Page last updated: 2024-10-26

dipyridamole and Rheumatoid Arthritis

dipyridamole has been researched along with Rheumatoid Arthritis in 9 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
" Dipyridamole inhibits the cellular uptake and metabolism of adenosine and we have, therefore, examined the effects of dipyridamole in patients with rheumatoid arthritis in an attempt to alleviate their symptoms."9.12Adenosine and cytokine levels following treatment of rheumatoid arthritis with dipyridamole. ( Darlington, LG; Forrest, CM; Harman, G; Mackay, GM; Oxford, L; Stone, TW; Stoy, N, 2006)
" Since the vascular protective drug dipyridamole inhibits the uptake and metabolism of adenosine we have now tested this compound in patients with rheumatoid arthritis to assess its effects on their symptoms."9.12Purine metabolism and clinical status of patients with rheumatoid arthritis treated with dipyridamole. ( Darlington, LG; Forrest, CM; Harman, G; Mackay, GM; Oxford, L; Stone, TW; Stoy, N, 2006)
"Dipyridamole Thallium-201 (T1) scintigraphic studies to evaluate microcirculation of the heart were performed in 54 patients with rheumatoid arthritis (RA) who had neither cardiac complaints nor myocardial damages on ECG."7.69[Detection of myocardial lesions by dipyridamole thallium-201 scintigraphy in patients with rheumatoid arthritis]. ( Momose, S, 1995)
"To assess red blood cell deformability (RCD) in patients with rheumatoid arthritis (RA) without extraarticular manifestations and in RA with vasculitic complications (RV), and to assess whether in vitro dipyridamole improves RCD."7.69Reduced red blood cell deformability in patients with rheumatoid vasculitis. Improvement after in vitro treatment with dipyridamole. ( Belch, JJ; Lau, CS; Saniabadi, AR, 1995)
" Dipyridamole inhibits the cellular uptake and metabolism of adenosine and we have, therefore, examined the effects of dipyridamole in patients with rheumatoid arthritis in an attempt to alleviate their symptoms."5.12Adenosine and cytokine levels following treatment of rheumatoid arthritis with dipyridamole. ( Darlington, LG; Forrest, CM; Harman, G; Mackay, GM; Oxford, L; Stone, TW; Stoy, N, 2006)
" Since the vascular protective drug dipyridamole inhibits the uptake and metabolism of adenosine we have now tested this compound in patients with rheumatoid arthritis to assess its effects on their symptoms."5.12Purine metabolism and clinical status of patients with rheumatoid arthritis treated with dipyridamole. ( Darlington, LG; Forrest, CM; Harman, G; Mackay, GM; Oxford, L; Stone, TW; Stoy, N, 2006)
"Dipyridamole Thallium-201 (T1) scintigraphic studies to evaluate microcirculation of the heart were performed in 54 patients with rheumatoid arthritis (RA) who had neither cardiac complaints nor myocardial damages on ECG."3.69[Detection of myocardial lesions by dipyridamole thallium-201 scintigraphy in patients with rheumatoid arthritis]. ( Momose, S, 1995)
"To assess red blood cell deformability (RCD) in patients with rheumatoid arthritis (RA) without extraarticular manifestations and in RA with vasculitic complications (RV), and to assess whether in vitro dipyridamole improves RCD."3.69Reduced red blood cell deformability in patients with rheumatoid vasculitis. Improvement after in vitro treatment with dipyridamole. ( Belch, JJ; Lau, CS; Saniabadi, AR, 1995)
" There seems to be a boost and extension of the glucocorticoid effect by the combination, without a clear increase of adverse effects, potentially allowing the application of lower dosages."1.35Innovative combination strategy to enhance effect and diminish adverse effects of glucocorticoids: another promise? ( Bijlsma, JW; Jacobs, JW, 2009)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's2 (22.22)18.2507
2000's6 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobs, JW1
Bijlsma, JW1
Turiel, M1
Atzeni, F1
Tomasoni, L1
de Portu, S1
Delfino, L1
Bodini, BD1
Longhi, M1
Sitia, S1
Bianchi, M1
Ferrario, P1
Doria, A1
De Gennaro Colonna, V1
Sarzi-Puttini, P1
Riksen, NP1
Barrera, P1
van den Broek, PH1
van Riel, PL1
Smits, P1
Rongen, GA1
Forrest, CM2
Stoy, N2
Stone, TW2
Harman, G2
Mackay, GM2
Oxford, L2
Darlington, LG2
Momose, S1
Lau, CS1
Saniabadi, AR1
Belch, JJ1
Baron, BW1
Martin, MS1
Sucharetza, BS1
Jeon, H1
Baron, JM1
Vogel, G1
Krusch, G1

Reviews

1 review available for dipyridamole and Rheumatoid Arthritis

ArticleYear
Four patients with both thrombotic thrombocytopenic purpura and autoimmune thrombocytopenic purpura: the concept of a mixed immune thrombocytopenia syndrome and indications for plasma exchange.
    Journal of clinical apheresis, 2001, Volume: 16, Issue:4

    Topics: Adult; Arthritis, Rheumatoid; Aspirin; Autoimmune Diseases; Blood Platelets; Combined Modality Thera

2001

Trials

2 trials available for dipyridamole and Rheumatoid Arthritis

ArticleYear
Adenosine and cytokine levels following treatment of rheumatoid arthritis with dipyridamole.
    Rheumatology international, 2006, Volume: 27, Issue:1

    Topics: Adenosine; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cytokines; Dipyridamole; Dose-Response Re

2006
Purine metabolism and clinical status of patients with rheumatoid arthritis treated with dipyridamole.
    Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:9-11

    Topics: Adenosine; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chromatography,

2006

Other Studies

6 other studies available for dipyridamole and Rheumatoid Arthritis

ArticleYear
Innovative combination strategy to enhance effect and diminish adverse effects of glucocorticoids: another promise?
    Arthritis research & therapy, 2009, Volume: 11, Issue:1

    Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Dipyridamole; Drug Therapy, Combination; Gluco

2009
Non-invasive assessment of coronary flow reserve and ADMA levels: a case-control study of early rheumatoid arthritis patients.
    Rheumatology (Oxford, England), 2009, Volume: 48, Issue:7

    Topics: Adult; Aged; Arginine; Arthritis, Rheumatoid; Biomarkers; Carotid Artery, Common; Case-Control Studi

2009
Methotrexate modulates the kinetics of adenosine in humans in vivo.
    Annals of the rheumatic diseases, 2006, Volume: 65, Issue:4

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adult; Aged; Antirheumatic Agents; A

2006
[Detection of myocardial lesions by dipyridamole thallium-201 scintigraphy in patients with rheumatoid arthritis].
    Ryumachi. [Rheumatism], 1995, Volume: 35, Issue:3

    Topics: Aged; Arthritis, Rheumatoid; Cardiomyopathies; Dipyridamole; Female; Heart; Humans; Male; Middle Age

1995
Reduced red blood cell deformability in patients with rheumatoid vasculitis. Improvement after in vitro treatment with dipyridamole.
    Arthritis and rheumatism, 1995, Volume: 38, Issue:2

    Topics: Adult; Aged; Arthritis, Rheumatoid; Dipyridamole; Erythrocyte Deformability; Female; Filtration; Hum

1995
[The effect of various drugs in clinical use on thrombocyte functions].
    Folia haematologica (Leipzig, Germany : 1928), 1969, Volume: 92, Issue:4

    Topics: Adolescent; Adult; Aged; Aminobenzoates; Aminocaproates; Arthritis, Rheumatoid; Aspirin; Blood Coagu

1969