n(g),n(g')-dimethyl-l-arginine has been researched along with Sepsis in 9 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "L-arginine and ADMA levels were higher in neonates with sepsis compared to controls (p = 0." | 9.20 | Asymmetric dimethylarginine and L-arginine levels in neonatal sepsis and septic shock. ( Aydemir, O; Bas, AY; Demirel, N; Ozcan, B; Yucel, H, 2015) |
| "As modulators of nitric oxide generation, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) may play important roles in sepsis." | 8.02 | Evaluation of Biomarkers in Sepsis: High Dimethylarginine (ADMA and SDMA) Concentrations Are Associated with Mortality. ( Lynch, KL; van Wijk, XMR; Yun, C, 2021) |
| "Increased plasma concentrations of the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine, decreased arginine bioavailability, and mitochondrial dysfunction have been reported in adult sepsis." | 7.78 | Evaluation of asymmetric dimethylarginine, arginine, and carnitine metabolism in pediatric sepsis. ( Chace, DH; De Jesus, VR; Haymond, S; Ralay Ranaivo, H; Wainwright, MS; Wang, D; Weiss, SL, 2012) |
| "Impaired endothelial and microvascular function due to decreased endothelial NO bioavailability is a potential mechanism linking increased plasma ADMA with organ failure and death in sepsis." | 5.37 | Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis. ( Anstey, NM; Celermajer, DS; Darcy, CJ; Davis, JS; Jones, C; McNeil, YR; Stephens, DP; Yeo, TW, 2011) |
| " In recent years, the emerging new understanding of the NO pathway has shown that an endogenously produced inhibitor of NOS, asymmetric dimethylarginine (ADMA), a host response to infection, may play an important role in the pathophysiology of sepsis as well as organ damage during ischemia-reperfusion." | 5.22 | A new perspective on NO pathway in sepsis and ADMA lowering as a potential therapeutic approach. ( Kellum, JA; Lee, Y; Singh, J, 2022) |
| "L-arginine and ADMA levels were higher in neonates with sepsis compared to controls (p = 0." | 5.20 | Asymmetric dimethylarginine and L-arginine levels in neonatal sepsis and septic shock. ( Aydemir, O; Bas, AY; Demirel, N; Ozcan, B; Yucel, H, 2015) |
| "As modulators of nitric oxide generation, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) may play important roles in sepsis." | 4.02 | Evaluation of Biomarkers in Sepsis: High Dimethylarginine (ADMA and SDMA) Concentrations Are Associated with Mortality. ( Lynch, KL; van Wijk, XMR; Yun, C, 2021) |
| "Serum concentrations of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, may contribute to endothelial dysfunction and organ failure in sepsis." | 3.79 | Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients. ( Bruensing, J; Buendgens, L; Dückers, H; Koch, A; Kunze, J; Luedde, T; Matthes, M; Tacke, F; Trautwein, C; Weiskirchen, R, 2013) |
| "Increased plasma concentrations of the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine, decreased arginine bioavailability, and mitochondrial dysfunction have been reported in adult sepsis." | 3.78 | Evaluation of asymmetric dimethylarginine, arginine, and carnitine metabolism in pediatric sepsis. ( Chace, DH; De Jesus, VR; Haymond, S; Ralay Ranaivo, H; Wainwright, MS; Wang, D; Weiss, SL, 2012) |
| "Dysfunctions of the L-arginine (L-arg)/nitric-oxide (NO) pathway are suspected to be important for the pathogenesis of multiple organ dysfunction syndrome (MODS) in septic shock." | 3.78 | L-arginine and asymmetric dimethylarginine are early predictors for survival in septic patients with acute liver failure. ( Bierhaus, A; Brenner, T; Bruckner, T; Fleming, TH; Hofer, S; Krauser, U; Martin, E; Mieth, M; Nawroth, PP; Rosenhagen, C; Weigand, MA, 2012) |
| "Impaired endothelial and microvascular function due to decreased endothelial NO bioavailability is a potential mechanism linking increased plasma ADMA with organ failure and death in sepsis." | 1.37 | Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis. ( Anstey, NM; Celermajer, DS; Darcy, CJ; Davis, JS; Jones, C; McNeil, YR; Stephens, DP; Yeo, TW, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, J | 1 |
| Lee, Y | 1 |
| Kellum, JA | 1 |
| van Wijk, XMR | 1 |
| Yun, C | 1 |
| Lynch, KL | 1 |
| Koch, A | 1 |
| Weiskirchen, R | 1 |
| Kunze, J | 1 |
| Dückers, H | 1 |
| Bruensing, J | 1 |
| Buendgens, L | 1 |
| Matthes, M | 1 |
| Luedde, T | 1 |
| Trautwein, C | 1 |
| Tacke, F | 1 |
| Aydemir, O | 1 |
| Ozcan, B | 1 |
| Yucel, H | 1 |
| Bas, AY | 1 |
| Demirel, N | 1 |
| Dounousi, E | 1 |
| Torino, C | 1 |
| Pizzini, P | 1 |
| Cutrupi, S | 1 |
| Panuccio, V | 1 |
| D'Arrigo, G | 1 |
| Abd ElHafeez, S | 1 |
| Tripepi, G | 1 |
| Mallamaci, F | 1 |
| Zoccali, C | 1 |
| Mortensen, KM | 1 |
| Itenov, TS | 1 |
| Haase, N | 1 |
| Müller, RB | 1 |
| Ostrowski, SR | 1 |
| Johansson, PI | 1 |
| Olsen, NV | 1 |
| Perner, A | 1 |
| Søe-Jensen, P | 1 |
| Bestle, MH | 1 |
| Davis, JS | 1 |
| Darcy, CJ | 1 |
| Yeo, TW | 1 |
| Jones, C | 1 |
| McNeil, YR | 1 |
| Stephens, DP | 1 |
| Celermajer, DS | 1 |
| Anstey, NM | 1 |
| Weiss, SL | 1 |
| Haymond, S | 1 |
| Ralay Ranaivo, H | 1 |
| Wang, D | 1 |
| De Jesus, VR | 1 |
| Chace, DH | 1 |
| Wainwright, MS | 1 |
| Brenner, T | 1 |
| Fleming, TH | 1 |
| Rosenhagen, C | 1 |
| Krauser, U | 1 |
| Mieth, M | 1 |
| Bruckner, T | 1 |
| Martin, E | 1 |
| Nawroth, PP | 1 |
| Weigand, MA | 1 |
| Bierhaus, A | 1 |
| Hofer, S | 1 |
1 review available for n(g),n(g')-dimethyl-l-arginine and Sepsis
| Article | Year |
|---|---|
A new perspective on NO pathway in sepsis and ADMA lowering as a potential therapeutic approach.
Topics: Animals; Arginine; Humans; Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Sepsis | 2022 |
1 trial available for n(g),n(g')-dimethyl-l-arginine and Sepsis
| Article | Year |
|---|---|
Asymmetric dimethylarginine and L-arginine levels in neonatal sepsis and septic shock.
Topics: Arginine; Biomarkers; Case-Control Studies; Female; Humans; Infant, Newborn; Male; Multiple Organ Fa | 2015 |
7 other studies available for n(g),n(g')-dimethyl-l-arginine and Sepsis
| Article | Year |
|---|---|
Evaluation of Biomarkers in Sepsis: High Dimethylarginine (ADMA and SDMA) Concentrations Are Associated with Mortality.
Topics: Arginine; Biomarkers; Humans; Sepsis | 2021 |
Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Case-Control Studies; Critical Ill | 2013 |
Effect of inflammation by acute sepsis on intact fibroblast growth factor 23 (iFGF23) and asymmetric dimethyl arginine (ADMA) in CKD patients.
Topics: Arginine; Biomarkers; Case-Control Studies; Female; Fibroblast Growth Factor-23; Fibroblast Growth F | 2016 |
High Levels of Methylarginines Were Associated With Increased Mortality in Patients With Severe Sepsis.
Topics: Aged; Arginine; Female; Humans; Male; Middle Aged; Nitric Oxide; Proportional Hazards Models; Sepsis | 2016 |
Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis.
Topics: Adult; Aged; Arginine; Biological Availability; Case-Control Studies; Endothelium, Vascular; Female; | 2011 |
Evaluation of asymmetric dimethylarginine, arginine, and carnitine metabolism in pediatric sepsis.
Topics: Adolescent; Arginine; Carnitine; Case-Control Studies; Child; Child, Preschool; Enzyme-Linked Immuno | 2012 |
L-arginine and asymmetric dimethylarginine are early predictors for survival in septic patients with acute liver failure.
Topics: Aged; Arginine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Liver Failure, Acute; Male; Middl | 2012 |