dioctadecylamidoglycylspermine: a lipospermine used to coat DNA to facilitate gene transfer into mammalian primary endocrine cells; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 130091 |
| SCHEMBL ID | 1735875 |
| MeSH ID | M0169577 |
| Synonym |
|---|
| dioctadecylamidoglycylspermine |
| (2s)-2,5-bis(3-aminopropylamino)-n-[2-(dioctadecylamino)acetyl]pentanamide |
| glycinamide, n2,n5-bis(3-aminopropyl)-l-ornithyl-n,n-dioctadecyl- |
| 124050-77-7 |
| 1-dogs |
| SCHEMBL1735875 |
| n-[n~2~,n~5~-bis(3-aminopropyl)ornithyl]-2-(dioctadecylamino)ethanimidic acid |
| DTXSID40924690 |
| Excerpt | Reference |
|---|---|
| "Dioctadecylamidoglycylspermine (DOGS) is a cationic lipid vector capable of efficiently introducing DNA into various eukaryotic cells. " | ( Emi, N; Kanbe, T; Saito, H; Yoshikawa, K; Yoshikawa, Y, 1996) |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (5.26) | 18.7374 |
| 1990's | 29 (76.32) | 18.2507 |
| 2000's | 6 (15.79) | 29.6817 |
| 2010's | 1 (2.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 42 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Article | Year |
|---|---|
| Characterization of liposome-mediated gene delivery: expression, stability and pharmacokinetics of plasmid DNA. Gene therapy, Volume: 4, Issue: 3 | 1997 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |