tetradecanoylphorbol acetate has been researched along with Rheumatoid Arthritis in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (17.39) | 18.7374 |
| 1990's | 44 (47.83) | 18.2507 |
| 2000's | 24 (26.09) | 29.6817 |
| 2010's | 7 (7.61) | 24.3611 |
| 2020's | 1 (1.09) | 2.80 |
| Authors | Studies |
|---|---|
| Bala, A; Chetia, P; Haldar, PK; Khandelwal, B | 1 |
| Mitchell, TS; Moots, RJ; Wright, HL | 1 |
| Holmes, CL; Johnson, CJ; Kernien, J; Nett, JE; Shelef, MA; Shim, D | 1 |
| Ding, J; Feng, Y; Li, X; Luo, X; Miao, J; Wu, Z; Zheng, Z; Zhu, P | 1 |
| Lee, J; Lingampalli, N; Luria, A; Rada, B; Raghu, H; Rhodes, C; Robinson, WH; Sharpe, O; Sohn, DH; Sokolove, J | 1 |
| Cheng, LF; Feng, L; Leng, JH; Lu, Y; Wang, WJ; Yao, HP | 1 |
| Huang, Q; Mandelin, AM; Pope, RM; Shahrara, S | 1 |
| Akhavanpoor, M; Bea, F; Blank, N; Celik, S; Dengler, TJ; Erbel, C; Hippe, HJ; Katus, HA; Richter, A; Shankar, V; Urban, S; Wambsganss, N | 1 |
| Fujii, T; Hashimoto, M; Iguchi-Hashimoto, M; Ito, H; Ito, Y; Kawabata, D; Kobayashi, S; Mimori, T; Nakamura, T; Nojima, T; Ohmura, K; Sakaguchi, N; Sakaguchi, S; Shimizu, M; Usui, T; Yoshifuji, H; Yoshitomi, H; Yukawa, N | 1 |
| Benito, JM; Marco, FM; Marín-Alberca, G; Navarro-Blasco, FJ; Pérez-García, V; Peris-Pertusa, A; Sempere-Ortells, JM; Zubcoff, JJ | 1 |
| Baerwald, C; Kraus, S; Pierer, M; Rossol, M; Wagner, U | 1 |
| da Rocha, LF; Dantas, AT; Duarte, ÂL; Galdino, SL; Mariz, HA; Pitta, Ida R; Pitta, MG | 1 |
| Becker, T; Dietersdorfer, E; Kiener, H; Kloesch, B; Steiner, G | 1 |
| Han, MK; Hwang, BY; Kim, JR; Kim, JS; Lee, HY; Park, BH; Song, EK; Yoo, WH | 1 |
| Aicher, WK; Schuler, MK | 1 |
| Bridts, CH; De Clerck, LS; Schuerwegh, AJ; Stevens, WJ | 1 |
| Ahmed, S; Brennan, FM; Feldmann, M; Field, S; Foey, AD; Jain, A; Williams, R | 1 |
| Baik, KU; Cho, JY; Kim, HP; Lee, JG; Park, JS; Park, MH; Yoo, ES | 1 |
| Atzeni, F; Bonara, P; Capsoni, F; Carrabba, M; Doria, A; Minonzio, F; Sarzi-Puttini, P | 1 |
| Fan, CM; Li, HM; Li, XY; Lu, N; Wang, YH; Zheng, ZH; Zhu, P | 1 |
| Barton, CH; Birts, CN; Wilton, DC | 1 |
| Burmester, GR; Buttgereit, F; Dziurla, R; Erekul, K; Gaber, T; Grützkau, A; Häupl, T; Radbruch, A; Scheffold, A; Tripmacher, R; Tschirschmann, M | 1 |
| Dovigo, L; Marangoni, C; Spisani, S; Traniello, S | 1 |
| Ben-Av, P; Crofford, LJ; Hla, T; Wilder, RL | 1 |
| Chu, CQ; Cohen, SB; Feldmann, M; Katsikis, PD; Londei, M; Maini, RN; Thomssen, H; Webb, LM | 1 |
| Dayer, JM; Lacraz, S; Miltenburg, AM; Welgus, HG | 1 |
| Bucknall, RC; Edwards, SW; Phelan, M; Robinson, JJ; Watson, F | 1 |
| Crofford, LJ; Epps, HR; Hla, T; Remmers, EF; Ristimäki, AP; Sano, H; Wilder, RL | 1 |
| Helve, T; Kurki, P; Virtanen, I; Walle, TK | 1 |
| Federlin, K; Marhoffer, W; Stein, M | 1 |
| Lees, M; Nagase, H; Ogata, Y; Tetlow, LC; Woolley, DE | 1 |
| Leirisalo-Repo, M; Paimela, L; Repo, H | 1 |
| Griffiths, HR; Lunec, J | 1 |
| Bartlett, RR; Dimitrijevic, M | 1 |
| Kobayashi, M; Kuroda, A; Mino, T; Sugiyama, E; Taki, H | 1 |
| Blackburn, WD; Minghetti, PP; Zhang, HG | 1 |
| Bavington, C; Brennan, FR; Glant, TT; Jobanputra, P; Mikecz, K; Morrison, P; Nuki, G; Pinder, S | 1 |
| Abe, M; Eto, S; Hubscher, S; Morimoto, I; Nakatsuka, K; Saito, K; Tanaka, Y; Wake, A | 1 |
| Aoyagi, T; Eguchi, K; Kawabe, Y; Kawakami, A; Matsuoka, N; Nagataki, S; Tsuboi, M | 1 |
| Inagaki, C; Mishima, K; Ogawa, R; Otani, H; Tanabe, T | 1 |
| Coffey, D; Cronstein, BN; Fisher, R; Lahita, RG; Merrill, JT; Salmon, J; Schreibman, D; Shen, C; Zakharenko, O | 1 |
| Ding, Y; Hanemaaijer, R; Helaakoski, T; Kainulainen, T; Konttinen, YT; Rönkä, H; Salo, T; Sorsa, T; Sutinen, M; Tschesche, H; van Hinsbergh, VW; Visser, H | 1 |
| Connor, JR; Dodds, R; Emery, JG; Kirkpatrick, RB; Lysko, PG; Rosenberg, M | 1 |
| Benton, HP; Loredo, GA | 1 |
| Bordin, G; Brunelleschi, S; Colangelo, D; Viano, I | 1 |
| Arkell, J; Jackson, CJ; Nguyen, M | 1 |
| Kobayashi, M; Kuroda, A; Maruyama, M; Mino, T; Sugiyama, E; Taki, H; Yamashita, N | 1 |
| Grunert, F; Hönig, M; Jantscheff, P; Peter, HH | 1 |
| Bijlsma, JW; Glaudemans, CA; Lafeber, FP; Van Roon, JA; Verhoef, CM; Vianen, ME | 1 |
| Anderegg, U; Haustein, UF; Saalbach, A; Wetzig, T | 1 |
| Corrigall, VM; Garyfallos, A; Panayi, GS | 1 |
| Chwalinska-Sadowska, H; Klimczak, E; Koc, A; Ksiezopolska-Pietrzak, K; Luszczykiewicz, G; Maslinski, W; Ziolkowska, M | 1 |
| Bridts, CH; De Clerck, LS; Mertens, AV; Moens, MM; Stevens, WJ | 1 |
| Hause, B; Kehlen, A; Langner, J; Riemann, D; Röntsch, J | 1 |
| Gajewski, M; Gujski, M; Maslinski, S; Poppe, P; Szukiewicz, D; Wojtecka-Lukasik, E | 1 |
| Chihara, K; Doita, M; Kawasaki, H; Morisawa, T; Nakamura, M; Shimizu, K; Shiozawa, K; Shiozawa, S; Yamamoto, E; Yonehara, S; Yoshikawa, N | 1 |
| Eichler, W | 1 |
| Aznavoorian, S; Engler, JA; Moore, BA; Windsor, LJ | 1 |
| Arnhold, J; Arnold, K; Benard, S; Reichl, S; Schiller, J | 1 |
| Bordin, G; Brunelleschi, S; Colangelo, D; Lavagno, L; Viano, I | 1 |
| Breedveld, FC; Ezendam, NP; Levarht, EW; Reparon-Schuijt, CC; van Esch, WJ; van Kooten, C; Verweij, CL | 1 |
| Aurer, A; Bernimoulin, JP; Burmester, GR; Kolkenbrock, H; Sittinger, M; Smolian, H; Zacher, J | 1 |
| Freemont, AJ; Hayes, ME; Mawer, EB; Yuan, JY | 1 |
| Taylor, DJ | 1 |
| Auble, DT; Brinckerhoff, CE; Karmilowicz, MJ; Sirum-Connolly, KL | 1 |
| Chartrain, N; Hutchinson, NI; Lark, M; MacNaul, KL; Tocci, MJ | 2 |
| Blackburn, WD; Chatham, WW; Heck, LW | 1 |
| Altomonte, L; De Leo, E; De Sole, P; Di Mario, G; Magarò, M; Mirone, L; Zoli, A | 1 |
| Adamson, H; Bell, AL; Kirk, F; McCaigue, MD; Rotman, H | 1 |
| Kemppinen, P; Konttinen, YT; Lindy, O; Lindy, S; Saari, H; Sorsa, T; Suomalainen, K; Vauhkonen, M | 1 |
| Chang, FY; Chang, ML; Chou, CT; Shaio, MF | 1 |
| Bucknall, RC; Edwards, SW; Nurcombe, HL | 1 |
| Brinckerhoff, CE | 1 |
| Cencetti, A; De Martino, M; Graziani, E; Maddali Bongi, S; Palermo, C; Pavari, E; Zoppi, M | 1 |
| Davis, W; Emmrich, F; Fox, DA; Higgs, J; Kan, L; Kinne, RW; Millard, JA; Zeldes, WS | 1 |
| Banchereau, J; Dupuy d'Angeac, A; Miossec, P; Naviliat, M; Sany, J | 1 |
| Egeland, T; Gaudernack, G; Hovdenes, J; Kvien, TK; Mellbye, OJ | 1 |
| Dang, H; Dauphinée, MJ; Flescher, E; Galarza, D; Hempel, K; Talal, N; Wilson-Burris, K | 1 |
| Frisch, SM; Ruley, HE | 1 |
| Dieppe, PA; Dularay, B; Elson, CJ | 1 |
| Kingsley, GH; Panayi, GS; Pitzalis, C | 1 |
| Bacon, PA; Blake, DR; Brailsford, S; Lunec, J; McCleary, SJ | 1 |
| Beindorff, CM; Biemond, P; Koster, JF; Penders, JM; Swaak, AJ | 1 |
| Niwa, Y; Ohashi, T; Ozaki, Y | 1 |
| Baricordi, RO; Damiani, G; Dovigo, L; Gavioli, R; Sensi, A; Spisani, S; Traniello, S | 1 |
| Bender, JG; Searles, R; Van Epps, DE; Williams, RC | 1 |
| Bourbigot, B; Jouquan, J; Le Goff, P; Le Saout, J; Lydyard, PM; Mackenzie, L; Youinou, P | 1 |
| Jouquan, J; Le Goff, P; Lydyard, PM; Mackenzie, L; Youinou, P | 1 |
| Binz, H; Felder, M; Fontana, A; Stolzenburg, T; Wagenhaeuser, FJ | 1 |
| Andary, M; Clot, J; Combe, B; Klein, B; Sany, J | 1 |
| Barrett, ML; Edwards, MC; Evans, FJ; Gordon, D | 1 |
2 trial(s) available for tetradecanoylphorbol acetate and Rheumatoid Arthritis
| Article | Year |
|---|---|
Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis.
Topics: Adalimumab; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antirheumatic Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Biomarkers; CD11b Antigen; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Female; Gene Expression Regulation; Humans; Immunophenotyping; Lectins, C-Type; Luminescent Measurements; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 2005 |
Chemiluminescence responses and chemotaxis of monocytes from patients with early rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Chemotaxis, Leukocyte; Female; Humans; Luminescent Measurements; Male; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Rheumatoid Factor; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
90 other study(ies) available for tetradecanoylphorbol acetate and Rheumatoid Arthritis
| Article | Year |
|---|---|
Dietary Antioxidants Significantly Reduced Phorbol Myristate Acetate Induced Oxidative Stress of Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis.
Topics: Adult; Antioxidants; Arthritis, Rheumatoid; Cells, Cultured; Dietary Supplements; Female; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Oxidative Stress; Tetradecanoylphorbol Acetate; Young Adult | 2021 |
Janus kinase inhibitors prevent migration of rheumatoid arthritis neutrophils towards interleukin-8, but do not inhibit priming of the respiratory burst or reactive oxygen species production.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azetidines; Case-Control Studies; Cell Movement; Cells, Cultured; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Janus Kinases; Male; Middle Aged; Neutrophils; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyrimidines; Pyrroles; Reactive Oxygen Species; Respiratory Burst; Sulfonamides; Tetradecanoylphorbol Acetate; United Kingdom | 2017 |
Insight into Neutrophil Extracellular Traps through Systematic Evaluation of Citrullination and Peptidylarginine Deiminases.
Topics: Animals; Arthritis, Rheumatoid; Citrullination; Citrulline; Extracellular Traps; Humans; Ionomycin; Mice; Mice, Inbred DBA; Mice, Knockout; Neutrophils; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Tetradecanoylphorbol Acetate; Uric Acid | 2019 |
Characteristics of regulatory B10 cells in patients with rheumatoid arthritis with different disease status.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Arthritis, Rheumatoid; B-Lymphocytes, Regulatory; Case-Control Studies; CD40 Ligand; Cell Proliferation; Female; Gene Expression; Humans; Interleukin-10; Ionomycin; Lipopolysaccharides; Lymphocyte Activation; Lymphocyte Count; Male; Middle Aged; Primary Cell Culture; Recurrence; Severity of Illness Index; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2015 |
Nicotine drives neutrophil extracellular traps formation and accelerates collagen-induced arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cartilage; Dose-Response Relationship, Drug; Electronic Nicotine Delivery Systems; Enzyme-Linked Immunosorbent Assay; Extracellular Traps; Humans; Infusions, Subcutaneous; Male; Mice, Inbred DBA; Neutrophils; Nicotine; Nicotinic Agonists; Peroxidase; Smoking; Tetradecanoylphorbol Acetate | 2017 |
Inhibitory effect of triptolide on interleukin-18 and its receptor in rheumatoid arthritis synovial fibroblasts.
Topics: Animals; Arthritis, Rheumatoid; Cells, Cultured; Diterpenes; Epoxy Compounds; Fibroblasts; Humans; Immunosuppressive Agents; Interleukin-18; Phenanthrenes; Receptors, Interleukin-18; Synovial Membrane; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2008 |
TH-17 cells in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Carcinogens; Case-Control Studies; Cells, Cultured; Female; Humans; Interferon-gamma; Interleukin-17; Interleukin-23; Interleukins; Ionomycin; Ionophores; Leukocytes, Mononuclear; Macrophages; Male; Middle Aged; Osteoarthritis; RNA, Messenger; Synovial Fluid; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 2008 |
Proinflammatory and prothrombotic effects on human vascular endothelial cells of immune-cell-derived LIGHT.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cell Differentiation; Cells, Cultured; Drug Combinations; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression; Hepatitis C, Chronic; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Ionomycin; Leukocytes, Mononuclear; Macrophages; Middle Aged; Molecular Weight; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thromboplastin; Tumor Necrosis Factor Ligand Superfamily Member 14; Umbilical Veins; Up-Regulation; Young Adult | 2009 |
Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; CD4-Positive T-Lymphocytes; Cells, Cultured; Female; Hindlimb; Humans; Interleukin-17; Ionomycin; Joints; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Middle Aged; Receptors, Antigen, T-Cell, gamma-delta; Tetradecanoylphorbol Acetate | 2009 |
Quantification and phenotype of regulatory T cells in rheumatoid arthritis according to disease activity score-28.
Topics: Aged; Antigens, CD; Arthritis, Rheumatoid; CD4 Lymphocyte Count; CTLA-4 Antigen; Female; Forkhead Transcription Factors; Humans; Immunophenotyping; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-2 Receptor alpha Subunit; Ionomycin; Male; Middle Aged; Recurrence; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 2009 |
The CD14(bright) CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell population.
Topics: Arthritis, Rheumatoid; Cell Differentiation; Cell Separation; Coculture Techniques; Cytokines; Female; Flow Cytometry; HLA-DR Antigens; Humans; Ionomycin; Leukocyte Count; Lipopolysaccharide Receptors; Male; Middle Aged; Monocytes; Receptors, CCR5; Receptors, IgG; Tetradecanoylphorbol Acetate; Th17 Cells | 2012 |
Increased serum interleukin 22 in patients with rheumatoid arthritis and correlation with disease activity.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Calcium Ionophores; Carcinogens; Cells, Cultured; Disease Progression; Female; Humans; Interleukin-22; Interleukins; Ionomycin; Leukocytes, Mononuclear; Male; Middle Aged; Osteolysis; Rheumatoid Factor; Severity of Illness Index; Tetradecanoylphorbol Acetate | 2012 |
Anti-inflammatory and apoptotic effects of the polyphenol curcumin on human fibroblast-like synoviocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arthritis, Rheumatoid; Cell Line; Curcumin; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Interleukin-1beta; Interleukin-6; NF-kappa B; Polyphenols; Synovial Membrane; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2013 |
NF-kappaB-dependent lymphocyte hyperadhesiveness to synovial fibroblasts by hypoxia and reoxygenation: potential role in rheumatoid arthritis.
Topics: Antioxidants; Arthritis, Rheumatoid; Blotting, Western; Carcinogens; Cell Adhesion; Cells, Cultured; DNA Primers; Fibroblasts; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Lymphocytes; NF-kappa B; Oxygen; Pyrrolidines; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Thiocarbamates; Up-Regulation | 2003 |
Interleukin-18 is regulated by G protein pathways and protein kinase signals in human fibroblasts.
Topics: Arthritis, Rheumatoid; Cell Line, Transformed; Cells, Cultured; Cyclic AMP; Enzyme Inhibitors; Fibroblasts; GTP-Binding Proteins; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-18; Ionomycin; Microscopy, Electron, Scanning; Osteoarthritis; Peptides; Protein Kinase C; RNA, Messenger; Signal Transduction; Synovial Membrane; Tetradecanoylphorbol Acetate; Up-Regulation | 2004 |
Comparison of intracellular cytokine production with extracellular cytokine levels using two flow cytometric techniques.
Topics: Arthritis, Rheumatoid; CD3 Complex; Cells, Cultured; Cytokines; Extracellular Fluid; Flow Cytometry; Humans; Immunoassay; Intracellular Fluid; Lipopolysaccharide Receptors; Lipopolysaccharides; Microspheres; Monocytes; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2003 |
Impact of VIP and cAMP on the regulation of TNF-alpha and IL-10 production: implications for rheumatoid arthritis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Arthritis, Rheumatoid; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-10; Ionomycin; Lipopolysaccharides; Macrophages; Monocytes; Phosphodiesterase Inhibitors; Protein Kinase C; Rolipram; Synovial Membrane; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide | 2003 |
Differential effect of phosphodiesterase IV inhibitor RP73401 on various inflammatory and immune responses relevent to rheumatoid arthritis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arachidonic Acid; Arthritis, Experimental; Arthritis, Rheumatoid; Benzamides; Cell Physiological Phenomena; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Drug Evaluation, Preclinical; Ear Diseases; Edema; Humans; Immunity, Active; Inflammation; Lipopolysaccharides; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Nitric Oxide; Pyridines; Rats; Rats, Sprague-Dawley; Spleen; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2004 |
[Effects of PMA on CD147 expression in cultured THP-1 cells and monocytes of RA patients].
Topics: Arthritis, Rheumatoid; Basigin; Cell Culture Techniques; Cell Line; Cells, Cultured; Gene Expression; Humans; Monocytes; Tetradecanoylphorbol Acetate | 2006 |
A catalytically independent physiological function for human acute phase protein group IIA phospholipase A2: cellular uptake facilitates cell debris removal.
Topics: Acute-Phase Proteins; Amino Acid Substitution; Anions; Arthritis, Rheumatoid; Cell Line; Cell Nucleus; Gene Expression Regulation, Enzymologic; Group II Phospholipases A2; Heparan Sulfate Proteoglycans; Humans; Hydrolysis; Inflammation; Mutation, Missense; Phospholipids; Pinocytosis; Protein Binding; Protein Transport; Synovial Fluid; Tetradecanoylphorbol Acetate; Transport Vesicles; Wounds and Injuries | 2008 |
Human CD4(+) T cells maintain specific functions even under conditions of extremely restricted ATP production.
Topics: Adenosine Triphosphate; Arthritis, Rheumatoid; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; CD4-Positive T-Lymphocytes; Cell Proliferation; Cytochromes b; Cytokines; Electron Transport Complex III; Gene Expression; Gene Expression Profiling; Glucose; Glycolysis; Humans; Hypoxia; Ionomycin; Joint Capsule; Lymphocyte Activation; Methacrylates; Osteoarthritis; Oxidative Phosphorylation; Oxygen Consumption; Tetradecanoylphorbol Acetate; Thiazoles | 2008 |
Effect of antiinflammatory agents on neutrophil superoxide production in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Humans; Indomethacin; Neutrophils; Opsonin Proteins; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1984 |
Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis.
Topics: Arthritis, Rheumatoid; Bacterial Toxins; Base Sequence; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Endothelial Growth Factors; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1; Lymphokines; Molecular Sequence Data; Neovascularization, Pathologic; Prostaglandins E; Protein Kinase C; Receptors, Prostaglandin E; Signal Transduction; Synovial Fluid; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1995 |
High level of interleukin-10 production by the activated T cell population within the rheumatoid synovial membrane.
Topics: Adult; Arthritis, Rheumatoid; Cells, Cultured; Female; Humans; Immunohistochemistry; Interferon-gamma; Interleukin-10; Interleukin-2; Interleukin-4; Lymphocyte Activation; Middle Aged; Phenotype; Synovial Membrane; T-Lymphocytes; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells | 1995 |
Immobilized anti-CD3 antibody activates T cell clones to induce the production of interstitial collagenase, but not tissue inhibitor of metalloproteinases, in monocytic THP-1 cells and dermal fibroblasts.
Topics: Aged; Antibodies, Monoclonal; Arthritis, Rheumatoid; CD3 Complex; Cell Communication; Clone Cells; Collagenases; Cytotoxicity Tests, Immunologic; Female; Fibroblasts; Flow Cytometry; Glycoproteins; Humans; Lymphocyte Activation; Male; Matrix Metalloproteinase 1; Middle Aged; Monocytes; Osteoarthritis; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases | 1995 |
Receptor expression in synovial fluid neutrophils from patients with rheumatoid arthritis.
Topics: Antigens, CD; Arthritis, Rheumatoid; CD11 Antigens; Cells, Cultured; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Male; Neutrophils; Receptors, Complement 3b; Receptors, IgG; Receptors, Immunologic; Synovial Fluid; Tetradecanoylphorbol Acetate | 1993 |
Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Cells, Cultured; Humans; Immunohistochemistry; Interleukin-1; Isoenzymes; Precipitin Tests; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate | 1994 |
Increased expression of VLA-5 adhesion molecules on synovial fluid T lymphocytes in chronic polyarthritis: a consequence of T-cell activation.
Topics: Adult; Aged; Arthritis, Reactive; Arthritis, Rheumatoid; Concanavalin A; HLA-DR Antigens; Humans; Lymphocyte Activation; Middle Aged; Receptors, Fibronectin; Synovial Fluid; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1994 |
[Impaired function of polymorphonuclear neutrophilic granulocytes in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Blood Bactericidal Activity; Humans; In Vitro Techniques; Neutrophils; Osteoarthritis; Phagocytosis; Respiratory Burst; Tetradecanoylphorbol Acetate | 1993 |
Differential expression of gelatinase B (MMP-9) and stromelysin-1 (MMP-3) by rheumatoid synovial cells in vitro and in vivo.
Topics: Arthritis, Rheumatoid; Blotting, Western; Cells, Cultured; Collagenases; Fibroblasts; Gene Expression; Humans; Immunohistochemistry; Interleukin-1; Macrophages; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Metalloendopeptidases; Phenotype; Synovial Membrane; Tetradecanoylphorbol Acetate | 1993 |
The C1q binding activity of IgG is modified in vitro by reactive oxygen species: implications for rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Complement Activation; Complement C1q; Copper; Gamma Rays; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunoglobulin G; Middle Aged; Reactive Oxygen Species; Superoxides; Synovial Fluid; Tetradecanoylphorbol Acetate | 1996 |
Leflunomide, a novel immunomodulating drug, inhibits homotypic adhesion of mononuclear cells in rheumatoid arthritis.
Topics: Antigens, CD; Arthritis, Rheumatoid; Cell Aggregation; Cells, Cultured; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lymphocytes; Synovial Fluid; Tetradecanoylphorbol Acetate | 1996 |
Interleukin-4 inhibits the gene expression and biosyntheis of cytosolic phospholipase A2 in lipopolysaccharide stimulated U937 macrophage cell line and freshly prepared adherent rheumatoid synovial cells.
Topics: Arthritis, Rheumatoid; Cell Adhesion; Cell Differentiation; Cell Line; Cytosol; Enzyme Induction; Gene Expression Regulation, Enzymologic; Humans; Interleukin-4; Knee Prosthesis; Lipopolysaccharides; Lymphoma, Large B-Cell, Diffuse; Macrophages; Phospholipases A; Phospholipases A2; Polymerase Chain Reaction; Recombinant Proteins; Synovial Membrane; Tetradecanoylphorbol Acetate | 1997 |
Characterization of a SV40-transformed rheumatoid synovial fibroblast cell line which retains genotypic expression patterns: a model for evaluation of anti-arthritic agents.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cell Line, Transformed; Dexamethasone; Fibroblasts; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Genes, jun; Genotype; Humans; Interleukin-1; Metalloendopeptidases; Models, Biological; Simian virus 40; Synovial Membrane; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1997 |
CD44 expression by leucocytes in rheumatoid arthritis and modulation by specific antibody: implications for lymphocyte adhesion to endothelial cells and synoviocytes in vitro.
Topics: Antibodies, Monoclonal; Arthritis, Rheumatoid; Cell Adhesion; Cells, Cultured; Endothelium; Fibroblasts; Flow Cytometry; Granulocytes; Humans; Hyaluronan Receptors; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocytes; Metalloendopeptidases; Serine; Synovial Fluid; Synovial Membrane; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Rheumatoid synovial fibroblasts are stimulated by the cellular adhesion to T cells through lymphocyte function associated antigen-1/intercellular adhesion molecule-1.
Topics: Arthritis, Rheumatoid; Cell Adhesion; Cell Line; Fibroblasts; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; RNA, Messenger; Synovial Membrane; Synovitis; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells.
Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Antigens, CD; Arthritis, Rheumatoid; B7-1 Antigen; CD58 Antigens; Cell Adhesion Molecules; Cells, Cultured; Clarithromycin; Cytokines; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; HLA-DR Antigens; Humans; Immunoenzyme Techniques; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-1; Interleukin-10; Interleukin-6; Interleukin-8; Lymphocyte Activation; Osteoarthritis; Synovial Membrane; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tuberculin; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 1996 |
Phorbol 12-myristate 13-acetate (PMA)-induced oxyradical production in rheumatoid synovial cells.
Topics: Arthritis, Rheumatoid; Calcium; Carcinogens; Catalase; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fibroblasts; Humans; Hydrogen Peroxide; Knee Joint; Luminescent Measurements; Macrophages; Naphthalenes; Photons; Protein Kinase C; Superoxide Dismutase; Superoxides; Synovial Fluid; Tetradecanoylphorbol Acetate | 1997 |
Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: a mechanism for methotrexate-induced nodulosis in rheumatoid arthritis.
Topics: Adenosine; Antirheumatic Agents; Arthritis, Rheumatoid; Cells, Cultured; Humans; Methotrexate; Monocytes; Receptors, Purinergic P1; Rheumatoid Nodule; Tetradecanoylphorbol Acetate; Theobromine; Xanthines | 1997 |
Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells. Regulation by tumor necrosis factor-alpha and doxycycline.
Topics: Arthritis, Rheumatoid; Catalysis; Cells, Cultured; Collagenases; Doxycycline; Endothelium; Endothelium, Vascular; Enzyme Inhibitors; Fibroblasts; Glycosylation; Humans; Matrix Metalloproteinase 8; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation | 1997 |
Induction and expression of human cartilage glycoprotein 39 in rheumatoid inflammatory and peripheral blood monocyte-derived macrophages.
Topics: Adipokines; Arthritis, Rheumatoid; Cartilage, Articular; Cell Differentiation; Cell Line; Cells, Cultured; Chitinase-3-Like Protein 1; Cholecalciferol; Cycloheximide; Glycoproteins; HL-60 Cells; Humans; Inflammation; Jurkat Cells; Kinetics; Lectins; Macrophages; Monocytes; Polymerase Chain Reaction; Recombinant Proteins; Reference Values; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
ATP and UTP activate calcium-mobilizing P2U-like receptors and act synergistically with interleukin-1 to stimulate prostaglandin E2 release from human rheumatoid synovial cells.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Buffers; Calcium; Dinoprostone; Drug Synergism; Humans; Interleukin-1; Middle Aged; Purinergic Agonists; Receptors, Purinergic; Synovial Membrane; Tetradecanoylphorbol Acetate; Thapsigargin; Uridine Triphosphate | 1998 |
Tachykinin receptors are present on human monocytes and play a role in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Cell Separation; Female; Humans; Male; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin A; Neurokinin B; Peptide Fragments; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Rheumatoid synovial endothelial cells secrete decreased levels of tissue inhibitor of MMP (TIMP1).
Topics: Arthritis, Rheumatoid; Blotting, Western; Cells, Cultured; Collagenases; Electrophoresis, Polyacrylamide Gel; Endothelium; Enzyme-Linked Immunosorbent Assay; Gelatinases; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metalloendopeptidases; Skin; Spectrophotometry; Synovial Membrane; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1 | 1998 |
Interleukin-1alpha and tumor necrosis factor alpha synergistically stimulate prostaglandin E2-dependent production of interleukin-11 in rheumatoid synovial fibroblasts.
Topics: Arthritis, Rheumatoid; Carcinogens; Cells, Cultured; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Indoles; Interleukin-1; Interleukin-11; Isoquinolines; Maleimides; Protein Kinase C; Signal Transduction; Sulfonamides; Synovial Membrane; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Synovial PMN show a coordinated up-regulation of CD66 molecules.
Topics: Adult; Aged; Alprostadil; Antigens, CD; Antigens, Differentiation; Arthritis; Arthritis, Psoriatic; Arthritis, Reactive; Arthritis, Rheumatoid; CD59 Antigens; Cell Adhesion Molecules; Dinoprostone; Female; Flow Cytometry; Gene Expression Regulation; Glycosylphosphatidylinositols; Humans; L-Selectin; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Isoforms; Receptors, IgG; Synovial Fluid; Tetradecanoylphorbol Acetate | 1999 |
Lymphocyte stimulation by CD3-CD28 enables detection of low T cell interferon-gamma and interleukin-4 production in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; CD28 Antigens; CD3 Complex; Humans; Interferon-gamma; Interleukin-4; Ionomycin; Lymphocyte Activation; Statistics, Nonparametric; T-Lymphocytes; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells | 1999 |
Detection of human soluble Thy-1 in serum by ELISA. Fibroblasts and activated endothelial cells are a possible source of soluble Thy-1 in serum.
Topics: Arthritis, Rheumatoid; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Male; Melanoma; Platelet Endothelial Cell Adhesion Molecule-1; Recombinant Proteins; Skin; Skin Neoplasms; Synovial Membrane; Tetradecanoylphorbol Acetate; Thy-1 Antigens; Tumor Necrosis Factor-alpha; Varicose Ulcer | 1999 |
The relative proportions of secreted interleukin-2 and interleukin-10 determine the magnitude of rheumatoid arthritis T-cell proliferation to the recall antigen tuberculin purified protein derivative.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cell Division; Female; Humans; Interleukin-10; Interleukin-2; Ionomycin; Leukocytes, Mononuclear; Male; Middle Aged; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tuberculin | 1999 |
High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cell Separation; Cells, Cultured; Cyclosporine; Humans; Interleukin-15; Interleukin-17; Interleukin-2; Ionomycin; Leukocytes, Mononuclear; Methylprednisolone; Middle Aged; Osteoarthritis; Phytohemagglutinins; Synovial Fluid; Tetradecanoylphorbol Acetate | 2000 |
Study of eosinophil-endothelial adhesion, production of oxygen radicals and release of eosinophil cationic protein by peripheral blood eosinophils of patients with rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Autoimmune Diseases; Blood Proteins; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Inflammation; Interleukin-1; Macrophage-1 Antigen; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Ribonucleases; Tetradecanoylphorbol Acetate; Umbilical Cord | 1993 |
Cell-cell contact between lymphocytes and fibroblast-like synoviocytes induces lymphocytic expression of aminopeptidase N/CD13 and results in lymphocytic activation.
Topics: Arthritis, Rheumatoid; Blotting, Western; CD13 Antigens; Cell Communication; Cell Movement; Coculture Techniques; Collagen; Cytochalasin B; Fibroblasts; Fluorescent Antibody Technique, Indirect; Gels; Gene Expression Profiling; Humans; Ionomycin; Jurkat Cells; Lymphocyte Activation; MAP Kinase Signaling System; Microscopy, Confocal; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stromal Cells; Synovial Fluid; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2000 |
Is lymphocyte histamine involved in the pathogenesis of rheumatoid arthritis?
Topics: Aged; Arthritis, Rheumatoid; Female; Histamine; Histamine Release; Humans; Lymphocytes; Male; Middle Aged; Phytohemagglutinins; Tetradecanoylphorbol Acetate | 2000 |
Spontaneous and cytokine regulated c-fos gene expression in rheumatoid synovial cells: resistance to cytokine stimulation when the c-fos gene is overexpressed.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Genes, fos; Genes, ras; Humans; Interleukin-6; Promoter Regions, Genetic; Synovial Membrane; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2000 |
CD97 isoform expression in leukocytes.
Topics: Antigens, CD; Antigens, Neoplasm; Arthritis, Rheumatoid; CD55 Antigens; Cell Adhesion; Cells, Cultured; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Interferon-gamma; Jurkat Cells; K562 Cells; Leukocytes; Membrane Glycoproteins; Molecular Weight; Polymerase Chain Reaction; Protein Isoforms; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; RNA, Messenger; RNA, Neoplasm; Synovial Fluid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; U937 Cells | 2000 |
Induction of collagenase-3 (MMP-13) in rheumatoid arthritis synovial fibroblasts.
Topics: Antibodies; Arthritis, Rheumatoid; Base Sequence; Blotting, Western; Collagenases; Cytokines; DNA Primers; Enzyme Induction; Fibroblasts; Humans; Immunohistochemistry; In Vitro Techniques; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Microscopy, Fluorescence; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases | 2000 |
Cartilage degradation by stimulated human neutrophils: reactive oxygen species decrease markedly the activity of proteolytic enzymes.
Topics: Animals; Arthritis, Rheumatoid; Biphenyl Compounds; Cartilage, Articular; Culture Media, Conditioned; Cytochalasin B; Endopeptidases; Humans; In Vitro Techniques; Luminescent Measurements; Magnetic Resonance Spectroscopy; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Onium Compounds; Proteoglycans; Reactive Oxygen Species; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tetradecanoylphorbol Acetate | 2000 |
Tachykinin activation of human monocytes from patients with rheumatoid arthritis: in vitro and ex-vivo effects of cyclosporin A.
Topics: Arthritis, Rheumatoid; Carcinogens; Cells, Cultured; Cyclosporine; Humans; Immunosuppressive Agents; In Vitro Techniques; Monocytes; Neurokinin A; Peptide Fragments; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Respiratory Burst; Substance P; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Presence of a population of CD20+, CD38- B lymphocytes with defective proliferative responsiveness in the synovial compartment of patients with rheumatoid arthritis.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Adult; Aged; Antigens, CD; Antigens, CD20; Antigens, Differentiation; Arthritis, Rheumatoid; B-Lymphocytes; Calcium Signaling; Carcinogens; CD40 Antigens; CD40 Ligand; Cell Division; Cells, Cultured; Female; Humans; Immunoglobulins; Interleukin-10; Interleukin-2; Ionomycin; Ionophores; Male; Membrane Glycoproteins; Middle Aged; NAD+ Nucleosidase; Oxidation-Reduction; Synovial Fluid; Synovial Membrane; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2001 |
Secretion of gelatinases and activation of gelatinase A (MMP-2) by human rheumatoid synovial fibroblasts.
Topics: Arthritis, Rheumatoid; Concanavalin A; Cyclic CMP; Cytochalasin D; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gelatinases; Humans; Indomethacin; Ionophores; Matrix Metalloproteinase 2; Pentoxifylline; Protein Kinase Inhibitors; Synovial Fluid; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Vanadates | 2001 |
Regulation of 1 alpha, 25-dihydroxyvitamin D3 synthesis in macrophages from arthritic joints by phorbol ester, dibutyryl-cAMP and calcium ionophore (A23187).
Topics: Arthritis; Arthritis, Gouty; Arthritis, Rheumatoid; Bucladesine; Calcimycin; Calcitriol; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Macrophages; Synovial Fluid; Tetradecanoylphorbol Acetate | 1992 |
Effect of staurosporine derivatives on IL-1-stimulated prostaglandin E production.
Topics: Alkaloids; Arthritis, Rheumatoid; Cells, Cultured; Fibroblasts; Humans; Interleukin-2; Kinetics; Prostaglandins E; Protein Kinase C; Staurosporine; Structure-Activity Relationship; Synovial Fluid; Tetradecanoylphorbol Acetate | 1992 |
Expression of stromelysin and stromelysin-2 in rabbit and human fibroblasts.
Topics: Animals; Arthritis, Rheumatoid; Base Sequence; Cells, Cultured; Consensus Sequence; Dexamethasone; Enzyme Induction; Enzyme Precursors; Fibroblasts; Glycoproteins; Humans; Infant, Newborn; Male; Matrix Metalloproteinase 10; Matrix Metalloproteinase 3; Metalloendopeptidases; Molecular Sequence Data; Penis; Proto-Oncogene Proteins c-jun; Rabbits; Recombinant Fusion Proteins; Sequence Homology, Nucleic Acid; Synovial Fluid; Tetradecanoylphorbol Acetate; Tretinoin | 1992 |
Differential effects of IL-1 and TNF alpha on the expression of stromelysin, collagenase and their natural inhibitor, TIMP, in rheumatoid human synovial fibroblasts.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Collagenases; Enzyme Induction; Fibroblasts; Gene Expression Regulation; Glycoproteins; Humans; Interleukin-1; Matrix Metalloproteinase 3; Metalloendopeptidases; Recombinant Proteins; Synovial Fluid; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Tumor Necrosis Factor-alpha | 1992 |
Ligand dependent release of activated neutrophil collagenase--a role for surface bound IgG in the degradation of articular collagens.
Topics: Arthritis, Rheumatoid; Cartilage, Articular; Collagenases; Humans; Immunoglobulin G; Ligands; Matrix Metalloproteinase 8; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Antigen, B-Cell; Synovial Fluid; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Effect of fish oil on neutrophil chemiluminescence induced by different stimuli in patients with rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Fatty Acids, Omega-3; Female; Humans; Luminescent Measurements; Middle Aged; Neutrophils; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1992 |
Diclofenac inhibits monocyte superoxide production ex vivo in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Diclofenac; Female; Fluorides; Humans; Middle Aged; Monocytes; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Collagenase reserves in polymorphonuclear neutrophil leukocytes from synovial fluid and peripheral blood of patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Cells; Collagen; Humans; Microbial Collagenase; Neutrophils; Synovial Fluid; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Neutrophil chemiluminescence and superoxide production in patients with rheumatoid arthritis: the effect of zymosan, phorbol myristate acetate and platelet-activating factor.
Topics: Arthritis, Rheumatoid; Humans; Luminescent Measurements; Neutrophils; Platelet Activating Factor; Superoxides; Synovial Fluid; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Discoordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinases-1 in rheumatoid human synovial fibroblasts. Synergistic effects of interleukin-1 and tumor necrosis factor-alpha on stromelysin expression.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Cloning, Molecular; DNA; Drug Synergism; Fibroblasts; Glycoproteins; Humans; Interleukin-1; Kinetics; Matrix Metalloproteinase 3; Metalloendopeptidases; Microbial Collagenase; RNA; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1990 |
Neutrophils isolated from the synovial fluid of patients with rheumatoid arthritis: priming and activation in vivo.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cytochalasin B; Humans; Luminescent Measurements; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Peroxidase; Stimulation, Chemical; Synovial Fluid; Tetradecanoylphorbol Acetate | 1991 |
Retinoids and rheumatoid arthritis: modulation of extracellular matrix by controlling expression of collagenase.
Topics: Animals; Arthritis, Rheumatoid; Cells, Cultured; Collagen; Dexamethasone; Enzyme Activation; Extracellular Matrix; Humans; Kinetics; Nucleic Acid Hybridization; Rabbits; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin | 1990 |
Superoxide anion production by circulating polymorphonuclear leucocytes in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cytochrome c Group; Female; Hot Temperature; Humans; Male; Middle Aged; Neutrophils; Osteoarthritis; Oxidation-Reduction; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Activation pathways of synovial T lymphocytes. Expression and function of the UM4D4/CDw60 antigen.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Arthritis, Rheumatoid; Female; Humans; Lymphocyte Activation; Male; Middle Aged; Receptors, Interleukin-2; Synovial Fluid; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Low levels of interleukin-4 and high levels of transforming growth factor beta in rheumatoid synovitis.
Topics: Antibodies; Arthritis, Rheumatoid; Cell Division; Humans; Interleukin-4; Lymphocyte Activation; Lymphocytes; Synovial Fluid; Synovitis; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1990 |
A functional study of purified CD4+ and CD8+ cells isolated from synovial fluid of patients with rheumatoid arthritis and other arthritides.
Topics: Adult; Aged; Antigens, Differentiation, T-Lymphocyte; Arthritis; Arthritis, Rheumatoid; CD8 Antigens; Female; Humans; Interleukin-2; Lymphocyte Activation; Male; Middle Aged; Synovial Fluid; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Characterization of the IL-2-receptor on rheumatoid arthritis synovial fluid T cells.
Topics: Adult; Aged; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Arthritis, Rheumatoid; CD3 Complex; Cell Division; Cell Separation; Cross-Linking Reagents; Flow Cytometry; Humans; Interleukin-2; Middle Aged; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; Recombinant Proteins; Synovial Fluid; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamethasone.
Topics: Animals; Arthritis, Rheumatoid; Base Sequence; Cholera Toxin; Cyclic AMP; Dexamethasone; Epidermal Growth Factor; Gene Expression Regulation; Interleukin-1; Matrix Metalloproteinase 3; Metalloendopeptidases; Molecular Sequence Data; Neoplasm Invasiveness; Promoter Regions, Genetic; Rabbits; Repetitive Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Wound Healing | 1987 |
Enhanced oxidative response of polymorphonuclear leukocytes from synovial fluids of patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Carboxypeptidases; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Male; Middle Aged; Neutrophils; Oxidation-Reduction; Superoxides; Synovial Fluid; Tetradecanoylphorbol Acetate | 1988 |
Abnormal lymphocyte reactivity to self-major histocompatibility antigens in rheumatoid arthritis.
Topics: Adult; Aged; Antibodies, Monoclonal; Arthritis, Rheumatoid; Humans; Lymphocyte Culture Test, Mixed; Major Histocompatibility Complex; Middle Aged; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tuberculin | 1987 |
Self-perpetuating mechanisms of immunoglobulin G aggregation in rheumatoid inflammation.
Topics: Adult; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Immunologic; Free Radicals; Humans; Immunoglobulin G; Middle Aged; Neutrophils; Protein Binding; Spectrometry, Fluorescence; Superoxides; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1985 |
Superoxide production by polymorphonuclear leucocytes in rheumatoid arthritis and osteoarthritis: in vivo inhibition by the antirheumatic drug piroxicam due to interference with the activation of the NADPH-oxidase.
Topics: Arthritis; Arthritis, Rheumatoid; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Osteoarthritis; Piroxicam; Superoxides; Tetradecanoylphorbol Acetate; Thiazines | 1986 |
Oxygen radical production by neutrophils from patients with bacterial infection and rheumatoid arthritis. Measurement of hydrogen peroxide may most accurately represent enhancement of oxygen radical production during infection.
Topics: Arthritis, Rheumatoid; Bacterial Infections; C-Reactive Protein; Calcimycin; Cytochalasin B; Free Radicals; Humans; Hydrogen Peroxide; Leukocyte Count; Neutrophils; Oxygen; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Deficiency of neutrophil membrane antigen detected by monoclonal antibody in rheumatoid arthritis.
Topics: Antibodies, Monoclonal; Antigens, Surface; Arthritis, Rheumatoid; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Altered function of synovial fluid granulocytes in patients with acute inflammatory arthritis: evidence for activation of neutrophils and its mediation by a factor present in synovial fluid.
Topics: Acute Disease; Arthritis, Rheumatoid; Humans; In Vitro Techniques; Kinetics; Luminescent Measurements; Neutrophils; Superoxides; Synovial Fluid; Synovitis; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
[Expression of T-lymphocyte antigens by serum B lymphocytes in rheumatoid polyarthritis].
Topics: Adult; Aged; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Arthritis, Rheumatoid; B-Lymphocytes; Female; Herpesvirus 4, Human; Humans; Lymphocyte Activation; Male; Middle Aged; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
CD5 positive B cells in patients with rheumatoid arthritis: phorbol ester mediated enhancement of detection.
Topics: Adult; Aged; Antigens, Differentiation, B-Lymphocyte; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Arthritis, Rheumatoid; B-Lymphocytes; Cells, Cultured; Female; Fluorescent Antibody Technique; Growth Substances; Humans; Interleukin-4; Lymph Nodes; Lymphokines; Male; Middle Aged; Palatine Tonsil; Spleen; Tetradecanoylphorbol Acetate | 1987 |
Impaired mitogen-induced interferon-gamma production in rheumatoid arthritis and related diseases.
Topics: Adolescent; Adult; Aged; Arthritis, Reactive; Arthritis, Rheumatoid; Autoimmune Diseases; Calcimycin; Drug Synergism; Humans; Interferon-gamma; Lectins; Lupus Erythematosus, Systemic; Lymphocyte Activation; Middle Aged; Osteoarthritis; Receptors, Immunologic; Receptors, Interleukin-2; Scleroderma, Systemic; Tetradecanoylphorbol Acetate | 1988 |
Regulation of interleukin-2 production in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cell Line; Female; Humans; Indomethacin; Interleukin-2; Lymphocytes; Male; Middle Aged; Synovial Fluid; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1987 |
Structural correlations of phorbol-ester-induced stimulation of PGE2 production by human rheumatoid synovial cells.
Topics: Arthritis, Rheumatoid; Dinoprostone; Humans; Phorbol Esters; Phorbols; Prostaglandins E; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1985 |