Page last updated: 2024-10-23

berberine and Rheumatoid Arthritis

berberine has been researched along with Rheumatoid Arthritis in 12 studies

Research Excerpts

ExcerptRelevanceReference
"Berberine may inhibit the gene expression and production of pro-inflammatory cytokines by mononuclear cells in rheumatoid arthritis and healthy individuals without affecting cell viability."8.02Berberine Inhibits the Gene Expression and Production of Proinflammatory Cytokines by Mononuclear Cells in Rheumatoid Arthritis and Healthy Individuals. ( Ghorbani, N; Mahmoudi, M; Rastin, M; Sahebari, M; Zamani, M; Zamani, S, 2021)
"Berberine is a nature-derived alkaloid compound with multiple pharmacological activities in different pathologies, including RA."6.72Efficacy of berberine in treatment of rheumatoid arthritis: From multiple targets to therapeutic potential. ( Huang, DN; Sun, H; Wang, XJ; Wu, FF; Zhang, AH, 2021)
"Berberine may potentially retard the progression of osteoporosis, osteoarthritis and rheumatoid arthritis."5.05Berberine and musculoskeletal disorders: The therapeutic potential and underlying molecular mechanisms. ( Chin, KY; Ima-Nirwana, S; Wong, SK, 2020)
"The purpose of this study was to evaluate the drug delivery and therapeutic potential of berberine (Br) loaded nanoformulation in rheumatoid arthritis (RA)-induced animal model."4.31Assessment of anti-arthritic activity of lipid matrix encased berberine in rheumatic animal model. ( Kumar, D; Mishra, N; Pal, RR; Pandey, AK; Parashar, P; Raj, R; Saraf, SA; Singh, N; Singh, P; Singh, S, 2023)
"Berberine may inhibit the gene expression and production of pro-inflammatory cytokines by mononuclear cells in rheumatoid arthritis and healthy individuals without affecting cell viability."4.02Berberine Inhibits the Gene Expression and Production of Proinflammatory Cytokines by Mononuclear Cells in Rheumatoid Arthritis and Healthy Individuals. ( Ghorbani, N; Mahmoudi, M; Rastin, M; Sahebari, M; Zamani, M; Zamani, S, 2021)
"Gefitinib-resistant (G-R) nonsmall-cell lung cancer (NSCLC) and rheumatoid arthritis (RA) were studied as conditions representative of malignant and proliferative diseases, respectively."3.88Suppression of Lipogenesis via Reactive Oxygen Species-AMPK Signaling for Treating Malignant and Proliferative Diseases. ( Fan, XX; Fu, J; He, JX; Huang, J; Jiang, ZB; Kam, RK; Leung, EL; Liu, L; Liu, ZQ; Lu, LL; Luo, LX; Wei, CL; Wu, JL; Xiao, DK; Xie, Y; Yao, XJ; Yuan, ZW; Zheng, YF; Zhou, YL, 2018)
"Berberine is a nature-derived alkaloid compound with multiple pharmacological activities in different pathologies, including RA."2.72Efficacy of berberine in treatment of rheumatoid arthritis: From multiple targets to therapeutic potential. ( Huang, DN; Sun, H; Wang, XJ; Wu, FF; Zhang, AH, 2021)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (50.00)24.3611
2020's6 (50.00)2.80

Authors

AuthorsStudies
Singh, N1
Pandey, AK1
Pal, RR1
Parashar, P1
Singh, P1
Mishra, N1
Kumar, D1
Raj, R1
Singh, S1
Saraf, SA1
Yue, M1
Tao, Y1
Fang, Y1
Lian, X1
Zhang, Q1
Xia, Y1
Wei, Z1
Dai, Y1
Sujitha, S2
Dinesh, P1
Rasool, M2
Ghorbani, N1
Sahebari, M1
Mahmoudi, M1
Rastin, M1
Zamani, S1
Zamani, M1
Vita, AA1
Aljobaily, H1
Lyons, DO1
Pullen, NA1
Huang, DN1
Wu, FF1
Zhang, AH1
Sun, H1
Wang, XJ1
Fan, XX1
Leung, EL1
Xie, Y1
Liu, ZQ1
Zheng, YF1
Yao, XJ1
Lu, LL1
Wu, JL1
He, JX1
Yuan, ZW1
Fu, J1
Wei, CL1
Huang, J1
Xiao, DK1
Luo, LX1
Jiang, ZB1
Zhou, YL1
Kam, RK1
Liu, L1
Qiu, H1
Sun, S1
Ma, X1
Cui, C1
Chen, G1
Liu, Z1
Li, H1
Liu, M1
Wong, SK1
Chin, KY1
Ima-Nirwana, S1
Wang, X1
He, X1
Zhang, CF1
Guo, CR1
Wang, CZ1
Yuan, CS1
Wang, XH1
Jiang, SM1
Sun, QW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-label Phase II Trial of Gefitinib and Berberine in Patients With Advanced Non-small Cell Lung Cancer and Activating EGFR Mutations[NCT03486496]Phase 250 participants (Anticipated)Interventional2018-06-05Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for berberine and Rheumatoid Arthritis

ArticleYear
Efficacy of berberine in treatment of rheumatoid arthritis: From multiple targets to therapeutic potential.
    Pharmacological research, 2021, Volume: 169

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Berberine; Humans

2021
Berberine and musculoskeletal disorders: The therapeutic potential and underlying molecular mechanisms.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Jul-15, Volume: 73

    Topics: Animals; Arthritis, Rheumatoid; Berberine; beta Catenin; Humans; Musculoskeletal Diseases; NF-kappa

2020

Other Studies

10 other studies available for berberine and Rheumatoid Arthritis

ArticleYear
Assessment of anti-arthritic activity of lipid matrix encased berberine in rheumatic animal model.
    Journal of microencapsulation, 2023, Volume: 40, Issue:4

    Topics: Animals; Arthritis, Rheumatoid; Berberine; Drug Carriers; Drug Delivery Systems; Lipids; Models, Ani

2023
The gut microbiota modulator berberine ameliorates collagen-induced arthritis in rats by facilitating the generation of butyrate and adjusting the intestinal hypoxia and nitrate supply.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:11

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Berberine; Butyrates; Female; Gastrointesti

2019
Berberine encapsulated PEG-coated liposomes attenuate Wnt1/β-catenin signaling in rheumatoid arthritis via miR-23a activation.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2020, Volume: 149

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Berberine; beta Catenin; Female; Liposomes;

2020
Berberine Inhibits the Gene Expression and Production of Proinflammatory Cytokines by Mononuclear Cells in Rheumatoid Arthritis and Healthy Individuals.
    Current rheumatology reviews, 2021, Volume: 17, Issue:1

    Topics: Adult; Arthritis, Rheumatoid; Berberine; Cells, Cultured; Gene Expression; Humans; Interleukin-1beta

2021
Berberine Delays Onset of Collagen-Induced Arthritis through T Cell Suppression.
    International journal of molecular sciences, 2021, Mar-29, Volume: 22, Issue:7

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; B-Lymphocytes; Berberine; Collagen Type II;

2021
Suppression of Lipogenesis via Reactive Oxygen Species-AMPK Signaling for Treating Malignant and Proliferative Diseases.
    Antioxidants & redox signaling, 2018, 02-10, Volume: 28, Issue:5

    Topics: AMP-Activated Protein Kinases; Arthritis, Rheumatoid; Berberine; Carcinoma, Non-Small-Cell Lung; Cel

2018
Jatrorrhizine Hydrochloride Suppresses Proliferation, Migration, and Secretion of Synoviocytes In Vitro and Ameliorates Rat Models of Rheumatoid Arthritis In Vivo.
    International journal of molecular sciences, 2018, May-18, Volume: 19, Issue:5

    Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Berberine; Cell Line; Cell Movement; Cell Prol

2018
Berberine coated mannosylated liposomes curtail RANKL stimulated osteoclastogenesis through the modulation of GSK3β pathway via upregulating miR-23a.
    International immunopharmacology, 2019, Volume: 74

    Topics: Aniline Compounds; Animals; Arthritis, Rheumatoid; Berberine; Cells, Cultured; Disease Models, Anima

2019
Anti-arthritic effect of berberine on adjuvant-induced rheumatoid arthritis in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 89

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Berberine; Cytokines; Gene Expression Regu

2017
Effects of berberine on human rheumatoid arthritis fibroblast-like synoviocytes.
    Experimental biology and medicine (Maywood, N.J.), 2011, Volume: 236, Issue:7

    Topics: Anti-Inflammatory Agents; Apoptosis; Arthritis, Rheumatoid; Berberine; Cell Cycle; Cell Cycle Protei

2011