Compounds > 4-(3',4'-dimethoxyphenyl)but-3-en-1-ol
Page last updated: 2024-12-11

4-(3',4'-dimethoxyphenyl)but-3-en-1-ol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4-(3',4'-dimethoxyphenyl)but-3-en-1-ol: uterine relaxant isolated from Zingiber cassumunar Roxb. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
Zingibergenus[no description available]ZingiberaceaeA plant family of the order Zingiberales, subclass Zingiberidae, class Liliopsida. It includes plants which have both flavoring and medicinal properties such as GINGER; turmeric (CURCUMA), and cardamom (ELETTARIA).[MeSH]
Zingiber cassumunarspecies[no description available]ZingiberaceaeA plant family of the order Zingiberales, subclass Zingiberidae, class Liliopsida. It includes plants which have both flavoring and medicinal properties such as GINGER; turmeric (CURCUMA), and cardamom (ELETTARIA).[MeSH]

Cross-References

ID SourceID
PubMed CID6439118
SCHEMBL ID4092723
SCHEMBL ID2684387
MeSH IDM0152212

Synonyms (13)

Synonym
4-(3,4-dimethoxyphenyl)-3-buten-1-ol
dmp-butenol
(e)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol
4-(3',4'-dimethoxyphenyl)but-3-en-1-ol
69768-97-4
3-buten-1-ol, 4-(3,4-dimethoxyphenyl)-, (e)-
AKOS022184721
SCHEMBL4092723
SCHEMBL2684387
3-buten-1-ol, 4-(3,4-dimethoxyphenyl)-, (3e)-
(e)-4-(3,4-dimethoxyphenyl)-but-3-en-1-ol
methyl2-cyano-5-methoxybenzoate
FS-8969

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" In this study, we examined the pharmacokinetic profiles of Compound D in male Wistar rats."( Pharmacokinetics of Compound D, the Major Bioactive Component of Zingiber cassumunar, in Rats.
Anukunwithaya, T; Bangphumi, K; Dechatiwongse Na Ayudhya, T; Hunsakunachai, N; Inthachart, T; Jiratchariyakul, W; Khemawoot, P; Koontongkaew, S; Ongpipattanakul, B; Poachanukoon, O; Soawakontha, R, 2016)		0.43

Dosage Studied

ExcerptRelevanceReference
" Blood, tissues, urine, and feces were collected from 0 to 48 h after dosing and the level of Compound D was determined by liquid chromatography-tandem mass spectrometry."( Pharmacokinetics of Compound D, the Major Bioactive Component of Zingiber cassumunar, in Rats.
Anukunwithaya, T; Bangphumi, K; Dechatiwongse Na Ayudhya, T; Hunsakunachai, N; Inthachart, T; Jiratchariyakul, W; Khemawoot, P; Koontongkaew, S; Ongpipattanakul, B; Poachanukoon, O; Soawakontha, R, 2016)		0.43
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.53

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.53 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.53)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
1-butanol
1-Butanol: A four carbon linear hydrocarbon that has a hydroxy group at position 1.. butan-1-ol : A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes.		3.1550alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol		human metabolite;
mouse metabolite;
protic solvent
methanol
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.		2.1110alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Joint Pain
[description not available]		02.0710
Rheumatoid Arthritis
[description not available]		02.0710
Chondromalacia
Softening and degeneration of the CARTILAGE.		02.0710
Innate Inflammatory Response
[description not available]		02.0710
Arthritis, Rheumatoid
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.		02.0710
Cartilage Diseases
Pathological processes involving the chondral tissue (CARTILAGE).		02.0710
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.		02.0710
Arthralgia
Pain in the joint.		02.0710
Anasarca
[description not available]		02.1310
Edema
Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.		02.1310
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.		01.9710
Muscle Relaxation
That phase of a muscle twitch during which a muscle returns to a resting position.		01.9710