| Assay ID | Title | Year | Journal | Article |
|---|
| AID421311 | Antiproliferative activity against human NCI-H460 cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID421303 | Antiproliferative activity against human A375 cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID697736 | Antiviral activity against HSV1 strain F ATCC VR733 infected in african green monkey Vero cells assessed as inhibition of cytopathic effect after 48 hrs by plaque reduction assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID421301 | Oral bioavailability in rat | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID697723 | Antiviral activity against HSV1 infected herpes simplex keratitis New zealand rabbit model assessed as reduction in viral DNA level in corneal sample at 0.025% to 0.1% administered twice daily as gel 24 hrs post inoculation measured on day 9 post infectio | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID421308 | Antiproliferative activity against human SK-MEL-5 cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID421307 | Antiproliferative activity against human SW620 cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID697728 | Selectivity index, ratio of CC50 for african green monkey Vero cells to EC50 for HSV2 strain 333 infected in african green monkey Vero cells | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID421312 | Antiproliferative activity against human HCT15 cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID697724 | Antiviral activity against HSV1 infected herpes simplex keratitis New zealand rabbit model assessed as reduction in corneal epithelia involvement score at 0.025% to 0.1% administered twice daily as gel 24 hrs post inoculation measured on day 9 post infect | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID421305 | Antiproliferative activity against human MCF7 cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID421309 | Antiproliferative activity against human PC3 cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID421310 | Antiproliferative activity against human MDA-MB-231 cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID697734 | Antiviral activity against HSV2 strain 333 infected in african green monkey Vero cells assessed as inhibition of cytopathic effect after 48 hrs by plaque reduction assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID697722 | Antiviral activity against HSV1 infected herpes simplex keratitis New zealand rabbit model assessed as reduction in viral DNA level in corneal sample compound administered twice daily as gel 24 hrs post inoculation measured on day 9 post infection by RT-P | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID697737 | Cytotoxicity against african green monkey Vero cells assessed as inhibition of cell viability after 48 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID697733 | Antiviral activity against HSV1 strain F ATCC VR733 infected in african green monkey Vero cells assessed as inhibition of cytopathic effect at 4 uM after 48 hrs by plaque reduction assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID697735 | Cytotoxicity against human MRC5 cells after 48 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID421316 | Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screening | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID697732 | Antiviral activity against HSV2 strain 333 infected in african green monkey Vero cells assessed as inhibition of cytopathic effect at 4 uM after 48 hrs by plaque reduction assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID421314 | Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screening | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID421304 | Antiproliferative activity against human LNCAP cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID421313 | Antiproliferative activity against human K562 cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID697727 | Antiviral activity against HSV1 infected herpes simplex keratitis New zealand rabbit model at 0.025% to 0.1% administered twice daily as gel 24 hrs post inoculation measured on day 9 post infection | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID421315 | Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screening | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID421302 | Binding affinity to pig spleen Hsp90 ATPase pocket by Bradford assay | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID421306 | Antiproliferative activity against human HT-29 cells after 72 to 144 hrs by cyquant DNA dye method | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| AID697729 | Selectivity index, ratio of CC50 for african green monkey Vero cells to EC50 for HSV1 strain F ATCC VR733 infected in african green monkey Vero cells | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. |
| AID421300 | Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screening | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |