nabumetone has been researched along with Rheumatoid Arthritis in 50 studies
Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diclofenac suppository, a non-steroidal anti-inflammatory drug (NSAID), is used widely in rheumatoid arthritis (RA) patients with severe arthritic pain." | 9.17 | A diclofenac suppository-nabumetone combination therapy for arthritic pain relief and a monitoring method for the diclofenac binding capacity of HSA site II in rheumatoid arthritis. ( Arimori, K; Chosa, E; Fujita, K; Kawai, K; Nishio, T; Ogata, K; Setoguchi, N; Takamura, N; Tokunaga, J; Yamamoto, R, 2013) |
| "To test the hypothesis that nabumetone (a partially selective cyclooxygenase-(COX)-2 inhibitor) has less effect on platelet aggregation than naproxen (a non-selective COX-inhibitor) in patients with rheumatoid arthritis (RA)." | 9.09 | Effects of nabumetone compared with naproxen on platelet aggregation in patients with rheumatoid arthritis. ( Knijff-Dutmer, EA; Martens, A; vd Laar, MA, 1999) |
| "The purpose of this study was to compare the tolerability and efficacy of nabumetone and naproxen in the treatment of patients with rheumatoid arthritis (RA)." | 9.09 | Tolerability and efficacy of nabumetone and naproxen in the treatment of rheumatoid arthritis. ( Berry, M; Broadwell, LK; DeLapp, R; Krug, H; Mahowald, M; Palmer, RH, 2000) |
| "To compare the efficacy and safety of nabumetone and diclofenac sodium in the treatment of patients with rheumatoid arthritis (RA)." | 9.09 | [Comparison of the efficacy and safety of nabumetone and diclofenac sodium in the treatment of patients with rheumatoid arthritis]. ( , 2001) |
| "In this double blind, randomized, parallel group study, 298 patients with rheumatoid arthritis received nabumetone (2000 mg/day) or naproxen (1000 mg/day) for 3 months." | 9.07 | Nabumetone compared with naproxen in the treatment of rheumatoid arthritis: a multicenter, double blind, randomized, parallel group trial in hospital outpatients. ( Clarke, A; Cree, F; Emery, P; Kill, D; Poland, M; Redhead, R; Williams, P, 1992) |
| "The efficacy of nabumetone was compared with that of diclofenac, naproxen, ibuprofen, and piroxicam in patients with osteoarthritis (OA) or rheumatoid arthritis (RA) in a randomized, controlled, open-label, multicenter trial." | 9.07 | Efficacy of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis. ( DeLapp, RE; Lister, BJ; Poland, M, 1993) |
| "The safety and efficacy of nabumetone and placebo were compared in a three-week, multicenter, double-blind, randomized, parallel evaluation involving patients with class II or III definite or classical rheumatoid arthritis." | 9.06 | Evaluation of nabumetone in the treatment of active adult rheumatoid arthritis. ( Collins, RL; Lanier, BG; Senter, RG; Turner, RA, 1987) |
| " The safety and efficacy of nabumetone 1,000 mg taken at bedtime was compared with that of aspirin 900 mg four times daily in the treatment of adult patients with active class II or III classical or definite rheumatoid arthritis." | 9.06 | Long-term treatment of rheumatoid arthritis comparing nabumetone with aspirin. ( Appelrouth, DJ; Bankhurst, AD; Bernhard, GC; Biundo, J; Bockow, BI; Brobyn, RD; Brodsky, AL; Burch, FX; Chang, RW; Cohen, MH, 1987) |
| "Forty-six patients with definite or classical rheumatoid arthritis were entered into a three-week, double-blind, randomized, parallel study of nabumetone, 1,000 mg at bedtime, compared with placebo." | 9.06 | Nabumetone: a single-center three-week comparison with placebo in the treatment of rheumatoid arthritis. ( Brindley, DA; Mitchell, FN; Turner, RA, 1987) |
| "Gastric tolerance to 1 g of nabumetone administered in a single nightly dose was assessed in two trials in patients with rheumatoid arthritis." | 9.06 | Endoscopic studies of nabumetone in patients with rheumatoid arthritis. A comparative endoscopic and histologic evaluation. ( Cerlek, S; Dominis, M; Greb, WH; Hauptmann, E; von Schrader, HW; Zenić, N, 1987) |
| " Therapy with nabumetone 1,000 mg given at bedtime was compared with naproxen 250 mg given twice daily in a prospective double-blind study of patients with rheumatoid arthritis." | 9.06 | Controlled evaluation of nabumetone in the treatment of active adult rheumatoid arthritis. Nabumetone versus naproxen double-blind parallel study. ( Bockow, BI; Box, P; Brodsky, AL; Espinoza, LR; Fleischmann, RM; Fogari, RA; Germain, BF; Lipani, JA; Mullen, BJ; Vasey, FB, 1987) |
| "Forty-seven patients with active rheumatoid arthritis were entered into a single-blind study to compare the safety and efficacy of nabumetone with naproxen." | 9.06 | Single-blind comparative study of nabumetone (Relafen) versus naproxen in the treatment of rheumatoid arthritis. ( Hazleman, BL; Thomas, PP, 1987) |
| "A single-blind crossover study of two non-steroidal anti-inflammatory drugs, nabumetone (1000 mg/day) and naproxen (500 mg/day) was performed in thirty patients suffering from definite or classical rheumatoid arthritis." | 9.05 | A comparative study of the effectiveness and safety of two non-steroidal anti-inflammatory agents, nabumetone and naproxen in rheumatoid arthritis. ( Croydon, EA; Fostiropoulos, G, 1982) |
| " Nabumetone (Relafen), a new NSAID for the treatment of rheumatoid arthritis (RA) and osteoarthritis (OA), may differ from the others." | 8.78 | Nabumetone: a new NSAID for rheumatoid arthritis and osteoarthritis. ( Roth, SH, 1992) |
| "In an open uncontrolled trial 30 patients (4 males, 26 females) aged 43-70 years suffering from active rheumatoid arthritis (diagnosis based on American Rheumatoid Association criteria) were treated with nabumetone (one 1 g capsule daily per os)." | 7.68 | [Evaluation of tolerability and efficacy of a nabumetone preparation in the treatment of patients with rheumatoid arthritis]. ( Alianti, M; Lotta, C; Vaiani, G, 1990) |
| "We evaluated the effectiveness and the tolerability of a new non steroidal antiinflammatory drug (NSAID), nabumetone (1 g/daily for at least 8 days), in 20 patients (10 males and 10 females), 4 with rheumatoid arthritis and 16 with osteoarthritis." | 7.68 | [Efficacy and tolerability of nabumetone in the treatment of painful symptomatology of rheumatoid arthritis and osteoarthrosis]. ( Iagnocco, A; Riccieri, V; Spadaro, A, 1991) |
| " The incidence of > or = 1 adverse event considered by the investigator to be related or probably related to therapy was similar in all groups." | 6.67 | Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis. ( DeLapp, RE; Eversmeyer, W; Jensen, CP; Poland, M, 1993) |
| " The most common adverse effects that occurred were related to the gastrointestinal tract, nervous system, skin, and special senses." | 6.67 | Clinical efficacy and safety of nabumetone in rheumatoid arthritis and osteoarthritis. ( Fleischmann, RM, 1992) |
| " The dosage of nabumetone was gradually increased." | 6.66 | Nabumetone in the treatment of active adult rheumatoid arthritis. ( Brobyn, RD, 1987) |
| " The most frequent adverse effects are those commonly seen with COX inhibitors, which include diarrhoea, dyspepsia, headache, abdominal pain and nausea." | 6.42 | Nabumetone: therapeutic use and safety profile in the management of osteoarthritis and rheumatoid arthritis. ( Ekbom, A; Hedner, T; Samulesson, O; Ung, KA; Wadenvik, H; Währborg, P, 2004) |
| "Diclofenac suppository, a non-steroidal anti-inflammatory drug (NSAID), is used widely in rheumatoid arthritis (RA) patients with severe arthritic pain." | 5.17 | A diclofenac suppository-nabumetone combination therapy for arthritic pain relief and a monitoring method for the diclofenac binding capacity of HSA site II in rheumatoid arthritis. ( Arimori, K; Chosa, E; Fujita, K; Kawai, K; Nishio, T; Ogata, K; Setoguchi, N; Takamura, N; Tokunaga, J; Yamamoto, R, 2013) |
| "To test the hypothesis that nabumetone (a partially selective cyclooxygenase-(COX)-2 inhibitor) has less effect on platelet aggregation than naproxen (a non-selective COX-inhibitor) in patients with rheumatoid arthritis (RA)." | 5.09 | Effects of nabumetone compared with naproxen on platelet aggregation in patients with rheumatoid arthritis. ( Knijff-Dutmer, EA; Martens, A; vd Laar, MA, 1999) |
| "The purpose of this study was to compare the tolerability and efficacy of nabumetone and naproxen in the treatment of patients with rheumatoid arthritis (RA)." | 5.09 | Tolerability and efficacy of nabumetone and naproxen in the treatment of rheumatoid arthritis. ( Berry, M; Broadwell, LK; DeLapp, R; Krug, H; Mahowald, M; Palmer, RH, 2000) |
| "To compare the efficacy and safety of nabumetone and diclofenac sodium in the treatment of patients with rheumatoid arthritis (RA)." | 5.09 | [Comparison of the efficacy and safety of nabumetone and diclofenac sodium in the treatment of patients with rheumatoid arthritis]. ( , 2001) |
| "The objective of this endoscopic, double-blind study was to evaluate the gastric tolerability of nabumetone, a novel nonsteroidal anti-inflammatory drug, compared with naproxen in patients with rheumatoid arthritis." | 5.08 | Gastroduodenal tolerability of nabumetone versus naproxen in the treatment of rheumatic patients. ( Bianchi Porro, G; Caruso, I; Imbesi, V; Montrone, F; Petrillo, M, 1995) |
| "We evaluated the clinical efficacy and the tolerance of Nabumetone (N), in comparison with a pool of non-steroidal anti-inflammatory drugs (NSAIDs), in a cohort of patients affected by rheumatoid arthritis, osteoarthritis, non-articular rheumatisms and primary fibromyalgic syndrome." | 5.08 | Clinical efficacy and tolerance of nabumetone in articular and non-articular rheumatic disorders: personal experience during 12 weeks of treatment. ( Allegra, A; Coaccioli, S; Di Cato, L; Puxeddu, A, 1998) |
| "In this double blind, randomized, parallel group study, 298 patients with rheumatoid arthritis received nabumetone (2000 mg/day) or naproxen (1000 mg/day) for 3 months." | 5.07 | Nabumetone compared with naproxen in the treatment of rheumatoid arthritis: a multicenter, double blind, randomized, parallel group trial in hospital outpatients. ( Clarke, A; Cree, F; Emery, P; Kill, D; Poland, M; Redhead, R; Williams, P, 1992) |
| "To compare the gastrointestinal safety, ulcerogenic potential, and clinical efficacy over 5 years of nabumetone and naproxen therapy, in patients with rheumatoid arthritis (RA) or osteoarthritis (OA)." | 5.07 | A longterm endoscopic evaluation of patients with arthritis treated with nabumetone vs naproxen. ( Bennett, R; Caldron, P; Koepp, R; Mitchell, C; Roth, SH; Swenson, C, 1994) |
| "The efficacy of nabumetone was compared with that of diclofenac, naproxen, ibuprofen, and piroxicam in patients with osteoarthritis (OA) or rheumatoid arthritis (RA) in a randomized, controlled, open-label, multicenter trial." | 5.07 | Efficacy of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis. ( DeLapp, RE; Lister, BJ; Poland, M, 1993) |
| "In a randomized, open-label, controlled, multicenter, 12-week study, the efficacy and safety of nabumetone (1,000-2,000 mg/day) versus diclofenac (100-200 mg/day), naproxen (500-1,500 mg/day), ibuprofen (1,200-3,200 mg/day), or piroxicam (10-20 mg/day) were evaluated in patients with osteoarthritis (OA) or rheumatoid arthritis (RA)." | 5.07 | Efficacy and safety of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in the elderly. ( DeLapp, RE; Morgan, GJ; Poland, M, 1993) |
| "A total of 1,924 persons (rheumatoid arthritis, 835; osteoarthritis, 1,073; volunteers, 16) received nabumetone in United States clinical trials." | 5.06 | Safety evaluation of nabumetone in United States clinical trials. ( Brindley, DA; Jackson, RE; Mitchell, FN, 1987) |
| "Gastric tolerance to 1 g of nabumetone administered in a single nightly dose was assessed in two trials in patients with rheumatoid arthritis." | 5.06 | Endoscopic studies of nabumetone in patients with rheumatoid arthritis. A comparative endoscopic and histologic evaluation. ( Cerlek, S; Dominis, M; Greb, WH; Hauptmann, E; von Schrader, HW; Zenić, N, 1987) |
| "Forty-six patients with definite or classical rheumatoid arthritis were entered into a three-week, double-blind, randomized, parallel study of nabumetone, 1,000 mg at bedtime, compared with placebo." | 5.06 | Nabumetone: a single-center three-week comparison with placebo in the treatment of rheumatoid arthritis. ( Brindley, DA; Mitchell, FN; Turner, RA, 1987) |
| " The safety and efficacy of nabumetone 1,000 mg taken at bedtime was compared with that of aspirin 900 mg four times daily in the treatment of adult patients with active class II or III classical or definite rheumatoid arthritis." | 5.06 | Long-term treatment of rheumatoid arthritis comparing nabumetone with aspirin. ( Appelrouth, DJ; Bankhurst, AD; Bernhard, GC; Biundo, J; Bockow, BI; Brobyn, RD; Brodsky, AL; Burch, FX; Chang, RW; Cohen, MH, 1987) |
| "The safety and efficacy of nabumetone and placebo were compared in a three-week, multicenter, double-blind, randomized, parallel evaluation involving patients with class II or III definite or classical rheumatoid arthritis." | 5.06 | Evaluation of nabumetone in the treatment of active adult rheumatoid arthritis. ( Collins, RL; Lanier, BG; Senter, RG; Turner, RA, 1987) |
| " Therapy with nabumetone 1,000 mg given at bedtime was compared with naproxen 250 mg given twice daily in a prospective double-blind study of patients with rheumatoid arthritis." | 5.06 | Controlled evaluation of nabumetone in the treatment of active adult rheumatoid arthritis. Nabumetone versus naproxen double-blind parallel study. ( Bockow, BI; Box, P; Brodsky, AL; Espinoza, LR; Fleischmann, RM; Fogari, RA; Germain, BF; Lipani, JA; Mullen, BJ; Vasey, FB, 1987) |
| "Forty-seven patients with active rheumatoid arthritis were entered into a single-blind study to compare the safety and efficacy of nabumetone with naproxen." | 5.06 | Single-blind comparative study of nabumetone (Relafen) versus naproxen in the treatment of rheumatoid arthritis. ( Hazleman, BL; Thomas, PP, 1987) |
| "A single-blind crossover study of two non-steroidal anti-inflammatory drugs, nabumetone (1000 mg/day) and naproxen (500 mg/day) was performed in thirty patients suffering from definite or classical rheumatoid arthritis." | 5.05 | A comparative study of the effectiveness and safety of two non-steroidal anti-inflammatory agents, nabumetone and naproxen in rheumatoid arthritis. ( Croydon, EA; Fostiropoulos, G, 1982) |
| "Nabumetone, 500 mg two nocte, was compared with naproxen, 250 mg two nocte and one mane, in the management of 24 patients with rheumatoid arthritis attending an outpatients clinic." | 5.05 | Nabumetone, a new non-steroidal anti-inflammatory drug: a comparison with naproxen. ( Burry, HC; Mowles, E; Richards, AM; Treadwell, BL; Tweed, JM, 1983) |
| " Nabumetone (Relafen), a new NSAID for the treatment of rheumatoid arthritis (RA) and osteoarthritis (OA), may differ from the others." | 4.78 | Nabumetone: a new NSAID for rheumatoid arthritis and osteoarthritis. ( Roth, SH, 1992) |
| " A MEDLINE search was conducted using the following indexing terms: antiinflammatory agents, nonsteroidal, nabumetone, rheumatoid arthritis (RA), and osteoarthritis (OA)." | 4.78 | Nabumetone: a "nonacidic" nonsteroidal antiinflammatory drug. ( Dahl, SL, 1993) |
| "Nabumetone is a new non-steroidal anti-inflammatory drug advocated for use in the symptomatic treatment of rheumatic and inflammatory conditions." | 3.76 | Nabumetone. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases. ( Friedel, HA; Todd, PA, 1988) |
| "We evaluated the effectiveness and the tolerability of a new non steroidal antiinflammatory drug (NSAID), nabumetone (1 g/daily for at least 8 days), in 20 patients (10 males and 10 females), 4 with rheumatoid arthritis and 16 with osteoarthritis." | 3.68 | [Efficacy and tolerability of nabumetone in the treatment of painful symptomatology of rheumatoid arthritis and osteoarthrosis]. ( Iagnocco, A; Riccieri, V; Spadaro, A, 1991) |
| "In an open uncontrolled trial 30 patients (4 males, 26 females) aged 43-70 years suffering from active rheumatoid arthritis (diagnosis based on American Rheumatoid Association criteria) were treated with nabumetone (one 1 g capsule daily per os)." | 3.68 | [Evaluation of tolerability and efficacy of a nabumetone preparation in the treatment of patients with rheumatoid arthritis]. ( Alianti, M; Lotta, C; Vaiani, G, 1990) |
| " The incidence of > or = 1 adverse event considered by the investigator to be related or probably related to therapy was similar in all groups." | 2.67 | Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis. ( DeLapp, RE; Eversmeyer, W; Jensen, CP; Poland, M, 1993) |
| " The most common adverse effects that occurred were related to the gastrointestinal tract, nervous system, skin, and special senses." | 2.67 | Clinical efficacy and safety of nabumetone in rheumatoid arthritis and osteoarthritis. ( Fleischmann, RM, 1992) |
| "The nabumetone-treated group also showed greater improvement in all efficacy variables, with significant improvement noted in three of these five variables in both rheumatoid and osteoarthritic patients." | 2.66 | Endoscopy-controlled study of the safety of nabumetone compared with naproxen in arthritis therapy. ( Roth, SH, 1987) |
| " The dosage of nabumetone was gradually increased." | 2.66 | Nabumetone in the treatment of active adult rheumatoid arthritis. ( Brobyn, RD, 1987) |
| " The most frequent adverse effects are those commonly seen with COX inhibitors, which include diarrhoea, dyspepsia, headache, abdominal pain and nausea." | 2.42 | Nabumetone: therapeutic use and safety profile in the management of osteoarthritis and rheumatoid arthritis. ( Ekbom, A; Hedner, T; Samulesson, O; Ung, KA; Wadenvik, H; Währborg, P, 2004) |
| "Oxaprozin is an effective, long-acting anti-inflammatory analgesic, but its comparative advantages remain undefined." | 2.39 | A review of selected newer nonsteroidal anti-inflammatory drugs. ( Amadio, P; Cummings, DM, 1994) |
| "We have performed a detailed pharmacokinetic study of the plasma concentrations of the major active metabolite of nabumetone, 6-methoxy-2-naphthylacetic acid (6 MNA), attained after a single dose and during chronic administration comparing the results of a group of young healthy volunteers with those of a group of elderly arthritic patients." | 1.28 | A pharmacokinetic study of the active metabolite of nabumetone in young healthy subjects and older arthritis patients. ( Chellingsworth, MC; Jubb, R; Kendall, MJ; Kill, DC; Thawley, AR; Undre, NA, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (34.00) | 18.7374 |
| 1990's | 26 (52.00) | 18.2507 |
| 2000's | 6 (12.00) | 29.6817 |
| 2010's | 1 (2.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Setoguchi, N | 1 |
| Takamura, N | 1 |
| Fujita, K | 1 |
| Ogata, K | 1 |
| Tokunaga, J | 1 |
| Nishio, T | 1 |
| Chosa, E | 1 |
| Arimori, K | 1 |
| Kawai, K | 1 |
| Yamamoto, R | 1 |
| Shi, W | 2 |
| Wang, YM | 2 |
| Cheng, NN | 2 |
| Chen, BY | 2 |
| Li, D | 2 |
| Li, SL | 1 |
| Yan, M | 1 |
| Heyll, U | 1 |
| Hedner, T | 1 |
| Samulesson, O | 1 |
| Währborg, P | 1 |
| Wadenvik, H | 1 |
| Ung, KA | 1 |
| Ekbom, A | 1 |
| Richards, AM | 1 |
| Burry, HC | 1 |
| Treadwell, BL | 1 |
| Tweed, JM | 1 |
| Mowles, E | 1 |
| Fostiropoulos, G | 1 |
| Croydon, EA | 1 |
| Bianchi Porro, G | 1 |
| Montrone, F | 1 |
| Petrillo, M | 1 |
| Caruso, I | 1 |
| Imbesi, V | 1 |
| Roth, SH | 3 |
| Bennett, R | 1 |
| Caldron, P | 1 |
| Mitchell, C | 1 |
| Swenson, C | 1 |
| Koepp, R | 1 |
| Helfgott, SM | 1 |
| Cummings, DM | 1 |
| Amadio, P | 1 |
| Eversmeyer, W | 1 |
| Poland, M | 4 |
| DeLapp, RE | 3 |
| Jensen, CP | 1 |
| Morgan, GJ | 1 |
| Lister, BJ | 1 |
| Dahl, SL | 1 |
| Richardson, CE | 1 |
| Emery, P | 2 |
| Gołab, T | 1 |
| Jonderko, G | 1 |
| Straszecka, J | 1 |
| Krzewiński, W | 1 |
| Kucharz, EJ | 1 |
| Klimczak-Gołab, L | 1 |
| Nasonov, EL | 1 |
| Nasonova, SV | 1 |
| Coaccioli, S | 1 |
| Allegra, A | 1 |
| Di Cato, L | 1 |
| Puxeddu, A | 1 |
| Knijff-Dutmer, EA | 1 |
| Martens, A | 1 |
| vd Laar, MA | 1 |
| Krug, H | 1 |
| Broadwell, LK | 1 |
| Berry, M | 1 |
| DeLapp, R | 1 |
| Palmer, RH | 1 |
| Mahowald, M | 1 |
| Huskisson, EC | 1 |
| Irani, M | 1 |
| Fleischmann, R | 1 |
| Fleischmann, RM | 2 |
| Clarke, A | 1 |
| Williams, P | 1 |
| Kill, D | 1 |
| Cree, F | 1 |
| Redhead, R | 1 |
| Riccieri, V | 1 |
| Spadaro, A | 1 |
| Iagnocco, A | 1 |
| Stroehmann, I | 2 |
| Fedder, M | 1 |
| Zeidler, H | 1 |
| Miehlke, RK | 1 |
| Schneider, S | 1 |
| Sörgel, F | 1 |
| Muth, P | 1 |
| Henschke, F | 1 |
| Giersch, KH | 1 |
| Münzel, P | 1 |
| Gam, A | 1 |
| Nawrocki, A | 1 |
| Danneskiold-Samsøe, B | 1 |
| Alianti, M | 1 |
| Lotta, C | 1 |
| Vaiani, G | 1 |
| Kendall, MJ | 1 |
| Chellingsworth, MC | 1 |
| Jubb, R | 1 |
| Thawley, AR | 1 |
| Undre, NA | 1 |
| Kill, DC | 1 |
| Lemmel, EM | 1 |
| Friedel, HA | 1 |
| Todd, PA | 1 |
| Jenner, PN | 1 |
| Johnson, ES | 1 |
| Jackson, RE | 1 |
| Mitchell, FN | 2 |
| Brindley, DA | 2 |
| Greb, WH | 1 |
| von Schrader, HW | 1 |
| Cerlek, S | 1 |
| Dominis, M | 1 |
| Hauptmann, E | 1 |
| Zenić, N | 1 |
| Turner, RA | 2 |
| Bernhard, GC | 1 |
| Appelrouth, DJ | 1 |
| Bankhurst, AD | 1 |
| Biundo, J | 1 |
| Bockow, BI | 2 |
| Brobyn, RD | 2 |
| Brodsky, AL | 2 |
| Burch, FX | 1 |
| Chang, RW | 1 |
| Cohen, MH | 1 |
| Lanier, BG | 1 |
| Collins, RL | 1 |
| Senter, RG | 1 |
| Vasey, FB | 1 |
| Germain, BF | 1 |
| Espinoza, LR | 1 |
| Box, P | 1 |
| Lipani, JA | 1 |
| Mullen, BJ | 1 |
| Fogari, RA | 1 |
| Hazleman, BL | 1 |
| Thomas, PP | 1 |
| Komatsubara, Y | 1 |
| Ogawa, Y | 1 |
| Nobenaga, T | 1 |
11 reviews available for nabumetone and Rheumatoid Arthritis
| Article | Year |
|---|---|
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans | 2003 |
Nabumetone: therapeutic use and safety profile in the management of osteoarthritis and rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bu | 2004 |
Nabumetone: a clinical appraisal.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; | 1994 |
A review of selected newer nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; | 1994 |
Nabumetone: a "nonacidic" nonsteroidal antiinflammatory drug.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Drug Interactions; Humans | 1993 |
Innovative treatment approaches for rheumatoid arthritis. New cyclo-oxygenase and cytokine inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Cyclooxygenase I | 1995 |
[Nabumetone, a new nonsteroidal antiinflammatory agent: clinical prospects].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Drug Evaluation; | 1996 |
Efficacy and improved safety--a new anti-arthritic agent.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Controlled C | 1991 |
Nabumetone: a new NSAID for rheumatoid arthritis and osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Humans; Nabumetone; Osteo | 1992 |
Nabumetone (Relifex)--another NSAID.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Humans; Nabumetone; Osteo | 1988 |
Nabumetone. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; | 1988 |
28 trials available for nabumetone and Rheumatoid Arthritis
| Article | Year |
|---|---|
A diclofenac suppository-nabumetone combination therapy for arthritic pain relief and a monitoring method for the diclofenac binding capacity of HSA site II in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Binding Sites; Butanones; Cyclooxygenase Inhibitors; Diclofenac; Drug M | 2013 |
Nabumetone, a new non-steroidal anti-inflammatory drug: a comparison with naproxen.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Double-Blind M | 1983 |
A comparative study of the effectiveness and safety of two non-steroidal anti-inflammatory agents, nabumetone and naproxen in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Female; Humans | 1982 |
Gastroduodenal tolerability of nabumetone versus naproxen in the treatment of rheumatic patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Double-Blind Method; Duod | 1995 |
A longterm endoscopic evaluation of patients with arthritis treated with nabumetone vs naproxen.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Double-Blind Method | 1994 |
Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; | 1993 |
Efficacy and safety of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in the elderly.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; | 1993 |
Efficacy of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; | 1993 |
Clinical efficacy and tolerance of nabumetone in articular and non-articular rheumatic disorders: personal experience during 12 weeks of treatment.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Female; Huma | 1998 |
Effects of nabumetone compared with naproxen on platelet aggregation in patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheu | 1999 |
Tolerability and efficacy of nabumetone and naproxen in the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Buta | 2000 |
[Comparison of the efficacy and safety of nabumetone and diclofenac sodium in the treatment of patients with rheumatoid arthritis].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; | 2001 |
Clinical efficacy and safety of nabumetone in rheumatoid arthritis and osteoarthritis.
Topics: Adult; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Butanon | 1992 |
Nabumetone compared with naproxen in the treatment of rheumatoid arthritis: a multicenter, double blind, randomized, parallel group trial in hospital outpatients.
Topics: Adult; Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; D | 1992 |
German drug monitoring studies with nabumetone.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; | 1990 |
Penetration of the active metabolite of nabumetone into synovial fluid and adherent tissue of patients undergoing knee joint surgery.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; B | 1990 |
Nabumetone. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; | 1988 |
Review of the experience with nabumetone in clinical trials outside of the United States.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Athletic Injuries; Butanones; | 1987 |
Safety evaluation of nabumetone in United States clinical trials.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Tri | 1987 |
Endoscopy-controlled study of the safety of nabumetone compared with naproxen in arthritis therapy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Tri | 1987 |
Endoscopic studies of nabumetone in patients with rheumatoid arthritis. A comparative endoscopic and histologic evaluation.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Butanones; Clin | 1987 |
Nabumetone: a single-center three-week comparison with placebo in the treatment of rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as | 1987 |
Long-term treatment of rheumatoid arthritis comparing nabumetone with aspirin.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Bu | 1987 |
Evaluation of nabumetone in the treatment of active adult rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; | 1987 |
Controlled evaluation of nabumetone in the treatment of active adult rheumatoid arthritis. Nabumetone versus naproxen double-blind parallel study.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; | 1987 |
Nabumetone in the treatment of active adult rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; | 1987 |
Single-blind comparative study of nabumetone (Relafen) versus naproxen in the treatment of rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; | 1987 |
[Clinical trials of nabumetone in therapy of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Double-Blind Method; Female | 1987 |
12 other studies available for nabumetone and Rheumatoid Arthritis
| Article | Year |
|---|---|
Risk factors of adverse drug reaction from non-steroidal anti-inflammatory drugs in Shanghai patients with arthropathy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheu | 2004 |
[Orthokin as new therapeutic option for orthopedic diseases].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Transfusion, Autologous; Butan | 2004 |
[Investigations concerning the effect of nabumetone on gastric mucosa].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Butanones; Drug Admi | 1996 |
NSAIDs for the new decade--nabumetone?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Gastrointestinal Hemorrha | 1991 |
The long-term U.S. study--a report on outcome and tolerance.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as | 1991 |
Progress in Arthritis Therapy: Nabumetone Investigators' Meeting. Proceedings. Scottsdale, Arizona, September 27-28, 1991.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Humans; Nabumetone | 1992 |
Nabumetone--a new NSAID.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; | 1992 |
[Efficacy and tolerability of nabumetone in the treatment of painful symptomatology of rheumatoid arthritis and osteoarthrosis].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Drug Evaluat | 1991 |
Effect of nabumetone on patients with RA evaluated by isokinetic muscle strength.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Female; Huma | 1990 |
[Evaluation of tolerability and efficacy of a nabumetone preparation in the treatment of patients with rheumatoid arthritis].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Drug Evaluat | 1990 |
A pharmacokinetic study of the active metabolite of nabumetone in young healthy subjects and older arthritis patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal; Arthriti | 1989 |
[Treatment of rheumatic diseases with nabumetone. Results of a study using the drug in 18,046 patients].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheu | 1988 |