azathioprine has been researched along with Sepsis in 50 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 21-year-old woman with a history of systemic lupus erythematosus presented to the emergency department with acute-onset nausea, vomiting, and fevers." | 5.91 | Azathioprine-induced hypersensitivity reaction mimicking sepsis in a patient with systemic lupus erythematosus. ( Chao, Y; Kazi, S; McKenzie, PL; Pathak, S, 2023) |
| " Events included eight patients with malignancies, two with pancytopenia taking methotrexate, three with septic arthritis, and two with septicaemias." | 3.71 | Monitoring and assessing the safety of disease-modifying antirheumatic drugs: a West Midlands experience. ( Bevan, J; Homer, D; Jobanputra, P; Maggs, F, 2002) |
| "The effect of prodigiosan, levamisol and methyluracil on the process of experimental sepsis caused by Proteus was studied comparatively on mice, and the primary immune response was studied on intact animals treated with prednisolone, cyclophosphan or azathioprin." | 3.67 | [Effect of prodigiozan, levamisole and methyluracil on the course of an experimental infection and primary immune response]. ( Lazareva, DN; Riabchinskaia, LA, 1986) |
| "Pulmonary infections were less common in cyclosporine-treated renal patients than in Aza-treated patients (P less than 0." | 2.65 | Early infections in kidney, heart, and liver transplant recipients on cyclosporine. ( Dummer, JS; Hardy, A; Ho, M; Poorsattar, A, 1983) |
| "A 21-year-old woman with a history of systemic lupus erythematosus presented to the emergency department with acute-onset nausea, vomiting, and fevers." | 1.91 | Azathioprine-induced hypersensitivity reaction mimicking sepsis in a patient with systemic lupus erythematosus. ( Chao, Y; Kazi, S; McKenzie, PL; Pathak, S, 2023) |
| "Azathioprine 50 mg orally was then used in place of dapsone due to rapid disease progression with extensive skin involvement." | 1.91 | Rescue treatment with intravenous immunoglobulin and amniotic membrane dressing in refractory paediatric pemphigus vulgaris with sepsis. ( Akham, R; Bhatia, R; Hazarika, N; Paonam, R, 2023) |
| "LON was not observed in minimal change disease or focal segmental glomerulosclerosis." | 1.62 | Incidence, Clinical Features, and Outcomes of Late-Onset Neutropenia From Rituximab for Autoimmune Disease. ( Cortazar, FB; Huizenga, NR; Laliberte, K; Niles, JL; Rhee, EP; Rosenthal, JM; Wallace, ZS; Zonozi, R, 2021) |
| "Treatment with prednisone and azathioprine, plus, in three children, cyclosporine, resulted in complete remission in eight, partial remission in six, and failure in two." | 1.37 | Giant cell hepatitis with autoimmune hemolytic anemia in early childhood: long-term outcome in 16 children. ( Bernard, O; Choulot, JJ; Fabre, M; Gori, L; Jacquemin, E; Maggiore, G; Pacifico, L; Resti, M; Sciveres, M, 2011) |
| "Early sepsis was seen in 58 patients (17." | 1.34 | The impact of preoperative immunomodulation on pouch-related septic complications after ileal pouch-anal anastomosis. ( Abdulgader, A; Burke, D; Lim, M; Sagar, P; Thekkinkattil, D, 2007) |
| "Five developed septic arthritis, including the site of a hip prosthesis in one patient." | 1.28 | Salmonella arizona arthritis and septicemia associated with rattlesnake ingestion by patients with connective tissue diseases. A dangerous complication of folk medicine. ( Alarcón-Segovia, D; Guerra-Bautista, G; Kraus, A, 1991) |
| "Bacterial sepsis was identified and treated twice during follow-up, viral infections on five occasions, and fungal infection once." | 1.28 | Rejection and infection after pediatric cardiac transplantation. ( Bolman, RM; Braunlin, EA; Canter, CE; Olivari, MT; Ring, WS; Spray, TL, 1990) |
| "There were no deaths due to infection during the 10-month study period." | 1.26 | Oral infection in immunosuppressed renal transplant patients. ( Cohen, G; Greenberg, MS, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (60.00) | 18.7374 |
| 1990's | 5 (10.00) | 18.2507 |
| 2000's | 7 (14.00) | 29.6817 |
| 2010's | 5 (10.00) | 24.3611 |
| 2020's | 3 (6.00) | 2.80 |
| Authors | Studies |
|---|---|
| McKenzie, PL | 1 |
| Chao, Y | 1 |
| Pathak, S | 1 |
| Kazi, S | 1 |
| Akham, R | 1 |
| Bhatia, R | 1 |
| Paonam, R | 1 |
| Hazarika, N | 1 |
| Zonozi, R | 1 |
| Wallace, ZS | 1 |
| Laliberte, K | 1 |
| Huizenga, NR | 1 |
| Rosenthal, JM | 1 |
| Rhee, EP | 1 |
| Cortazar, FB | 1 |
| Niles, JL | 1 |
| Panda, BK | 1 |
| Umarje, S | 1 |
| Diwan, A | 1 |
| Siripaitoon, B | 1 |
| Lertwises, S | 1 |
| Uea-Areewongsa, P | 1 |
| Khwannimit, B | 1 |
| Hsu, WY | 1 |
| Chiou, SS | 1 |
| Liao, YM | 1 |
| Shu, HL | 1 |
| Zeng, YS | 1 |
| Wong, CC | 1 |
| Lin, PC | 1 |
| Afzali, A | 1 |
| Park, CJ | 1 |
| Zhu, K | 1 |
| Hu, JK | 1 |
| Sharma, P | 1 |
| Sinanan, MN | 1 |
| Lee, SD | 1 |
| Maggiore, G | 1 |
| Sciveres, M | 1 |
| Fabre, M | 1 |
| Gori, L | 1 |
| Pacifico, L | 1 |
| Resti, M | 1 |
| Choulot, JJ | 1 |
| Jacquemin, E | 1 |
| Bernard, O | 1 |
| Jobanputra, P | 1 |
| Maggs, F | 1 |
| Homer, D | 1 |
| Bevan, J | 1 |
| Matzkies, FG | 1 |
| Manger, B | 1 |
| Schmitt-Haendle, M | 1 |
| Nagel, T | 1 |
| Kraetsch, HG | 1 |
| Kalden, JR | 1 |
| Schulze-Koops, H | 1 |
| RIFKIND, D | 1 |
| MARCHIORO, TL | 1 |
| WADDELL, WR | 1 |
| STARZL, TE | 3 |
| DOSSETOR, JB | 1 |
| GAULT, MH | 1 |
| OLIVER, JA | 1 |
| INGLIS, FG | 1 |
| MACKINNON, KJ | 1 |
| MACLEAN, LD | 1 |
| ROENIGK, HH | 1 |
| HASERICK, JR | 1 |
| NAKAMOTO, S | 2 |
| MCCORMACK, LJ | 1 |
| STRAFFON, RA | 1 |
| KOLFF, WJ | 1 |
| Joss, N | 1 |
| Rodger, RS | 1 |
| McMillan, MA | 1 |
| Junor, BJ | 1 |
| Lim, M | 1 |
| Sagar, P | 1 |
| Abdulgader, A | 1 |
| Thekkinkattil, D | 1 |
| Burke, D | 1 |
| Hagenah, GC | 1 |
| Wündisch, T | 1 |
| Eckstein, E | 1 |
| Zimmermann, S | 1 |
| Holst, F | 1 |
| Grimm, W | 1 |
| Neubauer, A | 1 |
| Lohoff, M | 1 |
| Richard, VS | 1 |
| Al-Ismail, D | 1 |
| Salamat, A | 1 |
| Dummer, JS | 1 |
| Hardy, A | 1 |
| Poorsattar, A | 1 |
| Ho, M | 1 |
| König, P | 1 |
| Steiner, E | 1 |
| Margreiter, R | 1 |
| Dittrich, P | 1 |
| Theodor, E | 1 |
| Niv, Y | 1 |
| Bat, L | 1 |
| Bell, WR | 1 |
| Langrehr, JM | 2 |
| Glanemann, M | 1 |
| Guckelberger, O | 1 |
| Klupp, J | 2 |
| Neumann, U | 1 |
| Machens, C | 1 |
| Lohmann, R | 1 |
| Knoop, M | 1 |
| Lobeck, H | 1 |
| Schlag, H | 1 |
| Keck, H | 1 |
| Settmacher, U | 1 |
| Bechstein, WO | 2 |
| Neuhaus, PJ | 1 |
| Stratton, JD | 1 |
| Farrington, K | 1 |
| Junge, G | 1 |
| Jonas, S | 1 |
| Neuhaus, R | 1 |
| Neuhaus, P | 1 |
| Mozes, MF | 1 |
| Ascher, NL | 1 |
| Balfour, HH | 1 |
| Simmons, RL | 2 |
| Najarian, JS | 2 |
| Greenberg, MS | 1 |
| Cohen, G | 1 |
| Friedman, EA | 1 |
| Beyer, MM | 1 |
| Delmonico, FL | 1 |
| Cosimi, AB | 1 |
| Russell, PS | 1 |
| Kraus, A | 1 |
| Guerra-Bautista, G | 1 |
| Alarcón-Segovia, D | 1 |
| Braunlin, EA | 1 |
| Canter, CE | 1 |
| Olivari, MT | 1 |
| Ring, WS | 1 |
| Spray, TL | 1 |
| Bolman, RM | 1 |
| Riabchinskaia, LA | 1 |
| Lazareva, DN | 1 |
| Groth, CG | 2 |
| Brettschneider, L | 2 |
| Moon, JB | 1 |
| Fulginiti, VA | 2 |
| Cotton, EK | 1 |
| Porter, KA | 2 |
| Barnard, CN | 1 |
| Scribner, R | 1 |
| Putnam, CW | 1 |
| Gilbert, S | 1 |
| Swannell, AJ | 1 |
| Coomes, EN | 1 |
| Tallent, MB | 1 |
| Kjellstrand, CM | 1 |
| Myerowitz, RL | 1 |
| Medeiros, AA | 1 |
| O'Brien, TF | 1 |
| Williams, R | 1 |
| Smith, MG | 1 |
| Ku, G | 1 |
| Varghese, Z | 1 |
| Fernando, ON | 1 |
| Baillod, R | 1 |
| Hopewell, JP | 1 |
| Moorhead, JF | 1 |
| Cho, ES | 1 |
| Connolly, E | 1 |
| Porro, RS | 1 |
| Larrieu, AJ | 1 |
| Rodríguez, MS | 1 |
| Santiago Delpín, EA | 1 |
| Kondo, Y | 1 |
| Cockrell, JV | 1 |
| Kuwahara, O | 1 |
| Hardy, JD | 1 |
| Thiele, KG | 1 |
| Kelly, WD | 1 |
| Lillehei, RC | 1 |
| Aust, JB | 1 |
| Varco, RL | 1 |
| Leonard, AS | 1 |
| Griffin, WO | 1 |
| Markland, C | 1 |
| Herdman, RC | 1 |
| Vernier, RL | 1 |
| Michael, AF | 1 |
| Levitt, J | 1 |
| Eales, L | 1 |
| Grosser, Y | 1 |
| Levey, M | 1 |
| Stinson, EB | 1 |
| Bieber, CP | 1 |
| Griepp, RB | 1 |
| Clark, DA | 1 |
| Shumway, NE | 1 |
| Remington, JS | 1 |
| Tilney, NL | 1 |
| Murray, JE | 1 |
| Becker, K | 1 |
| Williams, RJ | 1 |
| Chandler, JG | 1 |
| Orloff, MJ | 1 |
1 review available for azathioprine and Sepsis
| Article | Year |
|---|---|
Preoperative Use of Methotrexate and the Risk of Early Postoperative Complications in Patients with Inflammatory Bowel Disease.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azathioprine; Colitis, Ulcerative; Crohn Dise | 2016 |
5 trials available for azathioprine and Sepsis
| Article | Year |
|---|---|
Randomized study comparing cyclosporine with azathioprine one year after renal transplantation-15-year outcome data.
Topics: Adult; Azathioprine; Cardiovascular Diseases; Cause of Death; Cyclosporine; Follow-Up Studies; Human | 2007 |
Early infections in kidney, heart, and liver transplant recipients on cyclosporine.
Topics: Adult; Azathioprine; Cyclosporins; Cytomegalovirus Infections; Female; Graft Survival; Heart Transpl | 1983 |
A randomized, placebo-controlled trial with anti-interleukin-2 receptor antibody for immunosuppressive induction therapy after liver transplantation.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibodies, Monoclonal; Azathioprine; Cholangitis; Cyclospor | 1998 |
Quadruple versus dual tacrolimus-based induction after liver transplantation: a prospective, randomized trial.
Topics: Antilymphocyte Serum; Azathioprine; Bacterial Infections; Cytomegalovirus Infections; Drug Therapy, | 2001 |
Infections in recipients of liver homografts.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Azathioprine; Candida; Cytomegalovirus; Enterobacter | 1968 |
44 other studies available for azathioprine and Sepsis
| Article | Year |
|---|---|
Azathioprine-induced hypersensitivity reaction mimicking sepsis in a patient with systemic lupus erythematosus.
Topics: Abdominal Pain; Adult; Azathioprine; Female; Humans; Immunosuppressive Agents; Lupus Erythematosus, | 2023 |
Rescue treatment with intravenous immunoglobulin and amniotic membrane dressing in refractory paediatric pemphigus vulgaris with sepsis.
Topics: Azathioprine; Biological Dressings; Child; Dapsone; Humans; Immunoglobulins, Intravenous; Pemphigus; | 2023 |
Incidence, Clinical Features, and Outcomes of Late-Onset Neutropenia From Rituximab for Autoimmune Disease.
Topics: Adult; Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Asymptomatic Diseases; Auto | 2021 |
Azathioprine-Induced Pancytopenia and Septic Complications: A Probable Cause of Death.
Topics: Azathioprine; Fatal Outcome; Humans; Immunosuppressive Agents; Male; Middle Aged; Pancytopenia; Seps | 2018 |
A study of Thai patients with systemic lupus erythematosus in the medical intensive care unit: epidemiology and predictors of mortality.
Topics: Adult; APACHE; Azathioprine; Female; Glucocorticoids; Hospital Mortality; Humans; Immunosuppressive | 2015 |
Successful management of multilineage autoimmune cytopenia complicated with severe infection and deep vein thrombosis in a patient with Hodgkin lymphoma post-autologous hematopoietic stem cell transplantation.
Topics: Adolescent; Autoimmune Diseases; Azathioprine; Bone Marrow Transplantation; Cell Lineage; Cyclophosp | 2016 |
Giant cell hepatitis with autoimmune hemolytic anemia in early childhood: long-term outcome in 16 children.
Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Bilirubin; Coom | 2011 |
Monitoring and assessing the safety of disease-modifying antirheumatic drugs: a West Midlands experience.
Topics: Antirheumatic Agents; Arthritis, Infectious; Azathioprine; Drug Monitoring; Humans; Hypokalemia; Lun | 2002 |
Severe septicaemia in a patient with polychondritis and Sweet's syndrome after initiation of treatment with infliximab.
Topics: Antibodies, Monoclonal; Azathioprine; Diabetes Mellitus, Type 1; Fatal Outcome; Humans; Immunosuppre | 2003 |
INFECTIOUS DISEASES ASSOCIATED WITH RENAL HOMOTRANSPLANTATION.
Topics: Adolescent; Agammaglobulinemia; Agranulocytosis; Azathioprine; Bacteriophage Typing; Child; Diagnosi | 1964 |
CADAVER RENAL HOMOTRANSPLANTS: INITIAL EXPERIENCES.
Topics: Azathioprine; Cadaver; Dactinomycin; Enzymes; Histoplasmosis; Humans; Imidazoles; Immunosuppressive | 1964 |
SYSTEMIC LUPUS ERYTHEMATOSUS AND RENAL TRANSPLANTATION: REPORT OF TWO CASES.
Topics: Adolescent; Azathioprine; Humans; Kidney; Kidney Transplantation; Kidneys, Artificial; Leukopenia; L | 1965 |
CLINICAL EXPERIENCE WITH RENAL TRANSPLANTATION.
Topics: Azathioprine; Cadaver; Dactinomycin; Drug Therapy; Hemorrhage; Humans; Hypertension; Immunosuppressi | 1965 |
The impact of preoperative immunomodulation on pouch-related septic complications after ileal pouch-anal anastomosis.
Topics: Adult; Anal Canal; Anastomosis, Surgical; Azathioprine; Colonic Diseases; Colonic Pouches; Cyclospor | 2007 |
[Sepsis-like disease in an immunocompromised patient with a travel history to Mallorca].
Topics: Adult; Animals; Azathioprine; Biopsy; Bone Marrow; Colectomy; Colitis, Ulcerative; Colon; Colonic Ne | 2007 |
Should we test TPMT enzyme levels before starting azathioprine?
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Bone Marrow Diseases; Diagnostic Tests, Routine; Female; | 2007 |
[The first 100 kidney transplants undertaken at the University of Innsbruck (author's transl)].
Topics: Adolescent; Adult; Austria; Azathioprine; Child; Cortisone; Female; Graft Rejection; History, 20th C | 1981 |
Imuran in the treatment of ulcerative colitis.
Topics: Adolescent; Adult; Aged; Azathioprine; Child; Colitis, Ulcerative; Drug Therapy, Combination; Female | 1981 |
Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome relapse: frequency, pathogenesis, and meaning.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Blood Transfusion; Female; Hematocrit; Hemoglobins; He | 1997 |
Relapse of vasculitis, sepsis, or azathioprine allergy?
Topics: Adult; Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Male; Re | 1998 |
Jaundice after renal allotransplantation.
Topics: Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Azathioprine; Bilirubin; Blood Transfusion | 1978 |
Oral infection in immunosuppressed renal transplant patients.
Topics: Adult; Azathioprine; Bacteria; Fungi; Humans; Immunosuppression Therapy; Infections; Kidney Transpla | 1977 |
Skin and renal rabbit allograft rejection following large pulse doses of methylprednisolone.
Topics: Animals; Azathioprine; Blood; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; G | 1975 |
Renal transplantation in the older age group.
Topics: Acute Kidney Injury; Age Factors; Aged; Azathioprine; Cadaver; Coronary Disease; Diabetes Complicati | 1975 |
Salmonella arizona arthritis and septicemia associated with rattlesnake ingestion by patients with connective tissue diseases. A dangerous complication of folk medicine.
Topics: Adolescent; Adult; Animals; Arthritis, Infectious; Azathioprine; Connective Tissue Diseases; Drug Th | 1991 |
Rejection and infection after pediatric cardiac transplantation.
Topics: Adolescent; Azathioprine; Bacterial Infections; Biopsy; Child; Child, Preschool; Cyclosporins; Femal | 1990 |
[Effect of prodigiozan, levamisole and methyluracil on the course of an experimental infection and primary immune response].
Topics: Animals; Antibody-Producing Cells; Azathioprine; Cyclophosphamide; Drug Evaluation, Preclinical; Fem | 1986 |
Extended survival in 3 cases of orthotopic homotransplantation of the human liver.
Topics: Acidosis; Azathioprine; Biliary Tract; Cadaver; Child, Preschool; Female; gamma-Globulins; Humans; I | 1968 |
Human heart transplantation.
Topics: Antibodies, Anti-Idiotypic; Azathioprine; Cardiac Catheterization; Cardiac Output; Cardiomegaly; Car | 1969 |
Preliminary results of azathioprine treatment in severe rheumatic disease.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Arthritis; Arthritis, Rheumatoid; Azathioprine; Blood Cell | 1969 |
Prevention of death after renal transplantation. I. Recognizable patterns leading to death in long-term survivors.
Topics: Adolescent; Adult; Azathioprine; Cadaver; Child; Death; Female; Graft vs Host Reaction; Humans; Infe | 1970 |
Bacterial infection in renal homotransplant recipients. A study of fifty-three bacteremic episodes.
Topics: Adult; Age Factors; Azathioprine; Bacterial Infections; Enterobacteriaceae Infections; Female; Graft | 1972 |
Liver transplantation: a clinical and immunological appraisal.
Topics: Adult; Animals; Autoantibodies; Azathioprine; Biliary Fistula; Cell Migration Inhibition; Complement | 1972 |
Serum IgG and renal transplantation.
Topics: Adult; Azathioprine; Creatinine; Escherichia coli Infections; Female; Graft Rejection; Hematocrit; H | 1973 |
Primary reticulum cell sarcoma of the brain in a renal transplantation recipient.
Topics: Abscess; Adult; Azathioprine; Brain Neoplasms; Chronic Disease; Epididymitis; Frontal Lobe; Glomerul | 1974 |
Results of the nitroblue tetrazolium test in experimental immunosuppression.
Topics: Animals; Azathioprine; Bacterial Infections; Dogs; Escherichia coli Infections; Immunosuppression Th | 1974 |
Histopathology of one-stage bilateral lung allografts.
Topics: Animals; Antilymphocyte Serum; Azathioprine; Bronchi; Dogs; Graft Rejection; Immunosuppression Thera | 1974 |
[Therapy of enteritis regional Crohn using azathioprine].
Topics: Abscess; Azathioprine; Crohn Disease; Humans; Pancreatitis; Prospective Studies; Sepsis | 1973 |
Kindey transplantation: experiences at the University of Minnesota Hospitals.
Topics: Adolescent; Adult; Antigens; Azathioprine; Cadaver; Child; Female; Humans; Ileostomy; Immune Toleran | 1967 |
Coproporphyrinuria and heart transplantation: its significance.
Topics: Age Factors; Anemia, Hemolytic; Azathioprine; Chemical and Drug Induced Liver Injury; Electrocardiog | 1970 |
Infectious complications after cardiac transplantation in man.
Topics: Adult; Amphotericin B; Antilymphocyte Serum; Azathioprine; Dactinomycin; Female; Heart Transplantati | 1971 |
Severe temporary deterioration of renal transplant function following meningococcemia.
Topics: Adolescent; Antigens; Antigens, Bacterial; Azathioprine; Child; Cross Reactions; Female; Graft Rejec | 1971 |
[Immunosuppressive therapy of chronic aggressive hepatitis].
Topics: Azathioprine; Chronic Disease; Cortisone; Cyclophosphamide; Female; Follow-Up Studies; Hepatitis; Hu | 1972 |
Candida septicemia.
Topics: Adolescent; Adult; Age Factors; Aged; Amphotericin B; Anti-Bacterial Agents; Autopsy; Azathioprine; | 1971 |