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9-(2-hydroxy-3-nonyl)adenine and Sepsis

9-(2-hydroxy-3-nonyl)adenine has been researched along with Sepsis in 2 studies

9-(2-hydroxy-3-nonyl)adenine: specific inhibitor of adenosine deaminase

Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to verify the hypothesis that adenosine deaminase-1 and cyclic guanosine monophosphate-stimulated phosphodiesterase inhibition by erythro-9-[2-hydroxyl-3-nonyl]-adenine could be beneficial in experimental endotoxicosis/sepsis."7.74The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation. ( Bardenheuer, H; Conzelmann, LO; Funke, B; Hofer, S; Kayhan, N; Schmidt, H; Steppan, J; Vahl, CF; Weigand, MA; Winkler, H, 2008)
" The aim of this study was to verify the hypothesis that adenosine deaminase-1 and cyclic guanosine monophosphate-stimulated phosphodiesterase inhibition by erythro-9-[2-hydroxyl-3-nonyl]-adenine could be beneficial in experimental endotoxicosis/sepsis."3.74The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation. ( Bardenheuer, H; Conzelmann, LO; Funke, B; Hofer, S; Kayhan, N; Schmidt, H; Steppan, J; Vahl, CF; Weigand, MA; Winkler, H, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kayhan, N1
Funke, B1
Conzelmann, LO1
Winkler, H1
Hofer, S1
Steppan, J1
Schmidt, H1
Bardenheuer, H1
Vahl, CF1
Weigand, MA1
Conlon, BA1
Law, WR1

Other Studies

2 other studies available for 9-(2-hydroxy-3-nonyl)adenine and Sepsis

ArticleYear
The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation.
    Critical care (London, England), 2008, Volume: 12, Issue:5

    Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Female; Intestinal Absorption

2008
Macrophages are a source of extracellular adenosine deaminase-2 during inflammatory responses.
    Clinical and experimental immunology, 2004, Volume: 138, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Adenine; Adenosine Deaminase; Animals; Cells, Cultured; DNA-Bi

2004