chlorine and Sepsis
chlorine has been researched along with Sepsis in 29 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sepsis is the most important trigger for acute renal failure, with tubular dysfunction and collapse in urine concentration." | 1.34 | Proinflammatory cytokines cause down-regulation of renal chloride entry pathways during sepsis. ( Bucher, M; Höcherl, K; Schmidt, C; Schweda, F, 2007) |
| "Platelet thrombus growth after FeCl(3)-induced acute endothelial injury was accelerated in mutant mice." | 1.31 | Characterization of a mouse model for thrombomodulin deficiency. ( Conway, EM; Cooley, BC; Hendrickson, SB; Isermann, BH; Kerlin, B; Lindner, V; Meh, DA; Mosesson, MW; Post, MJ; Shworak, NW; Ulfman, LH; von Andrian, UH; Weiler, H; Weitz, JI, 2001) |
| "Hyponatremia was not observed." | 1.28 | Fluid and ion redistribution in skeletal muscle in an animal sepsis model. ( Boston, VE; Hannon, RJ, 1990) |
Research
Studies (29)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (55.17) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 7 (24.14) | 29.6817 |
| 2010's | 4 (13.79) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Tehranian, S | 1 |
| Shawwa, K | 1 |
| Barreto, EF | 1 |
| Clements, CM | 1 |
| Kashani, K | 1 |
| Morrell, ED | 1 |
| Kellum, JA | 1 |
| Hallows, KR | 1 |
| Pastor-Soler, NM | 1 |
| Guirgis, FW | 1 |
| Williams, DJ | 1 |
| Hale, M | 1 |
| Bajwa, AA | 1 |
| Shujaat, A | 1 |
| Patel, N | 1 |
| Kalynych, CJ | 1 |
| Jones, AE | 1 |
| Wears, RL | 1 |
| Dodani, S | 1 |
| Quinten, VM | 1 |
| van Meurs, M | 1 |
| Ter Maaten, JC | 1 |
| Ligtenberg, JJ | 1 |
| Yunos, NM | 1 |
| Bellomo, R | 1 |
| Story, D | 1 |
| Kellum, J | 1 |
| OYAGUE CANEPA, E | 1 |
| SOIVA, K | 1 |
| PARVIAINEN, S | 1 |
| USOV, DV | 1 |
| VARLAMOVA, VP | 1 |
| Eisenhut, M | 2 |
| Sidaras, D | 1 |
| Barton, P | 1 |
| Newland, P | 1 |
| Southern, KW | 1 |
| O'Dell, E | 1 |
| Tibby, SM | 1 |
| Durward, A | 1 |
| Aspell, J | 1 |
| Murdoch, IA | 1 |
| Collins, KA | 1 |
| Presnell, SE | 1 |
| Anderson, RJ | 1 |
| Schmidt, C | 1 |
| Höcherl, K | 1 |
| Schweda, F | 1 |
| Bucher, M | 1 |
| Strauch, M | 1 |
| McLaughlin, JS | 1 |
| Mansberger, A | 1 |
| Young, J | 1 |
| Mendonca, P | 1 |
| Gray, K | 1 |
| Cowley, RA | 1 |
| Tucker, CS | 1 |
| MacMillan, JR | 1 |
| Schwedler, TE | 1 |
| Weiler, H | 1 |
| Lindner, V | 1 |
| Kerlin, B | 1 |
| Isermann, BH | 1 |
| Hendrickson, SB | 1 |
| Cooley, BC | 1 |
| Meh, DA | 1 |
| Mosesson, MW | 1 |
| Shworak, NW | 1 |
| Post, MJ | 1 |
| Conway, EM | 1 |
| Ulfman, LH | 1 |
| von Andrian, UH | 1 |
| Weitz, JI | 1 |
| Nichols, BL | 1 |
| Bilbrey, GL | 1 |
| Hazlewood, CF | 1 |
| Kimzey, SL | 1 |
| Liu, CT | 1 |
| Viteri, DF | 1 |
| Alvarado, J | 1 |
| Beisel, WR | 1 |
| Ciampolini, M | 1 |
| Karlen, JR | 1 |
| Piver, MS | 1 |
| Hannon, RJ | 1 |
| Boston, VE | 1 |
| Shiono, S | 1 |
| Fantini, GA | 1 |
| Roberts, JP | 1 |
| Chiao, J | 1 |
| Shires, GT | 1 |
| Rabsch, W | 1 |
| Reissbrodt, R | 1 |
| Rosendal, K | 1 |
| Bülow, P | 1 |
| Chan, JC | 1 |
| Bywater, RJ | 1 |
| Logan, EF | 1 |
| Bouckaert, A | 1 |
| Klein, F | 1 |
| Walker, JS | 1 |
| Fitzpatrick, DF | 1 |
| Lincoln, RE | 1 |
| Mahlandt, BG | 1 |
| Jones, WI | 1 |
| Dobbs, JP | 1 |
| Hendrix, KJ | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pirfenidone Effect on the Recovery of Renal Function in Patients With Septic Acute Kidney Injury[NCT02530359] | Phase 4 | 90 participants (Anticipated) | Interventional | 2015-10-31 | Not yet recruiting | ||
| Incidence of Acute Kidney Injury and Mortality in Critically Ill Patients: Urinary Chloride as a Prognostic Marker[NCT05542927] | 90 participants (Anticipated) | Observational [Patient Registry] | 2022-09-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
3 reviews available for chlorine and Sepsis
| Article | Year |
|---|---|
Epithelial transport during septic acute kidney injury.
Topics: Acute Kidney Injury; Animals; Chlorides; Epithelial Cells; Humans; Ion Transport; Sepsis | 2014 |
Bench-to-bedside review: Chloride in critical illness.
Topics: Acid-Base Equilibrium; Animals; Chloride Channels; Chlorides; Critical Care; Critical Illness; Fluid | 2010 |
[Disorders of electrolyte metabolism in the course of the intestinal radiosyndrome].
Topics: Animals; Bicarbonates; Bile; Calcium; Chlorides; Cysteamine; Dogs; Immunoglobulins; Intestinal Absor | 1968 |
Trials
1 trial available for chlorine and Sepsis
| Article | Year |
|---|---|
Elevated sweat sodium associated with pulmonary oedema in meningococcal sepsis.
Topics: Child; Chlorides; Female; Humans; Male; Meningococcal Infections; Pulmonary Edema; Sepsis; Sodium; S | 2004 |
Other Studies
25 other studies available for chlorine and Sepsis
| Article | Year |
|---|---|
Impact of chloride-rich crystalloids on sepsis-associated community-acquired acute kidney injury recovery in critically ill patients.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Chlorides; Cohort Studies; Critical Illness; Cr | 2022 |
The relationship of intravenous fluid chloride content to kidney function in patients with severe sepsis or septic shock.
Topics: Acute Kidney Injury; Aged; Chlorides; Creatinine; Female; Fluid Therapy; Humans; Length of Stay; Lin | 2015 |
Trends in vital signs and routine biomarkers in patients with sepsis during resuscitation in the emergency department: a prospective observational pilot study.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflam | 2016 |
Chloremia in toxic infant syndrome.
Topics: Blood; Chlorides; Female; Food; Humans; Pre-Eclampsia; Pregnancy; Sepsis; Toxemia | 1946 |
On the sodium, potassium and chloride concentrations of saliva in pregnancy and in toxaemia of late pregnancy.
Topics: Adrenal Cortex; Adrenal Cortex Function Tests; Chlorides; Female; Humans; Potassium; Pre-Eclampsia; | 1955 |
[A case of septicemia treated with antibiotics and calcium chloride].
Topics: Anti-Bacterial Agents; Calcium; Calcium Chloride; Chlorides; Sepsis | 1962 |
[STUDY OF THE BLOOD SERUM MINERAL COMPOSITION IN CHILDREN WITH SEPSIS].
Topics: Blood Chemical Analysis; Calcium; Calcium, Dietary; Child; Chlorides; Humans; Infant; Infant, Newbor | 1963 |
Validation of a method to partition the base deficit in meningococcal sepsis: a retrospective study.
Topics: Acid-Base Imbalance; Blood Chemical Analysis; Child; Child, Preschool; Chlorides; Cohort Studies; Hu | 2005 |
Re: "Circulating levels of KL-6 in acute respiratory distress syndrome sepsis or traumatic brain injury in critically ill children" by Briassoulis et al. (Pediatr Pulmonol 2006; 41:790-795).
Topics: Adrenergic beta-Agonists; Brain Injuries; Chloride Channels; Chlorides; Cyclic AMP; Cystic Fibrosis | 2006 |
Elder neglect and the pathophysiology of aging.
Topics: Aged; Aged, 80 and over; Aging; Bacteremia; Blood Urea Nitrogen; Cachexia; Chlorides; Dehydration; E | 2007 |
Kidney in sepsis.
Topics: Acute Kidney Injury; Animals; Chlorides; Cytokines; Humans; Kidney; Mice; Sepsis | 2007 |
Proinflammatory cytokines cause down-regulation of renal chloride entry pathways during sepsis.
Topics: Animals; Chlorides; CLC-2 Chloride Channels; Down-Regulation; Glucocorticoids; Interferon-gamma; Int | 2007 |
Effects of septic shock on renal function in humans.
Topics: Aged; Chlorides; Creatine; Female; Glycosuria; Humans; Kidney; Kidney Function Tests; Male; Middle A | 1967 |
Influence of Edwardsiella ictaluri septicemia on nitrite-induced methemoglobinemia in channel catfish (Ictalurus punctatus).
Topics: Animals; Chlorides; Enterobacteriaceae Infections; Erythrocyte Count; Fish Diseases; Fishes; Hematoc | 1984 |
Characterization of a mouse model for thrombomodulin deficiency.
Topics: Animals; Blood Coagulation; Carotid Artery Thrombosis; Chlorides; Cytokines; Ferric Compounds; Fibri | 2001 |
Sequential changes in body composition during infection: electron probe study IV.
Topics: Animals; Body Composition; Chickenpox; Child, Preschool; Chlorides; Electron Probe Microanalysis; Ha | 1977 |
[Alkalosis-chloridorrhea caused by anaerobic bacterial sepsis].
Topics: Alkalosis; Bacterial Infections; Chlorides; Clostridium Infections; Dehydration; Diarrhea, Infantile | 1977 |
Reduction of mortality and morbidity associated with pelvic exenteration.
Topics: Acidosis; Adolescent; Adult; Aged; Arteries; Chlorides; Hemorrhage; Humans; Infant; Ligation; Liver | 1975 |
Fluid and ion redistribution in skeletal muscle in an animal sepsis model.
Topics: Animals; Body Fluids; Chlorides; Disease Models, Animal; Electrolytes; Extracellular Space; Hyponatr | 1990 |
Assessment of the early cellular membrane response to live Escherichia coli bacteremia.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Output; Cell Membrane; Cell Membrane Permea | 1989 |
[Iron uptake of Salmonella typhimurium strains from different epidemiological sources].
Topics: Chlorides; Culture Media; Ferric Compounds; Gastroenteritis; Humans; Iron; Iron Radioisotopes; Salmo | 1985 |
A subdivision of Staphylococcus aureus strains belonging to the 83A, 84, 85, 6557, 592 complex with special reference to antibiotic resistance.
Topics: Anti-Bacterial Agents; Bacteriophage Typing; Chlorides; Cross Infection; Drug Resistance, Microbial; | 1971 |
Effect of milk formulae on acid balance.
Topics: Absorption; Acid-Base Equilibrium; Acidosis; Animals; Blood Urea Nitrogen; Calcium; Carbon Dioxide; | 1974 |
The site and characteristics of intestinal water and electrolyte loss in Escherichia coli-induced diarrhoea in calves.
Topics: Animals; Animals, Newborn; Bicarbonates; Catheterization; Cattle; Cattle Diseases; Chlorides; Colon; | 1974 |
Pathophysiology of anthrax.
Topics: Animals; Anthrax; Blood Cell Count; Blood Chemical Analysis; Blood Gas Analysis; Calcium; Chlorides; | 1966 |