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acetazolamide and Rheumatoid Arthritis

acetazolamide has been researched along with Rheumatoid Arthritis in 8 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Research Excerpts

ExcerptRelevanceReference
"To observe the effect of acetazolamide (AZ) on the expressions of aquaporin 1 (AQP1) and AQP3 in fibroblast-like synoviocytes of rheumatoid arthritis (RAFLSs) and explore the roles of AQP1 and AQP3 in the development of rheumatoid arthritis (RA)."7.79[Effect of acetazolamide on AQP1 and AQP3 expressions in fibroblast-like synoviocytes of rheumatoid arthritis]. ( Jiang, H; Liu, J; Liu, Q; Xie, C; Yue, Y, 2013)
"Carbon monoxide (CO) is a gas endogenously produced in humans, reported to exhibit anti-inflammatory and cytoprotective effects at low concentration."5.51Synthesis and Evaluation of Carbonic Anhydrase Inhibitors with Carbon Monoxide Releasing Properties for the Management of Rheumatoid Arthritis. ( Angeli, A; Bartolucci, G; Berrino, E; Bozdag, M; Carta, F; di Cesare Mannelli, L; Ghelardini, C; Menicatti, M; Micheli, L; Milazzo, L; Nocentini, A; Supuran, CT; Vullo, D, 2019)
"To observe the effect of acetazolamide (AZ) on the expressions of aquaporin 1 (AQP1) and AQP3 in fibroblast-like synoviocytes of rheumatoid arthritis (RAFLSs) and explore the roles of AQP1 and AQP3 in the development of rheumatoid arthritis (RA)."3.79[Effect of acetazolamide on AQP1 and AQP3 expressions in fibroblast-like synoviocytes of rheumatoid arthritis]. ( Jiang, H; Liu, J; Liu, Q; Xie, C; Yue, Y, 2013)
"A 67-year-old woman and a 75-year-old woman taking carbonic anhydrase inhibitors for therapy of glaucoma and high doses of aspirin for therapy of arthritis developed severe acid-base imbalance and salicylate intoxication."3.66Toxicity of combined therapy with carbonic anhydrase inhibitors and aspirin. ( Anderson, CJ; Kaufman, PL; Sturm, RJ, 1978)
"Carbon monoxide (CO) is a gas endogenously produced in humans, reported to exhibit anti-inflammatory and cytoprotective effects at low concentration."1.51Synthesis and Evaluation of Carbonic Anhydrase Inhibitors with Carbon Monoxide Releasing Properties for the Management of Rheumatoid Arthritis. ( Angeli, A; Bartolucci, G; Berrino, E; Bozdag, M; Carta, F; di Cesare Mannelli, L; Ghelardini, C; Menicatti, M; Micheli, L; Milazzo, L; Nocentini, A; Supuran, CT; Vullo, D, 2019)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Bua, S2
Di Cesare Mannelli, L4
Vullo, D3
Ghelardini, C4
Bartolucci, G4
Scozzafava, A2
Supuran, CT4
Carta, F4
Akgul, O1
Angeli, A2
Alfawaz Altamimi, AS1
Berrino, E1
Milazzo, L1
Micheli, L2
Bozdag, M1
Nocentini, A2
Menicatti, M2
Lucarini, L1
Selleri, S1
Masini, E1
Gratteri, P1
Yue, Y1
Liu, J1
Liu, Q1
Jiang, H1
Xie, C1
Doita, M1
Terukina, M1
Mizuno, K1
Anderson, CJ1
Kaufman, PL1
Sturm, RJ1
Lipsitz, SR1

Other Studies

8 other studies available for acetazolamide and Rheumatoid Arthritis

ArticleYear
Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis.
    Journal of medicinal chemistry, 2017, 02-09, Volume: 60, Issue:3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbonic Anhydr

2017
Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis.
    Journal of medicinal chemistry, 2018, 06-14, Volume: 61, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbonic Anhydrase Inhibito

2018
Synthesis and Evaluation of Carbonic Anhydrase Inhibitors with Carbon Monoxide Releasing Properties for the Management of Rheumatoid Arthritis.
    Journal of medicinal chemistry, 2019, 08-08, Volume: 62, Issue:15

    Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Carbon Monoxide; Carbonic Anhydrase Inhibitors

2019
Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis.
    Journal of medicinal chemistry, 2020, 03-12, Volume: 63, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbonic Anhydrase Inhibito

2020
[Effect of acetazolamide on AQP1 and AQP3 expressions in fibroblast-like synoviocytes of rheumatoid arthritis].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2013, Volume: 29, Issue:11

    Topics: Acetazolamide; Adult; Aged; Aquaporin 1; Aquaporin 3; Arthritis, Rheumatoid; Female; Fibroblasts; Ge

2013
[A case report of systemic calcinosis associated with rheumatoid arthritis].
    Ryumachi. [Rheumatism], 1996, Volume: 36, Issue:3

    Topics: Acetazolamide; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Calcinosis; Carbonic Anhydrase

1996
Toxicity of combined therapy with carbonic anhydrase inhibitors and aspirin.
    American journal of ophthalmology, 1978, Volume: 86, Issue:4

    Topics: Acetazolamide; Acid-Base Imbalance; Aged; Arthritis, Rheumatoid; Aspirin; Carbonic Anhydrase Inhibit

1978
Methods for estimating the parameters of a linear model for ordered categorical data.
    Biometrics, 1992, Volume: 48, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Arthritis, Rheumatoid; Auranofin; Biometry; Cli

1992