Page last updated: 2024-08-24

tenidap and Rheumatoid Arthritis

tenidap has been researched along with Rheumatoid Arthritis in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's22 (95.65)18.2507
2000's1 (4.35)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Breedveld, F1
Appelboom, T; Bolten, W; Breedveld, FC; Feely, J; Le Loët, X; Leeming, MR; Manthorpe, R; Marcolongo, R; Smolen, J; Wylie, G1
Caldwell, JR; Gardner, MJ; Hansen, RA; Kirby, DS1
Blackburn, WD; Caldwell, JR; Collins, RL; Fleischmann, R; Kaplan, H; Miller, MJ; Poiley, JE; Prupas, HM; Sikes, DH; Silverfield, JC1
Madhok, R1
Farrow, P; Kirby, DS; Kraska, AR; Leeming, MR; Loose, LD; Shanahan, WR; Sipe, JD; Stack, CB; Ting, N; Weiner, ES1
Drury, CE; Law, CG; Littman, BH; Stack, CB; Zimmerer, RO1
Alldersea, JE; Cotton, W; Fryer, AA; Jones, P; Mattey, DL; Nixon, N; Strange, RC; Zhao, L1
Breedveld, FC; de Kuiper, P; Dijkmans, BA; Dolhain, RJ; Miltenburg, AM; Penders, JM; Verweij, CL1
Emery, P; Richardson, CE1
Pruzanski, W; Vadas, P1
Swaak, AJ1
Canvin, JM; Madhok, R1
Jolicoeur, FC; Martel-Pelletier, J; Mineau, F; Ounissi-Benkalha, H; Pelletier, JP; Ranger, P; Tardif, G1
Fernandes, JC; Loose, L; Martel-Pelletier, J; Mineau, F; Pelletier, JP; Ranger, P; Tardif, G1
April, PA; Ballou, SP; Collins, RL; Daniels, JC; Dietz, AJ; Germain, BF; Gordon, G; Gum, OB; Hepburn, B; Katz, P; Loose, LD; Mehrban, M; Pariser, K; Prupas, HM; Spindler, JS; Ting, N; Turner, RA; Weisman, MH; Willkens, RF; Wolf, RE; Wolfe, F; Zizic, TM1
Hall, VC; Wolf, RE1
Anderson, NL; Buss, JM; Doherty, NS; Littman, BH; Reilly, K; Swindell, AC1
Aarons, L; Coates, P; Evans, L1
Andre, B; De Groote, D; Jaspar, JM; Kaiser, MJ; Kaye, O; Malaise, MG; Ribbens, C1
Blackburn, WD; Carty, TJ; Eskra, JD; Heck, LW; Loose, LD1
Bliven, ML; Downs, JT; Hanson, DC; Natoli, EJ; Otterness, IG1
Johnson, JA; Loeser, R; Smith, DM; Turner, RA1

Reviews

4 review(s) available for tenidap and Rheumatoid Arthritis

ArticleYear
Tenidap: a novel cytokine-modulating antirheumatic drug for the treatment of rheumatoid arthritis.
    Scandinavian journal of rheumatology. Supplement, 1994, Volume: 100

    Topics: Acute-Phase Proteins; Adult; Aged; Aged, 80 and over; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials, Phase III as Topic; Consumer Product Safety; Cytokines; Disease Models, Animal; Female; Humans; Indoles; Male; Middle Aged; Oxindoles; Rats; Treatment Outcome

1994
Tenidap.
    Lancet (London, England), 1995, Aug-19, Volume: 346, Issue:8973

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Humans; Indoles; Oxindoles

1995
Innovative treatment approaches for rheumatoid arthritis. New cyclo-oxygenase and cytokine inhibitors.
    Bailliere's clinical rheumatology, 1995, Volume: 9, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Cyclooxygenase Inhibitors; Cytokines; Digestive System; Drug Therapy, Combination; Humans; Indoles; Isoenzymes; Meloxicam; Misoprostol; Nabumetone; Oxindoles; Thiazines; Thiazoles

1995
Tenidap: not just another NSAID?
    Annals of the rheumatic diseases, 1996, Volume: 55, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; C-Reactive Protein; Humans; Indoles; Long-Term Care; Oxindoles; Proteinuria; Treatment Outcome

1996

Trials

8 trial(s) available for tenidap and Rheumatoid Arthritis

ArticleYear
A comparative study of tenidap, a cytokine-modulating anti-rheumatic drug, and diclofenac in rheumatoid arthritis: a 24-week analysis of a 1-year clinical trial.
    British journal of rheumatology, 1995, Volume: 34, Issue:6

    Topics: Acute-Phase Proteins; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Cytokines; Diclofenac; Female; Humans; Indoles; Male; Middle Aged; Oxindoles; Serum Amyloid A Protein; Treatment Outcome

1995
Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone.
    Arthritis and rheumatism, 1995, Volume: 38, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Indoles; Interleukin-6; Male; Middle Aged; Oxindoles; Piroxicam; Proteinuria; Time Factors; Treatment Outcome

1995
Reduction of acute-phase proteins with tenidap sodium, a cytokine-modulating anti-rheumatic drug.
    British journal of rheumatology, 1993, Volume: 32 Suppl 3

    Topics: Acute-Phase Proteins; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; C-Reactive Protein; Cytokines; Dose-Response Relationship, Drug; Female; Humans; Indoles; Male; Middle Aged; Naproxen; Oxindoles; Serum Amyloid A Protein

1993
Rheumatoid arthritis treated with tenidap and piroxicam. Clinical associations with cytokine modulation by tenidap.
    Arthritis and rheumatism, 1995, Volume: 38, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Cross-Over Studies; Cytokines; Double-Blind Method; Female; Humans; Indoles; Interleukin-1; Interleukin-6; Male; Middle Aged; Oxindoles; Pain Measurement; Piroxicam; Proteinuria; Serum Amyloid A Protein; Tumor Necrosis Factor-alpha

1995
Tenidap in patients with rheumatoid arthritis. A 4-week, placebo-controlled study.
    Scandinavian journal of rheumatology, 1996, Volume: 25, Issue:6

    Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Digestive System; Double-Blind Method; Female; Humans; Indoles; Male; Middle Aged; Oxindoles; Treatment Outcome

1996
A pharmacokinetic model for tenidap in normal volunteers and rheumatoid arthritis patients.
    Pharmaceutical research, 1999, Volume: 16, Issue:10

    Topics: Adult; Aged; Aging; Algorithms; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Humans; Indoles; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Oxindoles; Regression Analysis; Serum Albumin; Sex Characteristics

1999
Matrix metalloproteinase-3 serum levels are correlated with disease activity and predict clinical response in rheumatoid arthritis.
    The Journal of rheumatology, 2000, Volume: 27, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Female; Humans; Indoles; Interleukin-6; Linear Models; Male; Matrix Metalloproteinase 3; Methotrexate; Middle Aged; Oxindoles; Predictive Value of Tests; Severity of Illness Index; Treatment Outcome

2000
Evaluation of Tenidap (CP-66,248) on human neutrophil arachidonic acid metabolism, chemotactic potential and clinical efficacy in the treatment of rheumatoid arthritis.
    Agents and actions, 1990, Volume: 31, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Cell Migration Inhibition; Chemotaxis, Leukocyte; Chromatography, Thin Layer; Double-Blind Method; Humans; In Vitro Techniques; Indoles; Neutrophils; Oxindoles

1990

Other Studies

11 other study(ies) available for tenidap and Rheumatoid Arthritis

ArticleYear
The effects of age and gender on the pharmacokinetics of tenidap sodium in patients with rheumatoid arthritis and osteoarthritis.
    British journal of clinical pharmacology, 1995, Volume: 39 Suppl 1

    Topics: Adult; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Humans; Indoles; Male; Middle Aged; Osteoarthritis; Oxindoles; Sex Characteristics

1995
Alpha, mu and pi class glutathione S-transferases in human synovium and cultured synovial fibroblasts: effects of interleukin-1 alpha, hydrogen peroxide and inhibition of eicosanoid synthesis.
    Free radical research communications, 1993, Volume: 19, Issue:3

    Topics: Arthritis, Rheumatoid; Cells, Cultured; Eicosanoids; Fibroblasts; Glutathione Transferase; Humans; Hydrogen Peroxide; Immunoblotting; Immunohistochemistry; Indoles; Interleukin-1; Isoenzymes; Microscopy, Fluorescence; Oxindoles; Polymerase Chain Reaction; Superoxide Dismutase; Synovial Membrane

1993
Tenidap, but not nonsteroidal anti-inflammatory drugs, inhibits T-cell proliferation and cytokine induction.
    Scandinavian journal of immunology, 1995, Volume: 42, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Base Sequence; CD3 Complex; Cell Division; Clone Cells; Cytokines; DNA Primers; Humans; Indoles; Interleukin-2; Lymphocyte Activation; Molecular Sequence Data; Oxindoles; RNA, Messenger; Th1 Cells

1995
Tenidap in rheumatoid arthritis: comment on the article by Blackburn et al.
    Arthritis and rheumatism, 1996, Volume: 39, Issue:7

    Topics: Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Humans; Indoles; Oxindoles

1996
Tenidap versus diclofenac in rheumatoid arthritis.
    British journal of rheumatology, 1996, Volume: 35, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Humans; Indoles; Oxindoles

1996
In vitro effects of 2 antirheumatic drugs on the synthesis and expression of proinflammatory cytokines in synovial membranes from patients with rheumatoid arthritis.
    The Journal of rheumatology, 1996, Volume: 23, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Blotting, Northern; Cytokines; Humans; In Vitro Techniques; Indoles; Inflammation Mediators; Interleukin-1; Interleukin-6; Lipopolysaccharides; Naproxen; Oxindoles; Synovial Membrane; Tumor Necrosis Factor-alpha

1996
Tenidap reduces the level of interleukin 1 receptors and collagenase expression in human arthritic synovial fibroblasts.
    The Journal of rheumatology, 1996, Volume: 23, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blotting, Northern; Cells, Cultured; Collagenases; Diclofenac; Fibroblasts; Flow Cytometry; Humans; Hydroxychloroquine; Indoles; Osteoarthritis; Oxindoles; Polymerase Chain Reaction; Receptors, Interleukin-1; Synovial Membrane; Time Factors

1996
Effects of tenidap and nonsteroidal antiinflammatory drugs on the response of cultured human T cells to interleukin 2 in rheumatoid arthritis.
    The Journal of rheumatology, 1997, Volume: 24, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Binding Sites; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Humans; Indoles; Interleukin-2; Lymphocyte Activation; Oxindoles; T-Lymphocytes

1997
Analysis of changes in acute-phase plasma proteins in an acute inflammatory response and in rheumatoid arthritis using two-dimensional gel electrophoresis.
    Electrophoresis, 1998, Volume: 19, Issue:2

    Topics: Acute-Phase Proteins; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Proteins; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Indoles; Inflammation; Male; Oxindoles; Piroxicam; Sex Factors; Typhoid-Paratyphoid Vaccines

1998
Inhibition of 5-lipoxygenase product formation and polymorphonuclear cell degranulation by tenidap sodium in patients with rheumatoid arthritis.
    Arthritis and rheumatism, 1991, Volume: 34, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cell Degranulation; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Indoles; Lactoferrin; Leukotriene B4; Lipoxygenase Inhibitors; Middle Aged; Neutrophils; Oxindoles; Pancreatic Elastase; Radioimmunoassay; Synovial Fluid

1991
Inhibition of interleukin 1 synthesis by tenidap: a new drug for arthritis.
    Cytokine, 1991, Volume: 3, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cell Survival; Cytosol; Dinoprostone; In Vitro Techniques; Indoles; Interleukin-1; Lipopolysaccharides; Macrophages; Mice; Oxindoles; Protein Biosynthesis; SRS-A; Zymosan

1991