A lanosterol synthase that is encoded in the genome of Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446. [OMA:P33247, PRO:DNx]
EC 4.2.1.129;
EC 5.4.99.17;
Squalene--hopanol cyclase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| ro 48-8071 | Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 | IC50 | 0.0600 | 1 | 1 |
| umbelliprenin | Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 | IC50 | 70.0000 | 1 | 1 |
| farnesiferol c | Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 | IC50 | 7.0000 | 1 | 1 |
| ferulenol | Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 | IC50 | 90.0000 | 1 | 1 |