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sulforaphane and Rheumatoid Arthritis

sulforaphane has been researched along with Rheumatoid Arthritis in 5 studies

sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.

Research Excerpts

ExcerptRelevanceReference
"This study was performed to define the effects of sulforaphane on interleukin-1β (IL-1β)-induced proliferation of rheumatoid arthritis synovial fibroblasts (RASFs), the expression of matrix metalloproteinases (MMPs) and cyclooxygenase (COX), and the production of prostaglandin E2 (PGE2) by RASFs."7.80Sulforaphane inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of MMPs, COX-2, and PGE2. ( Choi, YJ; Lee, EG; Lee, WS; Sung, MS; Yoo, WH, 2014)
"To investigate whether sulforaphane (SFN), an isothiocyanate derived from cruciferous vegetables such as broccoli, regulates synoviocyte hyperplasia and T cell activation in rheumatoid arthritis (RA)."7.76Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate. ( Cho, CS; Chung, YJ; Kim, HA; Kim, HS; Kim, WU; Kong, JS; Ryu, SH; Yea, K; Yoo, SA, 2010)
"Sulforaphane (SFN) is a natural compound that has been suggested as an antioxidant."5.48Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund's Adjuvant-Induced Mono-Arthritis. ( Abreu-Silva, AL; da Penha, TA; de Aquino, AF; de Sá, JC; de Souza, BGGF; Fialho Sousa, NC; França Muniz, T; Grisotto, MAG; Nascimento da Silva, LC; Neuza da Silva Nina, L; Silva E Silva, C; Silva Rodrigues, JF; Soares Fernandes, E, 2018)
"This study was performed to define the effects of sulforaphane on interleukin-1β (IL-1β)-induced proliferation of rheumatoid arthritis synovial fibroblasts (RASFs), the expression of matrix metalloproteinases (MMPs) and cyclooxygenase (COX), and the production of prostaglandin E2 (PGE2) by RASFs."3.80Sulforaphane inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of MMPs, COX-2, and PGE2. ( Choi, YJ; Lee, EG; Lee, WS; Sung, MS; Yoo, WH, 2014)
"To investigate whether sulforaphane (SFN), an isothiocyanate derived from cruciferous vegetables such as broccoli, regulates synoviocyte hyperplasia and T cell activation in rheumatoid arthritis (RA)."3.76Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate. ( Cho, CS; Chung, YJ; Kim, HA; Kim, HS; Kim, WU; Kong, JS; Ryu, SH; Yea, K; Yoo, SA, 2010)
"Sulforaphane treatment reduced the arthritis score and the severity of histologic inflammation in CIA mice."1.62The anti-arthritis effect of sulforaphane, an activator of Nrf2, is associated with inhibition of both B cell differentiation and the production of inflammatory cytokines. ( Cho, ML; Jhun, J; Jung, K; Kim, SY; Kwon, JY; Min, JK; Moon, SJ; Ryu, J, 2021)
"Sulforaphane (SFN) is a natural compound that has been suggested as an antioxidant."1.48Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund's Adjuvant-Induced Mono-Arthritis. ( Abreu-Silva, AL; da Penha, TA; de Aquino, AF; de Sá, JC; de Souza, BGGF; Fialho Sousa, NC; França Muniz, T; Grisotto, MAG; Nascimento da Silva, LC; Neuza da Silva Nina, L; Silva E Silva, C; Silva Rodrigues, JF; Soares Fernandes, E, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Jiang, Y1
Li, HY1
Li, XH1
Lu, J1
Zhang, Q1
Bai, CG1
Chen, Y1
Moon, SJ1
Jhun, J1
Ryu, J1
Kwon, JY1
Kim, SY1
Jung, K1
Cho, ML1
Min, JK1
Silva Rodrigues, JF1
Silva E Silva, C1
França Muniz, T1
de Aquino, AF1
Neuza da Silva Nina, L1
Fialho Sousa, NC1
Nascimento da Silva, LC1
de Souza, BGGF1
da Penha, TA1
Abreu-Silva, AL1
de Sá, JC1
Soares Fernandes, E1
Grisotto, MAG1
Choi, YJ1
Lee, WS1
Lee, EG1
Sung, MS1
Yoo, WH1
Kong, JS1
Yoo, SA1
Kim, HS1
Kim, HA1
Yea, K1
Ryu, SH1
Chung, YJ1
Cho, CS1
Kim, WU1

Other Studies

5 other studies available for sulforaphane and Rheumatoid Arthritis

ArticleYear
Therapeutic effects of isothiocyanate prodrugs on rheumatoid arthritis.
    Bioorganic & medicinal chemistry letters, 2018, 02-15, Volume: 28, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Body Weight; Half-Life; Iso

2018
The anti-arthritis effect of sulforaphane, an activator of Nrf2, is associated with inhibition of both B cell differentiation and the production of inflammatory cytokines.
    PloS one, 2021, Volume: 16, Issue:2

    Topics: Animals; Arthritis, Rheumatoid; B-Lymphocytes; Cell Differentiation; Cytokines; Inflammation; Isothi

2021
Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund's Adjuvant-Induced Mono-Arthritis.
    Molecules (Basel, Switzerland), 2018, 04-24, Volume: 23, Issue:5

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Biomarkers; Cytokines; Disease Models, Anim

2018
Sulforaphane inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of MMPs, COX-2, and PGE2.
    Inflammation, 2014, Volume: 37, Issue:5

    Topics: Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Fibrobla

2014
Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:1

    Topics: Animals; Antirheumatic Agents; Apoptosis; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Survi

2010