metyrapone has been researched along with Rheumatoid Arthritis in 22 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Estimate the contribution of monocytes/macrophages to the disease process in rheumatoid arthritis (RA), by measuring the serum levels of the leucocyte-derived granular proteins: lysozyme, myeloperoxidase (MPO), lactoferrin and human neutrophil lipocalin (HNL)." | 3.70 | Serum lysozyme: a potential marker of monocyte/macrophage activity in rheumatoid arthritis. ( Arvidson, NG; Gudbjörnsson, B; Hâkansson, L; Hällgren, R; Torsteinsdóttir, I; Venge, P, 1999) |
| "Pregnanetriol excretion was lower (P less than ." | 2.37 | Low adrenal androgenic-anabolic steroids in women with rheumatoid arthritis (RA): gas-liquid chromatographic studies of RA patients and matched normal control women indicating decreased 11-deoxy-17-ketosteroid excretion. ( Jefferson, WE; Josipović, DB; Masi, AT, 1984) |
| "Metyrapone treatment increased the surface expression of CD35 and CD49f on eosinophils, but did not affect surface expression on neutrophils." | 1.30 | Enhanced expression of integrins and CD66b on peripheral blood neutrophils and eosinophils in patients with rheumatoid arthritis, and the effect of glucocorticoids. ( Arvidson, NG; Håkansson, L; Hällgren, R; Torsteinsdóttir, I, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (86.36) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KAPLAN, NM | 1 |
| DeANDRADE, JR | 1 |
| LOUYOT, P | 2 |
| GAUCHER, A | 2 |
| BENOIT, P | 2 |
| MONTET, Y | 1 |
| KERNOHAN, RJ | 1 |
| GOTH, E | 2 |
| GOERGENYI, G | 1 |
| FOEVENYI, J | 1 |
| SZANTO, E | 2 |
| SHIOKAWA, Y | 1 |
| FLEISHMAN, EV | 1 |
| KALLIOMAKI, JL | 1 |
| KARKI, NT | 1 |
| SAARIMAA, HA | 1 |
| TALA, E | 1 |
| Jasani, MK | 2 |
| Boyle, JA | 1 |
| Greig, WR | 1 |
| Dalakos, TG | 2 |
| Browning, MC | 1 |
| Thompson, A | 1 |
| Buchanan, WW | 2 |
| Masi, AT | 1 |
| Josipović, DB | 1 |
| Jefferson, WE | 1 |
| Torsteinsdóttir, I | 3 |
| Arvidson, NG | 3 |
| Hällgren, R | 3 |
| Håkansson, L | 3 |
| Gudbjörnsson, B | 1 |
| Venge, P | 1 |
| Giacovazzo, M | 3 |
| Nelson, JK | 1 |
| Mackay, JS | 1 |
| Sheridan, B | 1 |
| Weaver, JA | 1 |
| Ruvalcaba, RH | 1 |
| Waxman, SH | 1 |
| Tippit, DF | 1 |
| Kelley, VC | 1 |
| Görgényi, G | 1 |
| Fövényi, J | 1 |
| Sako, Y | 1 |
| Diver, MJ | 1 |
| Bell, AM | 1 |
| Ippolito, A | 2 |
| Babalamenti, G | 1 |
| Pagliari, M | 1 |
1 review available for metyrapone and Rheumatoid Arthritis
| Article | Year |
|---|---|
Low adrenal androgenic-anabolic steroids in women with rheumatoid arthritis (RA): gas-liquid chromatographic studies of RA patients and matched normal control women indicating decreased 11-deoxy-17-ketosteroid excretion.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Anab | 1984 |
21 other studies available for metyrapone and Rheumatoid Arthritis
| Article | Year |
|---|---|
ASSESSMENT OF PITUITARY ACTH SECRETORY CAPACITY WITH METOPIRONE: II. COMPARISON WITH OTHER TESTS.
Topics: Acromegaly; Adenoma; Adenoma, Chromophobe; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Art | 1963 |
PITUITARY-ADRENOCORTICAL RESERVE DURING CORTICOSTEROID THERAPY: A REPORT ON THE METHOPYRAPONE TEST IN TEN PATIENTS TAKING LONG-CONTINUED SMALL DOSES.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Biomedical Research; Met | 1964 |
[EXAMINATION OF THE HYPOTHALAMUS AND ADRENAL GLANDS IN THE COURSE OF CHRONIC POLYARTHRITIS FOLLOWING PROLONGED CORTICOTHERAPY].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Arthritis; Ar | 1964 |
[HYPOTHALAMO-HYPOPHYSO-ADRENAL FUNCTION FOLLOWING PROLONGED CORTICOTHERAPY STUDIED WITH THE METOPIRONE TEST].
Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Cortisone; Humans; Hypothalamo-Hypoph | 1964 |
METYRAPONE AND ACUTE ADRENAL INSUFFICIENCY.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Insufficiency; Arthritis; Arthritis, Rheumatoid; F | 1964 |
[ADRENOCORTICAL AND PITUITARY FUNCTION FOLLOWING PROTRACTED PREDNISOLONE TREATMENT].
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Biomedical Research; | 1964 |
ACTIVATION OF SUBCLINICAL RHEUMATIC ACTIVITY BY METOPIRONE ADMINISTRATION IN RHEUMATIC HEART DISEASE AND RHEUMATOID ARTHRITIS.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Arthritis, Rheumatoid; Conjunctiva; Diagnosis; Erythrocyte | 1964 |
[USE OF THE METOPIRONE TEST FOR THE INVESTIGATION OF THE PITUITARY AND CORTICO-ADRENAL FUNCTION IN PATIENTS UNDERGOING PROLONGED CORTICOSTEROID THERAPY].
Topics: Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Metyrapone; Mineralocortico | 1965 |
Pituitary corticotrophin (ACTH) production in rheumatoid arthritis tested indirectly with Metopiron (Su 4885).
Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Humans; Metyrapone | 1961 |
Corticosteroid-induced suppression of the hypothalamo-pituitary-adrenal axis: observations on patients given oral corticosteroids for rheumatoid arthritis.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adult; Arthritis, Rheumatoid; Blood Glucose; Female; Gluc | 1967 |
Monocyte activation in rheumatoid arthritis (RA): increased integrin, Fc gamma and complement receptor expression and the effect of glucocorticoids.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; CD18 Antigens; Female; Glucocorticoids; Human | 1999 |
Enhanced expression of integrins and CD66b on peripheral blood neutrophils and eosinophils in patients with rheumatoid arthritis, and the effect of glucocorticoids.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Neoplasm; Arthritis, Rheumatoid; Cell Adhesi | 1999 |
Serum lysozyme: a potential marker of monocyte/macrophage activity in rheumatoid arthritis.
Topics: Acute-Phase Proteins; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Arthritis, Rheumatoi | 1999 |
[Treatment of rheumatoid arthritis].
Topics: Adrenal Glands; Adrenal Insufficiency; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimalarial | 1975 |
Intermittent therapy with corticotrophin.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Arthritis, Rheumato | 1966 |
Response to metyrapone in children with rheumatic diseases.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Arthritis, Rheu | 1966 |
Adrenocortical and pituitary function following long-term prednisolone treatment.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Arthritis, Rheumatoid; Female; Huma | 1966 |
[Clinical studies on the stimulation and suppression of the pituitary-adrenocortical system. 3. Studies on the pituitary adrenocortical suppression after long-term glucocorticoid treatment].
Topics: 17-Hydroxycorticosteroids; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Arthriti | 1968 |
Some clinical observations on the diurnal rhythm of plasma cortisol (11-OHCS) in patients with rheumatoid arthritis treated with oral corticosteroid drugs.
Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Circadian Rhythm; | 1974 |
[Use of metopirone in the diagnosis of latent immuno-allergic disorders].
Topics: Arthritis, Rheumatoid; Humans; Hypersensitivity; Metyrapone | 1964 |
[Metopirone in the treatment of rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Humans; Metyrapone | 1965 |