Page last updated: 2024-10-30

lansoprazole and Rheumatoid Arthritis

lansoprazole has been researched along with Rheumatoid Arthritis in 3 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Research Excerpts

ExcerptRelevanceReference
" In this open-label study, the effect of lansoprazole 30 mg qd and naproxen 500 mg bid on the pharmacokinetic profile of methotrexate was investigated."6.71Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. ( Amer, F; Andhivarothai, N; Kukulka, MJ; Vakily, M, 2005)
" In this open-label study, the effect of lansoprazole 30 mg qd and naproxen 500 mg bid on the pharmacokinetic profile of methotrexate was investigated."2.71Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. ( Amer, F; Andhivarothai, N; Kukulka, MJ; Vakily, M, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyake, K1
Ueki, N1
Suzuki, K1
Shinji, Y1
Kusunoki, M1
Hiratsuka, T1
Nishigaki, H1
Tatsuguchi, A1
Futagami, S1
Wada, K1
Tsukui, T1
Nakajima, A1
Yoshino, S1
Sakamoto, C1
Vakily, M1
Amer, F1
Kukulka, MJ1
Andhivarothai, N1
Marshall, RW1
Marshall, VJ1
Hull, R1

Trials

2 trials available for lansoprazole and Rheumatoid Arthritis

ArticleYear
Preventive therapy for non-steroidal anti-inflammatory drug-induced ulcers in Japanese patients with rheumatoid arthritis: the current situation and a prospective controlled-study of the preventive effects of lansoprazole or famotidine.
    Alimentary pharmacology & therapeutics, 2005, Volume: 21 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer A

2005
Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents

2005

Other Studies

1 other study available for lansoprazole and Rheumatoid Arthritis

ArticleYear
Disease-modifying anti-rheumatic drugs are only one of a number of potential causes of myelosuppression: a careful drug history is necessary to elucidate the cause of an adverse event.
    Rheumatology (Oxford, England), 2006, Volume: 45, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Infective Agents; Antirheumatic Agents; Arthriti

2006