cyproheptadine has been researched along with Rheumatoid Arthritis in 4 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Investigating the efficacy and safety of rupatadine (RUP) versus montelukast (MON) as adjuvant therapy for patients with rheumatoid arthritis (RA)." | 5.41 | Comparative study evaluating antihistamine versus leukotriene receptor antagonist as adjuvant therapy for rheumatoid arthritis. ( El-Ghany, SEA; Hegazy, SK; Kotkata, FAE; Mostafa, TM, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mostafa, TM | 1 |
| Hegazy, SK | 1 |
| El-Ghany, SEA | 1 |
| Kotkata, FAE | 1 |
| MOENS, C | 1 |
| Rosenberg, JM | 1 |
| Kirschenbaum, HL | 1 |
| Saleem, G | 1 |
| Ritz, J | 1 |
| Martino, FP | 1 |
| Hirschelmann, R | 1 |
| Bekemeier, H | 1 |
| Metzner, J | 1 |
| Giessler, AJ | 1 |
| Stelzner, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study Evaluating the Effect of Histamine 1 Receptor Antagonist and Leukotreine Receptor Antagonist on Patients With Rheumatoid Arithritis[NCT03770923] | Phase 3 | 75 participants (Anticipated) | Interventional | 2018-10-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for cyproheptadine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Comparative study evaluating antihistamine versus leukotriene receptor antagonist as adjuvant therapy for rheumatoid arthritis.
Topics: Acetates; Adult; Arthritis, Rheumatoid; Body Mass Index; C-Reactive Protein; Clusterin; Cyclopropane | 2021 |
3 other studies available for cyproheptadine and Rheumatoid Arthritis
| Article | Year |
|---|---|
THE EFFECT OF ANTISEROTONIN AND DEXAMETHASONE IN THE TREATMENT OF RHEUMATOID ARTHRITIS.
Topics: Arthritis; Arthritis, Rheumatoid; Biomedical Research; Blood Sedimentation; Cyproheptadine; Dexameth | 1964 |
Benoxaprofen and cyproheptadine.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Child; Child, Preschool; Cyprohe | 1982 |
[Modification of the adjuvans arthritis by carrageenin, compound 48/80, histamine- and serotonin antagonists, non-steroid antiphlogistics as well as protease inhibitors and their possible relations to inflammation mediators].
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carrageenan; Chlorpromazine; Cyproheptadin | 1975 |