chlorhexidine-gluconate--lidocaine-drug-combination and Sepsis

To study the disinfecting effect of the lubricant Instillagel for the urethra in children, bacteriologic tests of the urethra were performed immediately before and after cystoscopy in 100 children. In addition urine cultures were taken during and after cystoscopy. The culture of the urethra before cystoscopy was positive in 75 children. For 46 of these children the second culture after cystoscopy plus Instillagel appeared to be sterile while in 20 children a considerable reduction in the number of bacteria was found. Out of 92 children with an initially sterile urine culture, the culture of the urine voided immediately after the cystoscopy appeared to be contaminated in 2 while several weeks later an infected urine was found in 5 children. From this study we may conclude that during cystoscopy Instillagel has a good disinfecting effect for the urethra in children.

Topics: Child; Chlorhexidine; Cross Infection; Cystoscopy; Disinfectants; Drug Combinations; Female; Humans; Lidocaine; Lubrication; Male; Sepsis; Urethra; Urinary Tract Infections