urea has been researched along with Sepsis in 78 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Landiolol resulted in significantly more patients with sepsis-related tachyarrhythmia achieving a heart rate of 60-94 bpm at 24 h and significantly reduced the incidence of new-onset arrhythmia." | 9.34 | Efficacy and safety of landiolol, an ultra-short-acting β1-selective antagonist, for treatment of sepsis-related tachyarrhythmia (J-Land 3S): a multicentre, open-label, randomised controlled trial. ( Kakihana, Y; Matsuda, N; Morimatsu, H; Morishima, E; Nagano, T; Nishida, O; Ogura, H; Okajima, M; Taniguchi, T; Yamada, Y, 2020) |
| "Our aim was to compare the effects of intravenous, enteral, and enteral plus intravenous supplemented glutamine on plasma transferrin, nitrogen balance, and creatinine/height index in septic patients with malnutrition." | 9.19 | The effects of intravenous, enteral and combined administration of glutamine on malnutrition in sepsis: a randomized clinical trial. ( Erbabacan, E; Karaoren, G; Koksal, GM; Oz, H; Tunali, Y; Vehid, S, 2014) |
| "To evaluate the effect of enteral nutrition (EN) supplemented with l-glutamine on glycolytic parameters, inflammation, immune function, and oxidative stress in moderately ill intensive care patients with sepsis." | 9.16 | Enteral nutrition supplemented with L-glutamine in patients with systemic inflammatory response syndrome due to pulmonary infection. ( Campelo, MW; Cavalcante, AA; de Vasconcelos, MP; de Vasconcelos, PR; Ferreira, CM; Garcia, JH; Guimarães, SB, 2012) |
| "We aimed to evaluate whether the administration of riboflavin to septic animals reduces inflammation, oxidative stress, organ dysfunction, and mortality." | 8.12 | Riboflavin did not provide anti-inflammatory or antioxidant effects in an experimental model of sepsis. ( Alves-Filho, JC; Aragon, DC; Carlotti, APCP; Cunha, FQ; Ferreira, RG; Nascimento, DC; Pineros, AR; Ramalho, FS; Santos, JD; Vale, AHF, 2022) |
| "This study was performed to investigate the interrelationship between gluconeogenesis and ureagenesis during sepsis." | 7.68 | Interrelationship between hepatic ureagenesis and gluconeogenesis in early sepsis. ( Clemens, MG; Ohtake, Y, 1991) |
| "The kinetic interactions among glucose, alanine, and urea metabolism were studied in both normal volunteers and in patients with sepsis by means of a primed, constant infusion of stable isotopes." | 7.67 | Assessment of alanine, urea, and glucose interrelationships in normal subjects and in patients with sepsis with stable isotopic tracers. ( Klein, S; Shaw, JH; Wolfe, RR, 1985) |
| "We report a case of junctional ectopic tachycardia, preceded by sepsis, in a 4-year-old girl, 31 months after open-heart surgery." | 5.43 | Efficacy of landiolol for the treatment of junctional ectopic tachycardia resulting from sepsis. ( Azuma, H; Oka, H; Sugimoto, M, 2016) |
| "FeUrea was 39% (28 to 40) in the no-AKI group, 41% (29 to 54) in the transient AKI group and 32% (22 to 51) in the persistent AKI group (P = 0." | 5.37 | Diagnostic performance of fractional excretion of urea in the evaluation of critically ill patients with acute kidney injury: a multicenter cohort study. ( Bernardin, G; Brochard, L; Cohen, Y; Darmon, M; Das, V; Dellamonica, J; Gonzalez, F; Schlemmer, B; Schortgen, F; Vincent, F; Zeni, F, 2011) |
| "Landiolol resulted in significantly more patients with sepsis-related tachyarrhythmia achieving a heart rate of 60-94 bpm at 24 h and significantly reduced the incidence of new-onset arrhythmia." | 5.34 | Efficacy and safety of landiolol, an ultra-short-acting β1-selective antagonist, for treatment of sepsis-related tachyarrhythmia (J-Land 3S): a multicentre, open-label, randomised controlled trial. ( Kakihana, Y; Matsuda, N; Morimatsu, H; Morishima, E; Nagano, T; Nishida, O; Ogura, H; Okajima, M; Taniguchi, T; Yamada, Y, 2020) |
| "Our aim was to compare the effects of intravenous, enteral, and enteral plus intravenous supplemented glutamine on plasma transferrin, nitrogen balance, and creatinine/height index in septic patients with malnutrition." | 5.19 | The effects of intravenous, enteral and combined administration of glutamine on malnutrition in sepsis: a randomized clinical trial. ( Erbabacan, E; Karaoren, G; Koksal, GM; Oz, H; Tunali, Y; Vehid, S, 2014) |
| "To evaluate the effect of enteral nutrition (EN) supplemented with l-glutamine on glycolytic parameters, inflammation, immune function, and oxidative stress in moderately ill intensive care patients with sepsis." | 5.16 | Enteral nutrition supplemented with L-glutamine in patients with systemic inflammatory response syndrome due to pulmonary infection. ( Campelo, MW; Cavalcante, AA; de Vasconcelos, MP; de Vasconcelos, PR; Ferreira, CM; Garcia, JH; Guimarães, SB, 2012) |
| "The administration of branched-chain amino acids (BCAAs) has been proved useful in reducing both urea nitrogen production and muscle proteolysis in trauma patients with sepsis, but the optimum infusion rate to achieve these effects is still in question." | 5.07 | Leucine dose response in the reduction of urea production from septic proteolysis and in the stimulation of acute-phase proteins. ( Bruzzone, P; Chiarla, C; Goodarzi, S; Placko, R; Siegel, JH; Wiles, CE, 1991) |
| "We aimed to evaluate whether the administration of riboflavin to septic animals reduces inflammation, oxidative stress, organ dysfunction, and mortality." | 4.12 | Riboflavin did not provide anti-inflammatory or antioxidant effects in an experimental model of sepsis. ( Alves-Filho, JC; Aragon, DC; Carlotti, APCP; Cunha, FQ; Ferreira, RG; Nascimento, DC; Pineros, AR; Ramalho, FS; Santos, JD; Vale, AHF, 2022) |
| "The underlying pathophysiology of liver dysfunction in urea cycle disorders (UCDs) is still largely elusive." | 3.85 | Metabolically based liver damage pathophysiology in patients with urea cycle disorders - A new hypothesis. ( Garavelli, L; Ivanovski, A; Ivanovski, I; Ivanovski, P; Ješić, M, 2017) |
| "To validate the Mortality in Emergency Department Sepsis (MEDS) score, the Confusion, Urea nitrogen, Respiratory rate, Blood pressure, 65 years of age and older (CURB-65) score, and a modified Rapid Emergency Medicine Score (mREMS) in patients with suspected infection." | 3.74 | Performance of severity of illness scoring systems in emergency department patients with infection. ( Clardy, P; Donnino, MW; Howell, MD; Ngo, L; Shapiro, NI; Talmor, D, 2007) |
| "This study was performed to investigate the interrelationship between gluconeogenesis and ureagenesis during sepsis." | 3.68 | Interrelationship between hepatic ureagenesis and gluconeogenesis in early sepsis. ( Clemens, MG; Ohtake, Y, 1991) |
| " The following factors correlated with the severity of brain dysfunction: adult respiratory distress syndrome; fatal outcome; certain types of EEG abnormality; axonal peripheral neuropathy; elevated peripheral white blood cell count; elevated serum levels of alkaline phosphatase, bilirubin, creatinine, phosphate, potassium, and urea; reduced blood pressure and reduced serum albumin level." | 3.68 | The encephalopathy associated with septic illness. ( Archibald, YM; Austin, TW; Bolton, CF; Gonder, J; Wells, GA; Young, GB, 1990) |
| "The kinetic interactions among glucose, alanine, and urea metabolism were studied in both normal volunteers and in patients with sepsis by means of a primed, constant infusion of stable isotopes." | 3.67 | Assessment of alanine, urea, and glucose interrelationships in normal subjects and in patients with sepsis with stable isotopic tracers. ( Klein, S; Shaw, JH; Wolfe, RR, 1985) |
| "Sepsis is a life-threatening organ dysfunction condition response resulting in acute lung injury." | 1.51 | Urotensin receptors as a new target for CLP induced septic lung injury in mice. ( Akpinar, E; Cadirci, E; Cinar, I; Dincer, B; Gundogdu, B; Halici, Z; Ugan, RA, 2019) |
| "We report a case of junctional ectopic tachycardia, preceded by sepsis, in a 4-year-old girl, 31 months after open-heart surgery." | 1.43 | Efficacy of landiolol for the treatment of junctional ectopic tachycardia resulting from sepsis. ( Azuma, H; Oka, H; Sugimoto, M, 2016) |
| "Sepsis is the most common trigger for acute kidney injury (AKI) in critically ill patients." | 1.38 | A prospective evaluation of urine microscopy in septic and non-septic acute kidney injury. ( Bagshaw, SM; Bellomo, R; Bennett, M; Devarajan, P; Haase, M; Haase-Fielitz, A, 2012) |
| "FeUrea was 39% (28 to 40) in the no-AKI group, 41% (29 to 54) in the transient AKI group and 32% (22 to 51) in the persistent AKI group (P = 0." | 1.37 | Diagnostic performance of fractional excretion of urea in the evaluation of critically ill patients with acute kidney injury: a multicenter cohort study. ( Bernardin, G; Brochard, L; Cohen, Y; Darmon, M; Das, V; Dellamonica, J; Gonzalez, F; Schlemmer, B; Schortgen, F; Vincent, F; Zeni, F, 2011) |
| "We examined the influence of graft infection on serum creatinine levels in kidney recipients." | 1.37 | Graft infection in kidney recipients and its relation to transplanted kidney function. ( Biernawska, J; Bohatyrewicz, R; Brykczyński, M; Ciechanowicz, A; Kaczmarczyk, M; Kotfis, K; Nikodemski, T; Różański, J; Zegan-Barańska, M; Ziętek, Z; Zukowski, M, 2011) |
| "Hyperammonemia is encountered frequently in acutely ill children presenting for emergency care with altered levels of consciousness (ALOC)." | 1.36 | Hyperammonemia in the pediatric emergency care setting. ( Dabnon, M; Fouad, HM; Galal, NM; Saied, A, 2010) |
| " The pharmacokinetic profile of cefuroxime exhibited both one and two compartmental distribution." | 1.35 | Effect of severity disease on the pharmacokinetics of cefuroxime in children with multiple organ system failure. ( Asseff, IL; Guillé, GP; Olguín, HJ; Pérez, AG; Quesada, AC; Saldaña, NG; Vieyra, AC, 2008) |
| "Early AA administration was not associated with any clinically significant adverse effects; it was associated with reduction in the incidence of sepsis and marginally effective in reducing time to regain birth weight." | 1.33 | Safety and efficacy of early amino acids in preterm <28 weeks gestation: prospective observational comparison. ( Benadiba-Torch, A; Cuddy, A; Kotsopoulos, K; Shah, PS, 2006) |
| "Urea production was increased by alanine to a greater extent in the septic group compared to sham." | 1.29 | Hormone effects on hepatic substrate preference in sepsis. ( Clemens, MG; Paidas, CN, 1994) |
| "Urea- clones were also found in three of six other strains of P." | 1.26 | Unusual Enterobacteriaceae. "Proteus rettgeri" that "change" into Providencia stuartii. ( Brenner, DJ; Farmer, JJ; Hickman, FW; Rickenbach, DG; Schreiber, M, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (37.18) | 18.7374 |
| 1990's | 9 (11.54) | 18.2507 |
| 2000's | 9 (11.54) | 29.6817 |
| 2010's | 22 (28.21) | 24.3611 |
| 2020's | 9 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Ferrario, M | 1 |
| Pastorelli, R | 1 |
| Brunelli, L | 1 |
| Liu, S | 1 |
| Zanella do Amaral Campos, PP | 1 |
| Casoni, D | 1 |
| Z'Graggen, WJ | 1 |
| Jakob, SM | 1 |
| Vale, AHF | 1 |
| Nascimento, DC | 1 |
| Pineros, AR | 1 |
| Ferreira, RG | 1 |
| Santos, JD | 1 |
| Aragon, DC | 1 |
| Cunha, FQ | 1 |
| Ramalho, FS | 1 |
| Alves-Filho, JC | 1 |
| Carlotti, APCP | 1 |
| Alves, GF | 1 |
| Stoppa, I | 1 |
| Aimaretti, E | 1 |
| Monge, C | 1 |
| Mastrocola, R | 1 |
| Porchietto, E | 1 |
| Einaudi, G | 1 |
| Collotta, D | 1 |
| Bertocchi, I | 1 |
| Boggio, E | 1 |
| Gigliotti, CL | 1 |
| Clemente, N | 1 |
| Aragno, M | 1 |
| Fernandes, D | 1 |
| Cifani, C | 1 |
| Thiemermann, C | 1 |
| Dianzani, C | 1 |
| Dianzani, U | 1 |
| Collino, M | 1 |
| Zhai, B | 1 |
| Ma, LS | 1 |
| Shen, RQ | 1 |
| Yu, J | 1 |
| Tao, YN | 1 |
| Xu, AP | 1 |
| Shao, DC | 1 |
| Ibrahim, YF | 1 |
| Fadl, RR | 1 |
| Ibrahim, S | 1 |
| Gayyed, MF | 1 |
| Bayoumi, A | 1 |
| Refaie, M | 1 |
| Kakihana, Y | 1 |
| Nishida, O | 1 |
| Taniguchi, T | 1 |
| Okajima, M | 1 |
| Morimatsu, H | 1 |
| Ogura, H | 1 |
| Yamada, Y | 1 |
| Nagano, T | 1 |
| Morishima, E | 1 |
| Matsuda, N | 1 |
| Morelli, A | 1 |
| Whitehouse, T | 1 |
| Rehberg, S | 1 |
| Sivak, KV | 1 |
| Stosman, KI | 1 |
| Rassokha, TA | 1 |
| Aleksandrov, AG | 1 |
| Kuzmich, NN | 1 |
| Orshanskaya, YR | 1 |
| Savateeva-Lubimova, TN | 1 |
| Lesiovskaya, EE | 1 |
| Du, F | 1 |
| Sun, W | 1 |
| Morisseau, C | 1 |
| Hammock, BD | 1 |
| Bao, X | 1 |
| Liu, Q | 1 |
| Wang, C | 1 |
| Zhang, T | 1 |
| Yang, H | 1 |
| Zhou, J | 1 |
| Xiao, W | 1 |
| Liu, Z | 1 |
| Chen, G | 1 |
| Parkhomenko, E | 1 |
| De Fazio, A | 1 |
| Tran, T | 1 |
| Thai, J | 1 |
| Blum, K | 1 |
| Gupta, M | 1 |
| Ivanovski, I | 1 |
| Ješić, M | 1 |
| Ivanovski, A | 1 |
| Garavelli, L | 1 |
| Ivanovski, P | 1 |
| Mathieu, C | 1 |
| Desrois, M | 1 |
| Kober, F | 1 |
| Lalevée, N | 1 |
| Lan, C | 1 |
| Fourny, N | 1 |
| Iché-Torres, M | 1 |
| Tran, TT | 1 |
| Lê, LT | 1 |
| Singer, M | 1 |
| Mège, JL | 1 |
| Bernard, M | 1 |
| Leone, M | 1 |
| Cadirci, E | 1 |
| Ugan, RA | 1 |
| Dincer, B | 1 |
| Gundogdu, B | 1 |
| Cinar, I | 1 |
| Akpinar, E | 1 |
| Halici, Z | 1 |
| Schiffl, H | 1 |
| Fischer, R | 1 |
| Lang, SM | 1 |
| Koksal, GM | 1 |
| Erbabacan, E | 1 |
| Tunali, Y | 1 |
| Karaoren, G | 1 |
| Vehid, S | 1 |
| Oz, H | 1 |
| Seki, Y | 1 |
| Jesmin, S | 2 |
| Shimojo, N | 2 |
| Islam, MM | 1 |
| Rahman, MA | 1 |
| Khatun, T | 2 |
| Sakuramoto, H | 1 |
| Oki, M | 1 |
| Sonobe, A | 1 |
| Kamiyama, J | 1 |
| Hagiya, K | 1 |
| Kawano, S | 2 |
| Mizutani, T | 2 |
| Oka, H | 1 |
| Sugimoto, M | 1 |
| Azuma, H | 1 |
| Gasanov, MD | 1 |
| Schick, MA | 1 |
| Baar, W | 1 |
| Bruno, RR | 1 |
| Wollborn, J | 1 |
| Held, C | 1 |
| Schneider, R | 1 |
| Flemming, S | 1 |
| Schlegel, N | 1 |
| Roewer, N | 1 |
| Neuhaus, W | 1 |
| Wunder, C | 1 |
| Bojic, S | 1 |
| Kotur-Stevuljevic, J | 1 |
| Kalezic, N | 1 |
| Stevanovic, P | 1 |
| Jelic-Ivanovic, Z | 1 |
| Bilanovic, D | 1 |
| Memon, L | 1 |
| Damnjanovic, M | 1 |
| Kalaba, Z | 1 |
| Simic-Ogrizovic, S | 1 |
| Matsuishi, Y | 1 |
| Hideaki, S | 1 |
| Mowa, CN | 1 |
| Akhtar, S | 1 |
| Zaedi, S | 1 |
| Tsunoda, Y | 1 |
| Kiwamoto, T | 1 |
| Hizawa, N | 1 |
| Inoue, Y | 1 |
| Andrades, M | 1 |
| Ritter, C | 1 |
| de Oliveira, MR | 1 |
| Streck, EL | 1 |
| Fonseca Moreira, JC | 1 |
| Dal-Pizzol, F | 1 |
| Avila, TV | 1 |
| Bastos Pereira, AL | 1 |
| De Oliveira Christoff, A | 1 |
| Da Silva Soley, B | 1 |
| Queiroz Telles, JE | 1 |
| Eler, GJ | 1 |
| Bracht, A | 1 |
| Roberto Zampronio, A | 1 |
| Acco, A | 1 |
| Legido-Quigley, C | 1 |
| Cloarec, O | 1 |
| Parker, DA | 1 |
| Murphy, GM | 1 |
| Holmes, E | 1 |
| Lindon, JC | 1 |
| Nicholson, JK | 1 |
| Mitry, RR | 1 |
| Vilca-Melendez, H | 1 |
| Rela, M | 1 |
| Dhawan, A | 1 |
| Heaton, N | 1 |
| Galal, NM | 1 |
| Fouad, HM | 1 |
| Saied, A | 1 |
| Dabnon, M | 1 |
| Bagshaw, SM | 2 |
| Haase, M | 1 |
| Haase-Fielitz, A | 1 |
| Bennett, M | 2 |
| Devarajan, P | 2 |
| Bellomo, R | 2 |
| Darmon, M | 1 |
| Vincent, F | 1 |
| Dellamonica, J | 1 |
| Schortgen, F | 1 |
| Gonzalez, F | 1 |
| Das, V | 1 |
| Zeni, F | 1 |
| Brochard, L | 1 |
| Bernardin, G | 1 |
| Cohen, Y | 1 |
| Schlemmer, B | 1 |
| Zukowski, M | 1 |
| Kotfis, K | 1 |
| Biernawska, J | 1 |
| Zegan-Barańska, M | 1 |
| Kaczmarczyk, M | 1 |
| Ciechanowicz, A | 1 |
| Brykczyński, M | 1 |
| Różański, J | 1 |
| Ziętek, Z | 1 |
| Nikodemski, T | 1 |
| Bohatyrewicz, R | 1 |
| Cavalcante, AA | 1 |
| Campelo, MW | 1 |
| de Vasconcelos, MP | 1 |
| Ferreira, CM | 1 |
| Guimarães, SB | 1 |
| Garcia, JH | 1 |
| de Vasconcelos, PR | 1 |
| Saha, M | 1 |
| Aich, T | 1 |
| Das, C | 1 |
| Mukhopadhyay, M | 1 |
| Patar, K | 1 |
| Stuart-Clark, H | 1 |
| Vorajee, N | 1 |
| Zuma, S | 1 |
| Van Niekerk, L | 1 |
| Burch, V | 1 |
| Raubenheimer, P | 1 |
| Peter, JG | 1 |
| Hackbarth, CJ | 1 |
| Chen, DZ | 1 |
| Lewis, JG | 1 |
| Clark, K | 1 |
| Mangold, JB | 1 |
| Cramer, JA | 1 |
| Margolis, PS | 1 |
| Wang, W | 1 |
| Koehn, J | 1 |
| Wu, C | 1 |
| Lopez, S | 1 |
| Withers, G | 1 |
| Gu, H | 1 |
| Dunn, E | 1 |
| Kulathila, R | 1 |
| Pan, SH | 1 |
| Porter, WL | 1 |
| Jacobs, J | 1 |
| Trias, J | 1 |
| Patel, DV | 1 |
| Weidmann, B | 1 |
| White, RJ | 1 |
| Yuan, Z | 1 |
| Ruiz-Perez, B | 1 |
| Cisneros, RL | 1 |
| Matsumoto, T | 1 |
| Miller, RJ | 1 |
| Vasios, G | 1 |
| Calias, P | 1 |
| Onderdonk, AB | 1 |
| BALS, M | 1 |
| SERBANESCU, F | 1 |
| CARUNTU, F | 1 |
| TAINDEL, C | 1 |
| JIPA, R | 1 |
| PREDOVICIU, FM | 1 |
| HULME, B | 1 |
| KNIGHT, PR | 1 |
| ELKINGTON, JS | 1 |
| BLAINEY, JD | 1 |
| DAWSON-EDWARDS, P | 1 |
| Yoshida, Y | 1 |
| Hongo, T | 1 |
| Sakamoto, A | 1 |
| Ogawa, R | 1 |
| Struck, J | 1 |
| Uhlein, M | 1 |
| Morgenthaler, NG | 1 |
| Fürst, W | 1 |
| Höflich, C | 1 |
| Bahrami, S | 1 |
| Bergmann, A | 1 |
| Volk, HD | 1 |
| Redl, H | 1 |
| Tang, J | 1 |
| Cheung, PS | 1 |
| Kotsopoulos, K | 1 |
| Benadiba-Torch, A | 1 |
| Cuddy, A | 1 |
| Shah, PS | 1 |
| Howell, MD | 1 |
| Donnino, MW | 1 |
| Talmor, D | 1 |
| Clardy, P | 1 |
| Ngo, L | 1 |
| Shapiro, NI | 1 |
| Olguín, HJ | 1 |
| Asseff, IL | 1 |
| Vieyra, AC | 1 |
| Pérez, AG | 1 |
| Saldaña, NG | 1 |
| Quesada, AC | 1 |
| Guillé, GP | 1 |
| Gibson, DG | 1 |
| Mickell, JJ | 1 |
| Paidas, CN | 1 |
| Clemens, MG | 2 |
| Dahn, MS | 3 |
| Lange, MP | 3 |
| Berberoglu, ED | 1 |
| Andrejko, KM | 1 |
| Deutschman, CS | 1 |
| Mayser, P | 1 |
| Imkampe, A | 1 |
| Winkeler, M | 1 |
| Papavassilis, C | 1 |
| Amyot, SL | 1 |
| Leblanc, M | 1 |
| Thibeault, Y | 1 |
| Geadah, D | 1 |
| Cardinal, J | 1 |
| Shanson, DC | 1 |
| Kensit, J | 1 |
| Hince, C | 1 |
| Farmer, JJ | 1 |
| Hickman, FW | 1 |
| Brenner, DJ | 1 |
| Schreiber, M | 1 |
| Rickenbach, DG | 1 |
| McDougal, WS | 1 |
| Wilmore, DW | 1 |
| Pruitt, BA | 1 |
| Bruzzone, P | 1 |
| Siegel, JH | 1 |
| Chiarla, C | 1 |
| Wiles, CE | 1 |
| Placko, R | 1 |
| Goodarzi, S | 1 |
| Ohtake, Y | 1 |
| Young, GB | 1 |
| Bolton, CF | 1 |
| Austin, TW | 1 |
| Archibald, YM | 1 |
| Gonder, J | 1 |
| Wells, GA | 1 |
| Lehmkuhl, P | 1 |
| Schultz, A | 1 |
| Gebert, J | 1 |
| Roth, E | 1 |
| Jacobs, LA | 1 |
| Hernández, G | 1 |
| Celis, R | 1 |
| Bavestrello, L | 1 |
| Nercelles, P | 1 |
| Barros, M | 1 |
| González, R | 1 |
| Toro, J | 1 |
| Nelson, J | 1 |
| Ormrod, DJ | 1 |
| Miller, TE | 1 |
| Shaw, JH | 1 |
| Klein, S | 1 |
| Wolfe, RR | 1 |
| Cerra, FB | 1 |
| Shronts, EP | 1 |
| Konstantinides, NN | 1 |
| Thoele, S | 1 |
| Konstantinides, FN | 1 |
| Teasley, K | 1 |
| Lysne, J | 1 |
| Fauser, U | 1 |
| Douglas, RM | 1 |
| Devitt, L | 1 |
| Macartney, B | 1 |
| Asbach, HW | 1 |
| Stoeckel, H | 1 |
| Schüler, HW | 1 |
| Conradi, R | 1 |
| Wiedemann, K | 1 |
| Möhring, K | 1 |
| Röhl, L | 1 |
| Bottomley, JP | 1 |
| Bradley, J | 1 |
| Whitehouse, GH | 1 |
| Vachon, F | 1 |
| Carbon, C | 1 |
| Josse, RG | 1 |
| Malchow, H | 1 |
| Seybold, D | 1 |
| Lange, H | 1 |
| Freund, J | 1 |
| Rüger, K | 1 |
| Preston, FE | 1 |
| Malia, RG | 1 |
| Sworn, MJ | 1 |
| Blackburn, EK | 1 |
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| Varghese, Z | 1 |
| Fernando, ON | 1 |
| Baillod, R | 1 |
| Hopewell, JP | 1 |
| Moorhead, JF | 1 |
| Kinney, JM | 1 |
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| Better, OS | 1 |
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| Barzilai, A | 1 |
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| Sforza, F | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Controlled Trial of an Integrated Post-discharge Transitional Care Package for General Medical In-patients in Cape Town, South Africa[NCT01916876] | 0 participants (Actual) | Interventional | 2015-03-31 | Withdrawn (stopped due to Funding shortage) | |||
| "Validation Study of the 4-question RACYDelirium Screening Tool in General Medical In-patients From a Developing Country Setting"[NCT01916889] | 1,093 participants (Actual) | Interventional | 2013-09-30 | Completed | |||
| Effects of High vs. Standard Protein Intake in the Weight Gain and Renal Function Security in Newborn Extreme Premature[NCT02478086] | Phase 2 | 52 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for urea and Sepsis
| Article | Year |
|---|---|
Energy and tissue fuel in human injury and sepsis.
Topics: Body Weight; Energy Metabolism; Female; Gluconeogenesis; Glucose; Humans; Liver; Male; Nitrogen; Oxi | 1972 |
6 trials available for urea and Sepsis
| Article | Year |
|---|---|
Efficacy and safety of landiolol, an ultra-short-acting β1-selective antagonist, for treatment of sepsis-related tachyarrhythmia (J-Land 3S): a multicentre, open-label, randomised controlled trial.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Female; Humans; Male; Morpholines; Sepsis; Tachycardia | 2020 |
The effects of intravenous, enteral and combined administration of glutamine on malnutrition in sepsis: a randomized clinical trial.
Topics: Adult; Aged; Creatinine; Dietary Proteins; Dietary Supplements; Energy Intake; Enteral Nutrition; Fe | 2014 |
Enteral nutrition supplemented with L-glutamine in patients with systemic inflammatory response syndrome due to pulmonary infection.
Topics: Adult; Aged; Aged, 80 and over; Caseins; Dietary Supplements; Double-Blind Method; Enteral Nutrition | 2012 |
Leucine dose response in the reduction of urea production from septic proteolysis and in the stimulation of acute-phase proteins.
Topics: Acute-Phase Proteins; Adult; Amino Acids, Branched-Chain; Energy Intake; Female; Humans; Leucine; Ma | 1991 |
Insulinlike growth factor 1 production is inhibited in human sepsis.
Topics: Adult; Amino Acids; Blood Glucose; Glucose; Growth Hormone; Humans; Insulin-Like Growth Factor I; Mi | 1988 |
Enteral feeding in sepsis: a prospective, randomized, double-blind trial.
Topics: Adolescent; Adult; Aged; Amino Acids, Branched-Chain; Clinical Trials as Topic; Double-Blind Method; | 1985 |
71 other studies available for urea and Sepsis
| Article | Year |
|---|---|
Persistent hyperammonia and altered concentrations of urea cycle metabolites in a 5-day swine experiment of sepsis.
Topics: Ammonia; Animals; Cytokines; Female; Glucose; Lipid Metabolism; Male; Metabolome; Sepsis; Swine; Ure | 2021 |
Riboflavin did not provide anti-inflammatory or antioxidant effects in an experimental model of sepsis.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Bayes Theorem; Chemokines; C | 2022 |
ICOS-Fc as innovative immunomodulatory approach to counteract inflammation and organ injury in sepsis.
Topics: Animals; Creatinine; Cytokines; Immune Checkpoint Proteins; Immunity; Immunomodulation; Inducible T- | 2022 |
[Caspase-1/-11 participates in LPS-induced sepsis-associated acute kidney injury by cleaving GSDMD].
Topics: Acute Kidney Injury; Animals; Caspase 1; Caspases; Creatinine; Gasdermins; Lipopolysaccharides; Mice | 2023 |
Protective effect of febuxostat in sepsis-induced liver and kidney injuries after cecal ligation and puncture with the impact of xanthine oxidase, interleukin 1
Topics: Acute Kidney Injury; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cecum; Creatinine; | 2020 |
β-blockade in sepsis: regulation of persisting sepsis-related tachycardia.
Topics: Humans; Morpholines; Sepsis; Tachycardia; Urea | 2020 |
The Effect of TLR4 Blockade on Some Indicators of Systemic Inflammatory Response to Proteus mirabilis LPS in Rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Animals, Outbred Strains; Anti-Inflammatory Age | 2020 |
Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis.
Topics: Animals; Binding Sites; Catalytic Domain; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Ep | 2021 |
A Multi-Institutional Study of Struvite Stones: Patterns of Infection and Colonization.
Topics: Adult; Enterococcus; Escherichia coli; Escherichia coli Infections; Female; Humans; Kidney Calculi; | 2017 |
Metabolically based liver damage pathophysiology in patients with urea cycle disorders - A new hypothesis.
Topics: Ammonia; Central Nervous System; Citrullinemia; Enterobacter; Fatal Outcome; Hepatocytes; Humans; Hy | 2017 |
Sex-Mediated Response to the Beta-Blocker Landiolol in Sepsis: An Experimental, Randomized Study.
Topics: Adrenergic beta-Antagonists; Animals; Female; Heart; Magnetic Resonance Imaging; Male; Morpholines; | 2018 |
Urotensin receptors as a new target for CLP induced septic lung injury in mice.
Topics: Acute Lung Injury; Animals; Cecum; Cytokines; Gene Expression; Glutathione; Ligation; Lung; Male; Ma | 2019 |
Assessment of dialysis dose in critically ill maintenance dialysis patients.
Topics: Aged; Aged, 80 and over; APACHE; Critical Illness; Dialysis Solutions; Female; Hospital Mortality; H | 2014 |
Significant reversal of cardiac upregulated endothelin-1 system in a rat model of sepsis by landiolol hydrochloride.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Endothelin-1; Hemodynamics; Interleukin-6; Male | 2014 |
Efficacy of landiolol for the treatment of junctional ectopic tachycardia resulting from sepsis.
Topics: Anti-Arrhythmia Agents; Child, Preschool; Female; Humans; Morpholines; Sepsis; Tachycardia, Ectopic | 2016 |
[Рformation of algorithms to determine the severity of endotoxemia in peritonitis].
Topics: Abdominal Cavity; Adult; Algorithms; Drainage; Endotoxemia; Female; Humans; Male; Malondialdehyde; P | 2015 |
Balanced Hydroxyethylstarch (HES 130/0.4) Impairs Kidney Function In-Vivo without Inflammation.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Blood Urea Nitrogen; Cell Line; Cell | 2015 |
Diagnostic Value of Matrix Metalloproteinase-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 in Sepsis-Associated Acute Kidney Injury.
Topics: Abdomen; Acute Lung Injury; Acute-Phase Proteins; Aged; Creatinine; Critical Care; Disease Progressi | 2015 |
Landiolol hydrochloride ameliorates acute lung injury in a rat model of early sepsis through the suppression of elevated levels of pulmonary endothelin-1.
Topics: Acute Lung Injury; Adrenergic beta-Antagonists; Animals; Down-Regulation; Endothelin-1; Lung; Male; | 2016 |
Antioxidant treatment reverses organ failure in rat model of sepsis: role of antioxidant enzymes imbalance, neutrophil infiltration, and oxidative stress.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Deferoxamine; Disease Models, Animal; Kidney; Lung; | 2011 |
Hepatic effects of flunixin-meglumin in LPS-induced sepsis.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspartate Amin | 2010 |
First example of hepatocyte transplantation to alleviate ornithine transcarbamylase deficiency, monitored by NMR-based metabonomics.
Topics: Ammonia; Hepatocytes; Humans; Infant; Infant, Newborn; Liver Transplantation; Magnetic Resonance Spe | 2009 |
Hyperammonemia in the pediatric emergency care setting.
Topics: Ammonia; Brain Damage, Chronic; Child; Child, Preschool; Consciousness Disorders; Critical Illness; | 2010 |
A prospective evaluation of urine microscopy in septic and non-septic acute kidney injury.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Cohort Studies; Creatinine; Critical Illness; Disease | 2012 |
Diagnostic performance of fractional excretion of urea in the evaluation of critically ill patients with acute kidney injury: a multicenter cohort study.
Topics: Acute Kidney Injury; Aged; Biomarkers; Cohort Studies; Critical Illness; Diuretics; Female; Hemodyna | 2011 |
Graft infection in kidney recipients and its relation to transplanted kidney function.
Topics: Adolescent; Adult; Child; Creatinine; Female; Humans; Infections; Kidney Diseases; Kidney Function T | 2011 |
Medical image. Septicaemia with acute renal failure.
Topics: Acute Kidney Injury; Adult; Fatal Outcome; Humans; Kidney Tubules; Male; Necrosis; Sepsis; Sweat; Ur | 2012 |
Twelve-month outcomes of patients admitted to the acute general medical service at Groote Schuur Hospital.
Topics: Activities of Daily Living; Adult; Age Factors; Aged; Confidence Intervals; Employment; Female; Foll | 2012 |
Twelve-month outcomes of patients admitted to the acute general medical service at Groote Schuur Hospital.
Topics: Activities of Daily Living; Adult; Age Factors; Aged; Confidence Intervals; Employment; Female; Foll | 2012 |
Twelve-month outcomes of patients admitted to the acute general medical service at Groote Schuur Hospital.
Topics: Activities of Daily Living; Adult; Age Factors; Aged; Confidence Intervals; Employment; Female; Foll | 2012 |
Twelve-month outcomes of patients admitted to the acute general medical service at Groote Schuur Hospital.
Topics: Activities of Daily Living; Adult; Age Factors; Aged; Confidence Intervals; Employment; Female; Foll | 2012 |
Urine biochemistry in septic and non-septic acute kidney injury: a prospective observational study.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; APACHE; Area Under Curve; Biomarkers; Chi-Square Di | 2013 |
N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity.
Topics: Amidohydrolases; Aminopeptidases; Animals; Bacteria; Biotransformation; Crystallography, X-Ray; DNA | 2002 |
Protection against lethal intra-abdominal sepsis by 1-(3-dimethylaminopropyl)-3-ethylurea.
Topics: Abdominal Abscess; Adjuvants, Immunologic; Animals; Carboxymethylcellulose Sodium; Cytokines; Diseas | 2003 |
[ACUTE AZOTEMIAS DURING INFECTIOUS DISEASES].
Topics: Azotemia; Dysentery; Foodborne Diseases; Humans; Infections; Leptospirosis; Nitrogen; Sepsis; Tetanu | 1964 |
EVALUATION OF SIMULTANEOUS SPLIT-COIL HAEMODIALYSIS WITH THE KOLFF TWIN-COIL ARTIFICIAL KIDNEY.
Topics: Abortion, Septic; Acute Kidney Injury; Appendectomy; Blood; Cholecystectomy; Female; Hemorrhage; Hum | 1965 |
Successful management of tachycardiac atrial fibrillation in a septic patient with landiolol.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Hemodynamics; Humans; Intraoperative Complication | 2005 |
Release of the mitochondrial enzyme carbamoyl phosphate synthase under septic conditions.
Topics: Animals; Arginine; Bilirubin; Blotting, Western; Carbamoyl-Phosphate Synthase (Ammonia); Electrophor | 2005 |
A 77-year-old woman with sudden onset of blue discolouration of right third toe.
Topics: Aged; Blue Toe Syndrome; Creatinine; Dyspnea; Fatal Outcome; Female; Heart Diseases; Humans; Renal I | 2006 |
Safety and efficacy of early amino acids in preterm <28 weeks gestation: prospective observational comparison.
Topics: Amino Acids; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Male; Observation; | 2006 |
Performance of severity of illness scoring systems in emergency department patients with infection.
Topics: Adult; Aged; Area Under Curve; Blood Pressure Determination; Emergency Medicine; Emergency Service, | 2007 |
Effect of severity disease on the pharmacokinetics of cefuroxime in children with multiple organ system failure.
Topics: Adolescent; Alanine Transaminase; Algorithms; Area Under Curve; Aspartate Aminotransferases; Cefurox | 2008 |
Abnormal splitting of the second heart sound in renal failure.
Topics: Adult; Bicarbonates; Blood Pressure; Glomerulonephritis; Heart; Hemoglobinometry; Humans; Hypertensi | 1967 |
Urea nitrogen excretion in critically ill children.
Topics: Adolescent; Body Surface Area; Child; Child Nutritional Physiological Phenomena; Child, Preschool; D | 1982 |
Hormone effects on hepatic substrate preference in sepsis.
Topics: Alanine; Animals; Energy Metabolism; Gluconeogenesis; Hormones; Lactates; Lactic Acid; Liver; Male; | 1994 |
Functional characteristics of the hypermetabolic isolated perfused liver.
Topics: Adenine Nucleotides; Amino Acids; Animals; Energy Metabolism; Fibrinogen; Glucagon; Glucose; In Vitr | 1996 |
Altered hepatic gene expression in fecal peritonitis: changes in transcription of gluconeogenic, beta-oxidative, and ureagenic genes.
Topics: Administration, Cutaneous; Animals; Carnitine O-Palmitoyltransferase; Cecum; Feces; Gene Expression; | 1997 |
Systemic and splanchnic metabolic response to exogenous human growth hormone.
Topics: APACHE; C-Peptide; C-Reactive Protein; Critical Illness; Energy Intake; Hemodynamics; Human Growth H | 1998 |
Growth requirements and nitrogen metabolism of Malassezia furfur.
Topics: Allantoin; Amino Acids; Ammonium Chloride; Ammonium Sulfate; Cell Division; Creatine; Creatinine; Cu | 1998 |
Myoglobin clearance and removal during continuous venovenous hemofiltration.
Topics: Acrylic Resins; Acute Kidney Injury; Adult; Creatinine; Dehydration; Diabetes Mellitus, Type 2; Hemo | 1999 |
Letter: Uraemia, gram-negative sepsis, and gentamicin assays.
Topics: Biological Assay; Culture Media; Evaluation Studies as Topic; Gentamicins; Humans; Sepsis; Urea; Ure | 1975 |
Unusual Enterobacteriaceae. "Proteus rettgeri" that "change" into Providencia stuartii.
Topics: Aged; Ammonia; Bacteriological Techniques; Carbohydrate Metabolism; Humans; Lactose Factors; Male; P | 1977 |
Glucose-dependent hepatic membrane transport in nonbacteremic and bacteremic thermally injured patients.
Topics: Adolescent; Adult; Aged; Amino Acids; Biological Transport; Burns; Coloring Agents; Glucose; Humans; | 1977 |
Interrelationship between hepatic ureagenesis and gluconeogenesis in early sepsis.
Topics: Alanine; Ammonium Chloride; Animals; Gluconeogenesis; Glutamine; In Vitro Techniques; Kinetics; Lact | 1991 |
The encephalopathy associated with septic illness.
Topics: Alkaline Phosphatase; Bilirubin; Brain; Brain Diseases; Candida albicans; Creatinine; Electroencepha | 1990 |
Risk factors of the multiple organ failure.
Topics: Adolescent; Adult; Blood Coagulation Factors; Catecholamines; Creatinine; Female; Humans; Male; Midd | 1989 |
[Evaluation of the efficiency of parenteral nutrition].
Topics: Amino Acids; Blood Glucose; Blood Proteins; Energy Metabolism; Humans; Liver Diseases; Nitrogen; Par | 1986 |
[Value of urea nitrogen in the urine as a discriminating parameter of clinical sepsis].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Nitrogen; Sepsis; Ure | 1987 |
Host immune status in uraemia. VI. Leucocytic response to bacterial infection in chronic renal failure.
Topics: Animals; Escherichia coli Infections; Female; Kidney Failure, Chronic; Leukocytes; Lung Diseases; Ma | 1985 |
Assessment of alanine, urea, and glucose interrelationships in normal subjects and in patients with sepsis with stable isotopic tracers.
Topics: Adult; Aged; Alanine; Blood Glucose; Candidiasis; Carbon Isotopes; Escherichia coli Infections; Fema | 1985 |
[Successful treatment of Candida septicaemia and interstitial pneumonia].
Topics: Adult; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Benzene Derivatives; Bronchopneumon | 1973 |
Elevation of serum bilirubin and blood urea in pneumonia.
Topics: Adult; Bilirubin; Creatinine; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Male; | 1974 |
The treatment of hypercatabolic acute renal failure by adequate nutrition and haemodialysis.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Child; Child, Preschool; Creatinine; Diuresis; Humans; | 1974 |
Waldenstrom's macroglobulinaemia and amyloidosis with subcutaneous calcification and lymphographic appearances.
Topics: Amyloidosis; Biopsy; Bone Marrow Cells; Calcinosis; Calcium; Cardiomegaly; Cyclophosphamide; Hematoc | 1974 |
[Reputedly nephrotoxic antibiotic therapy during severe infections].
Topics: Acute Kidney Injury; Adolescent; Adult; Amphotericin B; Anti-Bacterial Agents; Bacterial Infections; | 1972 |
Editorial: Mid-trimester termination.
Topics: Abortion, Therapeutic; Female; Glucose; Humans; Hypernatremia; Hysterectomy; Oxytocin; Pregnancy; Pr | 1974 |
Gram-positive septicaemia in rheumatoid arthritis.
Topics: Ampicillin; Arthritis, Rheumatoid; Fusidic Acid; Humans; Lincomycin; Male; Middle Aged; Penicillin R | 1974 |
[Successful treatment of candida sepsis with the oral antimycotic Bay b 5097].
Topics: Acute Kidney Injury; Antifungal Agents; Benzene Derivatives; Blood; Candidiasis; Creatinine; Eye Man | 1972 |
Intravascular coagulation and E. coli septicaemia.
Topics: Anemia, Hemolytic; Autopsy; Blood Coagulation Tests; Blood Platelets; Disseminated Intravascular Coa | 1973 |
Serum IgG and renal transplantation.
Topics: Adult; Azathioprine; Creatinine; Escherichia coli Infections; Female; Graft Rejection; Hematocrit; H | 1973 |
Traumatic hepatorenal failure. Supportive treatment with simultaneous hemodialysis and exchange transfusion.
Topics: Acute Kidney Injury; Adult; Bilirubin; Blast Injuries; Blood Urea Nitrogen; Calcium; Citrates; Excha | 1972 |
Neonatal bacteriuria: a prospective study in 1,460 infants.
Topics: Bacteriuria; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Leukocyte Count; Male; Pros | 1972 |
Urea as a culture medium enriching agent for the early detection of septicemia in renal failure.
Topics: Blood Urea Nitrogen; Culture Media; Humans; Kidney Failure, Chronic; Sepsis; Urea | 1968 |
[The ureic index: clinical guide to mannitol treatment in pediatric surgery].
Topics: Acute Kidney Injury; Child; Child, Preschool; Female; Humans; Infant; Male; Mannitol; Postoperative | 1969 |