creatine and Sepsis
creatine has been researched along with Sepsis in 20 studies
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to explore the effect and mechanisms of rhein on sepsis-induced acute kidney injury by injecting lipopolysaccharide (LPS) and cecal ligation and puncture (CLP) in vivo, and on LPS-induced HK-2 cells in vitro." | 7.81 | Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities. ( Fan, HY; Li, P; Qi, D; Sun, JF; Yu, C, 2015) |
| "During sepsis, an increase in myocellular free Cr levels is associated with enhanced tyrosine phosphorylation of the CreaT, which is likely induced by active c-Src." | 7.71 | Complement regulatory protein CD59 involves c-SRC related tyrosine phosphorylation of the creatine transporter in skeletal muscle during sepsis. ( Jacobs, DO; Shang, LH; Wang, W, 2002) |
| "Pretreatment with mifepristone reduces the demand for adenosine triphosphate production from phosphocreatine breakdown and downregulates Na(+)-K+ adenosine triphosphatase activity during sepsis." | 7.69 | Glucocorticoid receptor antagonism by mifepristone alters phosphocreatine breakdown during sepsis. ( Jacobs, DO; Mitsuo, T; Prechek, D; Rounds, J; Wilmore, DW, 1996) |
| "Gentamicin is a common antibiotic used to treat sepsis in neonates." | 3.83 | Should gentamicin trough levels be routinely obtained in term neonates? ( El-Chaar, G; Hanna, N; Ibrahim, J; Islam, S; Maffei, D; Nayak, A; Ponnaiya, S; Rosenfeld, W, 2016) |
| "This study aimed to explore the effect and mechanisms of rhein on sepsis-induced acute kidney injury by injecting lipopolysaccharide (LPS) and cecal ligation and puncture (CLP) in vivo, and on LPS-induced HK-2 cells in vitro." | 3.81 | Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities. ( Fan, HY; Li, P; Qi, D; Sun, JF; Yu, C, 2015) |
| "During sepsis, an increase in myocellular free Cr levels is associated with enhanced tyrosine phosphorylation of the CreaT, which is likely induced by active c-Src." | 3.71 | Complement regulatory protein CD59 involves c-SRC related tyrosine phosphorylation of the creatine transporter in skeletal muscle during sepsis. ( Jacobs, DO; Shang, LH; Wang, W, 2002) |
| "Pretreatment with mifepristone reduces the demand for adenosine triphosphate production from phosphocreatine breakdown and downregulates Na(+)-K+ adenosine triphosphatase activity during sepsis." | 3.69 | Glucocorticoid receptor antagonism by mifepristone alters phosphocreatine breakdown during sepsis. ( Jacobs, DO; Mitsuo, T; Prechek, D; Rounds, J; Wilmore, DW, 1996) |
| "Sepsis was defined clinically." | 2.75 | Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit. ( Endre, ZH; Frampton, CM; Nejat, M; Pickering, JW; Shaw, GM; Walker, RJ; Westhuyzen, J, 2010) |
| "The use of a computer-based consultation program to customize dosage regimens of antimicrobials for patients with meningitis or bacteremia is described." | 1.26 | Computer-assisted customized antimicrobial dosages. ( Bennett, SW; Scott, AC, 1980) |
Research
Studies (20)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 7 (35.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Chang, HH | 1 |
| Wu, CL | 1 |
| Tsai, CC | 1 |
| Chiu, PF | 1 |
| Li, N | 1 |
| Hu, DH | 1 |
| Wang, YJ | 1 |
| Hu, XL | 1 |
| Zhang, Y | 1 |
| Li, XQ | 1 |
| Shi, JH | 1 |
| Bai, XZ | 1 |
| Cai, WX | 1 |
| Li, P | 2 |
| Bledsoe, G | 1 |
| Yang, ZR | 1 |
| Fan, H | 1 |
| Chao, L | 1 |
| Chao, J | 1 |
| Khowailed, A | 1 |
| Younan, SM | 1 |
| Ashour, H | 1 |
| Kamel, AE | 1 |
| Sharawy, N | 1 |
| Yu, C | 1 |
| Qi, D | 1 |
| Sun, JF | 1 |
| Fan, HY | 1 |
| Hanada, S | 1 |
| Iwata, S | 1 |
| Kishi, K | 1 |
| Morozumi, M | 1 |
| Chiba, N | 1 |
| Wajima, T | 1 |
| Takata, M | 1 |
| Ubukata, K | 1 |
| Ibrahim, J | 1 |
| Maffei, D | 1 |
| El-Chaar, G | 1 |
| Islam, S | 1 |
| Ponnaiya, S | 1 |
| Nayak, A | 1 |
| Rosenfeld, W | 1 |
| Hanna, N | 1 |
| Doi, K | 1 |
| Leelahavanichkul, A | 1 |
| Hu, X | 1 |
| Sidransky, KL | 1 |
| Zhou, H | 1 |
| Qin, Y | 1 |
| Eisner, C | 1 |
| Schnermann, J | 1 |
| Yuen, PS | 1 |
| Star, RA | 1 |
| Mikkelsen, MM | 1 |
| Andersen, NH | 1 |
| Christensen, TD | 1 |
| Hansen, TK | 1 |
| Eiskjaer, H | 1 |
| Mogensen, CE | 1 |
| Hjortdal, VE | 1 |
| Johnsen, SP | 1 |
| Nejat, M | 1 |
| Pickering, JW | 1 |
| Walker, RJ | 1 |
| Westhuyzen, J | 1 |
| Shaw, GM | 1 |
| Frampton, CM | 1 |
| Endre, ZH | 1 |
| Wang, W | 2 |
| Shang, LH | 2 |
| Jacobs, DO | 3 |
| Phu, NH | 1 |
| Hien, TT | 1 |
| Mai, NT | 1 |
| Chau, TT | 1 |
| Chuong, LV | 1 |
| Loc, PP | 1 |
| Winearls, C | 1 |
| Farrar, J | 1 |
| White, N | 1 |
| Day, N | 1 |
| LOVETT, VF | 1 |
| YAMAUCHI, H | 1 |
| PHILLIPPI, PJ | 1 |
| PRESWICK, G | 1 |
| JEREMY, D | 1 |
| Guadalupe Vásquez-Mendoza, M | 1 |
| Vargas-Origel, A | 1 |
| Del Carmen Ramos-Jiménez, A | 1 |
| Aguilar-Orozco, G | 1 |
| Romero-Gutiérrez, G | 1 |
| Strauch, M | 1 |
| McLaughlin, JS | 1 |
| Mansberger, A | 1 |
| Young, J | 1 |
| Mendonca, P | 1 |
| Gray, K | 1 |
| Cowley, RA | 1 |
| Bennett, SW | 1 |
| Scott, AC | 1 |
| Mitsuo, T | 1 |
| Rounds, J | 1 |
| Prechek, D | 1 |
| Wilmore, DW | 1 |
| Mayser, P | 1 |
| Imkampe, A | 1 |
| Winkeler, M | 1 |
| Papavassilis, C | 1 |
| Jobst, MA | 1 |
| Bell, B | 1 |
| Zhao, CR | 1 |
Trials
3 trials available for creatine and Sepsis
| Article | Year |
|---|---|
Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Area Under Curve; Australia; Creatine; Critical | 2010 |
Hemofiltration and peritoneal dialysis in infection-associated acute renal failure in Vietnam.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Adult; Aged; Bacterial Infections; Cost-Benefit Analysis; | 2002 |
Efficacy and renal toxicity of one daily dose of amikacin versus conventional dosage regime.
Topics: Amikacin; Anti-Bacterial Agents; beta 2-Microglobulin; Creatine; Double-Blind Method; Glomerular Fil | 2007 |
Other Studies
17 other studies available for creatine and Sepsis
| Article | Year |
|---|---|
Association between predialysis creatinine and mortality in acute kidney injury patients requiring dialysis.
Topics: Acute Kidney Injury; Albumins; Creatine; Creatinine; Humans; Intensive Care Units; Prognosis; Renal | 2022 |
[Effects of adipose-derived stem cells on renal injury in burn mice with sepsis].
Topics: Adipose Tissue; Animals; Burns; Creatine; Cyclooxygenase 2; Disease Models, Animal; Interleukin-10; | 2013 |
Human kallistatin administration reduces organ injury and improves survival in a mouse model of polymicrobial sepsis.
Topics: Animals; Apoptosis; Blood Urea Nitrogen; Caspase 3; Creatine; Disease Models, Animal; HMGB1 Protein; | 2014 |
Effects of ghrelin on sepsis-induced acute kidney injury: one step forward.
Topics: Acute Kidney Injury; Animals; Arterial Pressure; Blood Urea Nitrogen; Cecum; Creatine; Disease Model | 2015 |
Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities.
Topics: Acute Kidney Injury; Animals; Anthraquinones; Blood Urea Nitrogen; Cell Line; Creatine; Disease Mode | 2015 |
Host Factors and Biomarkers Associated with Poor Outcomes in Adults with Invasive Pneumococcal Disease.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Creatine; Female; Humans; Japan; Kaplan-Mei | 2016 |
Should gentamicin trough levels be routinely obtained in term neonates?
Topics: Academic Performance; Anti-Bacterial Agents; Creatine; Drug Monitoring; Female; Gentamicins; Humans; | 2016 |
Pre-existing renal disease promotes sepsis-induced acute kidney injury and worsens outcome.
Topics: Animals; Capillary Permeability; Creatine; Disease Models, Animal; Hemodynamics; Interleukin-10; Kid | 2008 |
Microalbuminuria and short-term prognosis in patients undergoing cardiac surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albumins; Albuminuria; Atrial Fibrillation; Biomarkers; | 2009 |
Complement regulatory protein CD59 involves c-SRC related tyrosine phosphorylation of the creatine transporter in skeletal muscle during sepsis.
Topics: Animals; CD59 Antigens; Creatine; CSK Tyrosine-Protein Kinase; Male; Membrane Transport Proteins; Mu | 2002 |
HEMODIALYSIS IN THE TREATMENT OF POSTOPERATIVE ACUTE RENAL FAILURE ASSOCIATED WITH JAUNDICE: A REPORT OF THREE CASES.
Topics: Acute Kidney Injury; Bilirubin; Biopsy; Cholecystectomy; Creatine; Creatinine; Halothane; Humans; Ja | 1964 |
SUBCLINICAL POLYNEUROPATHY IN RENAL INSUFFICIENCY.
Topics: Blood Chemical Analysis; Blood Urea Nitrogen; Creatine; Creatinine; Diagnosis; Glomerulonephritis; G | 1964 |
Effects of septic shock on renal function in humans.
Topics: Aged; Chlorides; Creatine; Female; Glycosuria; Humans; Kidney; Kidney Function Tests; Male; Middle A | 1967 |
Computer-assisted customized antimicrobial dosages.
Topics: Adult; Anti-Bacterial Agents; Child; Computers; Creatine; Diagnosis, Computer-Assisted; Drug Adminis | 1980 |
Glucocorticoid receptor antagonism by mifepristone alters phosphocreatine breakdown during sepsis.
Topics: Adenosine Triphosphate; Animals; Corticosterone; Creatine; Creatine Kinase; Down-Regulation; Energy | 1996 |
Growth requirements and nitrogen metabolism of Malassezia furfur.
Topics: Allantoin; Amino Acids; Ammonium Chloride; Ammonium Sulfate; Cell Division; Creatine; Creatinine; Cu | 1998 |
Cr supplementation decreases tyrosine phosphorylation of the CreaT in skeletal muscle during sepsis.
Topics: Administration, Oral; Animals; Creatine; Down-Regulation; Enzyme Activation; Male; Membrane Transpor | 2002 |