theobromine has been researched along with Rheumatoid Arthritis in 1 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine why methotrexate (MTX) exacerbates rheumatoid nodules in some patients, despite the effective suppression of synovial inflammation." | 7.69 | Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: a mechanism for methotrexate-induced nodulosis in rheumatoid arthritis. ( Coffey, D; Cronstein, BN; Fisher, R; Lahita, RG; Merrill, JT; Salmon, J; Schreibman, D; Shen, C; Zakharenko, O, 1997) |
| "To determine why methotrexate (MTX) exacerbates rheumatoid nodules in some patients, despite the effective suppression of synovial inflammation." | 3.69 | Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: a mechanism for methotrexate-induced nodulosis in rheumatoid arthritis. ( Coffey, D; Cronstein, BN; Fisher, R; Lahita, RG; Merrill, JT; Salmon, J; Schreibman, D; Shen, C; Zakharenko, O, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Merrill, JT | 1 |
| Shen, C | 1 |
| Schreibman, D | 1 |
| Coffey, D | 1 |
| Zakharenko, O | 1 |
| Fisher, R | 1 |
| Lahita, RG | 1 |
| Salmon, J | 1 |
| Cronstein, BN | 1 |
1 other study available for theobromine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: a mechanism for methotrexate-induced nodulosis in rheumatoid arthritis.
Topics: Adenosine; Antirheumatic Agents; Arthritis, Rheumatoid; Cells, Cultured; Humans; Methotrexate; Monoc | 1997 |