Page last updated: 2024-10-22

amlodipine and Sepsis

amlodipine has been researched along with Sepsis in 2 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

Research Excerpts

ExcerptRelevanceReference
" The purpose of the present study was to evaluate therapeutic effect and possible mechanism of action of amlodipine, one of the widely used CCBs, on rat cardiac dysfunction during sepsis induced by lipopolysaccharide (LPS)."3.75Amlodipine inhibits TNF-alpha production and attenuates cardiac dysfunction induced by lipopolysaccharide involving PI3K/Akt pathway. ( Cao, W; Hao, LL; Li, T; Li, XQ; Mei, QB; Zeng, AG; Zhang, XN, 2009)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, XQ1
Cao, W1
Li, T1
Zeng, AG1
Hao, LL1
Zhang, XN1
Mei, QB1
Sarullo, FM1
Americo, L1
Accardo, S1
Cicero, S1
Schicchi, R1
SchirĂ², M1
Castello, A1

Other Studies

2 other studies available for amlodipine and Sepsis

ArticleYear
Amlodipine inhibits TNF-alpha production and attenuates cardiac dysfunction induced by lipopolysaccharide involving PI3K/Akt pathway.
    International immunopharmacology, 2009, Volume: 9, Issue:9

    Topics: Amlodipine; Animals; Anti-Inflammatory Agents; Calcium Channel Blockers; Cells, Cultured; Gene Expre

2009
Tako-tsubo cardiomyopathy observed in a patient with sepsis and transient hyperthyroidism.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2009, Volume: 72, Issue:1

    Topics: Amlodipine; Anti-Bacterial Agents; Antihypertensive Agents; Antithyroid Agents; Aspirin; Echocardiog

2009