inhibition requirements for therapeutics.
Topics: Animals; Apoptosis; Biomarkers; Caspase 3; Caspase Inhibitors; Cysteine Proteinase Inhibitors; DNA Fragmentation; Female; Genes, bcl-2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxadiazoles; Pyrazines; Rats; Rats, Sprague-Dawley; Sepsis; Spectrin; T-Lymphocytes | 2004 |
Serum amyloid A-luciferase transgenic mice: response to sepsis, acute arthritis, and contact hypersensitivity and the effects of proteasome inhibition.
Topics: Acute Disease; Animals; Arthritis, Experimental; Boronic Acids; Bortezomib; Dermatitis, Contact; Disease Models, Animal; Enzyme Induction; Female; Genetic Vectors; Lipopolysaccharides; Luciferases; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Organ Specificity; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Sepsis; Serum Amyloid A Protein; Tumor Necrosis Factor-alpha | 2005 |
[Pyrazine-1,4-dioxides fused to heterocycles / 2nd comm.: Synthesis and antibacterial activity of substituted pyrido[2,3-b]pyrazine-1,4-dioxides (author's transl)].
Topics: Animals; Anti-Bacterial Agents; Bacteria; Female; Mice; Microbial Sensitivity Tests; Pyelonephritis; Pyrazines; Sepsis | 1982 |
[Current data on meningococcal infections].
Topics: Humans; Italy; Meningitis; Meningitis, Meningococcal; Meningococcal Infections; Pyrazines; Sepsis; Sulfadiazine; Sulfanilamides; Sulfonamides | 1971 |