Page last updated: 2024-11-01

niclosamide and Rheumatoid Arthritis

niclosamide has been researched along with Rheumatoid Arthritis in 4 studies

Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.

Research Excerpts

ExcerptRelevanceReference
"This study designed to identify the therapeutic efficacy of niclosamide (NCL) in Iraqi patients suffering from active rheumatoid arthritis (RA) who were using etanercept (ETN) for more than 3 months and still had high or moderate active RA."9.27Niclosamide as an adjuvant to etanercept in treatment patients with active rheumatoid arthritis: an 8-week randomized controlled pilot study. ( Al-Gareeb, AIA; Gorial, FI; Mahmood, AS, 2018)
"To explore the effects of niclosamide on the viability and apoptosis of rheumatoid arthritis of fibroblast-like synoviocytes (rheumatoid arthritis (RA)fibroblast-like synoviocytes (FLS)), FLS obtained from RA patients were treated with niclosamide."7.83Niclosamide induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes. ( Huang, M; Liang, L; Qiu, Q; Shi, M; Xiao, Y; Xu, H; Yang, X; Zeng, S; Zou, Y, 2016)
"This study evaluated the anti-inflammatory effect of niclosamide in tumor necrosis factor (TNF)-α-stimulated human rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) and inhibitory effects on migration and invasion in RA FLS and investigated the signal mechanism, and further explored the treatment activity of niclosamide on collagen-induced arthritis (CIA)."7.81Inhibitory effects of niclosamide on inflammation and migration of fibroblast-like synoviocytes from patients with rheumatoid arthritis. ( Huang, M; Lao, M; Liang, L; Shi, M; Xiao, Y; Xu, H; Yang, X; Zen, S; Zou, Y, 2015)
"This study designed to identify the therapeutic efficacy of niclosamide (NCL) in Iraqi patients suffering from active rheumatoid arthritis (RA) who were using etanercept (ETN) for more than 3 months and still had high or moderate active RA."5.27Niclosamide as an adjuvant to etanercept in treatment patients with active rheumatoid arthritis: an 8-week randomized controlled pilot study. ( Al-Gareeb, AIA; Gorial, FI; Mahmood, AS, 2018)
"Niclosamide is an oral antihelminthic drug used to treat parasitic infections in millions of people worldwide."4.98Niclosamide: Beyond an antihelminthic drug. ( Chen, W; Mook, RA; Premont, RT; Wang, J, 2018)
"To explore the effects of niclosamide on the viability and apoptosis of rheumatoid arthritis of fibroblast-like synoviocytes (rheumatoid arthritis (RA)fibroblast-like synoviocytes (FLS)), FLS obtained from RA patients were treated with niclosamide."3.83Niclosamide induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes. ( Huang, M; Liang, L; Qiu, Q; Shi, M; Xiao, Y; Xu, H; Yang, X; Zeng, S; Zou, Y, 2016)
"This study evaluated the anti-inflammatory effect of niclosamide in tumor necrosis factor (TNF)-α-stimulated human rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) and inhibitory effects on migration and invasion in RA FLS and investigated the signal mechanism, and further explored the treatment activity of niclosamide on collagen-induced arthritis (CIA)."3.81Inhibitory effects of niclosamide on inflammation and migration of fibroblast-like synoviocytes from patients with rheumatoid arthritis. ( Huang, M; Lao, M; Liang, L; Shi, M; Xiao, Y; Xu, H; Yang, X; Zen, S; Zou, Y, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, W1
Mook, RA1
Premont, RT1
Wang, J1
Al-Gareeb, AIA1
Gorial, FI1
Mahmood, AS1
Liang, L2
Huang, M2
Xiao, Y2
Zen, S1
Lao, M1
Zou, Y2
Shi, M2
Yang, X2
Xu, H2
Zeng, S1
Qiu, Q1

Reviews

1 review available for niclosamide and Rheumatoid Arthritis

ArticleYear
Niclosamide: Beyond an antihelminthic drug.
    Cellular signalling, 2018, Volume: 41

    Topics: Animals; Anthelmintics; Arthritis, Rheumatoid; Diabetes Mellitus, Type 2; Disease Models, Animal; En

2018

Trials

1 trial available for niclosamide and Rheumatoid Arthritis

ArticleYear
Niclosamide as an adjuvant to etanercept in treatment patients with active rheumatoid arthritis: an 8-week randomized controlled pilot study.
    Clinical rheumatology, 2018, Volume: 37, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Sedimentation; Cy

2018

Other Studies

2 other studies available for niclosamide and Rheumatoid Arthritis

ArticleYear
Inhibitory effects of niclosamide on inflammation and migration of fibroblast-like synoviocytes from patients with rheumatoid arthritis.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2015, Volume: 64, Issue:3-4

    Topics: Animals; Anticestodal Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Movement; Cells,

2015
Niclosamide induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes.
    International immunopharmacology, 2016, Volume: 31

    Topics: Acetylcysteine; Apoptosis; Arthritis, Rheumatoid; bcl-2-Associated X Protein; Caspase 3; Caspase 9;

2016