tryptophan and Rheumatoid Arthritis

tryptophan has been researched along with Rheumatoid Arthritis in 86 studies

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199050 (58.14)18.7374
1990's4 (4.65)18.2507
2000's8 (9.30)29.6817
2010's11 (12.79)24.3611
2020's13 (15.12)2.80

Authors

AuthorsStudies
Ji, JD; Jo, S; Kim, SY; Kim, TH; Oh, Y; Park, R; Park, SH1
Chang, Y; Han, P; Jia, C; Li, S; Wang, X; Wang, Y; Wei, W; Yang, X; Zhang, B; Zhao, Y1
Chang, Y; Jia, C; Li, S; Wang, X; Wang, Y; Wei, W; Yang, X; Zhang, B; Zhao, Y1
Chen, Q; Chen, X; Dai, M; Li, Y; Wang, M; Wang, Z; Wu, B; Xu, X; Xu, Y1
Cai, X; Cong, S; Gu, Y; Luo, L; Ma, X; Meng, Y; Wang, L; Zhang, C1
Bao, Y; Huang, X; Jin, Y; Lin, F; Lu, L; Ma, Y; Ren, H; Tan, L; Wang, F; Wu, L; Xie, X; Zhang, Y1
Adam, I; Kaul, NC; Lorenz, HM; Mohapatra, SR; Opitz, CA; Tretter, T; Tucher, C; Tykocinski, LO1
Clanchy, FI; Huang, YS; Ogbechi, J; Stone, TW; Topping, LM; Williams, RO1
Chu, SH; Clish, C; Costenbader, KH; Cui, J; Deane, KD; Edison, JD; Feser, ML; Karlson, EW; Kelmenson, LB; Lasky-Su, J; Lu, B; Mewshaw, EA; Moss, L; Sparks, JA; Speyer, CB; Tedeschi, SK1
Chakraborty, A; Chatterjee, SK; Dasgupta, AK1
Brown, J; Morel, L; Robusto, B1
Gerli, R; Grohmann, U; Pallotta, MT; Panfili, E1
Coras, R; Corominas, H; Diaz-Torne, C; Gil-Alabarse, P; Guma, M; Murillo-Saich, JD; Ortiz, MA; Pedersen, A; Vidal, S1
Ciciarello, M; Curti, A; Evangelisti, C; Jandus, C; Laury-Kleintop, L; Lecciso, M; Lemoli, RM; Metz, R; Očadlíková, D; Prendergast, GC; Romero, P; Salvestrini, V; Trabanelli, S1
DuHadaway, JB; Gilmour, S; Mandik-Nayak, L; Muller, AJ; Pigott, E; Prendergast, GC1
Chatterjee, S; Langford, CA; Tamaki, H1
Ju, JH; Jung, BH; Jung, SM; Kang, KY; Lee, SH; Park, SH1
Alam, K; Arfat, MY; Arif, Z; Chaturvedi, SK1
Ärlestig, L; Rantapää-Dahlqvist, S; Surowiec, I; Trygg, J1
Adam, I; Bohnen, A; Gay, S; Kaul, NC; Krienke, S; Lauffer, AM; Löhning, M; Lorenz, HM; Mohapatra, SR; Neidhart, M; Oezen, I; Opitz, CA; Platten, M; Saikali, P; Tretter, T; Tykocinski, LO1
Flaig, W; Galle, PR; Klingel, R; Lingg, G; Schönhals, E; Schorn, C; Schwarting, A; Thomaidis, T1
Mandik-Nayak, L; Muller, AJ; Prendergast, GC1
Chen, SY; Jou, IM; Lai, MD; Lee, CH; Lin, CC; Shiau, AL; Wang, CR; Weng, CT; Wu, CL; Yo, YT1
Mete, G; Ozkan, Y; Sepici, V; Sepici-Dincel, A; Simsek, B1
Del Bufalo, A; Del Papa, N; Filippini, P; Locatelli, F; Rutella, S; Sambataro, D1
Hirata, N; Kuriyama, T; Yamawaki, N1
Fuchs, D; Herold, M; Kaser, S; Ledochowski, M; Mur, E; Neurauter, G; Schroecksnadel, K1
BETT, IM3
SPIERA, H1
BROWN, RR; FLINN, JH; PRICE, JM; YESS, N1
HAWKINS, GR; MAZZARELLA, M; ZIPKIN, I1
PINALS, RS1
BEETHAM, W; FISCHER, S; SCHROHENLOHER, R1
Darlington, LG; Forrest, CM; Kennedy, A; Stone, TW; Stoy, N1
Fisher, SA; Grumley, JA; Kingsley, GH; Lad, B; Steer, S1
Egawa, H; Goto, T; Hamada, D; Inoue, H; Itakura, M; Kubo, T; Matsui, Y; Nakano, S; Shinomiya, F; Takata, Y; Yasui, N1
Duftner, C; Fuchs, D; Schirmer, M; Schroecksnadel, K; Winkler, C; Wirleitner, B1
Cao, Q; Ji, F; Liu, Q; Matsushima, K; Wang, Y; Zhang, JZ; Zhang, Y; Zhu, L1
West, GB1
Podell, RN1
Laurent, MR; Panayi, GS1
Forst, MB; Rand, SA1
Harley, JB; Malone, CC; Williams, RC1
Corlett, L; Deshpande, S; Driscoll, PC; Hawke, S; Matsuo, H; Nicolle, M; Spack, E; Willcox, N; Wordsworth, P1
Allegri, G; Bertazzo, A; Bertazzolo, N; Costa, CV; Pianon, M; Pozzuoli, A; Punzi, L1
McArthur, JN2
Aylward, M2
Eberl, R; Partsch, G; Schwarzer, C; Tausch, G1
Sadek, IA1
Dickerson, JW; Labadarios, D; McKenzie, DY; Parke, DV1
Aylward, M; Maddock, J; Parker, RJ; Wheeldon, R1
Aylward, M; Holly, F; Maddock, J; Rees, P1
Haslock, I1
Igari, T1
Chiancone, FM1
Taylor, WM1
Madsen, BW; Selley, ML; Thomas, J1
Broadhurst, AD1
Igari, T; Obara, K; Ono, S; Toba, Y2
Sorenson, JR1
Carreira, P; Heyes, MP; Silver, RM; Sutherland, SE1
Malek-Ahmadi, P1
Miyamoto, T; Takahashi, K; Yoshinoya, S; Yoshizawa, H1
Igari, T; Shimamura, T; Tsuchizawa, M1
Aylward, M; Maddock, J3
Houpt, JB; Hunt, M; Ogryzlo, MA1
Louis, R1
Pasquariello, G; Tenconi, LT1
Dawkins, PD; McArthur, JN; Smith, MJ2
Jaffe, IA2
Bruckner, FE; Chamberlain, MA; Lakatos, C; Smith, HG1
Igari, T; Tsuchizawa, M1
Forbes, JC; Nakoneczna, I; Rogers, KS1
Manzini, A; Marcolongo, R1
Dawkins, PD; Hamilton, EB; McArthur, JN; Smith, MJ1
Brown, JH; Mackey, HK1
Tsuchizawa, M1

Reviews

12 review(s) available for tryptophan and Rheumatoid Arthritis

ArticleYear
The bridge of the gut-joint axis: Gut microbial metabolites in rheumatoid arthritis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Arthritis, Rheumatoid; Bile Acids and Salts; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Tryptophan

2022
IDO activation, inflammation and musculoskeletal disease.
    Experimental gerontology, 2020, Volume: 131

    Topics: Animals; Arthritis, Rheumatoid; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Male; Mice; Musculoskeletal Diseases; Osteoporosis; Rats; Tryptophan

2020
Intestinal Dysbiosis and Tryptophan Metabolism in Autoimmunity.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Autoimmunity; Bacteria; Dysbiosis; Gastrointestinal Microbiome; Humans; Intestines; Lupus Erythematosus, Systemic; Multiple Sclerosis; Tryptophan

2020
Amino Acid Metabolism in Rheumatoid Arthritis: Friend or Foe?
    Biomolecules, 2020, 09-04, Volume: 10, Issue:9

    Topics: Animals; Arginine; Arthritis, Rheumatoid; Humans; Kynurenine; Microbiota; Serotonin; Tryptophan

2020
Eosinophilia in Rheumatologic/Vascular Disorders.
    Immunology and allergy clinics of North America, 2015, Volume: 35, Issue:3

    Topics: Arthritis, Rheumatoid; Churg-Strauss Syndrome; Eosinophilia; Eosinophilia-Myalgia Syndrome; Eosinophils; Fasciitis; Humans; Muscular Dystrophies, Limb-Girdle; Tryptophan

2015
Emerging concepts on inhibitors of indoleamine 2,3-dioxygenase in rheumatic diseases.
    Current medicinal chemistry, 2012, Volume: 19, Issue:31

    Topics: Animals; Arthritis, Rheumatoid; Enzyme Inhibitors; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lupus Erythematosus, Systemic; Rheumatic Diseases; Scleroderma, Systemic; Sjogren's Syndrome; Tryptophan

2012
Immusorba TR and PH.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2003, Volume: 7, Issue:1

    Topics: Absorption; Acetylcholine; Arthritis, Rheumatoid; Autoantibodies; Biocompatible Materials; Clinical Trials as Topic; Equipment Design; Equipment Safety; Guillain-Barre Syndrome; Humans; Immunosorbent Techniques; Immunosorbents; Lupus Erythematosus, Systemic; Myasthenia Gravis; Phenylalanine; Sensitivity and Specificity; Tryptophan

2003
The 'tomato effect' in clinical nutrition. New treatments languishing on the vine?
    Postgraduate medicine, 1984, Volume: 76, Issue:8

    Topics: Adult; Arthritis, Rheumatoid; Aspirin; Attitude to Health; Cardiovascular Diseases; Child; Colchicine; Coronary Disease; Diet; Drug Evaluation; Eczema; Female; Fish Oils; Folic Acid; Food Hypersensitivity; Gold; Gout; Humans; Hypoglycemia; Magnesium; Sleep; Tryptophan; Uterine Cervical Dysplasia

1984
Biochemical parameters in the assessment of anti-inflammatory drugs--a review.
    Agents and actions. Supplements, 1980, Volume: 7

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Proteins; Blood Sedimentation; C-Reactive Protein; Ceruloplasmin; Clinical Trials as Topic; Copper; Female; Fibrinogen; Gold; Haptoglobins; Humans; Immunoglobulins; Penicillamine; Rheumatoid Factor; Sulfhydryl Compounds; Tryptophan

1980
A review of possible mechanisms of action of the antirheumatic drug, alclofenac.
    Current medical research and opinion, 1975, Volume: 3, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Binding, Competitive; Blood Proteins; Catecholamines; Gastrointestinal Hormones; Histamine; Humans; Oxidative Phosphorylation; Phenylacetates; Prostaglandins; Protein Binding; Rats; Receptors, Drug; Serotonin; Serum Albumin; Sheep; Sulfhydryl Compounds; Terminology as Topic; Tryptophan

1975
The pharmacological consequences of the binding of anti-rheumatic drugs to plasma proteins in the treatment of rheumatoid arthritis.
    Agents and actions, 1979, Volume: 9, Issue:2

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Binding, Competitive; Blood Proteins; Humans; Kinetics; Protein Binding; Salicylates; Serum Albumin; Tryptophan

1979
The antivitamin B 6 effect of penicillamine: clinical and immunological implications.
    Advances in biochemical psychopharmacology, 1972, Volume: 4

    Topics: Antibody Formation; Arthritis, Rheumatoid; Drug Antagonism; Drug Interactions; Humans; Immunosuppression Therapy; Kynurenine; Penicillamine; Precipitin Tests; Pyridoxine; Rheumatoid Factor; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates

1972

Trials

4 trial(s) available for tryptophan and Rheumatoid Arthritis

ArticleYear
Biochemical parameters in the assessment of anti-inflammatory drugs--a review.
    Agents and actions. Supplements, 1980, Volume: 7

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Proteins; Blood Sedimentation; C-Reactive Protein; Ceruloplasmin; Clinical Trials as Topic; Copper; Female; Fibrinogen; Gold; Haptoglobins; Humans; Immunoglobulins; Penicillamine; Rheumatoid Factor; Sulfhydryl Compounds; Tryptophan

1980
The influence of alclofenac treatment on acute-phase proteins, plasma tryptophan, and erythrocyte sedimentation rate in patients with rheumatoid arthritis.
    Current medical research and opinion, 1975, Volume: 3, Issue:5

    Topics: Arthritis, Rheumatoid; Blood Proteins; Blood Sedimentation; C-Reactive Protein; Clinical Trials as Topic; Fibrinogen; Haptoglobins; Humans; Middle Aged; Penicillamine; Phenylacetates; Proteinuria; Pruritus; Rheumatoid Factor; Thrombocytopenia; Tryptophan

1975
The effect of alclofenac on clinical and laboratory measures of disease activity in rheumatoid arthritis: preliminary results.
    Current medical research and opinion, 1975, Volume: 3, Issue:5

    Topics: alpha 1-Antitrypsin; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Clinical Trials as Topic; Female; Glycoproteins; Humans; Immunoglobulins; Male; Middle Aged; Phenylacetates; Tryptophan

1975
Plasma-tryptophan levels in depression.
    Lancet (London, England), 1973, Apr-28, Volume: 1, Issue:7809

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Depression; Humans; Tryptophan

1973

Other Studies

71 other study(ies) available for tryptophan and Rheumatoid Arthritis

ArticleYear
B7-H3 regulates osteoclast differentiation via type I interferon-dependent IDO induction.
    Cell death & disease, 2021, 10-20, Volume: 12, Issue:11

    Topics: Animals; Antibodies, Neutralizing; Arthritis, Rheumatoid; B7 Antigens; Cell Differentiation; Enzyme Induction; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon Type I; Interferon-beta; Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Nitric Oxide Synthase Type II; Osteoclasts; Osteogenesis; Proto-Oncogene Proteins c-fos; RNA, Messenger; Signal Transduction; Stem Cells; Suppressor of Cytokine Signaling 1 Protein; Synovial Fluid; Tryptophan

2021
Tryptophan 2,3-dioxygenase 2 plays a key role in regulating the activation of fibroblast-like synoviocytes in autoimmune arthritis.
    British journal of pharmacology, 2022, Volume: 179, Issue:12

    Topics: Animals; Arthritis, Rheumatoid; Cell Movement; Cells, Cultured; Dioxygenases; Fibroblasts; Inflammation; Kynurenine; Rats; Synovial Membrane; Synoviocytes; Tryptophan; Tryptophan Oxygenase

2022
Activation of the kynurenine-aryl hydrocarbon receptor axis impairs the chondrogenic and chondroprotective effects of human umbilical cord-derived mesenchymal stromal cells in osteoarthritis rats.
    Human cell, 2023, Volume: 36, Issue:1

    Topics: Animals; Arthritis, Rheumatoid; Cell Differentiation; Chondrogenesis; Humans; Kynurenine; Ligands; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Osteoarthritis; Rats; Receptors, Aryl Hydrocarbon; Tryptophan; Umbilical Cord

2023
Saussurea involucrata oral liquid regulates gut microbiota and serum metabolism during alleviation of collagen-induced arthritis in rats.
    Phytotherapy research : PTR, 2023, Volume: 37, Issue:4

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cattle; Gastrointestinal Microbiome; Metabolomics; Rats; Saussurea; Tryptophan

2023
The prevalence and the effect of interferon -γ in the comorbidity of rheumatoid arthritis and depression.
    Behavioural brain research, 2023, 02-15, Volume: 439

    Topics: Animals; Arthritis, Rheumatoid; Comorbidity; Depression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Mice; Prevalence; Tryptophan

2023
Hypoxia decreases the T helper cell-suppressive capacity of synovial fibroblasts by downregulating IDO1-mediated tryptophan metabolism.
    Rheumatology (Oxford, England), 2020, 05-01, Volume: 59, Issue:5

    Topics: Arthritis, Rheumatoid; Blotting, Western; Cell Proliferation; Cells, Cultured; Chromatography, High Pressure Liquid; Coculture Techniques; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Flow Cytometry; Humans; Hypoxia; Immunomodulation; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interleukin-17; Male; Middle Aged; Reference Values; Synovial Membrane; T-Lymphocytes, Helper-Inducer; Tryptophan

2020
Circulating plasma metabolites and risk of rheumatoid arthritis in the Nurses' Health Study.
    Rheumatology (Oxford, England), 2020, 11-01, Volume: 59, Issue:11

    Topics: Adult; Age Factors; Arthritis, Rheumatoid; Body Mass Index; Butyric Acid; Caprylates; Carnitine; Case-Control Studies; Female; Humans; Incidence; Logistic Models; Metabolome; Methionine; Middle Aged; Military Personnel; Nurses; Phosphatidylethanolamines; Prospective Studies; Putrescine; Reproducibility of Results; Risk Factors; Smoking; Spermidine; Tryptophan; United States

2020
Label-free detection of thalassemia and other ROS impairing diseases.
    Medical & biological engineering & computing, 2020, Volume: 58, Issue:9

    Topics: Algorithms; Arthritis, Rheumatoid; Humans; Kynurenine; NAD; Oxidative Stress; Principal Component Analysis; Reactive Oxygen Species; ROC Curve; Spectrometry, Fluorescence; Spectrum Analysis, Raman; Thalassemia; Tryptophan

2020
Metabolomics profiling predicts outcome of tocilizumab in rheumatoid arthritis: an exploratory study.
    Metabolomics : Official journal of the Metabolomic Society, 2021, 08-16, Volume: 17, Issue:9

    Topics: 3-Hydroxybutyric Acid; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Metabolomics; Phenylalanine; Phosphorylcholine; Tryptophan

2021
The SOCS3-independent expression of IDO2 supports the homeostatic generation of T regulatory cells by human dendritic cells.
    Journal of immunology (Baltimore, Md. : 1950), 2014, Feb-01, Volume: 192, Issue:3

    Topics: Arthritis, Psoriatic; Arthritis, Rheumatoid; Cells, Cultured; Dendritic Cells; Dinoprostone; Enzyme Induction; Homeostasis; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Monocytes; Organ Specificity; Protein Biosynthesis; RNA Interference; RNA, Small Interfering; Spondylitis, Ankylosing; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; T-Lymphocytes, Regulatory; Transcription, Genetic; Tryptophan; Up-Regulation

2014
1-Methyl-tryptophan synergizes with methotrexate to alleviate arthritis in a mouse model of arthritis.
    Autoimmunity, 2014, Volume: 47, Issue:6

    Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Autoantibodies; Autoimmunity; Cytokines; Disease Models, Animal; Drug Synergism; Inflammation; Methotrexate; Mice; Tryptophan; Tryptophan Oxygenase

2014
Downregulation of Tryptophan-related Metabolomic Profile in Rheumatoid Arthritis Synovial Fluid.
    The Journal of rheumatology, 2015, Volume: 42, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Autoantibodies; Biomarkers; Blood Sedimentation; C-Reactive Protein; Chromatography, Liquid; Disease Progression; Down-Regulation; Female; Follow-Up Studies; Humans; Male; Mass Spectrometry; Middle Aged; Multivariate Analysis; Osteoarthritis; Sampling Studies; Sensitivity and Specificity; Severity of Illness Index; Statistics, Nonparametric; Synovial Fluid; Tryptophan

2015
Peroxynitrite-induced structural perturbations in human IgG: A physicochemical study.
    Archives of biochemistry and biophysics, 2016, 08-01, Volume: 603

    Topics: Arthritis, Rheumatoid; Calorimetry, Differential Scanning; Circular Dichroism; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin G; Inflammation; Light; Microscopy, Fluorescence; Oxygen; Peroxynitrous Acid; Protein Structure, Secondary; Scattering, Radiation; Sepharose; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Temperature; Tryptophan; Tyrosine

2016
Metabolite and Lipid Profiling of Biobank Plasma Samples Collected Prior to Onset of Rheumatoid Arthritis.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Adult; Area Under Curve; Arthritis, Rheumatoid; Biological Specimen Banks; Biomarkers; Body Mass Index; Carnitine; Chromatography, High Pressure Liquid; Discriminant Analysis; Fatty Acids; Female; Humans; Least-Squares Analysis; Lipids; Lysophosphatidylcholines; Metabolomics; Middle Aged; Principal Component Analysis; ROC Curve; Tryptophan

2016
Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism.
    Journal of immunology (Baltimore, Md. : 1950), 2017, 04-15, Volume: 198, Issue:8

    Topics: Arthritis, Rheumatoid; Cell Differentiation; Chromatography, High Pressure Liquid; Coculture Techniques; Fibroblasts; Humans; Immunoblotting; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymphocyte Activation; Osteoarthritis; Polymerase Chain Reaction; Synovial Membrane; Th1 Cells; Th17 Cells; Th2 Cells; Tryptophan

2017
Immunoadsorption with tryptophan columns: a therapeutic option for the treatment of rheumatoid arthritis with septic complications.
    Journal of clinical apheresis, 2009, Volume: 24, Issue:1

    Topics: Aged; Arthritis, Rheumatoid; Bacterial Infections; Humans; Immunosorbent Techniques; Sepsis; Spondylitis; Steroids; Treatment Outcome; Tryptophan

2009
Beyond immunosuppression: reconsidering indoleamine 2,3-dioxygenase as a pathogenic element of chronic inflammation.
    Immunotherapy, 2010, Volume: 2, Issue:3

    Topics: Arthritis, Rheumatoid; Autoimmunity; Chronic Disease; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Lupus Erythematosus, Systemic; Tryptophan

2010
Amelioration of rat collagen-induced arthritis through CD4+ T cells apoptosis and synovial interleukin-17 reduction by indoleamine 2,3-dioxygenase gene therapy.
    Human gene therapy, 2011, Volume: 22, Issue:2

    Topics: Adenoviridae; Animals; Ankle Joint; Apoptosis; Arthritis, Experimental; Arthritis, Rheumatoid; CD4-Positive T-Lymphocytes; Cell Line; Cell Proliferation; Genetic Therapy; Genetic Vectors; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interleukin-17; Kynurenine; Macrophages; Rats; Rats, Sprague-Dawley; Synovial Membrane; Tryptophan

2011
Tryptophan degradation and neopterin levels in treated rheumatoid arthritis patients.
    Clinical rheumatology, 2012, Volume: 31, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Disease Progression; Female; Humans; Kynurenine; Male; Middle Aged; Neopterin; Tryptophan; Tumor Necrosis Factor-alpha

2012
Increased degradation of tryptophan in blood of patients with rheumatoid arthritis.
    The Journal of rheumatology, 2003, Volume: 30, Issue:9

    Topics: Arthritis, Rheumatoid; Biomarkers; Chromatography, High Pressure Liquid; Cohort Studies; Female; Humans; Kynurenine; Male; Neopterin; Probability; Prognosis; Sensitivity and Specificity; Severity of Illness Index; Tryptophan

2003
Metabolism of tryptophan in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1962, Volume: 21

    Topics: Arthritis; Arthritis, Rheumatoid; Humans; Tryptophan

1962
Effect of pyridoxine on tryptophan metabolism in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1962, Volume: 21

    Topics: Arthritis; Arthritis, Rheumatoid; Humans; Pyridoxine; Tryptophan

1962
EXCRETION OF A TRYPTOPHAN METABOLITE IN RHEUMATOID ARTHRITIS.
    Arthritis and rheumatism, 1963, Volume: 6

    Topics: Arthritis, Rheumatoid; Humans; ortho-Aminobenzoates; Proteins; Tryptophan; Urine

1963
EXCRETION OF TRYPTOPHAN METABOLITES BY PATIENTS WITH RHEUMATOID ARTHRITIS.
    Arthritis and rheumatism, 1964, Volume: 7

    Topics: Arthritis; Arthritis, Rheumatoid; Biomedical Research; Chromatography; Gout; Hippurates; Indoles; Kynurenic Acid; Kynurenine; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Proteins; Psoriasis; Pyridines; Pyridoxine; Spondylitis; Tryptophan; Urine; Xanthurenates

1964
THE TYROSINE, TRYPTOPHAN AND PROTEIN CONTENT OF HUMAN PAROTID SALIVA IN ORAL AND SYSTEMIC DISEASE. USE OF ULTRAVIOLET ABSORPTION TECHNICS.
    International series of monographs on oral biology, 1964, Volume: 3

    Topics: Albinism; Arthritis, Rheumatoid; Biomedical Research; Dental Caries; Gingival Diseases; Humans; Parotid Gland; Periodontal Diseases; Proteins; Saliva; Salivation; Sialorrhea; Sjogren's Syndrome; Spectrum Analysis; Tryptophan; Tyrosine; Uric Acid

1964
TRYPTOPHAN METABOLISM IN RHEUMATIC DISEASE.
    Arthritis and rheumatism, 1964, Volume: 7

    Topics: Amino Acids; Arthritis; Arthritis, Rheumatoid; Chromatography; Humans; Kynurenic Acid; Kynurenine; Lupus Erythematosus, Systemic; ortho-Aminobenzoates; Rheumatic Diseases; Scleroderma, Systemic; Tryptophan; Urine; Xanthurenates

1964
TRYPTOPHAN METABOLITE EXCRETION IN CONNECTIVE TISSUE DISEASES DEMONSTRATING A DIFFERENCE BETWEEN RHEUMATOID SPONDYLITIS AND RHEUMATOID ARTHRITIS.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 117

    Topics: Arthritis; Arthritis, Rheumatoid; Connective Tissue Diseases; Diagnosis, Differential; Humans; Kynurenine; Lupus Erythematosus, Systemic; Metabolism; Scleroderma, Systemic; Spondylitis; Spondylitis, Ankylosing; Tryptophan; Urine

1964
Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Arthritis, Rheumatoid; Case-Control Studies; Etidronic Acid; Female; Humans; Kynurenine; Methotrexate; Neopterin; Osteoporosis; Prednisolone; Raloxifene Hydrochloride; Receptors, Glutamate; Tryptophan

2003
Association of R602W in a protein tyrosine phosphatase gene with a high risk of rheumatoid arthritis in a British population: evidence for an early onset/disease severity effect.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:1

    Topics: Adult; Age of Onset; Arginine; Arthritis, Rheumatoid; England; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Mutation, Missense; Polymorphism, Single Nucleotide; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Protein Tyrosine Phosphatases; Severity of Illness Index; Tryptophan; White People

2005
The alpha 2 type IX collagen gene tryptophan polymorphism is not associated with rheumatoid arthritis in the Japanese population.
    Clinical rheumatology, 2006, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Collagen Type IX; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Humans; Japan; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Tryptophan

2006
Tryptophan degradation increases with stage in patients with rheumatoid arthritis.
    Clinical rheumatology, 2006, Volume: 25, Issue:3

    Topics: Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Health Status; Humans; Kynurenine; Male; Middle Aged; Neopterin; Severity of Illness Index; Tryptophan

2006
Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Dec-01, Volume: 177, Issue:11

    Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmunity; Blotting, Western; Chromatography, High Pressure Liquid; Dendritic Cells; Enzyme Inhibitors; Female; Gene Expression; Humans; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synovial Fluid; T-Lymphocytes; Tryptophan; Tryptophan-tRNA Ligase; Tumor Necrosis Factor-alpha

2006
Some anti-inflammatory activities of copper complexes of amino acids.
    International archives of allergy and applied immunology, 1981, Volume: 66, Issue:1

    Topics: Amino Acids; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carrageenan; Ceruloplasmin; Concanavalin A; Copper; Cystine; Dextrans; Histamine Release; Histidine; Isomerism; Rats; Tryptophan

1981
Treatment of adjuvant arthritis with nonsteroidal agents. A comparative study.
    Journal of the American Podiatry Association, 1980, Volume: 70, Issue:2

    Topics: Animals; Arthritis; Arthritis, Experimental; Arthritis, Rheumatoid; Indoleacetic Acids; Male; ortho-Aminobenzoates; Rats; Tryptophan; Xanthurenates

1980
Rheumatoid factors from patients with rheumatoid arthritis react with tryptophan 60 and 95, lysine 58, and arginine 97, on human beta 2-microglobulin.
    Arthritis and rheumatism, 1993, Volume: 36, Issue:7

    Topics: Amino Acid Sequence; Antibody Specificity; Arginine; Arthritis, Rheumatoid; Aspartic Acid; beta 2-Microglobulin; Chromatography, Affinity; Computers; Epitopes; Humans; Immunoglobulin A; Immunoglobulin Fc Fragments; Immunoglobulin G; Immunoglobulin M; Isoleucine; Lysine; Molecular Sequence Data; Rheumatoid Factor; Sequence Homology, Amino Acid; Tryptophan; Valine

1993
Cross-restriction of a T cell clone to HLA-DR alleles associated with rheumatoid arthritis: clues to arthritogenic peptide motifs.
    Arthritis and rheumatism, 1999, Volume: 42, Issue:5

    Topics: Alleles; Antigen-Presenting Cells; Arginine; Arthritis, Rheumatoid; Clone Cells; Cross Reactions; Glycine; HLA-DR Antigens; Humans; Lysine; Point Mutation; Protein Conformation; T-Lymphocytes; Tryptophan

1999
Tryptophan catabolism in synovial fluid of various arthropathies and its relationship with inflammatory cytokines.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Adult; Arthritis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cytokines; Enzyme-Linked Immunosorbent Assay; Gout; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interleukin-1; Interleukin-6; Interleukin-8; Leukocytes; Middle Aged; Neutrophils; Osteoarthritis; Synovial Fluid; Tryptophan; Tryptophan Oxygenase

1999
Possible relationship between pH of plasma and rheumatoid arthritis.
    Life sciences, 1976, May-01, Volume: 18, Issue:9

    Topics: Arthritis, Rheumatoid; Carrier Proteins; Humans; Hydrogen-Ion Concentration; Salicylates; Tryptophan

1976
Is alclofenac specific?
    Rheumatology and rehabilitation, 1976, Volume: 15, Issue:3

    Topics: Arthritis, Rheumatoid; Blood Proteins; Humans; Phenylacetates; Protein Binding; Serum Albumin; Sulfhydryl Compounds; Time Factors; Tryptophan

1976
[Investigations on the plasm amino acids of old patients with rheumatoid arthritis (author's transl)].
    Aktuelle Gerontologie, 1977, Volume: 7, Issue:12

    Topics: Aged; Aging; Amino Acids; Arginine; Arthritis, Rheumatoid; Chromatography, Ion Exchange; Cystathionine; Humans; Methylhistidines; Middle Aged; Threonine; Tryptophan

1977
Nyctotheroides puytoraci: stimulation of encystment in toads, Bufo regularis, injected with rheumatoid arthritis patients' urine.
    Experimental parasitology, 1979, Volume: 48, Issue:2

    Topics: Animals; Arthritis, Rheumatoid; Bufonidae; Ciliophora; Humans; Pyridoxine; Tryptophan

1979
Metabolic abnormalities of tryptophan and nicotinic acid in patients with rheumatoid arthritis.
    Rheumatology and rehabilitation, 1978, Volume: 17, Issue:4

    Topics: 3-Hydroxyanthranilic Acid; Arthritis, Rheumatoid; Feeding Behavior; Humans; Kynuramine; Niacinamide; Nicotinic Acids; Tryptophan; Xanthurenates

1978
A study of the influence of various antirheumatic drug regimens on serum acute-phase proteins, plasma tryptophan, and erythrocyte sedimentation rate in rheumatoid arthritis.
    Rheumatology and rehabilitation, 1975, Volume: 14, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Blood Sedimentation; C-Reactive Protein; Drug Therapy, Combination; Female; Gold Sodium Thiomalate; Haptoglobins; Humans; Indomethacin; Male; Middle Aged; Penicillamine; Phenylacetates; Tryptophan

1975
[Tryptophan-serotonin metabolism and its enzymatic effects in joint diseases].
    Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1979, Volume: 117, Issue:4

    Topics: Arthritis, Rheumatoid; Joint Diseases; Monoamine Oxidase; Osteoarthritis; Serotonin; Synovial Fluid; Tryptophan; Tryptophan Hydroxylase

1979
[Urinary xanthurenic acid levels].
    Acta vitaminologica et enzymologica, 1978, Volume: 32, Issue:5-6

    Topics: Age Factors; Aged; Alcoholism; Arthritis, Rheumatoid; Child; Contraceptives, Oral; Diabetes Mellitus; Epilepsy; Female; Humans; Isoniazid; Penicillamine; Pregnancy; Tryptophan; Xanthurenates

1978
Schizophrenia, rheumatoid arthritis and trytophan metabolism.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:6

    Topics: Arthritis, Rheumatoid; Female; Humans; Male; Methionine; Methylation; Monoamine Oxidase; Protein Binding; Schizophrenia; Serotonin; Synovial Fluid; Tryptamines; Tryptophan

1978
Protein binding of tolmetin.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:6

    Topics: Adult; Aged; Arthritis, Rheumatoid; Binding Sites; Binding, Competitive; Erythrocytes; Female; Humans; In Vitro Techniques; Male; Middle Aged; Oleic Acids; Plasma; Protein Binding; Pyrroles; Serum Albumin; Tolmetin; Tryptophan

1978
Tryptophan and rheumatic diseases.
    British medical journal, 1977, Aug-13, Volume: 2, Issue:6084

    Topics: Arthritis, Rheumatoid; Humans; Tryptophan

1977
Tryptophan metabolism in the joint diseases.
    Acta vitaminologica et enzymologica, 1975, Volume: 29, Issue:1-6

    Topics: Arthritis, Rheumatoid; Humans; Hydroxyindoleacetic Acid; Monoamine Oxidase; Osteoarthritis; Serotonin; Synovial Fluid; Tryptophan

1975
Copper chelates as possible active forms of the antiarthritic agents.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:1

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chelating Agents; Copper; Disease Models, Animal; Edema; Granuloma; Hydrocortisone; Lethal Dose 50; Mice; ortho-Aminobenzoates; Rats; Salicylates; Tryptophan; Ulcer

1976
Alterations in tryptophan metabolism in the toxic oil syndrome and in the eosinophilia-myalgia syndrome.
    The Journal of rheumatology, 1992, Volume: 19, Issue:1

    Topics: Arthritis, Rheumatoid; Biopterins; Brassica; Eosinophilia-Myalgia Syndrome; Fatty Acids, Monounsaturated; Humans; Kynurenine; Neopterin; Plant Oils; Quinolinic Acid; Quinolinic Acids; Rapeseed Oil; Reference Values; Scleroderma, Systemic; Syndrome; Tryptophan

1992
Rheumatoid arthritis and schizophrenia: are they mutually exclusive?
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:1

    Topics: Anti-Inflammatory Agents; Antipsychotic Agents; Arthritis, Rheumatoid; Endorphins; Environment; Humans; Prostaglandins; Schizophrenia; Serotonin; Tryptophan

1985
Extracorporeal hydrophobic amino acid adsorbent therapy in rheumatoid arthritis.
    Clinical rheumatology, 1987, Volume: 6, Issue:4

    Topics: Absorption; Adult; Aged; Antigen-Antibody Complex; Arthritis, Rheumatoid; Female; Gels; Humans; Male; Middle Aged; Phenylalanine; Plasmapheresis; Polyvinyl Alcohol; Rheumatoid Factor; Tryptophan

1987
Alteration of tryptophan metabolism in the synovial fluid of patients with rheumatoid arthritis and osteoarthritis.
    The Tohoku journal of experimental medicine, 1987, Volume: 153, Issue:2

    Topics: Arthritis, Rheumatoid; Humans; Osteoarthritis; Oxygenases; Synovial Fluid; Tryptophan; Tryptophan Oxygenase

1987
Total and free-plasma tryptophan concentrations in rheumatoid disease.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:7

    Topics: Adult; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Estrogens; Female; Humans; Indomethacin; Male; Middle Aged; Piperazines; Prednisolone; Protein Binding; Tryptophan; Ultrafiltration

1973
Tryptophan metabolism in man (with special reference to rheumatoid arthritis and scleroderma).
    Seminars in arthritis and rheumatism, 1973, Volume: 2, Issue:4

    Topics: Arthritis, Rheumatoid; Aspirin; Cystinuria; Drug Synergism; Edetic Acid; Humans; Kynurenic Acid; Kynurenine; Methods; Niacinamide; Penicillamine; Pyridoxine; Scleroderma, Systemic; Tryptophan; Xanthurenates

1973
[Biochemical anomalies in rheumatoid polyarthritis].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1967, Mar-20, Volume: 43, Issue:14

    Topics: Arthritis, Rheumatoid; Humans; Hydroxyproline; Phenylalanine; Tryptophan; Tyrosine

1967
[Influence of ACTH on the tryptophan--nicotinic acid pathway in normal subjects and those with rheumatoid arthritis].
    Acta vitaminologica et enzymologica, 1967, Volume: 21, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Arthritis, Rheumatoid; Humans; Kynurenine; Middle Aged; Nicotinic Acids; Pyridones; Tryptophan

1967
The displacement of L-tryptophan and dipeptides from bovine albumin in vitro and from human plasma in vivo by antirheumatic drugs.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Proteins; Cattle; Chloroquine; Dipeptides; Gold; Humans; Indomethacin; Phenylalanine; Phenylbutazone; Prednisolone; Protein Binding; Salicylates; Serum Albumin, Bovine; Tryptophan

1971
The relation between clinical anti-inflammatory activity and the displacement of L-tryptophan and a dipeptide from human serum in vitro.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:6

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dipeptides; Humans; Phenylalanine; Protein Binding; Tryptophan

1971
Proceedings: Plasma L-tryptophan concentrations in chronic rheumatic diseases and the effects of some antirheumatic drugs on the binding of the amino-acid to plasma proteins in vivo and in vitro.
    Rheumatology and rehabilitation, 1974, Volume: 13, Issue:2

    Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Blood Proteins; Child; Child, Preschool; Female; Hot Temperature; Humans; Male; Middle Aged; Osteoarthritis; Protein Binding; Protein Denaturation; Psoriasis; Rheumatic Diseases; Serum Albumin; Serum Albumin, Bovine; Spondylitis, Ankylosing; Tryptophan

1974
5-Hydroxytryptamine metabolism in joint diseases.
    The Tohoku journal of experimental medicine, 1974, Volume: 112, Issue:4

    Topics: Arthritis, Rheumatoid; Humans; Hydroxyindoleacetic Acid; Joint Diseases; Monoamine Oxidase; Osteoarthritis; Serotonin; Synovial Fluid; Tryptophan

1974
Tryptophan metabolism in rheumatoid neuropathies.
    Annals of the rheumatic diseases, 1972, Volume: 31, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Child; Child, Preschool; Electrophysiology; Female; Humans; Kynurenine; Male; Middle Aged; Neurologic Manifestations; Nicotinic Acids; ortho-Aminobenzoates; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Xanthurenates

1972
Antivitamin B6 effect of D-penicillamine.
    Annals of the New York Academy of Sciences, 1969, Sep-30, Volume: 166, Issue:1

    Topics: Arthritis, Rheumatoid; Humans; Kynurenine; Penicillamine; Pyridoxine; Rheumatoid Factor; Stereoisomerism; Tryptophan; Xanthurenates

1969
Tryptophan metabolism in the synovial fluid in rheumatoid arthritis and osteoarthritis.
    The Tohoku journal of experimental medicine, 1969, Volume: 99, Issue:1

    Topics: Arthritis, Rheumatoid; Blood Sedimentation; Humans; Kynurenic Acid; Kynurenine; Nicotinic Acids; ortho-Aminobenzoates; Osteoarthritis; Synovial Fluid; Tryptophan; Xanthurenates

1969
The arthritogenic effect of indole, skatole and other tryptophan metabolites in rabbits.
    The American journal of pathology, 1969, Volume: 57, Issue:3

    Topics: Animals; Arthritis; Arthritis, Rheumatoid; Cell Membrane; Indoles; Kynurenine; Lipid Metabolism; Rabbits; Skatole; Tryptophan

1969
[Discriminatory analysis of data on tryptophan metabolism in patients with rheumatoid arthritis and normal subjects after amino acid load test].
    Acta vitaminologica et enzymologica, 1970, Volume: 24, Issue:6

    Topics: Amino Acids; Analysis of Variance; Arthritis, Rheumatoid; Humans; Kynurenine; Tryptophan

1970
Mode of action of antirheumatic drugs.
    British medical journal, 1971, Jun-19, Volume: 2, Issue:5763

    Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Bilirubin; Binding Sites; Blood Proteins; Chloroquine; Female; Gold; Humans; Indomethacin; Jaundice; Male; Middle Aged; Phenylbutazone; Prednisolone; Pregnancy; Protein Binding; Tryptophan

1971
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 128, Issue:1

    Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufenamic Acid; Fluorine; Histamine; Histidine; Hot Temperature; Indomethacin; ortho-Aminobenzoates; Phenylalanine; Phenylbutazone; Protein Denaturation; Serine; Serum Albumin, Bovine; Solutions; Tryptophan; Tyrosine

1968
[Tryptophan metabolism in the synovial fluid in joint diseases].
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1969, Mar-01, Volume: 38, Issue:2

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child, Preschool; Chromatography, Paper; Female; Humans; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Osteoarthritis; Synovial Fluid; Tryptophan; Xanthurenates

1969
Urinary tryptophan metabolites in rheumatoid arthritis and some other diseases.
    Annals of the rheumatic diseases, 1966, Volume: 25, Issue:6

    Topics: Arthritis, Rheumatoid; Female; Humans; Hyaluronic Acid; Kynurenine; Male; ortho-Aminobenzoates; Pyridoxine; Tryptophan; Xanthurenates

1966