Page last updated: 2024-08-23

etomidate and Sepsis

etomidate has been researched along with Sepsis in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (15.56)	29.6817
2010's	32 (71.11)	24.3611
2020's	6 (13.33)	2.80

Authors

Authors	Studies
Chakorn, T; Limsuwat, C; Pansiritanachot, W; Ruangsomboon, O	1
Faine, B; Mohr, NM	1
Fox, PE; Liang, L; Matchett, G; Moon, TS; Stewart, JW	1
Joo, JD; Jung, HS; Kim, YS; Lee, JY; Park, H; Park, YJ; Seo, KH	1
Amnuaypattanapon, K; Bumrungphanithaworn, A; Daorattanachai, K; Dasanadeba, I; Diskumpon, N; Imsuwan, I; Limjindaporn, C; Pornpachara, V; Pornpanit, C; Siripakarn, Y; Srivilaithon, W; Ueamsaranworakul, T	1
Brown, CA; Kaji, AH; Mohr, NM; Pape, SG; Runde, D; Walls, RM	1
Liu, C; Lv, L; Wang, T; Wei, P; Yang, Z	1
Chen, J; Jiang, J; Liu, J; Wang, B; Yang, J; Zhang, W; Zhu, Z	1
Devlin, RJ; Kalil, D	1
Bouillon, B; Gäßler, M; Lefering, R; Ruppert, M; Wafaisade, A	1
Coursin, DB; Fish, JT; Joffe, AM	1
Hunter, BR; Kirschner, J	1
Jones, AE; Puskarich, MA; Sterling, SA	1
Chan, CM; Mitchell, AL; Shorr, AF	2
Bernhard, M; Böttiger, BW; van den Heuvel, I; Wurmb, TE	1
Basciani, RM; Eberle, B; Erdoes, G	1
Alday, NJ; Doepker, BA; Jones, GM; Kimmons, LA; McCallister, JW; Phillips, GS	1
Li, R; Lv, S; Wang, Z; Xiong, JY; Zhang, Y; Zhu, J	1
Gu, WJ; Liu, JC; Tang, L; Wang, F	1
Li, RM; Liu, N; Shen, L; Wang, C; Xiong, JY; Zhang, Y	1
Chao, W; Feng, Y; Pejo, E; Raines, DE; Santer, P	1
Liu, N; Liu, S; Lv, S; Xiong, JY; Zhang, Y; Zhu, J	1
Abubaih, A; Weissman, C	1
Li, RM; Liu, N; Lv, S; Wang, C; Xiong, JY; Zhang, Y	1
Ali, NA; Cape, KM; Doepker, BA; Exline, MC; Phillips, G; Ryder, LP; Van Berkel, MA	1
Dean, P	1
Foëx, BA; Thomson, HE	1
Kulstad, EB; Rzechula, KH; Sweis, RT; Tekwani, KL; Watts, HF	2
Andrade, FM	1
Dmello, D; Matuschak, GM; O'Brien, J; Taylor, S	1
Jones, AE	1
Dagal, A; Dooney, NM	1
Ehrman, R; Ellis, T; Hayward, A; Lomax, A; Marcelin, J; Mullen, M; Przyklenk, K; Volturo, G; Wira, C	1
Bass, PA; Feldman, J	1
Al-Dorzi, HM; Arabi, YM; Cherfan, AJ; Kenny, LP	1
Beishuizen, A; Bijkerk, RM; de Jong, MF; Girbes, AR; Groeneveld, AB; Hempen, CM; Molenaar, N; van der Sluijs Veer, G; Vermes, I	1
Brown, M; Daniel, S; Deem, S; Keech, K; Sunshine, JE; Treggiari, MM; Weiss, NS; Yanez, ND	1
McKeown, DW; Ray, DC	1
Lauzier, F; Turgeon, AF	1
Badawi, O; Franey, C; Fraser, GL; Lerwick, PA; McPhee, LC; Riker, RR; Seder, DB; Zuckerman, IH	1
Kamp, R; Kress, JP	1
Césaréo, E; Dékadjévi, H; Tazarourte, K	1
Fengler, BT	1

Reviews

9 review(s) available for etomidate and Sepsis

Article	Year
Etomidate as an Induction Agent in Sepsis. Critical care nursing clinics of North America, 2018, Volume: 30, Issue:3 Topics: Adrenal Insufficiency; Anesthetics, Intravenous; Critical Illness; Etomidate; Humans; Sepsis	2018
In patients with severe sepsis, does a single dose of etomidate to facilitate intubation increase mortality? Annals of emergency medicine, 2013, Volume: 61, Issue:5 Topics: Etomidate; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Sepsis	2013
Pros and cons of etomidate--more discussion than evidence? Current opinion in anaesthesiology, 2013, Volume: 26, Issue:4 Topics: Etomidate; Hemodynamics; Humans; Hydrocortisone; Hypnotics and Sedatives; Sepsis	2013
Etomidate--a review of robust evidence for its use in various clinical scenarios. Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:4 Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Cardiovascular Diseases; Conscious Sedation; Etomidate; Humans; Hypnotics and Sedatives; Hypotension; Risk Assessment; Sepsis	2014
Single-dose etomidate does not increase mortality in patients with sepsis: a systematic review and meta-analysis of randomized controlled trials and observational studies. Chest, 2015, Volume: 147, Issue:2 Topics: Adult; Anesthetics, Intravenous; Etomidate; Humans; Intubation, Intratracheal; Observational Studies as Topic; Randomized Controlled Trials as Topic; Sepsis	2015
Anesthesia for Patients with Concomitant Sepsis and Cardiac Dysfunction. Anesthesiology clinics, 2016, Volume: 34, Issue:4 Topics: Anesthesia; Blood Glucose; Etomidate; Extracorporeal Membrane Oxygenation; Heart Diseases; Humans; Natriuretic Peptide, Brain; Sepsis	2016
Advantages and disadvantages of etomidate use for intubation of patients with sepsis. Pharmacotherapy, 2012, Volume: 32, Issue:5 Topics: Adrenal Insufficiency; Clinical Trials as Topic; Etomidate; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Sepsis; Treatment Outcome	2012
Etomidate for critically ill patients. Pro: yes we can use it. European journal of anaesthesiology, 2012, Volume: 29, Issue:11 Topics: Adrenal Insufficiency; Anesthetics, Intravenous; Critical Illness; Etomidate; Humans; Hypotension; Sepsis; Severity of Illness Index	2012
Etomidate is associated with mortality and adrenal insufficiency in sepsis: a meta-analysis. Critical care medicine, 2012, Volume: 40, Issue:11* Topics: Adrenal Insufficiency; Aged; Aged, 80 and over; Anesthetics, Intravenous; Etomidate; Female; Humans; Male; Middle Aged; Qualitative Research; Randomized Controlled Trials as Topic; Sepsis	2012

Trials

2 trial(s) available for etomidate and Sepsis

Article	Year
Clinical outcomes after a single induction dose of etomidate versus ketamine for emergency department sepsis intubation: a randomized controlled trial. Scientific reports, 2023, 04-19, Volume: 13, Issue:1 Topics: Adolescent; Adult; Anesthetics, Intravenous; Emergency Service, Hospital; Etomidate; Humans; Intubation, Intratracheal; Ketamine; Sepsis; Single-Blind Method; Vasoconstrictor Agents	2023
A comparison of the effects of etomidate and midazolam on hospital length of stay in patients with suspected sepsis: a prospective, randomized study. Annals of emergency medicine, 2010, Volume: 56, Issue:5 Topics: Aged; Aged, 80 and over; Double-Blind Method; Etomidate; Female; Humans; Hypnotics and Sedatives; Injections, Intravenous; Intubation, Intratracheal; Kaplan-Meier Estimate; Length of Stay; Male; Midazolam; Middle Aged; Sepsis; Time Factors; Treatment Outcome	2010

Article

Year

Clinical outcomes after a single induction dose of etomidate versus ketamine for emergency department sepsis intubation: a randomized controlled trial.

Scientific reports, 2023, 04-19, Volume: 13, Issue:1

Topics: Adolescent; Adult; Anesthetics, Intravenous; Emergency Service, Hospital; Etomidate; Humans; Intubation, Intratracheal; Ketamine; Sepsis; Single-Blind Method; Vasoconstrictor Agents

2023

A comparison of the effects of etomidate and midazolam on hospital length of stay in patients with suspected sepsis: a prospective, randomized study.

Annals of emergency medicine, 2010, Volume: 56, Issue:5

Topics: Aged; Aged, 80 and over; Double-Blind Method; Etomidate; Female; Humans; Hypnotics and Sedatives; Injections, Intravenous; Intubation, Intratracheal; Kaplan-Meier Estimate; Length of Stay; Male; Midazolam; Middle Aged; Sepsis; Time Factors; Treatment Outcome

2010

Other Studies

34 other study(ies) available for etomidate and Sepsis

Article	Year
Independent risk factors of mortality in patients with sepsis receiving single-dose etomidate as an induction agent during rapid sequence intubation in a large tertiary emergency department in Thailand. BMC emergency medicine, 2022, 06-03, Volume: 22, Issue:1 Topics: Emergency Service, Hospital; Etomidate; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Lactates; Lung Diseases; Rapid Sequence Induction and Intubation; Retrospective Studies; Risk Factors; Sepsis; Thailand	2022
Etomidate for endotracheal intubation in sepsis. Intensive care medicine, 2023, Volume: 49, Issue:3 Topics: Anesthetics, Intravenous; Etomidate; Humans; Intubation, Intratracheal; Ketamine; Sepsis	2023
Etomidate for endotracheal intubation in sepsis. Author's reply. Intensive care medicine, 2023, Volume: 49, Issue:3 Topics: Anesthetics, Intravenous; Etomidate; Humans; Intubation, Intratracheal; Sepsis	2023
The effects of etomidate on expression of high mobility group box 1 via the nuclear factor kappa B pathway in rat model of sepsis. The Libyan journal of medicine, 2023, Volume: 18, Issue:1 Topics: Animals; Cytokines; Etomidate; HMGB1 Protein; Interleukin-6; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Sepsis	2023
Etomidate Use Is Associated With Less Hypotension Than Ketamine for Emergency Department Sepsis Intubations: A NEAR Cohort Study. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2020, Volume: 27, Issue:11 Topics: Cohort Studies; Emergency Service, Hospital; Etomidate; Humans; Hypotension; Intubation, Intratracheal; Ketamine; Prospective Studies; Registries; Sepsis	2020
The inhibiting effect of intravenous anesthesia on adrenal gland functions under the sepsis condition. International journal of immunopathology and pharmacology, 2017, Volume: 30, Issue:2 Topics: Adrenal Glands; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Apoptosis; Etomidate; Female; Lung; Rats, Sprague-Dawley; Sepsis; Tumor Necrosis Factor-alpha	2017
Pharmacologic studies on ET-26 hydrochloride in a rat model of lipopolysaccharide-induced sepsis. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Nov-15, Volume: 109 Topics: Animals; Corticosterone; Cytokines; Etomidate; Female; Hypnotics and Sedatives; Kidney; Lipopolysaccharides; Lung; Male; Rats; Rats, Sprague-Dawley; Sepsis	2017
Pre-hospital emergent intubation in trauma patients: the influence of etomidate on mortality, morbidity and healthcare resource utilization. Scandinavian journal of trauma, resuscitation and emergency medicine, 2019, Jun-07, Volume: 27, Issue:1 Topics: Adult; Emergency Medical Services; Etomidate; Female; Health Resources; Hemodynamics; Hospital Mortality; Hospitalization; Humans; Intubation, Intratracheal; Length of Stay; Male; Middle Aged; Morbidity; Retrospective Studies; Sepsis	2019
Etomidate-trusted alternative time to trust alternatives? Critical care medicine, 2013, Volume: 41, Issue:3 Topics: Etomidate; Female; Hospital Information Systems; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Sepsis	2013
The effect of etomidate on mortality in sepsis remains unclear. Critical care medicine, 2013, Volume: 41, Issue:6 Topics: Adrenal Insufficiency; Anesthetics, Intravenous; Etomidate; Female; Humans; Male; Sepsis	2013
The authors reply. Critical care medicine, 2013, Volume: 41, Issue:6 Topics: Adrenal Insufficiency; Anesthetics, Intravenous; Etomidate; Female; Humans; Male; Sepsis	2013
Effects of etomidate on vasopressor use in patients with sepsis or severe sepsis: a propensity-matched analysis. Journal of critical care, 2014, Volume: 29, Issue:4 Topics: Adrenal Glands; Adult; Aged; Anesthetics, Intravenous; Case-Control Studies; Cohort Studies; Etomidate; Female; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Propensity Score; Retrospective Studies; Sepsis; Vasoconstrictor Agents	2014
Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency. The Journal of surgical research, 2015, Volume: 193, Issue:1 Topics: Adrenal Glands; Adrenal Insufficiency; Animals; Apoptosis; Cecum; Disease Models, Animal; Dose-Response Relationship, Drug; Etomidate; Female; Hypnotics and Sedatives; Inflammation; Ligation; NF-kappa B; Rats, Sprague-Dawley; Sepsis; Steroids; Wounds, Stab	2015
Effects of propofol and etomidate pretreatment on glucocorticoid receptor expression following induction of sepsis in rats. Genetics and molecular research : GMR, 2015, May-11, Volume: 14, Issue:2 Topics: Adrenal Cortex; Animals; Etomidate; Female; Inflammation; Propofol; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Sepsis; Survival Analysis	2015
Cyclopropyl-methoxycarbonyl Metomidate: Studies in a Lipopolysaccharide Inflammatory Model of Sepsis. Anesthesiology, 2015, Volume: 123, Issue:2 Topics: Animals; Disease Models, Animal; Etomidate; Inflammation; Inflammation Mediators; Infusions, Intravenous; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Sepsis	2015
The pituitary adenylate cyclase-activating polypeptide (PACAP) protects adrenal function in septic rats administered etomidate. Neuropeptides, 2016, Volume: 58 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Anesthetics, Intravenous; Animals; Apoptosis; Corticosterone; Etomidate; Female; Interferon-gamma; Ligation; Lymphocytes; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Sepsis; T-Lymphocytes; Toll-Like Receptor 4	2016
Etomidate inhibits nuclear factor-κB through decreased expression of glucocorticoid receptor in septic rats. Molecular medicine reports, 2016, Volume: 14, Issue:6 Topics: Anesthetics, Intravenous; Animals; Apoptosis; Biomarkers; Cytokines; Disease Models, Animal; Etomidate; Female; Gene Expression Regulation; Inflammation Mediators; Lymphocytes; NF-kappa B; Rats; Receptors, Glucocorticoid; Sepsis	2016
Increased incidence of clinical hypotension with etomidate compared to ketamine for intubation in septic patients: A propensity matched analysis. Journal of critical care, 2017, Volume: 38 Topics: Anesthetics, Intravenous; Cohort Studies; Critical Care; Critical Illness; Etomidate; Female; Humans; Hypotension; Incidence; Intensive Care Units; Intubation, Intratracheal; Ketamine; Male; Middle Aged; Ohio; Propensity Score; Retrospective Studies; Sepsis	2017
Should etomidate be used for rapid-sequence intubation induction in critically ill septic patients? Probably not. The American journal of emergency medicine, 2008, Volume: 26, Issue:6 Topics: Anesthetics, Intravenous; Critical Illness; Etomidate; Humans; Intubation, Intratracheal; Sepsis	2008
Steroids in sepsis, etomidate and Pearl Harbor. Emergency medicine journal : EMJ, 2008, Volume: 25, Issue:8 Topics: Anesthetics, Intravenous; Anti-Inflammatory Agents; Etomidate; History, 20th Century; Humans; Hydrocortisone; Naval Medicine; Randomized Controlled Trials as Topic; Sepsis; Superinfection; World War II	2008
A prospective observational study of the effect of etomidate on septic patient mortality and length of stay. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:1 Topics: Aged; Aged, 80 and over; Anesthetics, Intravenous; Conscious Sedation; Etomidate; Hospital Mortality; Humans; Intubation, Intratracheal; Length of Stay; Linear Models; Observation; Prospective Studies; Sepsis	2009
Letter to the editor: Hypotension after etomidate use in sepsis. Journal of Korean medical science, 2009, Volume: 24, Issue:6 Topics: Adrenal Insufficiency; Etomidate; Hypnotics and Sedatives; Hypotension; Randomized Controlled Trials as Topic; Sepsis; Steroids	2009
Outcomes of etomidate in severe sepsis and septic shock. Chest, 2010, Volume: 138, Issue:6 Topics: Academic Medical Centers; Aged; Aged, 80 and over; APACHE; Cohort Studies; Conscious Sedation; Critical Illness; Drug Administration Schedule; Etomidate; Female; Follow-Up Studies; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Intubation, Intratracheal; Logistic Models; Male; Middle Aged; Multivariate Analysis; Reference Values; Respiration, Artificial; Retrospective Studies; Risk Assessment; Sepsis; Shock, Septic; Survival Analysis; Treatment Outcome	2010
The etomidate debate. Annals of emergency medicine, 2010, Volume: 56, Issue:5 Topics: Etomidate; Humans; Hypnotics and Sedatives; Injections, Intravenous; Intubation, Intratracheal; Sepsis; Time Factors	2010
Etomidate for induction of the septic patient. British journal of anaesthesia, 2011, Volume: 106, Issue:3 Topics: Anesthetics, Intravenous; Etomidate; Humans; Perioperative Care; Sepsis	2011
Etomidate use in severe sepsis and septic shock patients does not contribute to mortality. Internal and emergency medicine, 2011, Volume: 6, Issue:3 Topics: Etomidate; Female; Humans; Male; Middle Aged; Retrospective Studies; Sepsis; Shock, Septic	2011
Etomidate, sepsis, and informed consent. Annals of emergency medicine, 2011, Volume: 57, Issue:6 Topics: Etomidate; Humans; Informed Consent; Intubation, Intratracheal; Randomized Controlled Trials as Topic; Sepsis	2011
Steroidogenesis in the adrenal dysfunction of critical illness: impact of etomidate. Critical care (London, England), 2012, Jul-10, Volume: 16, Issue:4 Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Aged; Critical Illness; Etomidate; Female; Hospitals, University; Humans; Hydrocortisone; Hypnotics and Sedatives; Intensive Care Units; Male; Netherlands; Prospective Studies; Sepsis	2012
Etomidate, adrenal function, and mortality in critically ill patients. Respiratory care, 2013, Volume: 58, Issue:4 Topics: Adrenal Insufficiency; Adult; Aged; Critical Illness; Etomidate; Female; Hospital Mortality; Humans; Hypnotics and Sedatives; Male; Middle Aged; Respiration, Artificial; Retrospective Studies; Risk Assessment; Sepsis	2013
Etomidate: buy now, pay later?. Critical care medicine, 2012, Volume: 40, Issue:11* Topics: Adrenal Insufficiency; Anesthetics, Intravenous; Etomidate; Female; Humans; Male; Sepsis	2012
Single-dose etomidate is not associated with increased mortality in ICU patients with sepsis: analysis of a large electronic ICU database. Critical care medicine, 2013, Volume: 41, Issue:3 Topics: Adult; Aged; Confidence Intervals; Dose-Response Relationship, Drug; Etomidate; Female; Hospital Information Systems; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Intubation, Intratracheal; Length of Stay; Male; Middle Aged; Proportional Hazards Models; Retrospective Studies; Sepsis; Severity of Illness Index; United States	2013
Etomidate, sepsis, and adrenal function: not as bad as we thought? Critical care (London, England), 2007, Volume: 11, Issue:3 Topics: Adrenal Cortex Hormones; Adrenal Glands; Anesthetics, Intravenous; Critical Illness; Etomidate; Humans; Hydrocortisone; Sepsis; Treatment Outcome	2007
[Etomidate and sepsis: an accusation without proof, a proceeding with no victim]. Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:12 Topics: Etomidate; Humans; Hypnotics and Sedatives; Sepsis	2007
Should etomidate be used for rapid-sequence intubation induction in critically ill septic patients? The American journal of emergency medicine, 2008, Volume: 26, Issue:2 Topics: Anesthetics, Intravenous; Critical Illness; Etomidate; Humans; Intubation, Intratracheal; Sepsis	2008