alanine has been researched along with Rheumatoid Arthritis in 30 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to examine whether a Proline (Pro)-to-Alanine (Ala) exchange at codon 12 (Pro12Ala) polymorphism of the peroxisome proliferator-activated receptor-gamma (PPARγ) is associated with susceptibility to nonalcoholic fatty liver disease (NAFLD), rheumatoid arthritis (RA), and psoriatic arthritis (PsA)." | 4.90 | Meta-analysis of associations between the peroxisome proliferator-activated receptor-γ Pro12Ala polymorphism and susceptibility to nonalcoholic fatty liver disease, rheumatoid arthritis, and psoriatic arthritis. ( Bae, SC; Lee, YH; Song, GG, 2014) |
| "The development of rheumatoid arthritis is directly correlated with the disturbance of gut microbiome and its metabolites." | 1.91 | Metabonomics and 16S rRNA gene sequencing to study the therapeutic mechanism of Danggui Sini decoction on collagen-induced rheumatoid arthritis rats with Cold Bi syndrome. ( Cheng, B; Feng, LL; Guo, BJ; Guo, HW; He, Y; Huang, Z; Nong, YY; Qin, JH; Su, ZH; Wang, QY; Zhu, D, 2023) |
| " The known association between ACPA level and alanine at position 74 of HLA-DRβ1 in ACPA-positive RA was revisited to understand the phenotypic effect of allele-specific expression of HLA-DRB1 by modeling multivariate logistic regression with the genomic dosage or relative expression dosage of Ala-74 in 2 independent sets of 1,723 Korean RA patients with ACPA." | 1.62 | Allele-Specific Quantification of HLA-DRB1 Transcripts Reveals Imbalanced Allelic Expression That Modifies the Amino Acid Effects in HLA-DRβ1. ( Bae, SC; Bang, SY; Chun, S; Cui, J; Gu, KN; Ha, E; Kim, K; Lee, HS, 2021) |
| "Rheumatic diseases were IA (60%) and CTD (40%)." | 1.56 | Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune rheumatic diseases: a multicentric matched cohort study. ( Alvaro-Gracia, JM; Blanco, R; Carmona, L; Castrejón, I; Fernández Fernández, D; Fernandez-Nebro, A; Galindo, M; Gonzalez-Gay, MA; Lledó, A; Manrique-Arija, S; Martinez-Lopez, D; Mena Vázquez, N; Mera-Varela, A; Pablos, JL; Retuerto, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (16.67) | 18.7374 |
| 1990's | 6 (20.00) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 6 (20.00) | 24.3611 |
| 2020's | 10 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kobayashi, H | 1 |
| Hirai, Y | 1 |
| Aoki, A | 1 |
| Cellat, M | 1 |
| İşler, CT | 1 |
| Kutlu, T | 1 |
| Kuzu, M | 1 |
| Etyemez, M | 1 |
| Alakuş, H | 1 |
| Güvenç, M | 1 |
| He, Y | 1 |
| Cheng, B | 1 |
| Guo, BJ | 1 |
| Huang, Z | 1 |
| Qin, JH | 1 |
| Wang, QY | 1 |
| Feng, LL | 1 |
| Nong, YY | 1 |
| Zhu, D | 1 |
| Guo, HW | 1 |
| Su, ZH | 1 |
| Kim, TJ | 1 |
| Kim, ER | 1 |
| Hong, SN | 1 |
| Kim, YH | 1 |
| Lee, YC | 1 |
| Kim, HS | 1 |
| Kim, K | 2 |
| Chang, DK | 1 |
| Larsen, DN | 1 |
| Mikkelsen, CE | 1 |
| Kierkegaard, M | 1 |
| Bereta, GP | 1 |
| Nowakowska, Z | 1 |
| Kaczmarek, JZ | 1 |
| Potempa, J | 1 |
| Højrup, P | 1 |
| Souto-Carneiro, M | 1 |
| Tóth, L | 1 |
| Behnisch, R | 1 |
| Urbach, K | 1 |
| Klika, KD | 1 |
| Carvalho, RA | 1 |
| Lorenz, HM | 1 |
| Kim, JW | 1 |
| Jeong, Y | 1 |
| Park, SJ | 1 |
| Jin, H | 1 |
| Lee, J | 1 |
| Ju, JH | 1 |
| Ji, GE | 1 |
| Park, SH | 2 |
| Pablos, JL | 1 |
| Galindo, M | 1 |
| Carmona, L | 1 |
| Lledó, A | 1 |
| Retuerto, M | 1 |
| Blanco, R | 1 |
| Gonzalez-Gay, MA | 1 |
| Martinez-Lopez, D | 1 |
| Castrejón, I | 1 |
| Alvaro-Gracia, JM | 1 |
| Fernández Fernández, D | 1 |
| Mera-Varela, A | 1 |
| Manrique-Arija, S | 1 |
| Mena Vázquez, N | 1 |
| Fernandez-Nebro, A | 1 |
| Chun, S | 1 |
| Bang, SY | 1 |
| Ha, E | 1 |
| Cui, J | 1 |
| Gu, KN | 1 |
| Lee, HS | 1 |
| Bae, SC | 2 |
| Li, J | 2 |
| Liu, HH | 1 |
| Yin, XD | 1 |
| Li, CC | 1 |
| Wang, J | 1 |
| Chen, J | 2 |
| Cheng, W | 1 |
| Wang, Y | 1 |
| Shen, X | 1 |
| Su, A | 1 |
| Gan, D | 1 |
| Ke, L | 1 |
| Liu, G | 1 |
| Lin, J | 1 |
| Li, L | 1 |
| Bai, X | 1 |
| Zhang, P | 1 |
| Takahashi, S | 1 |
| Saegusa, J | 1 |
| Onishi, A | 1 |
| Morinobu, A | 1 |
| Lee, YH | 1 |
| Song, GG | 1 |
| Byun, JK | 1 |
| Moon, SJ | 1 |
| Jhun, JY | 1 |
| Kim, EK | 1 |
| Park, JS | 1 |
| Youn, J | 1 |
| Min, JK | 1 |
| Kim, HY | 1 |
| Cho, ML | 1 |
| Onaran, I | 1 |
| Tezcan, G | 1 |
| Ozgönenel, L | 1 |
| Cetin, E | 1 |
| Ozdemir, AT | 1 |
| Kanigür-Sultuybek, G | 1 |
| Savio, AS | 1 |
| Acosta, OR | 1 |
| Pérez, HG | 2 |
| Alvarez, YR | 1 |
| Chico, A | 1 |
| Ojeda, MO | 1 |
| Aguero, CA | 1 |
| Estévez, M | 1 |
| Nieto, GG | 1 |
| Hasegawa, M | 1 |
| Horiki, N | 1 |
| Tanaka, K | 1 |
| Wakabayashi, H | 1 |
| Tano, S | 1 |
| Katsurahara, M | 1 |
| Uchida, A | 1 |
| Takei, Y | 1 |
| Sudo, A | 1 |
| Campbell, J | 1 |
| Ciesielski, CJ | 1 |
| Hunt, AE | 1 |
| Horwood, NJ | 1 |
| Beech, JT | 1 |
| Hayes, LA | 1 |
| Denys, A | 1 |
| Feldmann, M | 1 |
| Brennan, FM | 1 |
| Foxwell, BM | 1 |
| Feitsma, AL | 1 |
| Worthington, J | 1 |
| van der Helm-van Mil, AH | 1 |
| Plant, D | 1 |
| Thomson, W | 1 |
| Ursum, J | 1 |
| van Schaardenburg, D | 1 |
| van der Horst-Bruinsma, IE | 1 |
| van Rood, JJ | 1 |
| Huizinga, TW | 1 |
| Toes, RE | 1 |
| de Vries, RR | 1 |
| Shido, F | 1 |
| Morimoto, K | 1 |
| Duffy, JM | 1 |
| Grimshaw, J | 1 |
| Guthrie, DJ | 1 |
| McNally, GM | 1 |
| Mollan, RA | 1 |
| Spedding, PL | 1 |
| Trocha-Grimshaw, J | 1 |
| Walker, B | 1 |
| Walsh, E | 1 |
| Seidl, C | 1 |
| Donner, H | 1 |
| Fischer, B | 1 |
| Usadel, KH | 1 |
| Seifried, E | 1 |
| Kaltwasser, JP | 1 |
| Badenhoop, K | 1 |
| Meshitsuka, S | 1 |
| Yamazaki, E | 1 |
| Inoue, M | 1 |
| Hagino, H | 1 |
| Teshima, R | 1 |
| Yamamoto, K | 1 |
| Saklatvala, J | 1 |
| Baba, S | 1 |
| Takahashi, T | 1 |
| Kasama, T | 1 |
| Shirasawa, H | 1 |
| Baboonian, C | 2 |
| Venables, PJ | 2 |
| Williams, DG | 1 |
| Williams, RO | 1 |
| Maini, RN | 2 |
| Gao, X | 1 |
| Gazit, E | 1 |
| Livneh, A | 1 |
| Stastny, P | 1 |
| Halliday, D | 1 |
| Pawlowski, T | 1 |
| Millman, G | 1 |
| Trnavský, K | 1 |
| Rovenský, J | 1 |
| Dimitrov, NV | 1 |
| Stjernholm, RL | 1 |
| Weir, DR | 1 |
2 reviews available for alanine and Rheumatoid Arthritis
| Article | Year |
|---|---|
COVID-19 illness and autoimmune diseases: recent insights.
Topics: Adenosine Monophosphate; Alanine; Angiotensin-Converting Enzyme 2; Arthritis, Rheumatoid; Autoimmune | 2021 |
Meta-analysis of associations between the peroxisome proliferator-activated receptor-γ Pro12Ala polymorphism and susceptibility to nonalcoholic fatty liver disease, rheumatoid arthritis, and psoriatic arthritis.
Topics: Alanine; Arthritis, Psoriatic; Arthritis, Rheumatoid; Genetic Predisposition to Disease; Humans; Non | 2014 |
1 trial available for alanine and Rheumatoid Arthritis
| Article | Year |
|---|---|
The efficacy of rebamipide add-on therapy in arthritic patients with COX-2 selective inhibitor-related gastrointestinal events: a prospective, randomized, open-label blinded-endpoint pilot study by the GLORIA study group.
Topics: Alanine; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; E | 2013 |
27 other studies available for alanine and Rheumatoid Arthritis
| Article | Year |
|---|---|
COVID-19 survivors with calcineurin-inhibitors-treated rheumatoid arthritis.
Topics: Adenosine Monophosphate; Alanine; Arthritis, Rheumatoid; Calcineurin; Calcineurin Inhibitors; COVID- | 2022 |
Investigation of the effects of safranal on the experimentally created rheumatoid arthritis model in rats.
Topics: Alanine; Animals; Antioxidants; Arthritis, Experimental; Arthritis, Rheumatoid; Aspartate Aminotrans | 2022 |
Metabonomics and 16S rRNA gene sequencing to study the therapeutic mechanism of Danggui Sini decoction on collagen-induced rheumatoid arthritis rats with Cold Bi syndrome.
Topics: Alanine; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Butyric Acid; Collagen; Drugs, Chi | 2023 |
Effectiveness of acid suppressants and other mucoprotective agents in reducing the risk of occult gastrointestinal bleeding in nonsteroidal anti-inflammatory drug users.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cohort Studies | 2019 |
Citrullinome of
Topics: Alanine; Arthritis, Rheumatoid; Bacterial Outer Membrane; Bacterial Proteins; Catalytic Domain; Chro | 2020 |
Differences in the serum metabolome and lipidome identify potential biomarkers for seronegative rheumatoid arthritis versus psoriatic arthritis.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Arthritis, Psoriatic; Arthritis, Rhe | 2020 |
Influence of proton pump inhibitor or rebamipide use on gut microbiota of rheumatoid arthritis patients.
Topics: Alanine; Arthritis, Rheumatoid; Bacteria; DNA, Bacterial; Enzyme Inhibitors; Female; Gastrointestina | 2021 |
Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune rheumatic diseases: a multicentric matched cohort study.
Topics: Adenosine Monophosphate; Age Factors; Aged; Alanine; Antiviral Agents; Arthritis, Psoriatic; Arthrit | 2020 |
Allele-Specific Quantification of HLA-DRB1 Transcripts Reveals Imbalanced Allelic Expression That Modifies the Amino Acid Effects in HLA-DRβ1.
Topics: Alanine; Alleles; Anti-Citrullinated Protein Antibodies; Arthritis, Rheumatoid; Asian People; Gene D | 2021 |
Notch-1 and Notch-3 Mediate Hypoxia-Induced Activation of Synovial Fibroblasts in Rheumatoid Arthritis.
Topics: Adult; Aged; Alanine; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Azepines; Female; Fib | 2021 |
Biomarkers identified by serum metabolomic analysis to predict biologic treatment response in rheumatoid arthritis patients.
Topics: Abatacept; Alanine; Aminobutyrates; Antirheumatic Agents; Area Under Curve; Arthritis, Rheumatoid; B | 2019 |
Rebamipide attenuates autoimmune arthritis severity in SKG mice via regulation of B cell and antibody production.
Topics: Alanine; Animals; Antibody Formation; Arthritis, Experimental; Arthritis, Rheumatoid; Autoimmune Dis | 2014 |
The Val762Ala polymorphism in the poly(ADP-ribose) polymerase-1 gene is not associated with susceptibility in Turkish rheumatoid arthritis patients.
Topics: Adult; Aged; Alanine; Amino Acid Substitution; Arthritis, Rheumatoid; DNA Mutational Analysis; Femal | 2009 |
Enhancement of the inhibitory effect of an IL-15 antagonist peptide by alanine scanning.
Topics: Alanine; Amino Acid Sequence; Arthritis, Rheumatoid; Cell Line; Chromatography, High Pressure Liquid | 2012 |
A novel mechanism for TNF-alpha regulation by p38 MAPK: involvement of NF-kappa B with implications for therapy in rheumatoid arthritis.
Topics: 3' Untranslated Regions; Adenoviridae; Alanine; Arthritis, Rheumatoid; Aspartic Acid; Cell Line; Cel | 2004 |
Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development.
Topics: Alanine; Alleles; Arginine; Arthritis, Rheumatoid; Aspartic Acid; Child; Cohort Studies; Epitopes; F | 2007 |
Amino acid transport in human tonsillar lymphocytes with regard to patient's age and tonsillar diseases.
Topics: Adult; Age Factors; Alanine; Amino Acids; Arthritis, Rheumatoid; B-Lymphocytes; Biological Transport | 1984 |
1H-nuclear magnetic resonance studies of human synovial fluid in arthritic disease states as an aid to confirming metabolic activity in the synovial cavity.
Topics: Acetates; Alanine; Arthritis; Arthritis, Rheumatoid; Diagnosis, Differential; Humans; Hyaluronic Aci | 1993 |
CTLA4 codon 17 dimorphism in patients with rheumatoid arthritis.
Topics: Abatacept; Adult; Aged; Alanine; Antigens, CD; Antigens, Differentiation; Arthritis, Rheumatoid; Cod | 1998 |
Nuclear magnetic resonance studies of synovial fluids from patients with rheumatoid arthritis and osteoarthritis.
Topics: Alanine; Arthritis, Rheumatoid; Biomarkers; Diagnosis, Differential; Female; Humans; Lactic Acid; Ma | 1999 |
Hydrolysis of the elastase substrate succinyltrialanine nitroanilide by a metal-dependent enzyme in rheumatoid synovial fluid.
Topics: Adult; Aged; Alanine; Arthritis, Rheumatoid; Chromatography, Gel; Edetic Acid; Electrophoresis, Poly | 1977 |
Identification of two novel amyloid A protein subsets coexisting in an individual patient of AA-amyloidosis.
Topics: Alanine; Amino Acid Sequence; Amyloid; Amyloidosis; Arthritis, Rheumatoid; Female; Humans; Middle Ag | 1992 |
Cross reaction of antibodies to a glycine/alanine repeat sequence of Epstein-Barr virus nuclear antigen-1 with collagen, cytokeratin, and actin.
Topics: Actins; Alanine; Amino Acid Sequence; Antibodies, Viral; Antigens, Viral; Arthritis, Rheumatoid; Aut | 1991 |
Rheumatoid arthritis in Israeli Jews: shared sequences in the third hypervariable region of DRB1 alleles are associated with susceptibility.
Topics: Alanine; Alleles; Amino Acid Sequence; Arthritis, Rheumatoid; Genetic Predisposition to Disease; Gly | 1991 |
Antibodies in rheumatoid arthritis react specifically with the glycine alanine repeat sequence of Epstein-Barr nuclear antigen-1.
Topics: Alanine; Amino Acid Sequence; Antibodies, Antinuclear; Antigens, Viral; Arthritis, Rheumatoid; Autoa | 1989 |
[Study on the nephrotoxicity of antirheumatic drugs. II. Effect of gold salts on the levels of enzymes in the urine].
Topics: Alanine; Aminopeptidases; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Gold; Kidney; L- | 1974 |
Metabolic deviations of polymorphonuclear leukocytes in rheumatoid arthritis.
Topics: Alanine; Amino Acids; Arthritis, Rheumatoid; Aspartic Acid; Blood Proteins; Carbon Isotopes; Glutama | 1969 |