flufenamic acid has been researched along with Rheumatoid Arthritis in 56 studies
Flufenamic Acid: An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
flufenamic acid : An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. An analgesic and anti-inflammatory, it is used in rheumatic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The absorption of etofenamate (CAS 30544-47-9, Rheumon gel) by iontophoresis in 11 patients with low back pain and in 13 patients with synovitis of the knee was evaluated." | 5.09 | Etofenamate levels in human serum and synovial fluid following iontophoresis. ( Bálint, G; Bariska, J; Bender, T; Rojkovich, B, 2001) |
| " Levels of PGB (presumed to arise from PGE) in synovial fluids are elevated in the majority of a group of patients with inflammatory rheumatic diseases, as compared to similar patients treated with aspirin and indomethacin and patients with osteoarthritis." | 3.65 | Prostaglandins in the rheumatic diseases. ( Levine, L; McGuire, MB; Robinson, DR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (98.21) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (1.79) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| COODLEY, EL | 1 |
| Simpson, MR | 2 |
| Simpson, NR | 2 |
| Masheter, HC | 4 |
| Hardy, SM | 1 |
| Sydnes, OA | 2 |
| Mason, RM | 1 |
| Barnardo, DE | 1 |
| Fox, WR | 1 |
| Weatherall, M | 2 |
| Tsvetkova, ES | 1 |
| Sigidin, IaA | 1 |
| Kagan, G | 1 |
| Huddlestone, L | 1 |
| Wolstencroft, P | 1 |
| Bender, T | 1 |
| Bariska, J | 1 |
| Rojkovich, B | 1 |
| Bálint, G | 1 |
| Heindl, I | 1 |
| Lorenz, D | 1 |
| Sieberns, S | 1 |
| Blumberger, W | 1 |
| Robinson, DR | 1 |
| McGuire, MB | 1 |
| Levine, L | 1 |
| Leynadier, F | 1 |
| Perrault, M | 1 |
| Mavrikakis, ME | 1 |
| Madkour, MM | 1 |
| Buchanan, WW | 2 |
| Reinicke, C | 1 |
| Shichikawa, K | 1 |
| Onoda, T | 1 |
| Klein, G | 1 |
| Wottawa, A | 1 |
| Wax, J | 1 |
| Tessman, DK | 1 |
| Winder, CV | 1 |
| Stephens, MD | 1 |
| Cherevatov, BG | 1 |
| Shelest, AN | 1 |
| Volnenko, NB | 1 |
| Cherevatova, SKh | 1 |
| Kluft, C | 1 |
| Cooper, P | 1 |
| Jie, AF | 1 |
| Lowe, GD | 1 |
| Forbes, CD | 1 |
| Blamey, SL | 1 |
| van de Putte, LB | 1 |
| Mastandrea, G | 1 |
| Migliari, M | 1 |
| De Salcedo, I | 1 |
| Fonseca Ferreira, FM | 1 |
| Silva, JL | 1 |
| Carrington, MD | 1 |
| Mizushima, Y | 1 |
| Cosh, JA | 1 |
| Siegmeth, W | 1 |
| Herkner, W | 1 |
| Tausch, G | 1 |
| Tuschl, P | 1 |
| Dunky, A | 1 |
| Eberl, R | 1 |
| Fujimura, H | 1 |
| Tsurumi, K | 1 |
| Go, K | 1 |
| Hiramatsu, Y | 1 |
| Tamura, Y | 1 |
| Evans, DP | 1 |
| Lees, LJ | 1 |
| Wawrzyńska-Pagowska, J | 1 |
| Mathies, H | 3 |
| Kanková, D | 1 |
| Vojtísek, O | 1 |
| Pavelka, K | 1 |
| Hándlová, D | 1 |
| Jeremy, R | 1 |
| Eichhorn, M | 1 |
| Bain, LS | 1 |
| Fearnley, ME | 2 |
| Hill, AG | 2 |
| Cardoe, N | 1 |
| Beltrán Gutiérrez, J | 1 |
| Fernández del Vallado, P | 1 |
| Gijón Baños, J | 1 |
| Dick, WC | 1 |
| Schmied, P | 1 |
| Van Rossum, P | 1 |
| Fallet, GH | 1 |
| Bossa, G | 1 |
| Giordano, M | 1 |
| Camus, JP | 1 |
| Tudhope, GR | 1 |
| Cabanel, G | 1 |
| Phélip, X | 1 |
| Verdier, JM | 1 |
| Rajan, KT | 1 |
| Barr, A | 1 |
| Whitwell, E | 1 |
| Böni, A | 1 |
| López Prats, JL | 1 |
| Hingorani, K | 1 |
| Kater, RM | 1 |
| Brown, JH | 1 |
| Mackey, HK | 1 |
| Gigante, D | 1 |
| Teodori, S | 1 |
| Homma, M | 1 |
6 reviews available for flufenamic acid and Rheumatoid Arthritis
| Article | Year |
|---|---|
[Nonsteroid antirheumatic agents].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fenoprofen; Flufenamic Acid; Humans; Indomethacin; | 1977 |
[Clinical use of non-steroid anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arthritis, Rheumatoid; Aspirin; Cell Mi | 1974 |
A critical appraisal of therapy in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Antimetabolites; Arthritis, Rheumatoid; Aspirin; Flufenamic | 1968 |
Review of flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diarrhea; Dyspep | 1966 |
Advances in the treatment of rheumatic disorders.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chloroquine; Female; Flu | 1971 |
[The conservative treatment of chronic inflammatory rheumatism].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Analgesics; Anti-Inflammatory Agents; Antimalarials; Art | 1969 |
19 trials available for flufenamic acid and Rheumatoid Arthritis
| Article | Year |
|---|---|
Controlled clinical trial of flufenamic acid in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Flufenamic Acid; Humans; Indomethaci | 1967 |
[Comparative effectiveness of new antirheumatic drugs].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Flufenamic Ac | 1980 |
Flufenamic acid and placebo compared in rheumatoid arthritis and osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Fl | 1981 |
Etofenamate levels in human serum and synovial fluid following iontophoresis.
Topics: Administration, Topical; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chromatography, High Press | 2001 |
[Clinical trial of the new percutaneously active antirheumatic etofenamate. Summarising report (author's transl)].
Topics: Administration, Topical; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Back Pain; Bursitis; Clinic | 1977 |
[Effect of niflumic acid on chronic rheumatoid arthritis].
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation; Female; Flufena | 1976 |
[Experiences with a new combination drug (Realin) in the treatment of acute rheumatic conditions].
Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Combinations; Drug | 1974 |
Trial design for assessing initiation of anti-inflammatory therapy.
Topics: Adult; Analgesics; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Dose-Respon | 1972 |
[Evaluation of the therapeutic action of flufenamic acid in patients with chronic polyarthritis in a double blind study].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Flufenamic Acid; Humans; | 1967 |
Flufenamic acid and indomethacin in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diarrhea; Digestion; Fema | 1966 |
An investigation of possible synergism between flufenamic acid and prednisone.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Synergism; Flufenami | 1966 |
Clinical trials of the fenamates. The value of computers in analysing clinical trials.
Topics: Analysis of Variance; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Com | 1966 |
Review of flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diarrhea; Dyspep | 1966 |
A controlled clinical trial of flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Flufenamic Acid; | 1966 |
A clinical trial of flufenamic acid in the treatment of rheumatoid arthritis.
Topics: Abdomen, Acute; Acetaminophen; Aluminum; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspartate | 1966 |
[Double-blind study using flufenamic acid (F.I. 440) and oxyphenylbutazone in rheumatoid arthritis and ankylosing spine].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Flufenamic Acid; Fluorine | 1968 |
Flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Clinical Trials as To | 1967 |
Double-blind crossover trial comparing ibuprofen with flufenamic acid in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Benzyl Compounds; Female; Flufenamic A | 1970 |
Double-blind evaluation of the analgesic and toxic effects of flufenamic acid and mefenamic acid in patients with chronic pain.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Humans; Mefenamic Acid; | 1968 |
32 other studies available for flufenamic acid and Rheumatoid Arthritis
| Article | Year |
|---|---|
Evaluation of drug therapy in rheumatoid arthritis-study of flufenamic acid.
Topics: Arthritis; Arthritis, Rheumatoid; Flufenamic Acid; Humans; ortho-Aminobenzoates | 1963 |
Flufenamic acid in rheumatoid arthritis. The second six months of treatment.
Topics: Alanine Transaminase; Alcohol Oxidoreductases; Alkaline Phosphatase; Anti-Inflammatory Agents; Arthr | 1966 |
Assessment of drugs in out-patients with rheumatoid arthritis. Evaluation of methods and a comparison of mefenamic and flufenamic acids with phenylbutazone and aspirin.
Topics: Acetaminophen; Adult; Agglutination Tests; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; | 1967 |
Flufenamic acid in rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Guinea Pigs; Hu | 1967 |
Prostaglandins in the rheumatic diseases.
Topics: Arthritis, Rheumatoid; Aspirin; Bone Resorption; Cell Line; Colchicine; Cyclic AMP; Flufenamic Acid; | 1975 |
[Anti-inflammatory agents in current therapeutics].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi | 1975 |
The place of mefenamic acid in the treatment of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Flufenamic Acid; Humans; Mefenamic A | 1978 |
[Effect of antirheumatic agents on DNA-systems and DNA repair of various cell systems].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; DNA; DNA Repair; Flufenamic Acid; Humans; In Vitro | 1976 |
A sensitive method for the comparative bioassay of nonsteroidal anti-inflammatory compounds in adjuvant-induced primary inflammation in the rat.
Topics: Aminopyrine; Analysis of Variance; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin | 1975 |
[Topical use of Rheumon-Gel in the combined treatment of patients with rheumatoid arthritis].
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Diclofenac; Drug Ev | 1987 |
Evaluation of euglobulin methods for the study of blood fibrinolytic activity: results for patients with rheumatoid arthritis and in the postoperative period.
Topics: Abdomen; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Chemical Fractionation; Complement C1 Inact | 1985 |
[Clinical studies on the use of a new combination of substances with antirheumatic action in the treatment of osteo-articular painful syndromes].
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Back Pain; Cervical Vertebrae; Drug Combinations; Dru | 1974 |
Some metabolic and hormonal effects of flufenamic acid.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Albuminuria; Alcohols; Anti-Inflammatory Agents; Arthr | 1966 |
Method of treatment of rheumatoid arthritis in different countries.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chloroquine; | 1966 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin | 1974 |
[In vivo investigation of the effect of antirheumatic drugs on DNA synthesis and DNA repair in patients with chronic rheumatoid arthritis (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Chronic Disease; Dimethylamines; DNA; DNA Repair; Female; Flufen | 1974 |
[Pharmacological study of phthalazino-(2,3-b)-phthalazine-5 (14H), 12(7H)-dione (L-5418)].
Topics: Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Barbiturates; Blood Co | 1974 |
[Therapy of chronic polyarthritis. 2].
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Betamethasone; Dexamethasone; Flufenamic Ac | 1972 |
[Our experience with the new antirheumatic drug niflumic acid].
Topics: Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Drug The | 1974 |
[Use of indomethacin in combination with other antirheumatic drugs in the therapy of chronic inflammatory rheumatism].
Topics: Arthritis, Rheumatoid; Aspirin; Chronic Disease; Dexamethasone; Drug Synergism; Flufenamic Acid; Gol | 1972 |
[The new anti-inflammatory acids. Niflumic acid in rheumatology].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Humans; Mefenamic Acid; | 1968 |
[Possibilities and limitations of an antirheumatic therapy].
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Balneology; Drug Synergism; Electric Stimulation The | 1968 |
Discussion on clinical trials of the fenamates.
Topics: Analgesia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Central Nervous System; Flufena | 1966 |
Comparison of flufenamic acid with aspirin and paracetamol in terms of gastrointestinal blood loss.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chromium Isotopes; Fe | 1966 |
[Flufenamic acid in rheumatology].
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Female; Flufenamic Acid; Gastritis; Gastrointestinal | 1970 |
[Therapy of progressive chronic polyarthritis].
Topics: Arthritis, Rheumatoid; Chronic Disease; Cortisone; Flufenamic Acid; Gold; Humans; Indoles; Mefenamic | 1970 |
[Clinical experience with the flufenamic acid--thyocolchicoside combination].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Colchicine; Flufenamic Acid; Fluorine; Glycosides; | 1970 |
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufen | 1968 |
[Flufenamic acid in the therapy of rheumatoid arthritis].
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Flufenamic Acid; Fluorine; Hum | 1968 |
[Clinical evaluation of non-steroid anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Flufenamic Acid; Humans; Indomethacin; Inf | 1968 |
New drugs. VII. A controlled trial of flufenamic acid therapy in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Female; Flufenamic Acid; Human | 1966 |
New drugs. 8. Flufenamic acid in rheumatoid arthritis. Comparison with aspirin and the results of extended treatment.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Diarrhea; Flufenamic | 1966 |