Page last updated: 2024-12-07

noracycline

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Noracycline: contains lynestrenol & mestranol [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID82149
MeSH IDM0043465

Synonyms (15)

Synonym
ovariostat
ovariostat [french]
19-norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-methoxy-, (17alpha)-, mixt. with (17alpha)-19-norpregn-4-en-20-yn-17-ol
sistometrenol
ovanon
noracycline
lyndiol
lynestrenol-mestranol
restovar
ccris 7260
8015-14-3
noracyclin
(8r,9s,13s,14s,17r)-3-ethyl-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-ol;(8r,9s,10r,13s,14s,17r)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1h-cyclopenta[a]phenanthren-17-ol
19-norpregn-4-en-20-yn-17-ol--3-ethyl-19-norpregna-1,3,5(10)-trien-20-yn-17-ol (1/1)
DTXSID801000994

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" The pathophysiology of this almost fatal drug reaction is described as a pharmacokinetic interaction: the inherent hepatotoxicity of prothionamide-the drug finally prescribed during convalescence-was significantly potentiated by the Cyt-P-450-inducing effect of the progestagen component of the hormonal contraceptive."( [Fulminant liver failure in tuberculostatic therapy. A contribution to clinical aspects and pharmacokinetics].
Bülau, P; Köster, O; Lelbach, WK; Musch, E; Stiens, R, 1987
)
0.27

Dosage Studied

ExcerptRelevanceReference
" In women pituitary suppressed by a high-dose oral contraceptive, the daily administration of 150 IU rFSH for 1 week induced more and larger antral follicles than the same regimen with urinary FSH, whereas the serum immunoactive FSH concentrations measured 24 h after each dosing were similar."( Clinical profiling of recombinant follicle stimulating hormone (rFSH; Puregon): relationship between serum FSH and efficacy.
Coelingh Bennink, H; Mannaerts, BM; Out, HJ; Rombout, F,
)
0.13
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (27)

TimeframeStudies, This Drug (%)All Drugs %
pre-199018 (66.67)18.7374
1990's8 (29.63)18.2507
2000's1 (3.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 10.41

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index10.41 (24.57)
Research Supply Index3.61 (2.92)
Research Growth Index4.02 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (10.41)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials4 (12.50%)5.53%
Reviews1 (3.13%)6.00%
Case Studies9 (28.13%)4.05%
Observational0 (0.00%)0.25%
Other18 (56.25%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]