distigmine has been researched along with Sepsis in 1 studies
distigmine : A carbamate ester resulting from the formal condensation of both carboxy groups of hexane-1,6-diylbis(methylcarbamic acid) with the hydroxy group of 3-hydroxy-1-methylpyridinium.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cholinesterase inhibitor distigmine inhibited induction of inflammatory cytokines and catecholamines as well as HRV suppression in a rat CLP model, suggesting that an agent modulating the cholinergic anti-inflammatory pathway can control excess cytokine production involved in the pathogenesis of severe sepsis/septic shock." | 3.78 | Effects of a peripheral cholinesterase inhibitor on cytokine production and autonomic nervous activity in a rat model of sepsis. ( Hirayama, Y; Nakamura, M; Oda, S; Sadahiro, T; Setoguchi, D; Tateishi, Y; Watanabe, E; Yatsuki, H, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Setoguchi, D | 1 |
| Yatsuki, H | 1 |
| Sadahiro, T | 1 |
| Nakamura, M | 1 |
| Hirayama, Y | 1 |
| Watanabe, E | 1 |
| Tateishi, Y | 1 |
| Oda, S | 1 |
1 other study available for distigmine and Sepsis
| Article | Year |
|---|---|
Effects of a peripheral cholinesterase inhibitor on cytokine production and autonomic nervous activity in a rat model of sepsis.
Topics: Animals; Autonomic Nervous System; Catecholamines; Cholinesterase Inhibitors; Cytokines; Disease Mod | 2012 |