beta-lapachone has been researched along with Sepsis in 2 studies
beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase
beta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sepsis is characterized by a dysregulated immune response to infection characterized by an early hyperinflammatory and oxidative response followed by a subsequent immunosuppression phase." | 1.56 | ( de A Pontes, ACA; de B Oliveira, AL; de Oliveira, AB; de Oliveira, JP; Dorneles, GP; Dos Santos, SM; Júnior, LCR; Monteiro, MC; Monteiro, VVS; Navegantes-Lima, KC; Quadros, LBG; Romão, PRT, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| de B Oliveira, AL | 1 |
| Navegantes-Lima, KC | 1 |
| Monteiro, VVS | 1 |
| Quadros, LBG | 1 |
| de Oliveira, JP | 1 |
| Dos Santos, SM | 1 |
| de A Pontes, ACA | 1 |
| Dorneles, GP | 1 |
| Romão, PRT | 1 |
| Júnior, LCR | 1 |
| de Oliveira, AB | 1 |
| Monteiro, MC | 1 |
| Tzeng, HP | 1 |
| Ho, FM | 1 |
| Chao, KF | 1 |
| Kuo, ML | 1 |
| Lin-Shiau, SY | 1 |
| Liu, SH | 1 |
2 other studies available for beta-lapachone and Sepsis
| Article | Year |
|---|---|
Topics: Animals; Anti-Inflammatory Agents; Chemoprevention; Cytokines; Disease Models, Animal; Immunosuppres | 2020 |
beta-Lapachone reduces endotoxin-induced macrophage activation and lung edema and mortality.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinica | 2003 |