biguanides has been researched along with Sepsis in 8 studies
Biguanides: Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
biguanides : A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Sepsis: Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Secondary outcomes included: central line-associated infection; primary bloodstream infection; local infection; skin complications; device/dressing dwell time; serious adverse events, and cost-effectiveness." | 3.11 | Polyhexamethylene biguanide discs versus unmedicated dressings for prevention of central venous catheter-associated infection in the intensive care unit: A pilot randomised controlled trial to assess protocol safety and feasibility. ( Corley, A; Irvine, L; Larsen, E; Marsh, N; McGuinness, N; Pearse, I; Pelecanos, A; Rapchuk, IL; Rickard, CM; Ullman, AJ; Ziegenfuss, M, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Pearse, I | 1 |
| Marsh, N | 2 |
| Rickard, CM | 2 |
| Ullman, AJ | 1 |
| Larsen, E | 2 |
| Pelecanos, A | 1 |
| McGuinness, N | 1 |
| Irvine, L | 1 |
| Rapchuk, IL | 1 |
| Ziegenfuss, M | 1 |
| Corley, A | 1 |
| Webster, J | 1 |
| Choudhury, A | 1 |
| Harris, P | 1 |
| Diedrich, S | 1 |
| Müller, G | 1 |
| Sandbrink, C | 1 |
| Papke, R | 1 |
| van der Linde, J | 1 |
| Heidecke, CD | 1 |
| Parteke, LI | 1 |
| Assadian, O | 1 |
| Kramer, A | 1 |
| Röhner, E | 1 |
| Hoff, P | 1 |
| Pfitzner, T | 1 |
| Seeger, JB | 1 |
| Buttgereit, F | 1 |
| Perka, C | 1 |
| Matziolis, G | 1 |
| Altonen, M | 1 |
| SAXEN, L | 1 |
| Kosunen, T | 1 |
| Ainamo, J | 1 |
| Spiers, AS | 1 |
| Tattersall, MH | 1 |
| Gaya, H | 1 |
| Muir, IF | 1 |
| Owen, D | 1 |
| Murphy, J | 1 |
| Madsen, KL | 1 |
3 trials available for biguanides and Sepsis
| Article | Year |
|---|---|
Polyhexamethylene biguanide discs versus unmedicated dressings for prevention of central venous catheter-associated infection in the intensive care unit: A pilot randomised controlled trial to assess protocol safety and feasibility.
Topics: Adult; Bandages; Biguanides; Catheter-Related Infections; Catheterization, Central Venous; Chlorhexi | 2022 |
Chlorhexidine gluconate or polyhexamethylene biguanide disc dressing to reduce the incidence of central-line-associated bloodstream infection: a feasibility randomized controlled trial (the CLABSI trial).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bandages; Biguanides; Catheter-Related Infections; Cathe | 2017 |
Sulfamylon acetate in the treatment of pseudomonas pyocyanea infection of burns.
Topics: Adolescent; Adult; Aged; Bandages; Biguanides; Burns; Child; Clinical Trials as Topic; Female; Human | 1969 |
5 other studies available for biguanides and Sepsis
| Article | Year |
|---|---|
Efficiency of Emulsified Particle-Associated Polyhexamethylenbiguanid-Hydrochlorid (Polihexanide) for Peritoneal Lavage in a Murine Sepsis Model.
Topics: Animals; Bacterial Load; Biguanides; Cytokines; Disease Models, Animal; Disinfectants; Female; Mice; | 2018 |
Limited use of antiseptics in septic surgery.
Topics: Annexin A5; Anti-Infective Agents, Local; Apoptosis; Biguanides; Caspases; Cells, Cultured; Chlorhex | 2012 |
Effect of two antimicrobial rinses and oral prophylaxis on preoperative degerming of saliva.
Topics: Adult; Aged; Bacteria; Biguanides; Cell Count; Chlorhexidine; Humans; Middle Aged; Mouthwashes; Oral | 1976 |
Indications for systemic antibiotic prophylaxis in neutropenic patients.
Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Biguanides; Blood Cell Count; Carbenicillin; Cephalot | 1974 |
Effect of chlorhexidine mouthrinse and periodontal treatment upon bacteremia produced by oral hygiene procedures.
Topics: Administration, Topical; Adult; Biguanides; Female; Humans; Male; Middle Aged; Mouthwashes; Oral Hyg | 1974 |