acetaldehyde has been researched along with Rheumatoid Arthritis in 14 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Autoantibodies to malondialdehyde (MDA) proteins constitute a subset of anti-modified protein autoantibodies in rheumatoid arthritis (RA), which is distinct from citrulline reactivity." | 8.31 | Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients. ( Biese, C; Grönwall, C; Hansson, M; Hensvold, A; Israelsson, L; Joshua, V; Klareskog, L; Malmström, V; Sahlström, P; Scheel-Toellner, D; Stålesen, R; Valkovskaia, V; Végvári, Á, 2023) |
| "To examine serum autoantibodies to malondialdehyde-acetaldehyde (MAA) prior to rheumatoid arthritis (RA) diagnosis." | 7.96 | Autoantibodies to Malondialdehyde-Acetaldehyde Are Detected Prior to Rheumatoid Arthritis Diagnosis and After Other Disease Specific Autoantibodies. ( Deane, KD; Duryee, MJ; Edison, J; England, BR; Feser, ML; Hunter, CD; Kay Moss, L; Kelmenson, LB; Meeshaw, E; Mikuls, TR; Parish, MC; Sayles, H; Thiele, GM; Wagner, B, 2020) |
| "To compare serum anti-malondialdehyde-acetaldehyde (anti-MAA) antibody levels and MAA expression in lung tissue from patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD) to those found in controls." | 7.91 | Malondialdehyde-Acetaldehyde Adducts and Antibody Responses in Rheumatoid Arthritis-Associated Interstitial Lung Disease. ( Ascherman, DP; Caplan, L; Deane, KD; Demoruelle, MK; Duryee, MJ; England, BR; Klassen, LW; Mahajan, TD; Mikuls, TR; Poole, JA; Roul, P; Singh, N; Thiele, GM, 2019) |
| "To compare anti-malondialdehyde-acetaldehyde (MAA) antibody concentrations between rheumatoid arthritis (RA) patients and healthy and rheumatic disease controls." | 7.88 | Malondialdehyde-acetaldehyde antibody concentrations in rheumatoid arthritis and other rheumatic conditions. ( Anderson, DR; Duryee, MJ; England, BR; Hearth-Holmes, M; Hunter, C; Klassen, LW; McGowan, JD; Michaud, K; Mikuls, TR; Payne, JB; Sayles, H; Su, K; Thiele, GM, 2018) |
| "Autoantibodies to malondialdehyde (MDA) proteins constitute a subset of anti-modified protein autoantibodies in rheumatoid arthritis (RA), which is distinct from citrulline reactivity." | 4.31 | Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients. ( Biese, C; Grönwall, C; Hansson, M; Hensvold, A; Israelsson, L; Joshua, V; Klareskog, L; Malmström, V; Sahlström, P; Scheel-Toellner, D; Stålesen, R; Valkovskaia, V; Végvári, Á, 2023) |
| "Post-translational modifications of extracellular matrix proteins such as fibrinogen may lead to tolerance loss and have been implicated in rheumatoid arthritis (RA) pathogenesis." | 4.12 | Peptidyl arginine deiminase expression and macrophage polarization following stimulation with citrullinated and malondialdehyde-acetaldehyde modified fibrinogen. ( Aripova, N; Bierman, MM; Daubach, EC; Duryee, MJ; England, BR; Hunter, CD; Jones, SQ; Mikuls, TR; Mitra, A; Ragland, AS; Romberger, DJ; Ryan, EM; Thiele, GM, 2022) |
| "Malondialdehyde-acetaldehyde adducts (MAA) act as potent immune adjuvants and co-localize with citrullinated antigens in tissues effected by rheumatoid arthritis (RA)." | 3.96 | Immunogenic and inflammatory responses to citrullinated proteins are enhanced following modification with malondialdehyde-acetaldehyde adducts. ( Daubach, EC; Duryee, MJ; England, BR; Fletcher, BS; Hunter, CD; Klassen, LW; Mikuls, TR; Pospisil, TP; Thiele, GM, 2020) |
| "To examine serum autoantibodies to malondialdehyde-acetaldehyde (MAA) prior to rheumatoid arthritis (RA) diagnosis." | 3.96 | Autoantibodies to Malondialdehyde-Acetaldehyde Are Detected Prior to Rheumatoid Arthritis Diagnosis and After Other Disease Specific Autoantibodies. ( Deane, KD; Duryee, MJ; Edison, J; England, BR; Feser, ML; Hunter, CD; Kay Moss, L; Kelmenson, LB; Meeshaw, E; Mikuls, TR; Parish, MC; Sayles, H; Thiele, GM; Wagner, B, 2020) |
| "To compare serum anti-malondialdehyde-acetaldehyde (anti-MAA) antibody levels and MAA expression in lung tissue from patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD) to those found in controls." | 3.91 | Malondialdehyde-Acetaldehyde Adducts and Antibody Responses in Rheumatoid Arthritis-Associated Interstitial Lung Disease. ( Ascherman, DP; Caplan, L; Deane, KD; Demoruelle, MK; Duryee, MJ; England, BR; Klassen, LW; Mahajan, TD; Mikuls, TR; Poole, JA; Roul, P; Singh, N; Thiele, GM, 2019) |
| "To compare anti-malondialdehyde-acetaldehyde (MAA) antibody concentrations between rheumatoid arthritis (RA) patients and healthy and rheumatic disease controls." | 3.88 | Malondialdehyde-acetaldehyde antibody concentrations in rheumatoid arthritis and other rheumatic conditions. ( Anderson, DR; Duryee, MJ; England, BR; Hearth-Holmes, M; Hunter, C; Klassen, LW; McGowan, JD; Michaud, K; Mikuls, TR; Payne, JB; Sayles, H; Su, K; Thiele, GM, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 9 (64.29) | 2.80 |
| Authors | Studies |
|---|---|
| Lomzenski, HE | 1 |
| Thiele, GM | 9 |
| Duryee, MJ | 9 |
| Chen, SC | 1 |
| Ye, F | 1 |
| Anderson, DR | 4 |
| Mikuls, TR | 9 |
| Ormseth, MJ | 1 |
| Aripova, N | 1 |
| Hunter, CD | 5 |
| Ryan, EM | 1 |
| Daubach, EC | 2 |
| Jones, SQ | 1 |
| Bierman, MM | 1 |
| Ragland, AS | 1 |
| Mitra, A | 1 |
| England, BR | 6 |
| Romberger, DJ | 1 |
| Rodriguez-Martinez, L | 1 |
| García-Moreno, C | 1 |
| Perez-Pampin, E | 1 |
| Gómara, MJ | 1 |
| Sarmiento-Monroy, JC | 1 |
| Lopez-Golán, Y | 1 |
| Gómez-Puerta, JA | 1 |
| Mera-Varela, A | 1 |
| Conde, C | 1 |
| Sanmartí, R | 1 |
| Haro, I | 1 |
| González, A | 1 |
| Sahlström, P | 1 |
| Joshua, V | 1 |
| Valkovskaia, V | 1 |
| Biese, C | 1 |
| Stålesen, R | 1 |
| Israelsson, L | 1 |
| Végvári, Á | 1 |
| Scheel-Toellner, D | 1 |
| Klareskog, L | 1 |
| Hansson, M | 1 |
| Hensvold, A | 1 |
| Malmström, V | 1 |
| Grönwall, C | 1 |
| van den Beukel, MD | 1 |
| van Wesemael, TJ | 1 |
| Hoogslag, ATW | 1 |
| Borggreven, NV | 1 |
| Huizinga, TW | 1 |
| van der Helm-van Mil, AH | 1 |
| Toes, RE | 1 |
| van der Woude, D | 1 |
| Trouw, LA | 1 |
| Fletcher, BS | 1 |
| Pospisil, TP | 1 |
| Klassen, LW | 5 |
| Edison, J | 1 |
| Meeshaw, E | 1 |
| Sayles, H | 4 |
| Kelmenson, LB | 1 |
| Kay Moss, L | 1 |
| Feser, ML | 1 |
| Wagner, B | 1 |
| Parish, MC | 1 |
| Deane, KD | 2 |
| Petro, AD | 1 |
| Dougherty, J | 1 |
| Kremer, JM | 1 |
| Pappas, DA | 1 |
| Robinson, WH | 3 |
| Curtis, JR | 1 |
| Azizov, V | 1 |
| Zaiss, MM | 1 |
| Rahman, R | 1 |
| Sayles, HR | 1 |
| Hollins, A | 1 |
| Michaud, K | 2 |
| Wolfe, F | 1 |
| Thiele, GE | 1 |
| Sokolove, J | 2 |
| Lingampalli, N | 1 |
| Nicholas, AP | 2 |
| Talmon, GA | 1 |
| Su, K | 2 |
| Zimmerman, MC | 1 |
| Hearth-Holmes, M | 1 |
| Payne, JB | 1 |
| Hunter, C | 1 |
| McGowan, JD | 1 |
| Roul, P | 1 |
| Mahajan, TD | 1 |
| Singh, N | 1 |
| Poole, JA | 1 |
| Ascherman, DP | 1 |
| Caplan, L | 1 |
| Demoruelle, MK | 1 |
| Mohring, SM | 1 |
| Young, KA | 1 |
| Benissan-Messan, D | 1 |
| Dusad, A | 1 |
| O'Dell, JR | 1 |
| Tuma, DJ | 1 |
| Darrah, E | 1 |
| Andrade, F | 1 |
2 reviews available for acetaldehyde and Rheumatoid Arthritis
| Article | Year |
|---|---|
Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression.
Topics: Acetaldehyde; Arthritis, Rheumatoid; Autoantibodies; Humans; Immunoglobulin G; Malondialdehyde; Pept | 2023 |
Alcohol Consumption in Rheumatoid Arthritis: A Path through the Immune System.
Topics: Acetaldehyde; Acetates; Alcohol Drinking; Arthritis, Rheumatoid; Ethanol; Humans; Immune System; Pro | 2021 |
12 other studies available for acetaldehyde and Rheumatoid Arthritis
| Article | Year |
|---|---|
Serum anti-malondialdehyde-acetaldehyde IgA antibody concentration improves prediction of coronary atherosclerosis beyond traditional risk factors in patients with rheumatoid arthritis.
Topics: Acetaldehyde; Arthritis, Rheumatoid; Atherosclerosis; Autoantibodies; C-Reactive Protein; Coronary A | 2022 |
Peptidyl arginine deiminase expression and macrophage polarization following stimulation with citrullinated and malondialdehyde-acetaldehyde modified fibrinogen.
Topics: Acetaldehyde; Arthritis, Rheumatoid; Citrulline; Fibrinogen; Humans; Hydrolases; Macrophages; Malond | 2022 |
Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients.
Topics: Acetaldehyde; Arthritis, Rheumatoid; Autoantibodies; Autoimmunity; B-Lymphocytes; Bone Marrow; Human | 2023 |
Antibodies against advanced glycation end-products and malondialdehyde-acetaldehyde adducts identify a new specific subgroup of hitherto patients with seronegative arthritis with a distinct clinical phenotype and an HLA class II association.
Topics: Acetaldehyde; Arthritis, Rheumatoid; Autoantibodies; Humans; Inflammation; Maillard Reaction; Malond | 2023 |
Immunogenic and inflammatory responses to citrullinated proteins are enhanced following modification with malondialdehyde-acetaldehyde adducts.
Topics: Acetaldehyde; Adjuvants, Immunologic; Animals; Anti-Citrullinated Protein Antibodies; Arthritis, Rhe | 2020 |
Autoantibodies to Malondialdehyde-Acetaldehyde Are Detected Prior to Rheumatoid Arthritis Diagnosis and After Other Disease Specific Autoantibodies.
Topics: Acetaldehyde; Adult; Anti-Citrullinated Protein Antibodies; Arthritis, Rheumatoid; Autoantibodies; C | 2020 |
Associations between an expanded autoantibody profile and treatment responses to biologic therapies in patients with rheumatoid arthritis.
Topics: Acetaldehyde; Adult; Aged; Anti-Citrullinated Protein Antibodies; Antirheumatic Agents; Arthritis, R | 2021 |
Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint.
Topics: Acetaldehyde; Aged; Arthritis, Rheumatoid; Autoantibodies; Case-Control Studies; Female; Humans; Imm | 2017 |
Malondialdehyde-acetaldehyde antibody concentrations in rheumatoid arthritis and other rheumatic conditions.
Topics: Acetaldehyde; Adult; Aged; Arthritis, Rheumatoid; Autoantibodies; Case-Control Studies; Diagnosis, D | 2018 |
Malondialdehyde-Acetaldehyde Adducts and Antibody Responses in Rheumatoid Arthritis-Associated Interstitial Lung Disease.
Topics: Acetaldehyde; Aged; Antibody Formation; Arthritis, Rheumatoid; Autoantibodies; Autoantigens; Case-Co | 2019 |
Malondialdehyde-acetaldehyde adducts and anti-malondialdehyde-acetaldehyde antibodies in rheumatoid arthritis.
Topics: Acetaldehyde; Adult; Aged; Arthritis, Rheumatoid; Autoantibodies; Cross Reactions; Enzyme-Linked Imm | 2015 |
Editorial: citrullination, and carbamylation, and malondialdehyde-acetaldehyde! Oh my! Entering the forest of autoantigen modifications in rheumatoid arthritis.
Topics: Acetaldehyde; Arthritis, Rheumatoid; Autoantibodies; Female; Humans; Male; Malondialdehyde | 2015 |