| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID651487 | Change in plasma triglycerides in diet-induced obese mice over 30 days at 100 mg/kg ip | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651535 | Effect on SF1(NR5A1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651492 | Change in plasma leptin in diet-induced obese mice over 30 days at 100 mg/kg ip | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651516 | Effect on TR2(NR2C1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID1722006 | Agonist activity at Rev-Erb alpha (unknown origin) by FRET assay | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17
| The transcriptional repressor REV-ERB as a novel target for disease. |
| AID651523 | Effect on ESR1(NR3A1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651512 | Effect on HNF4G(NR2A2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651477 | Plasma concentration after 2 hours at 100mg/kg ip dose (10mg/ml solution in 15% Cremophor) | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651526 | Effect on ERR2(NR3B2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651521 | Effect on TFCOUP2(NR2F2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651482 | Decreased expression of REV-ERB responsive gene Srebf1 in mouse liver after 6 days at 100 mg/kg | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID671973 | Plasma concentration in C57BL/6 mouse at 50 mg/kg, ip measured after 2 hrs by LC-MS/MS analysis | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13
| Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα. |
| AID651539 | Effect on GCNF(NR6A1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651489 | Change in plasma NEFA (non-esterified fatty acids) in diet-induced obese mice over 30 days at 100 mg/kg ip | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651524 | Effect on ESR2(NR3A2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651491 | Change in plasma insulin in diet-induced obese mice over 30 days at 100 mg/kg ip | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651536 | Effect on CPF(NR5A2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651498 | Effect on RARG(NR1B3) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID747988 | Binding affinity to LXRalpha (unknown origin) by radioligand displacement assay | 2013 | Journal of medicinal chemistry, Jun-13, Volume: 56, Issue:11
| Optimized chemical probes for REV-ERBα. |
| AID651500 | Effect on PPARD(NR1C2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651466 | Increased REV-ERB-alpha LBD dependent repressor activity in HEK293 cell reporter assay | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651514 | Effect on RXRB(NR2B2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651504 | Effect on RORG(NR1F3) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651508 | Effect on VDR(NR1I1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651509 | Effect on PXR(NR1I2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651518 | Effect on TLX(NR2E1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651483 | Decreased expression of REV-ERB responsive gene Serpine1 in mouse liver after 6 days at 100 mg/kg | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651531 | Effect on AR(NR3C4) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID671976 | Ratio of drug uptake in brain to plasma of C57BL/6 mouse at 50 mg/kg, ip relative to control | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13
| Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα. |
| AID651470 | Recruitment of co-repressor NcoR1 to REV-ERB-alpha | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651499 | Effect on PPARA(NR1C1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID671970 | Agonist activity at Rev-Erbalpha expressed in HEK293 cells coexpressing Gal4 ligand binding domain assessed as inhibition of transcription after 24 hrs by dual-Glo luciferase assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13
| Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα. |
| AID651515 | Effect on RXRG(NR2B3) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651511 | Effect on HNF4A(NR2A1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651530 | Effect on PGR(NR3C3) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651488 | Change in total plasma cholesterol in diet-induced obese mice over 30 days at 100 mg/kg ip | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID747989 | Agonist activity at biotinylated REV-ERBalpha (unknown origin) assessed as biotinylated PGC1-beta peptide recruitment after 20 mins by Greiner assay | 2013 | Journal of medicinal chemistry, Jun-13, Volume: 56, Issue:11
| Optimized chemical probes for REV-ERBα. |
| AID651525 | Effect on ERR1(NR3B1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651472 | Plasma concentration after 2 hours at 10mg/kg ip dose (10mg/ml suspension in 10%DMSO/10%Tween80) | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651513 | Effect on RXRA(NR2B1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651495 | Effect on THRB(NR1A2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651471 | Plasma concentration after 1 hour at 10mg/kg ip dose (10mg/ml suspension in 10%DMSO/10%Tween80) | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651519 | Effect on PNR(NR2E3) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651490 | Change in plasma glucose in diet-induced obese mice over 30 days at 100 mg/kg ip | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID671975 | Ratio of drug uptake in brain to plasma of C57BL/6 mouse at 10 mg/kg, ip measured after 2 hrs by LC-MS/MS analysis relative to control | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13
| Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα. |
| AID651532 | Effect on GFRP1(NR4A1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651494 | Effect on THRA(NR1A1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651467 | Increased REV-ERB-beta LBD dependent repressor activity in HEK293 cell reporter assay | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651475 | Brain concentration after 8 hours at 10mg/kg ip dose (10mg/ml suspension in 10%DMSO/10%Tween80) | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651474 | Plasma concentration after 8 hours at 10mg/kg ip dose (10mg/ml suspension in 10%DMSO/10%Tween80) | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651527 | Effect on ERR3(NR3B3) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651522 | Effect on EAR2(NR2F6) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID671971 | Plasma concentration in C57BL/6 mouse at 10 mg/kg, ip measured after 2 hrs by LC-MS/MS analysis | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13
| Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα. |
| AID671968 | Agonist activity at Rev-Erbalpha expressed in HEK293 cells coexpressing BamII promoter assessed as repression of transcription after 24 hrs by dual-Glo luciferase assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13
| Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα. |
| AID651473 | Plasma concentration after 4 hours at 10mg/kg ip dose (10mg/ml suspension in 10%DMSO/10%Tween80) | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651517 | Effect on TR4(NR2C2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651496 | Effect on RARA(NR1B1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID747984 | Agonist activity at REV-ERBalpha in human U2OS cells assessed as suppression of BMAL1 expression at 20 uM after 40 hrs by luciferase reporter gene assay relative to DMSO-treated control | 2013 | Journal of medicinal chemistry, Jun-13, Volume: 56, Issue:11
| Optimized chemical probes for REV-ERBα. |
| AID651507 | Effect on BAR(NR1H4) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651486 | Increased weight loss in diet-induced obese mice over 30 days at 100 mg/kg ip compared to vehicle control | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651478 | Plasma concentration after 8 hours at 100mg/kg ip dose (10mg/ml solution in 15% Cremophor) | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651510 | Effect on CAR(NR1I3) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID671972 | Drug uptake in C57BL/6 mouse brain at 10 mg/kg, ip measured after 2 hrs by LC-MS/MS analysis | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13
| Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα. |
| AID651537 | Effect on DAX1(NR0B1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651481 | Decreased expression of REV-ERB responsive gene Cyp7a1 in mouse liver after 6 days at 100 mg/kg | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651493 | Change in plasma IL-6 in diet-induced obese mice over 30 days at 100 mg/kg ip | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651505 | Effect on LXRB(NR1H2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID671969 | Agonist activity at Rev-Erbalpha expressed in HEK293 cells coexpressing BamII promoter assessed as repression of transcription at 10 uM after 24 hrs by dual-Glo luciferase assay relative to control | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13
| Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα. |
| AID651497 | Effect on RARB(NR1B2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651534 | Effect on NOR1(NR4A3) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651506 | Effect on LXRA(NR1H3) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651520 | Effect on TFCOUP1(NR2F1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651502 | Effect on RORA(NR1F1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID747983 | Agonist activity at REV-ERBalpha in human U2OS cells assessed as delay of peak of second cycle at 20 uM by luciferase reporter gene assay relative to DMSO-treated control | 2013 | Journal of medicinal chemistry, Jun-13, Volume: 56, Issue:11
| Optimized chemical probes for REV-ERBα. |
| AID651468 | REV-ERB-alpha mediated transcriptional suppression at Bmal1 promoter in HEK293 cell reporter assay | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651503 | Effect on RORB(NR1F2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID747991 | Agonist activity at biotinylated REV-ERBalpha (unknown origin) assessed as increase in biotinylated NCOR peptide recruitment after 1 hr by FRET assay | 2013 | Journal of medicinal chemistry, Jun-13, Volume: 56, Issue:11
| Optimized chemical probes for REV-ERBα. |
| AID651528 | Effect on GCR(NR3C1) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651469 | Dissociation constant for binding to REV-ERB-alpha by circular dichroism | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651538 | Effect on SHP(NR0B2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651501 | Effect on PPARG(NR1C3) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID747990 | Agonist activity at biotinylated REV-ERBalpha (unknown origin) assessed as increase in biotinylated NCOR peptide recruitment at 10 mM after 1 hr by FRET assay relative to control | 2013 | Journal of medicinal chemistry, Jun-13, Volume: 56, Issue:11
| Optimized chemical probes for REV-ERBα. |
| AID651533 | Effect on NURR1(NR4A2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID671974 | Drug uptake in C57BL/6 mouse brain at 50 mg/kg, ip measured after 8 hrs by LC-MS/MS analysis | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13
| Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα. |
| AID651529 | Effect on MCR(NR3C2) dependent reporter activity in HEK293 cells at 20 uM | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID651476 | Brain concentration after 2 hours at 10mg/kg ip dose (10mg/ml suspension in 10%DMSO/10%Tween80) | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID1346801 | Human Rev-Erb-alpha (1D. Rev-Erb receptors) | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| AID1346747 | Human Rev-Erb-beta (1D. Rev-Erb receptors) | 2012 | Nature, Mar-29, Volume: 485, Issue:7396
| Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |