Page last updated: 2024-12-07

dioctadecylamidoglycylspermine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

dioctadecylamidoglycylspermine: a lipospermine used to coat DNA to facilitate gene transfer into mammalian primary endocrine cells; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID130091
SCHEMBL ID1735875
MeSH IDM0169577

Synonyms (8)

Synonym
dioctadecylamidoglycylspermine
(2s)-2,5-bis(3-aminopropylamino)-n-[2-(dioctadecylamino)acetyl]pentanamide
glycinamide, n2,n5-bis(3-aminopropyl)-l-ornithyl-n,n-dioctadecyl-
124050-77-7
1-dogs
SCHEMBL1735875
n-[n~2~,n~5~-bis(3-aminopropyl)ornithyl]-2-(dioctadecylamino)ethanimidic acid
DTXSID40924690

Research Excerpts

Overview

Dioctadecylamidoglycylspermine (DOGS) is a cationic lipid vector capable of efficiently introducing DNA into various eukaryotic cells.

ExcerptReferenceRelevance
"Dioctadecylamidoglycylspermine (DOGS) is a cationic lipid vector capable of efficiently introducing DNA into various eukaryotic cells. "( Folding and aggregation of DNA chains induced by complexation with lipospermine: formation of a nucleosome-like structure and network assembly.
Emi, N; Kanbe, T; Saito, H; Yoshikawa, K; Yoshikawa, Y, 1996
)
1.74
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (38)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (5.26)18.7374
1990's29 (76.32)18.2507
2000's6 (15.79)29.6817
2010's1 (2.63)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.88

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.88 (24.57)
Research Supply Index3.76 (2.92)
Research Growth Index5.65 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.88)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other42 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]