sodium-hypochlorite and Sepsis

The article presents an analysis of surgical treatment of 2155 patients with incarcerated hernias of the anterior abdominal wall. Pyo-septic complications took place in 24.3%. A comparison of results of treatment by traditional methods with those using solution of sodium hypochlorite (indirect electrochemical oxidation of blood) has shown that in the group of patient treated with sodium hypochlorite lethality was reduced from (18.8 +/- 0.2)% to (11.2 +/- 0.2)%, the amount of suppuration of the operative wound was 1.8 times less and the average number of bed-days was (4.5 +/- 0.2) less.

Topics: Disinfectants; Female; Hernia; Herniorrhaphy; Humans; Infant, Newborn; Infusions, Intravenous; Male; Peritonitis; Postoperative Care; Postoperative Complications; Recurrence; Sepsis; Sodium Hypochlorite; Solutions; Time Factors

The authors present a series of 6 deaths due to the uncommon cause of chemical burns. Of the 6 deaths due to chemical burns, 4 deaths were due to ingestion of a chemical, 1 death was caused by chemical burns of the skin, and 1 death resulted from rectal insufflation of a chemical. Seven additional cases where chemical burns may have been a contributing factor to the death or an incidental finding are also presented. Four cases are related to an incident involving chemical exposure during an industrial explosion. Three cases involve motor fuel burns of the skin. Two cases concern a plane crash incident, and 1 case involved a vehicular collision. Cases are derived from the records of the Dallas County Medical Examiner's Office and those of the authors' consultation practices. Each of the cases is presented, followed by a discussion of the various mechanisms of chemical injury.

Topics: Accidents; Administration, Inhalation; Administration, Rectal; Adult; Burns, Chemical; Caustics; Disinfectants; Explosions; Female; Fibrosis; Forensic Pathology; Gastrointestinal Tract; Humans; Infant; Lye; Male; Mercuric Chloride; Middle Aged; Phosphoric Acids; Respiratory Aspiration; Respiratory System; Sepsis; Sodium Hypochlorite; Suicide

A method devised by the authors of renovation of capillary dialyzers, after rinsing the blood and the liquid systems of the dialyzers is discussed. After rising the blood and the liquid systems of the dialyzers by water at 2 atm.--water being conditioned by the apparatus for reverse osmosis--in the liquid system overpressure of 2 atm was produced by water, the by 0.5% solution of sodium hypochlorite. After 2-3 minutes sodium hypochlorite was rinsed out and both systems were filled in by 1-2% formaldehyde solution. Immediately before using the dialyzer in the same patient the fluid system was rinsed with conditioned water, and the blood system with 21 of sterile distilled water and with 41 of 0.9% NaCl solution. In order to facilitate the renovation process a semi-automatic apparatus was designed, which makes it possible to renovate two dialyzers at once. This method makes it possible to use 80% capillary dialyzers four times with lateral input of the blood system, and four times 100% ones with central input. Experiments on animals and clinical observations and bacteriological studies shoved that the renovation process was atoxic, apyrogenic and sterile. No damage of capillaries and no reactions in subsequent use in patients under dialysis were observed.

Topics: Animals; Bacterial Infections; Cellulose; Equipment Contamination; Equipment Safety; Formaldehyde; Humans; Hydrostatic Pressure; Kidneys, Artificial; Mice; Rabbits; Sepsis; Sodium Hypochlorite; Sterilization